Compile Data Set for Download or QSAR

Found 585 hits of ki data for polymerid = 8334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85027 (1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...) Show SMILES COc1ccc(CCCN2CCC(CCC(=O)c3cc(Cl)c(N)c4OCCOc34)CC2)cc1OC Show InChI InChI=1S/C27H35ClN2O5/c1-32-23-8-6-19(16-24(23)33-2)4-3-11-30-12-9-18(10-13-30)5-7-22(31)20-17-21(28)25(29)27-26(20)34-14-15-35-27/h6,8,16-18H,3-5,7,9-15,29H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	0.000580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85027 (1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3...) Show SMILES COc1ccc(CCCN2CCC(CCC(=O)c3cc(Cl)c(N)c4OCCOc34)CC2)cc1OC Show InChI InChI=1S/C27H35ClN2O5/c1-32-23-8-6-19(16-24(23)33-2)4-3-11-30-12-9-18(10-13-30)5-7-22(31)20-17-21(28)25(29)27-26(20)34-14-15-35-27/h6,8,16-18H,3-5,7,9-15,29H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	0.000630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85020 (5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-...) Show SMILES COc1[nH]c2ccc(F)cc2c1C(=O)OCC1CCN(CCN[S](C)(=O)=O)CC1 Show InChI InChI=1S/C19H26FN3O5S/c1-27-18-17(15-11-14(20)3-4-16(15)22-18)19(24)28-12-13-5-8-23(9-6-13)10-7-21-29(2,25)26/h3-4,11,13,21-22H,5-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem Patents	Article PubMed	0.000870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483188 (CHEMBL1632166) Show SMILES O=C(CCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1)OCc1ccccc1 Show InChI InChI=1S/C30H37N3O4/c34-27(37-22-24-9-2-1-3-10-24)13-6-7-16-32-18-14-23(15-19-32)21-31-29(35)28-25-11-4-5-12-26(25)33-17-8-20-36-30(28)33/h1-5,9-12,23H,6-8,13-22H2,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.00145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85026 (N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...) Show SMILES CCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C22H31N3O2/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85020 (5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-...) Show SMILES COc1[nH]c2ccc(F)cc2c1C(=O)OCC1CCN(CCN[S](C)(=O)=O)CC1 Show InChI InChI=1S/C19H26FN3O5S/c1-27-18-17(15-11-14(20)3-4-16(15)22-18)19(24)28-12-13-5-8-23(9-6-13)10-7-21-29(2,25)26/h3-4,11,13,21-22H,5-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem Patents	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 | NSC_121881 | SB204070) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP Ki Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysis				Eur J Med Chem 64: 629-37 (2013) Article DOI: 10.1016/j.ejmech.2013.03.060 BindingDB Entry DOI: 10.7270/Q27947NT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399614 (CHEMBL2181170) Show SMILES CCCN1CCC(COc2nc3c(F)cccc3c3ncccc23)CC1 Show InChI InChI=1S/C21H24FN3O/c1-2-11-25-12-8-15(9-13-25)14-26-21-17-6-4-10-23-19(17)16-5-3-7-18(22)20(16)24-21/h3-7,10,15H,2,8-9,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483175 (CHEMBL1632165) Show SMILES O=C(CCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1)OCc1ccccc1 Show InChI InChI=1S/C29H35N3O4/c33-26(36-21-23-8-2-1-3-9-23)12-6-15-31-17-13-22(14-18-31)20-30-28(34)27-24-10-4-5-11-25(24)32-16-7-19-35-29(27)32/h1-5,8-11,22H,6-7,12-21H2,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES CCCCN1CCC(COC(=O)c2cc(I)c(N)c3OCCOc23)CC1 Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50023377 (CHEMBL3329805) Show SMILES CC(C)CS(=O)(=O)Nc1ccc(CN2CCC(CNC(=O)c3c4OCCCn4c4ccccc34)CC2)cc1 Show InChI InChI=1S/C29H38N4O4S/c1-21(2)20-38(35,36)31-24-10-8-23(9-11-24)19-32-15-12-22(13-16-32)18-30-28(34)27-25-6-3-4-7-26(25)33-14-5-17-37-29(27)33/h3-4,6-11,21-22,31H,5,12-20H2,1-2H3,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranes				Bioorg Med Chem Lett 24: 4598-602 (2014) Article DOI: 10.1016/j.bmcl.2014.06.083 BindingDB Entry DOI: 10.7270/Q28W3FW7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85026 (N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...) Show SMILES CCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C22H31N3O2/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0525	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483174 (CHEMBL1632163) Show SMILES CC(C)(C)OC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C28H41N3O4/c1-28(2,3)35-24(32)12-5-4-8-15-30-17-13-21(14-18-30)20-29-26(33)25-22-10-6-7-11-23(22)31-16-9-19-34-27(25)31/h6-7,10-11,21H,4-5,8-9,12-20H2,1-3H3,(H,29,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0537	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 | NSC_121881 | SB204070) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP Ki Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483187 (CHEMBL1632169) Show SMILES CC(C)(C)C(=O)OCOC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C30H43N3O6/c1-30(2,3)29(36)39-21-38-25(34)12-5-4-8-15-32-17-13-22(14-18-32)20-31-27(35)26-23-10-6-7-11-24(23)33-16-9-19-37-28(26)33/h6-7,10-11,22H,4-5,8-9,12-21H2,1-3H3,(H,31,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.0646	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université de Paris-Sud Curated by PDSP Ki Database									J Neurochem 70: 2252-61 (1998) Article DOI: 10.1046/j.1471-4159.1998.70062252.x BindingDB Entry DOI: 10.7270/Q2Z036PW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0741	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Antagonistic activity at human 5HT4 receptor expressed in HEK293 cells				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.0780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4D receptor isoform expressed in COS-7 cells				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50327858 ((1-Butylpiperidin-4-yl)methyl 8-amino-7-iodo-2,3-d...) Show SMILES CCCCN1CCC(COC(=O)c2cc(I)c(N)c3OCCOc23)CC1 Show InChI InChI=1S/C19H27IN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by PDSP Ki Database									Naunyn Schmiedebergs Arch Pharmacol 363: 146-60 (2001) Article DOI: 10.1007/s002100000299 BindingDB Entry DOI: 10.7270/Q2222SBP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50398985 (CHEMBL2177130) Show SMILES CC(C)n1nc(C(=O)NCC2CCN(CCc3ccccc3)CC2)c2ccccc12 Show InChI InChI=1S/C25H32N4O/c1-19(2)29-23-11-7-6-10-22(23)24(27-29)25(30)26-18-21-13-16-28(17-14-21)15-12-20-8-4-3-5-9-20/h3-11,19,21H,12-18H2,1-2H3,(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Displacement of [3H](1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate from human 5HT4R expressed in HEK293 cells				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50023365 (CHEMBL3329814) Show SMILES OCC(O)CN1CCC(COC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C21H28N2O5/c24-13-16(25)12-22-9-6-15(7-10-22)14-28-21(26)19-17-4-1-2-5-18(17)23-8-3-11-27-20(19)23/h1-2,4-5,15-16,24-25H,3,6-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0794	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranes				Bioorg Med Chem Lett 24: 4598-602 (2014) Article DOI: 10.1016/j.bmcl.2014.06.083 BindingDB Entry DOI: 10.7270/Q28W3FW7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Neuroreport 8: 3189-96 (1997) Article DOI: 10.1097/00001756-199710200-00002 BindingDB Entry DOI: 10.7270/Q2TD9VWM
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 | NSC_121881 | SB204070) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP Ki Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85026 (N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...) Show SMILES CCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C22H31N3O2/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysis				Eur J Med Chem 64: 629-37 (2013) Article DOI: 10.1016/j.ejmech.2013.03.060 BindingDB Entry DOI: 10.7270/Q27947NT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50398983 (CHEMBL2179697) Show SMILES CC(C)n1nc(C(=O)NCC2CCN(CCc3ccccn3)CC2)c2ccccc12 Show InChI InChI=1S/C24H31N5O/c1-18(2)29-22-9-4-3-8-21(22)23(27-29)24(30)26-17-19-10-14-28(15-11-19)16-12-20-7-5-6-13-25-20/h3-9,13,18-19H,10-12,14-17H2,1-2H3,(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Displacement of [3H](1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate from human 5HT4R expressed in HEK293 cells				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Binding affinity was determined against cloned 5-hydroxytryptamine 4E receptor isoform expressed in C6 glial cells incubated with 0.2 nM [3H]-GR-113,...				J Med Chem 43: 3761-9 (2000) BindingDB Entry DOI: 10.7270/Q2CC0ZXH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM82505 (CAS_121881 | NSC_121881 | SB204070) Show SMILES CCCCN1CCC(COC(=O)c2cc(Cl)c(N)c3OCCOc23)CC1 Show InChI InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP Ki Database									J Neurochem 74: 478-89 (2000) Article DOI: 10.1046/j.1471-4159.2000.740478.x BindingDB Entry DOI: 10.7270/Q2DJ5D5Z
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483173 (CHEMBL1632157) Show SMILES CCOC(=O)CCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C24H33N3O4/c1-2-30-21(28)9-5-12-26-14-10-18(11-15-26)17-25-23(29)22-19-7-3-4-8-20(19)27-13-6-16-31-24(22)27/h3-4,7-8,18H,2,5-6,9-17H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483172 (CHEMBL1632158) Show SMILES COC(=O)CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C25H35N3O4/c1-31-22(29)10-3-2-6-13-27-15-11-19(12-16-27)18-26-24(30)23-20-8-4-5-9-21(20)28-14-7-17-32-25(23)28/h4-5,8-9,19H,2-3,6-7,10-18H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50492064 (CHEMBL2391994) Show SMILES CC(C)(C(O)=O)c1ccc(CN2CCC(COC(=O)c3c4OCCCn4c4ccccc34)CC2)cc1 Show InChI InChI=1S/C29H34N2O5/c1-29(2,28(33)34)22-10-8-20(9-11-22)18-30-15-12-21(13-16-30)19-36-27(32)25-23-6-3-4-7-24(23)31-14-5-17-35-26(25)31/h3-4,6-11,21H,5,12-19H2,1-2H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5-HT4B receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysis				Eur J Med Chem 64: 629-37 (2013) Article DOI: 10.1016/j.ejmech.2013.03.060 BindingDB Entry DOI: 10.7270/Q27947NT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483186 (CHEMBL1632167) Show SMILES O=C(CCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1)OCc1ccccc1 Show InChI InChI=1S/C31H39N3O4/c35-28(38-23-25-10-3-1-4-11-25)14-5-2-8-17-33-19-15-24(16-20-33)22-32-30(36)29-26-12-6-7-13-27(26)34-18-9-21-37-31(29)34/h1,3-4,6-7,10-13,24H,2,5,8-9,14-23H2,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UPR 9023 Curated by PDSP Ki Database									Eur J Pharmacol 298: 165-74 (1996) Article DOI: 10.1016/0014-2999(95)00786-5 BindingDB Entry DOI: 10.7270/Q2GF0S1D
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM29525 (3H-GR113808 | CHEMBL518682 | GR 113808 | [3H] GR 1...) Show SMILES Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc12 Show InChI InChI=1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP Ki Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85020 (5-Fluoro-2-methoxy-1H-indole-3-carboxylic acid [1-...) Show SMILES COc1[nH]c2ccc(F)cc2c1C(=O)OCC1CCN(CCN[S](C)(=O)=O)CC1 Show InChI InChI=1S/C19H26FN3O5S/c1-27-18-17(15-11-14(20)3-4-16(15)22-18)19(24)28-12-13-5-8-23(9-6-13)10-7-21-29(2,25)26/h3-4,11,13,21-22H,5-10,12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem Patents	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research Foundation Curated by PDSP Ki Database									J Neurochem 69: 1810-9 (1997) Article DOI: 10.1046/j.1471-4159.1997.69051810.x BindingDB Entry DOI: 10.7270/Q2Z60MMW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50398598 (CHEMBL2152922) Show SMILES OC1(CN2CCC(COc3noc4cccc(O[C@@H]5CCOC5)c34)CC2)CCOCC1 |r| Show InChI InChI=1S/C23H32N2O6/c26-23(7-12-27-13-8-23)16-25-9-4-17(5-10-25)14-29-22-21-19(30-18-6-11-28-15-18)2-1-3-20(21)31-24-22/h1-3,17-18,26H,4-16H2/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4D receptor expressed in HEK293 cells after 30 mins by liquid scintillation counting				J Med Chem 55: 9240-54 (2012) Article DOI: 10.1021/jm300953p BindingDB Entry DOI: 10.7270/Q2FQ9XRB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM85026 (N-(1-Butylpiperidine-4-ylmethyl)-1,2-(trimethylene...) Show SMILES CCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C22H31N3O2/c1-2-3-11-24-13-9-17(10-14-24)16-23-21(26)20-18-7-4-5-8-19(18)25-12-6-15-27-22(20)25/h4-5,7-8,17H,2-3,6,9-16H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	0.158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Displacement of [3H](1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate from human 5HT4R expressed in HEK293 cells				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50398981 (CHEMBL2179699) Show SMILES CC(C)n1nc(C(=O)NCC2CCN(CCC3CCCCC3)CC2)c2ccccc12 Show InChI InChI=1S/C25H38N4O/c1-19(2)29-23-11-7-6-10-22(23)24(27-29)25(30)26-18-21-13-16-28(17-14-21)15-12-20-8-4-3-5-9-20/h6-7,10-11,19-21H,3-5,8-9,12-18H2,1-2H3,(H,26,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Displacement of [3H](1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate from human 5HT4R expressed in HEK293 cells				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50483171 (CHEMBL1632159) Show SMILES COC(=O)CCCCCCCCCN1CCC(CNC(=O)c2c3OCCCn3c3ccccc23)CC1 Show InChI InChI=1S/C29H43N3O4/c1-35-26(33)14-7-5-3-2-4-6-10-17-31-19-15-23(16-20-31)22-30-28(34)27-24-12-8-9-13-25(24)32-18-11-21-36-29(27)32/h8-9,12-13,23H,2-7,10-11,14-22H2,1H3,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Drug Discovery Laboratory AS Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4 receptor expressed in HEK293 cells by liquid scintillation counting				Bioorg Med Chem 18: 8600-13 (2010) Article DOI: 10.1016/j.bmc.2010.10.011 BindingDB Entry DOI: 10.7270/Q2FR00GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50023379 (CHEMBL3329803) Show SMILES CS(=O)(=O)Nc1ccc(CN2CCC(CNC(=O)c3c4OCCCn4c4ccccc34)CC2)cc1 Show InChI InChI=1S/C26H32N4O4S/c1-35(32,33)28-21-9-7-20(8-10-21)18-29-14-11-19(12-15-29)17-27-25(31)24-22-5-2-3-6-23(22)30-13-4-16-34-26(24)30/h2-3,5-10,19,28H,4,11-18H2,1H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranes				Bioorg Med Chem Lett 24: 4598-602 (2014) Article DOI: 10.1016/j.bmcl.2014.06.083 BindingDB Entry DOI: 10.7270/Q28W3FW7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50023375 (CHEMBL3329807) Show SMILES CS(=O)(=O)Nc1ccc(CN2CCC(CNC(=O)c3cccc4OCCOc34)CC2)cc1 Show InChI InChI=1S/C23H29N3O5S/c1-32(28,29)25-19-7-5-18(6-8-19)16-26-11-9-17(10-12-26)15-24-23(27)20-3-2-4-21-22(20)31-14-13-30-21/h2-8,17,25H,9-16H2,1H3,(H,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranes				Bioorg Med Chem Lett 24: 4598-602 (2014) Article DOI: 10.1016/j.bmcl.2014.06.083 BindingDB Entry DOI: 10.7270/Q28W3FW7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50023373 (CHEMBL3329809) Show SMILES CC(C)CS(=O)(=O)Nc1ccc(CN2CCC(CNC(=O)c3cccc4OCCOc34)CC2)cc1 Show InChI InChI=1S/C26H35N3O5S/c1-19(2)18-35(31,32)28-22-8-6-21(7-9-22)17-29-12-10-20(11-13-29)16-27-26(30)23-4-3-5-24-25(23)34-15-14-33-24/h3-9,19-20,28H,10-18H2,1-2H3,(H,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranes				Bioorg Med Chem Lett 24: 4598-602 (2014) Article DOI: 10.1016/j.bmcl.2014.06.083 BindingDB Entry DOI: 10.7270/Q28W3FW7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50023376 (CHEMBL3329806) Show SMILES O=C(NCC1CCN(Cc2ccc(NS(=O)(=O)C3CCCCC3)cc2)CC1)c1c2OCCCn2c2ccccc12 Show InChI InChI=1S/C31H40N4O4S/c36-30(29-27-9-4-5-10-28(27)35-17-6-20-39-31(29)35)32-21-23-15-18-34(19-16-23)22-24-11-13-25(14-12-24)33-40(37,38)26-7-2-1-3-8-26/h4-5,9-14,23,26,33H,1-3,6-8,15-22H2,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Oslo Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from human 5HT4b receptor expressed in HEK293 cell membranes				Bioorg Med Chem Lett 24: 4598-602 (2014) Article DOI: 10.1016/j.bmcl.2014.06.083 BindingDB Entry DOI: 10.7270/Q28W3FW7
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50398975 (CHEMBL2179706) Show SMILES CC(C)n1nc(C(=O)NCC2CCN(CCc3ccc(N)cc3)CC2)c2ccccc12 Show InChI InChI=1S/C25H33N5O/c1-18(2)30-23-6-4-3-5-22(23)24(28-30)25(31)27-17-20-12-15-29(16-13-20)14-11-19-7-9-21(26)10-8-19/h3-10,18,20H,11-17,26H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Angelini Santa Palomba Research Center Curated by ChEMBL					Assay Description Displacement of [3H](1-(2-(methylsulfonamido)ethyl)piperidin-4-yl)methyl 1-methyl-1H-indole-3-carboxylate from human 5HT4R expressed in HEK293 cells				J Med Chem 55: 9446-66 (2012) Article DOI: 10.1021/jm300573d BindingDB Entry DOI: 10.7270/Q27082JT
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50399621 (CHEMBL2181166) Show SMILES Fc1cccc2c1nc(OCC1CCN(CCCc3ccc(I)cc3)CC1)c1cccnc21 Show InChI InChI=1S/C27H27FIN3O/c28-24-7-1-5-22-25-23(6-2-14-30-25)27(31-26(22)24)33-18-20-12-16-32(17-13-20)15-3-4-19-8-10-21(29)11-9-19/h1-2,5-11,14,20H,3-4,12-13,15-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Caen Basse-Normandie Curated by ChEMBL					Assay Description Displacement of radioligand from human 5HT4R by Cerep protocol based assay				J Med Chem 55: 9693-707 (2012) Article DOI: 10.1021/jm300943r BindingDB Entry DOI: 10.7270/Q2ZC8417
					More data for this Ligand-Target Pair

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