Found 377 hits of ic50 for UniProtKB: P11388 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50142519
(CHEMBL47027 | N-[2-(3,4,5-triihydroxy-benzoylamino...)Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccccc1NC(=O)c1cc(O)c(O)c(O)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-3-1-2-4-12(11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30) | PDB
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PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University
Curated by ChEMBL
| |
Bioorg Med Chem Lett 14: 1669-72 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.060
BindingDB Entry DOI: 10.7270/Q2GX4B0X |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50123623
((R)-13-(3-aminopyrrolidin-1-yl)-12-fluoro-10-oxo-1...)Show SMILES N[C@@H]1CCN(C1)c1c(F)cc2c3c1oc1c4ccc5ccccc5c4ccc1n3cc(C(O)=O)c2=O Show InChI InChI=1S/C28H20FN3O4/c29-21-11-19-23-27(24(21)31-10-9-15(30)12-31)36-26-18-6-5-14-3-1-2-4-16(14)17(18)7-8-22(26)32(23)13-20(25(19)33)28(34)35/h1-8,11,13,15H,9-10,12,30H2,(H,34,35)/t15-/m1/s1 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
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| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Toulouse
Curated by ChEMBL
| Assay Description
Induction of poison effect at DNA topoisomerase 2 by G-quadruplex interaction polymerase stop assay |
Bioorg Med Chem 17: 5396-407 (2009)
Article DOI: 10.1016/j.bmc.2009.06.053
BindingDB Entry DOI: 10.7270/Q21N816M |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50142517
(CHEMBL47885 | N-[4-(3,4,5-triihydroxy-benzoylamino...)Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1ccc(NC(=O)c2cc(O)c(O)c(O)c2)cc1 Show InChI InChI=1S/C20H16N2O8/c23-13-5-9(6-14(24)17(13)27)19(29)21-11-1-2-12(4-3-11)22-20(30)10-7-15(25)18(28)16(26)8-10/h1-8,23-28H,(H,21,29)(H,22,30) | PDB
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| CHEMBL
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| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University
Curated by ChEMBL
| |
Bioorg Med Chem Lett 14: 1669-72 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.060
BindingDB Entry DOI: 10.7270/Q2GX4B0X |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50142507
(CHEMBL47526 | N-[3-(3,4,5-triihydroxy-benzoylamino...)Show SMILES Oc1cc(cc(O)c1O)C(=O)Nc1cccc(NC(=O)c2cc(O)c(O)c(O)c2)c1 Show InChI InChI=1S/C20H16N2O8/c23-13-4-9(5-14(24)17(13)27)19(29)21-11-2-1-3-12(8-11)22-20(30)10-6-15(25)18(28)16(26)7-10/h1-8,23-28H,(H,21,29)(H,22,30) | PDB
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| CHEMBL
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| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University
Curated by ChEMBL
| |
Bioorg Med Chem Lett 14: 1669-72 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.060
BindingDB Entry DOI: 10.7270/Q2GX4B0X |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50123624
((S)-13-(3-aminopyrrolidin-1-yl)-12-fluoro-10-oxo-1...)Show SMILES N[C@H]1CCN(C1)c1c(F)cc2c3c1oc1c4ccc5ccccc5c4ccc1n3cc(C(O)=O)c2=O Show InChI InChI=1S/C28H20FN3O4/c29-21-11-19-23-27(24(21)31-10-9-15(30)12-31)36-26-18-6-5-14-3-1-2-4-16(14)17(18)7-8-22(26)32(23)13-20(25(19)33)28(34)35/h1-8,11,13,15H,9-10,12,30H2,(H,34,35)/t15-/m0/s1 | PDB
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| CHEMBL
PC cid
PC sid
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| Article
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| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Toulouse
Curated by ChEMBL
| Assay Description
Induction of poison effect at DNA topoisomerase 2 by G-quadruplex interaction polymerase stop assay |
Bioorg Med Chem 17: 5396-407 (2009)
Article DOI: 10.1016/j.bmc.2009.06.053
BindingDB Entry DOI: 10.7270/Q21N816M |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50139117
(CHEMBL3759668)Show SMILES CN(C)CCCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc(C#N)c(nc12)C#N Show InChI InChI=1S/C21H21N9/c1-29(2)9-5-6-10-30-19(24)17(20-26-13-7-3-4-8-14(13)27-20)18-21(30)28-16(12-23)15(11-22)25-18/h3-4,7-8H,5-6,9-10,24H2,1-2H3,(H,26,27) | PDB
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| CHEMBL
PC cid
PC sid
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| PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University
Curated by ChEMBL
| Assay Description
Inhibition of purified human topoisomerase 2-mediated relaxation of supercoiled pBR322 DNA at 50 uM incubated for 30 mins in presence of 1 mM ATP by ... |
J Med Chem 59: 238-52 (2016)
BindingDB Entry DOI: 10.7270/Q27946HM |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM22984
((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r| Show InChI InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University
Curated by ChEMBL
| Assay Description
Inhibition human placenta topoisomerase 2 assessed as conversion of supercoiled pBR322 DNA to relaxed form |
J Nat Prod 64: 204-7 (2001)
BindingDB Entry DOI: 10.7270/Q2W37W21 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM22984
((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r| Show InChI InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 | PDB
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| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University
Curated by ChEMBL
| Assay Description
Inhibition human placenta topoisomerase 2 assessed as conversion of catenated kinetoplast DNA to minicircle monomer |
J Nat Prod 64: 204-7 (2001)
BindingDB Entry DOI: 10.7270/Q2W37W21 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50349933
(CHEMBL1812144)Show SMILES ClC1=C2OC=C(CC=C)c3cccc(C(=O)C1=O)c23 |c:1,t:4| Show InChI InChI=1S/C15H9ClO3/c1-2-4-8-7-19-15-11-9(8)5-3-6-10(11)13(17)14(18)12(15)16/h2-3,5-7H,1,4H2 | PDB
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PC sid
UniChem
| Article
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| n/a | n/a | 1.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis |
Eur J Med Chem 46: 3339-47 (2011)
Article DOI: 10.1016/j.ejmech.2011.04.059
BindingDB Entry DOI: 10.7270/Q2513ZJD |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50295258
(CHEMBL571444 | N2-(benzo[d]thiazol-6-yl)-N6-tert-b...)Show InChI InChI=1S/C16H17N7S/c1-16(2,3)23-14-12-13(18-7-17-12)21-15(22-14)20-9-4-5-10-11(6-9)24-8-19-10/h4-8H,1-3H3,(H3,17,18,20,21,22,23) | PDB
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| Article
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| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of ATPase activity of human topoisomerase 2 alpha |
Bioorg Med Chem Lett 19: 4014-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.034
BindingDB Entry DOI: 10.7270/Q23J3D1M |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50349934
(CHEMBL1812139)Show InChI InChI=1S/C13H10O3/c1-7-6-16-11-5-10(14)13(15)9-4-2-3-8(7)12(9)11/h2-5,7H,6H2,1H3 | PDB
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| CHEMBL
PC cid
PC sid
UniChem
| Article
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| n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis |
Eur J Med Chem 46: 3339-47 (2011)
Article DOI: 10.1016/j.ejmech.2011.04.059
BindingDB Entry DOI: 10.7270/Q2513ZJD |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM81544
(BNS-22)Show SMILES CCCc1cc(=O)oc2c(C(=O)N3CCCc4ccccc34)c(OC)cc(OC)c12 Show InChI InChI=1S/C24H25NO5/c1-4-8-16-13-20(26)30-23-21(16)18(28-2)14-19(29-3)22(23)24(27)25-12-7-10-15-9-5-6-11-17(15)25/h5-6,9,11,13-14H,4,7-8,10,12H2,1-3H3 | PDB
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| Article
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| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | 7.5 | 4 |
RIKEN Advanced Science Institute
| Assay Description
In vitro inhibition of TOP2 alpha activity by BNS derivatives. |
Chem Biol 18: 743-51 (2011)
Article DOI: 10.1016/j.chembiol.2011.03.012
BindingDB Entry DOI: 10.7270/Q2N58JWJ |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM22984
((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r| Show InChI InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 | PDB
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| Article
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| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"Aldo Moro"
Curated by ChEMBL
| Assay Description
Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast DNA after 60 mins by agarose gel electrophoresis |
Eur J Med Chem 123: 704-717 (2016)
Article DOI: 10.1016/j.ejmech.2016.07.063
BindingDB Entry DOI: 10.7270/Q2TQ63HJ |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM22984
((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)Show SMILES COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO |r| Show InChI InChI=1S/C27H29NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,17-,22+,27-/m0/s1 | PDB
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| Article
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| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| |
Bioorg Med Chem 25: 2625-2634 (2017)
Article DOI: 10.1016/j.bmc.2017.03.019 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50004233
(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3 | PDB
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| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford
Curated by ChEMBL
| Assay Description
Inhibition of topoisomerase 2 |
Proc Natl Acad Sci USA 104: 20523-8 (2007)
Checked by Author
Article DOI: 10.1073/pnas.0708800104
BindingDB Entry DOI: 10.7270/Q2DB82RH |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50242374
(CHEMBL505529 | topostatin)Show SMILES CCCCCCCC(C)CC=C(C)C=CC(=O)C(C)CCC1OC(=O)[C@H](CC(OS(O)(=O)=O)C(N)=O)NC(=O)[C@@H](C)CNC(=O)C(=C)NC(=O)C1C |r,w:14.14,10.9| Show InChI InChI=1S/C36H58N4O11S/c1-8-9-10-11-12-13-22(2)14-15-23(3)16-18-29(41)24(4)17-19-30-26(6)34(44)39-27(7)35(45)38-21-25(5)33(43)40-28(36(46)50-30)20-31(32(37)42)51-52(47,48)49/h15-16,18,22,24-26,28,30-31H,7-14,17,19-21H2,1-6H3,(H2,37,42)(H,38,45)(H,39,44)(H,40,43)(H,47,48,49)/t22?,24?,25-,26?,28-,30?,31?/m0/s1 | PDB
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| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University
Curated by ChEMBL
| Assay Description
Inhibition human placenta topoisomerase 2 assessed as conversion of catenated kinetoplast DNA to minicircle monomer |
J Nat Prod 64: 204-7 (2001)
BindingDB Entry DOI: 10.7270/Q2W37W21 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50242374
(CHEMBL505529 | topostatin)Show SMILES CCCCCCCC(C)CC=C(C)C=CC(=O)C(C)CCC1OC(=O)[C@H](CC(OS(O)(=O)=O)C(N)=O)NC(=O)[C@@H](C)CNC(=O)C(=C)NC(=O)C1C |r,w:14.14,10.9| Show InChI InChI=1S/C36H58N4O11S/c1-8-9-10-11-12-13-22(2)14-15-23(3)16-18-29(41)24(4)17-19-30-26(6)34(44)39-27(7)35(45)38-21-25(5)33(43)40-28(36(46)50-30)20-31(32(37)42)51-52(47,48)49/h15-16,18,22,24-26,28,30-31H,7-14,17,19-21H2,1-6H3,(H2,37,42)(H,38,45)(H,39,44)(H,40,43)(H,47,48,49)/t22?,24?,25-,26?,28-,30?,31?/m0/s1 | PDB
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| CHEMBL
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PC cid
PC sid
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| PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kumamoto University
Curated by ChEMBL
| Assay Description
Inhibition human placenta topoisomerase 2 assessed as conversion of supercoiled pBR322 DNA to relaxed form |
J Nat Prod 64: 204-7 (2001)
BindingDB Entry DOI: 10.7270/Q2W37W21 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50183475
(5-(3-Amino-propylamino)-7,10-dihydroxy-2-[2-(2-hyd...)Show SMILES NCCCNc1ccc2n(CCNCCO)nc3-c4c(O)ccc(O)c4C(=O)c1c23 Show InChI InChI=1S/C21H25N5O4/c22-6-1-7-24-12-2-3-13-17-16(12)21(30)19-15(29)5-4-14(28)18(19)20(17)25-26(13)10-8-23-9-11-27/h2-5,23-24,27-29H,1,6-11,22H2 | PDB
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| Article
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| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2alpha decantation activity |
Bioorg Med Chem 16: 3959-68 (2008)
Article DOI: 10.1016/j.bmc.2008.01.033
BindingDB Entry DOI: 10.7270/Q2T72H7K |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50400785
(CHEMBL449350)Show SMILES CC(C)C(=C)CCC([C@H]1CC[C@@]2(C)C3=CC[C@H]4C(C)(C)C(=O)CC[C@]4(C)C3=CC[C@]12C)C(O)=O |c:28,t:13| Show InChI InChI=1S/C31H46O3/c1-19(2)20(3)9-10-21(27(33)34)22-13-17-31(8)24-11-12-25-28(4,5)26(32)15-16-29(25,6)23(24)14-18-30(22,31)7/h11,14,19,21-22,25H,3,9-10,12-13,15-18H2,1-2,4-8H3,(H,33,34)/t21?,22-,25+,29-,30-,31+/m1/s1 | PDB
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| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Inhibition of topoisomerase 2 |
J Nat Prod 75: 2016-2044 (2012)
Article DOI: 10.1021/np300412h
BindingDB Entry DOI: 10.7270/Q2HX1DTP |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50240132
(CHEMBL4090898) | PDB
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| CHEMBL
PC cid
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UniChem
| Article
PubMed
| n/a | n/a | 4.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| |
Bioorg Med Chem 25: 2625-2634 (2017)
Article DOI: 10.1016/j.bmc.2017.03.019 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50349932
(CHEMBL1812137)Show SMILES OC1(Cc2ccccc2)COC2=CC(=O)C(=O)c3cccc1c23 |t:12| Show InChI InChI=1S/C19H14O4/c20-15-9-16-17-13(18(15)21)7-4-8-14(17)19(22,11-23-16)10-12-5-2-1-3-6-12/h1-9,22H,10-11H2 | PDB
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| n/a | n/a | 4.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresis |
Eur J Med Chem 46: 3339-47 (2011)
Article DOI: 10.1016/j.ejmech.2011.04.059
BindingDB Entry DOI: 10.7270/Q2513ZJD |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50152149
(CHEMBL3780961)Show InChI InChI=1S/C18H17N2.HI/c1-12-15-11-19(2)9-8-13(15)10-17-18(12)14-6-4-5-7-16(14)20(17)3;/h4-11H,1-3H3;1H/q+1;/p-1 | PDB
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| PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vanderbilt University School of Medicine
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human DNA topoisomerase 2alpha expressed in topoisomerase1 deficient Saccharomyces cerevisiae JEL1 assessed as inhibition o... |
Bioorg Med Chem Lett 26: 1809-12 (2016)
BindingDB Entry DOI: 10.7270/Q2MC91WG |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50246439
(CHEMBL4082686) | PDB
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| Article
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| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto Italiano di Tecnologia
Curated by ChEMBL
| |
J Med Chem 61: 1375-1379 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01388 |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50218559
(CHEMBL64993)Show SMILES CC1OC(Oc2c(O)c3C(=O)c4ccccc4C(=O)c3c3cccnc23)C(F)C(O)C1O | PDB
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| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Bioorganic Chemistry
Curated by ChEMBL
| |
Bioorg Med Chem Lett 10: 203-7 (2000)
|
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50208207
(CHEMBL3883611) | PDB
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UniChem
| Article
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| n/a | n/a | 5.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"Aldo Moro"
Curated by ChEMBL
| Assay Description
Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast DNA after 60 mins by agarose gel electrophoresis |
Eur J Med Chem 123: 704-717 (2016)
Article DOI: 10.1016/j.ejmech.2016.07.063
BindingDB Entry DOI: 10.7270/Q2TQ63HJ |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM67690
(1,4-bis[2-(2-hydroxyethylamino)ethylamino]-5,8-bis...)Show SMILES OCCNCCNc1ccc(NCCNCCO)c2C(=O)c3c(O)ccc(O)c3C(=O)c12 Show InChI InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2 | PDB
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| Article
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| n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2alpha decantation activity |
Bioorg Med Chem 16: 3959-68 (2008)
Article DOI: 10.1016/j.bmc.2008.01.033
BindingDB Entry DOI: 10.7270/Q2T72H7K |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50240135
(CHEMBL4066762) | PDB
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| n/a | n/a | 5.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| |
Bioorg Med Chem 25: 2625-2634 (2017)
Article DOI: 10.1016/j.bmc.2017.03.019 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50298272
(CHEMBL575610 | N,N'-Bis(2-((2-(7-chloro-6-oxo-6H-d...)Show SMILES CN(CCNC(=O)CCC(=O)NCCN(C)CCn1nc2-c3cccc(Cl)c3C(=O)c3cccc1c23)CCn1nc2-c3cccc(Cl)c3C(=O)c3cccc1c23 Show InChI InChI=1S/C42H40Cl2N8O4/c1-49(21-23-51-31-13-5-9-27-37(31)39(47-51)25-7-3-11-29(43)35(25)41(27)55)19-17-45-33(53)15-16-34(54)46-18-20-50(2)22-24-52-32-14-6-10-28-38(32)40(48-52)26-8-4-12-30(44)36(26)42(28)56/h3-14H,15-24H2,1-2H3,(H,45,53)(H,46,54) | PDB
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| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba
Curated by ChEMBL
| Assay Description
Inhibition of decatenation activity of human topoisomerase 2alpha |
Bioorg Med Chem 17: 4575-82 (2009)
Article DOI: 10.1016/j.bmc.2009.04.072
BindingDB Entry DOI: 10.7270/Q28915XR |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50240137
(CHEMBL4062965) | PDB
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| n/a | n/a | 7.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National and Kapodistrian University of Athens
Curated by ChEMBL
| |
Bioorg Med Chem 25: 2625-2634 (2017)
Article DOI: 10.1016/j.bmc.2017.03.019 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50251129
(7-Chloro-2-{2-[(2-hydroxy-ethyl)-methyl-amino]-eth...)Show InChI InChI=1S/C19H18ClN3O2/c1-22(10-11-24)8-9-23-15-7-3-5-13-17(15)18(21-23)12-4-2-6-14(20)16(12)19(13)25/h2-7,24H,8-11H2,1H3 | PDB
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| n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2alpha decantation activity |
Bioorg Med Chem 16: 3959-68 (2008)
Article DOI: 10.1016/j.bmc.2008.01.033
BindingDB Entry DOI: 10.7270/Q2T72H7K |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50240660
(7-Hydroxy-2-[2-(2-hydroxy-ethylamino)-ethyl]-5-[2-...)Show SMILES OCCNCCNc1ccc2n(CCNCCO)nc3-c4cccc(O)c4C(=O)c1c23 Show InChI InChI=1S/C22H27N5O4/c28-12-9-23-6-7-25-15-4-5-16-20-19(15)22(31)18-14(2-1-3-17(18)30)21(20)26-27(16)11-8-24-10-13-29/h1-5,23-25,28-30H,6-13H2 | PDB
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| n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2alpha decantation activity |
Bioorg Med Chem 16: 3959-68 (2008)
Article DOI: 10.1016/j.bmc.2008.01.033
BindingDB Entry DOI: 10.7270/Q2T72H7K |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM81549
(BNS-65)Show SMILES COC(=O)Cc1cc(=O)oc2c(C(=O)N3CCCc4ccccc34)c(OC)cc(OC)c12 Show InChI InChI=1S/C24H23NO7/c1-29-17-13-18(30-2)22(23-21(17)15(11-19(26)31-3)12-20(27)32-23)24(28)25-10-6-8-14-7-4-5-9-16(14)25/h4-5,7,9,12-13H,6,8,10-11H2,1-3H3 | PDB
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| n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | 7.5 | 4 |
RIKEN Advanced Science Institute
| Assay Description
In vitro inhibition of TOP2 alpha activity by BNS derivatives. |
Chem Biol 18: 743-51 (2011)
Article DOI: 10.1016/j.chembiol.2011.03.012
BindingDB Entry DOI: 10.7270/Q2N58JWJ |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50295259
(CHEMBL549357 | N2-(benzo[d]thiazol-6-yl)-N6-cycloh...)Show SMILES C1CCCC(CC1)Nc1nc(Nc2ccc3ncsc3c2)nc2nc[nH]c12 Show InChI InChI=1S/C19H21N7S/c1-2-4-6-12(5-3-1)23-18-16-17(21-10-20-16)25-19(26-18)24-13-7-8-14-15(9-13)27-11-22-14/h7-12H,1-6H2,(H3,20,21,23,24,25,26) | PDB
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| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research
Curated by ChEMBL
| Assay Description
Inhibition of ATPase activity of human topoisomerase 2 alpha |
Bioorg Med Chem Lett 19: 4014-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.06.034
BindingDB Entry DOI: 10.7270/Q23J3D1M |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50251127
(Bis(2-((2-(7-chloro-6-oxo-6H-dibenzo[cd,g]indazol-...)Show SMILES CN(CCOC(=O)CCCCC(=O)OCCN(C)CCn1nc2-c3cccc(Cl)c3C(=O)c3cccc1c23)CCn1nc2-c3cccc(Cl)c3C(=O)c3cccc1c23 Show InChI InChI=1S/C44H42Cl2N6O6/c1-49(19-21-51-33-15-7-11-29-39(33)41(47-51)27-9-5-13-31(45)37(27)43(29)55)23-25-57-35(53)17-3-4-18-36(54)58-26-24-50(2)20-22-52-34-16-8-12-30-40(34)42(48-52)28-10-6-14-32(46)38(28)44(30)56/h5-16H,3-4,17-26H2,1-2H3 | PDB
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| n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2alpha decantation activity |
Bioorg Med Chem 16: 3959-68 (2008)
Article DOI: 10.1016/j.bmc.2008.01.033
BindingDB Entry DOI: 10.7270/Q2T72H7K |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50221011
(CHEMBL76485)Show SMILES C[C@H]1COc2c(ccc3c2n1cc(C(O)=O)c3=O)N1CC[C@H](C1)C(C)(C)N | PDB
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| n/a | n/a | 8.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter& Gamble Pharmaceuticals
Curated by ChEMBL
| |
Bioorg Med Chem Lett 13: 2373-5 (2003)
|
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50366826
(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)Show SMILES C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c2n1cc(C(O)=O)c3=O |r| Show InChI InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1 | PDB
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| n/a | n/a | 8.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Procter& Gamble Pharmaceuticals
Curated by ChEMBL
| |
Bioorg Med Chem Lett 13: 2373-5 (2003)
|
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50269149
(3alpha,27-dihydroxylup-20(29)-en-28-oic acid methy...)Show SMILES COC(=O)[C@]12CC[C@H]([C@@H]1[C@H]1CC[C@@H]3[C@@]4(C)CC[C@@H](O)C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(CO)CC2)C(C)=C |r| Show InChI InChI=1S/C31H50O4/c1-19(2)20-10-15-30(26(34)35-7)16-17-31(18-32)21(25(20)30)8-9-23-28(5)13-12-24(33)27(3,4)22(28)11-14-29(23,31)6/h20-25,32-33H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24+,25+,28-,29+,30-,31-/m0/s1 | PDB
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| n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Toho University
Curated by ChEMBL
| Assay Description
Inhibition of human topoisomerase 2 |
J Nat Prod 63: 390-2 (2000)
BindingDB Entry DOI: 10.7270/Q2B857WX |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM87351
(Amsacrine hydrochloride | CHEMBL43 | MLS002153376 ...)Show SMILES COc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2ccccc12 Show InChI InChI=1S/C21H19N3O3S/c1-27-20-13-14(24-28(2,25)26)11-12-19(20)23-21-15-7-3-5-9-17(15)22-18-10-6-4-8-16(18)21/h3-13,24H,1-2H3,(H,22,23) | PDB
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| n/a | n/a | 9.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional Autónoma de México
Curated by ChEMBL
| Assay Description
Inhibition of human DNA topoisomerase 2-mediated Crithidia fasciculata kDNA decatenation using ethidium bromide staining by agarose gel electrophores... |
Bioorg Med Chem 17: 3266-77 (2009)
Article DOI: 10.1016/j.bmc.2009.03.052
BindingDB Entry DOI: 10.7270/Q21N811C |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50233985
(CHEMBL4087024)Show SMILES OC1=C(C(c2ccccc2F)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc2C1=O |c:1| | PDB
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| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Universitario de Bio-Org£nica (CIBICAN)
Curated by ChEMBL
| |
Bioorg Med Chem Lett 27: 484-489 (2017)
|
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50233982
(CHEMBL4094724)Show SMILES OC1=C(C(c2ccccc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc2C1=O |c:1| | PDB
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| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Universitario de Bio-Org£nica (CIBICAN)
Curated by ChEMBL
| |
Bioorg Med Chem Lett 27: 484-489 (2017)
|
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50233980
(CHEMBL4065593)Show SMILES OC1=C(C(c2ccc(cc2)[N+]([O-])=O)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc2C1=O |c:1| | PDB
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| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Universitario de Bio-Org£nica (CIBICAN)
Curated by ChEMBL
| |
Bioorg Med Chem Lett 27: 484-489 (2017)
|
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50251129
(7-Chloro-2-{2-[(2-hydroxy-ethyl)-methyl-amino]-eth...)Show InChI InChI=1S/C19H18ClN3O2/c1-22(10-11-24)8-9-23-15-7-3-5-13-17(15)18(21-23)12-4-2-6-14(20)16(12)19(13)25/h2-7,24H,8-11H2,1H3 | PDB
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| Article
PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manitoba
Curated by ChEMBL
| Assay Description
Inhibition of decatenation activity of human topoisomerase 2alpha |
Bioorg Med Chem 17: 4575-82 (2009)
Article DOI: 10.1016/j.bmc.2009.04.072
BindingDB Entry DOI: 10.7270/Q28915XR |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50125944
(CHEMBL3627832)Show InChI InChI=1S/C20H16ClN3OS/c21-12-5-6-14-16(11-12)26-19-17(18(14)25)13-3-1-2-4-15(13)23-20(19)24-9-7-22-8-10-24/h1-6,11,22H,7-10H2 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Taipei Medical University
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant topoisomerase 2 alpha assessed as blocking of supercoiled pHOT DNA relaxation incubated for 45 mins at 37 degC by eth... |
Eur J Med Chem 103: 615-27 (2015)
BindingDB Entry DOI: 10.7270/Q2D79D78 |
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50233984
(CHEMBL4074215)Show SMILES OC1=C(C(c2ccc3OCOc3c2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc2C1=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Universitario de Bio-Org£nica (CIBICAN)
Curated by ChEMBL
| |
Bioorg Med Chem Lett 27: 484-489 (2017)
|
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50233974
(CHEMBL4084514)Show SMILES OC1=C(C(c2ccc(Br)cc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc2C1=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Universitario de Bio-Org£nica (CIBICAN)
Curated by ChEMBL
| |
Bioorg Med Chem Lett 27: 484-489 (2017)
|
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50233978
(CHEMBL4064565)Show SMILES OC1=C(C(c2ccc(Cl)cc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc2C1=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Universitario de Bio-Org£nica (CIBICAN)
Curated by ChEMBL
| |
Bioorg Med Chem Lett 27: 484-489 (2017)
|
More data for this
Ligand-Target Pair | |
DNA topoisomerase II
(Homo sapiens (Human)) | BDBM50233979
(CHEMBL4092257)Show SMILES OC1=C(C(c2ccc(F)cc2)c2c(O)c3ccccc3oc2=O)C(=O)c2ccccc2C1=O |c:1| | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto Universitario de Bio-Org£nica (CIBICAN)
Curated by ChEMBL
| |
Bioorg Med Chem Lett 27: 484-489 (2017)
|
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50377927
(Clerodol | Fagarasterol | Farganasterol | LUPEOL |...)Show SMILES CC(=C)[C@@H]1CC[C@]2(C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12 |r| Show InChI InChI=1S/C30H50O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-25,31H,1,9-18H2,2-8H3/t20-,21+,22-,23+,24-,25+,27+,28-,29+,30+/m0/s1 | PDB
UniProtKB/SwissProt
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| Purchase
KEGG
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Osaka University of Pharmaceutical Sciences
Curated by ChEMBL
| Assay Description
Inhibition of human 1 unit topoisomerase 2alpha catalytic activity assessed as relaxation of 198 ng supercoiled pBR322 DNA by agarose gel electrophor... |
J Nat Prod 64: 1545-7 (2001)
BindingDB Entry DOI: 10.7270/Q2X92C63 |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50208197
(CHEMBL3884560) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Bari"Aldo Moro"
Curated by ChEMBL
| Assay Description
Inhibition of human DNA topoisomerase 2alpha-mediated decatenation of kinetoplast DNA after 60 mins by agarose gel electrophoresis |
Eur J Med Chem 123: 704-717 (2016)
Article DOI: 10.1016/j.ejmech.2016.07.063
BindingDB Entry DOI: 10.7270/Q2TQ63HJ |
More data for this
Ligand-Target Pair | |
Topoisomerase II alpha (HuTopoIIα)
(Homo sapiens (Human)) | BDBM50227946
(9-[[(3-N-methylamino)phenyl]amino]-2-(methylthio)-...)Show InChI InChI=1S/C18H16N4S2/c1-19-11-6-5-7-12(10-11)20-15-13-8-3-4-9-14(13)21-17-16(15)22-18(23-2)24-17/h3-10,19H,1-2H3,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Nacional Autónoma de México
Curated by ChEMBL
| Assay Description
Inhibition of human DNA topoisomerase 2-mediated Crithidia fasciculata kDNA decatenation using ethidium bromide staining by agarose gel electrophores... |
Bioorg Med Chem 17: 3266-77 (2009)
Article DOI: 10.1016/j.bmc.2009.03.052
BindingDB Entry DOI: 10.7270/Q21N811C |
More data for this
Ligand-Target Pair | |
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