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Compile Data Set for Download or QSAR

Found 1 hit of ki for UniProtKB: P11388   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA topoisomerase 2-alpha


(Homo sapiens (Human))		BDBM50357677
PNG
(CHEMBL1914951)
Show SMILES CC(C)(C)Nc1c(nc2ccccn12)-c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C18H19N3O2/c1-18(2,3)20-16-15(19-14-6-4-5-11-21(14)16)12-7-9-13(10-8-12)17(22)23/h4-11,20H,1-3H3,(H,22,23)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 7.50E+4n/an/an/an/an/an/an/an/a



National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL


Assay Description
Competitive inhibition of human topoisomerase-2 alpha-ATPase activity by Lineweaver-Burk assay in presence of 200 to 520 uM ATP

J Med Chem 54: 5013-30 (2011)


Article DOI: 10.1021/jm200235u
BindingDB Entry DOI: 10.7270/Q25T3KW8
More data for this
Ligand-Target Pair