Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50425806 (CHEMBL2316907) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis | J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50425807 (CHEMBL2316902) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis | J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50087856 (CHEMBL3426913) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.20E+3 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Indiana University Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) using pNPP as substrate at pH 7 at 25 degC by spectrophotometric analysis | Bioorg Med Chem 23: 2798-809 (2015) Article DOI: 10.1016/j.bmc.2015.03.066 BindingDB Entry DOI: 10.7270/Q2VD7168 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50607111 (CHEMBL5218807) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01143 BindingDB Entry DOI: 10.7270/Q2BK1HGF | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50054344 (CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University Research and Technology Corporation US Patent | Assay Description For selectivity studies, the PTPs, including LYP, mPTPA, SHP1-D1C, PTP1B, LMPTP, VHR, Laforin and PTPα-D1D2 were expressed and purified from E. ... | US Patent US9522881 (2016) BindingDB Entry DOI: 10.7270/Q2DN4402 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50054344 (CHEMBL3319356 | US9522881, 11a-1 L97M74 | US984453...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) | J Med Chem 57: 6594-609 (2014) Article DOI: 10.1021/jm5006176 BindingDB Entry DOI: 10.7270/Q24X59FM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50425808 (CHEMBL2316906) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis | J Med Chem 56: 832-42 (2013) Article DOI: 10.1021/jm301781p BindingDB Entry DOI: 10.7270/Q2KK9D4X | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50544431 (CHEMBL4637459 | US11192850, Entry 4k) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ... | J Med Chem 63: 9212-9227 (2020) Article DOI: 10.1021/acs.jmedchem.0c00302 BindingDB Entry DOI: 10.7270/Q2QV3R3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50544440 (CHEMBL4647367 | US11192850, Entry 4t) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ... | J Med Chem 63: 9212-9227 (2020) Article DOI: 10.1021/acs.jmedchem.0c00302 BindingDB Entry DOI: 10.7270/Q2QV3R3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50308158 (3-(1-(3-(Biphenyl-4-ylamino)-3-oxopropyl)-1H-1,2,3...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Cdc14A expressed in Escherichia coli assessed as inhibition of p-nitrophenyl phosphate hydrolysis at pH 7 by spectrophotometry | J Med Chem 53: 2482-93 (2010) Article DOI: 10.1021/jm901645u BindingDB Entry DOI: 10.7270/Q2639PVD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50343147 (CHEMBL1773180 | N1-(furan-2-ylmethyl)-N2-(1-(4-(4-...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysis | ACS Med Chem Lett 1: 355-359 (2010) Article DOI: 10.1021/ml1001135 BindingDB Entry DOI: 10.7270/Q26M37TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50343148 (CHEMBL1773181 | N1-(1-(4-(4-fluorophenyl)piperazin...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysis | ACS Med Chem Lett 1: 355-359 (2010) Article DOI: 10.1021/ml1001135 BindingDB Entry DOI: 10.7270/Q26M37TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50544427 (CHEMBL4632818 | US11192850, Entry 4g) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University Curated by ChEMBL | Assay Description Inhibition of CDC14A (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis ... | J Med Chem 63: 9212-9227 (2020) Article DOI: 10.1021/acs.jmedchem.0c00302 BindingDB Entry DOI: 10.7270/Q2QV3R3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50112357 (CHEMBL3609375) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysis | ACS Med Chem Lett 6: 782-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00118 BindingDB Entry DOI: 10.7270/Q2251M0S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50112358 (CHEMBL3609374) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysis | ACS Med Chem Lett 6: 782-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00118 BindingDB Entry DOI: 10.7270/Q2251M0S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50112356 (CHEMBL3609373) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysis | ACS Med Chem Lett 6: 782-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00118 BindingDB Entry DOI: 10.7270/Q2251M0S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50343142 (CHEMBL1773168 | N-(4-butylphenyl)-2-oxo-1,2-dihydr...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysis | ACS Med Chem Lett 1: 355-359 (2010) Article DOI: 10.1021/ml1001135 BindingDB Entry DOI: 10.7270/Q26M37TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558461 (CHEMBL4760367) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50607110 (CHEMBL5219519) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01143 BindingDB Entry DOI: 10.7270/Q2BK1HGF | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558485 (CHEMBL4800195) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558483 (CHEMBL4778085) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558484 (CHEMBL4748824) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558488 (CHEMBL4794972) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01143 BindingDB Entry DOI: 10.7270/Q2BK1HGF | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558486 (CHEMBL4797766) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558487 (CHEMBL4786243) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558488 (CHEMBL4794972) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558482 (CHEMBL4742123) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50558481 (CHEMBL4783639) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of His-tagged CDC14A (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for... | Citation and Details Article DOI: 10.1021/acs.jmedchem.6b00993 BindingDB Entry DOI: 10.7270/Q2DN48Q4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dual specificity protein phosphatase CDC14A (Homo sapiens (Human)) | BDBM50420258 (CEFSULODIN) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of phosphatase activity of human CDC14A using pNPP as a substrate after 10 mins by spectrophotometer analysis | ACS Med Chem Lett 6: 782-6 (2015) Article DOI: 10.1021/acsmedchemlett.5b00118 BindingDB Entry DOI: 10.7270/Q2251M0S | |||||||||||
More data for this Ligand-Target Pair |