Found 318 hits of ic50 data for polymerid = 8409 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594006
(CHEMBL5192839) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594005
(CHEMBL5181947) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594006
(CHEMBL5192839) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594005
(CHEMBL5181947) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594028
(CHEMBL5176874)Show SMILES COc1ccc(NC(=O)c2ccc(NC(=O)N3CCN(CC3)C(=O)c3cc(Cc4n[nH]c(=O)c5ccccc45)ccc3F)cc2)cc1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114417
BindingDB Entry DOI: 10.7270/Q2RB78MX |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594010
(CHEMBL5200358) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594010
(CHEMBL5200358) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594007
(CHEMBL5187187) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594250
(CHEMBL5207717)Show SMILES CC#Cc1ccc2c(nc(CSc3ccc(cc3)C(O)=O)[nH]c2=O)c1C | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 156 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00281
BindingDB Entry DOI: 10.7270/Q26D5Z03 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594011
(CHEMBL5200521) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594007
(CHEMBL5187187) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594011
(CHEMBL5200521) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50468579
(CHEMBL4287262)Show InChI InChI=1S/C14H11NO4/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H2,15,16)(H,17,18) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50468579
(CHEMBL4287262)Show InChI InChI=1S/C14H11NO4/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H2,15,16)(H,17,18) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50452662
(CHEMBL4208737)Show InChI InChI=1S/C14H12FNO2/c15-13-4-2-1-3-11(13)9-18-12-7-5-10(6-8-12)14(16)17/h1-8H,9H2,(H2,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50452662
(CHEMBL4208737)Show InChI InChI=1S/C14H12FNO2/c15-13-4-2-1-3-11(13)9-18-12-7-5-10(6-8-12)14(16)17/h1-8H,9H2,(H2,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 234 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272953
(CHEMBL4128574)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2cccc(F)c2)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-21-5-1-3-19(15-21)17-11-13-28(14-12-17)25(30)20-4-2-6-23(16-20)31-22-9-7-18(8-10-22)24(27)29/h1-10,15-17H,11-14H2,(H2,27,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 245 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272953
(CHEMBL4128574)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2cccc(F)c2)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-21-5-1-3-19(15-21)17-11-13-28(14-12-17)25(30)20-4-2-6-23(16-20)31-22-9-7-18(8-10-22)24(27)29/h1-10,15-17H,11-14H2,(H2,27,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50593992
(CHEMBL5186967) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 288 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50593992
(CHEMBL5186967) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 290 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594008
(CHEMBL5181107) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 309 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50594008
(CHEMBL5181107) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM199181
(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 329 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged PARP10 catalytic domain (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence ba... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM199181
(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) expressed in Escherichia coli Rosetta2 (DE3) using SRPK2 as substrate after 1... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM199181
(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM199181
(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00281
BindingDB Entry DOI: 10.7270/Q26D5Z03 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272959
(CHEMBL4125748)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(O)(CC2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H23FN2O4/c26-20-8-6-19(7-9-20)25(31)12-14-28(15-13-25)24(30)18-2-1-3-22(16-18)32-21-10-4-17(5-11-21)23(27)29/h1-11,16,31H,12-15H2,(H2,27,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 387 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272959
(CHEMBL4125748)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(O)(CC2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H23FN2O4/c26-20-8-6-19(7-9-20)25(31)12-14-28(15-13-25)24(30)18-2-1-3-22(16-18)32-21-10-4-17(5-11-21)23(27)29/h1-11,16,31H,12-15H2,(H2,27,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272966
(CHEMBL4129789)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-21-8-4-17(5-9-21)18-12-14-28(15-13-18)25(30)20-2-1-3-23(16-20)31-22-10-6-19(7-11-22)24(27)29/h1-11,16,18H,12-15H2,(H2,27,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 398 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272966
(CHEMBL4129789)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-21-8-4-17(5-9-21)18-12-14-28(15-13-18)25(30)20-2-1-3-23(16-20)31-22-10-6-19(7-11-22)24(27)29/h1-11,16,18H,12-15H2,(H2,27,29) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272957
(CHEMBL4127497)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCN(CC2)c2ccccc2F)cc1 Show InChI InChI=1S/C24H22FN3O3/c25-21-6-1-2-7-22(21)27-12-14-28(15-13-27)24(30)18-4-3-5-20(16-18)31-19-10-8-17(9-11-19)23(26)29/h1-11,16H,12-15H2,(H2,26,29) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 457 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272957
(CHEMBL4127497)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCN(CC2)c2ccccc2F)cc1 Show InChI InChI=1S/C24H22FN3O3/c25-21-6-1-2-7-22(21)27-12-14-28(15-13-27)24(30)18-4-3-5-20(16-18)31-19-10-8-17(9-11-19)23(26)29/h1-11,16H,12-15H2,(H2,26,29) | PDB
UniProtKB/SwissProt
GoogleScholar
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| PC cid
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UniChem
Similars
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| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272950
(CHEMBL4130035)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCN(CC2)c2cccc(F)c2)cc1 Show InChI InChI=1S/C24H22FN3O3/c25-19-4-2-5-20(16-19)27-11-13-28(14-12-27)24(30)18-3-1-6-22(15-18)31-21-9-7-17(8-10-21)23(26)29/h1-10,15-16H,11-14H2,(H2,26,29) | PDB
UniProtKB/SwissProt
GoogleScholar
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| PC cid
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UniChem
Similars
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PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272961
(CHEMBL4129923)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2F)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-23-7-2-1-6-22(23)17-12-14-28(15-13-17)25(30)19-4-3-5-21(16-19)31-20-10-8-18(9-11-20)24(27)29/h1-11,16-17H,12-15H2,(H2,27,29) | PDB
UniProtKB/SwissProt
GoogleScholar
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| PC cid
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UniChem
Similars
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PubMed
| n/a | n/a | 468 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272950
(CHEMBL4130035)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCN(CC2)c2cccc(F)c2)cc1 Show InChI InChI=1S/C24H22FN3O3/c25-19-4-2-5-20(16-19)27-11-13-28(14-12-27)24(30)18-3-1-6-22(15-18)31-21-9-7-17(8-10-21)23(26)29/h1-10,15-16H,11-14H2,(H2,26,29) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
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UniChem
Similars
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PubMed
| n/a | n/a | 468 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272961
(CHEMBL4129923)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2F)cc1 Show InChI InChI=1S/C25H23FN2O3/c26-23-7-2-1-6-22(23)17-12-14-28(15-13-17)25(30)19-4-3-5-21(16-19)31-20-10-8-18(9-11-20)24(27)29/h1-11,16-17H,12-15H2,(H2,27,29) | PDB
UniProtKB/SwissProt
GoogleScholar
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| PC cid
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Similars
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| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272952
(CHEMBL4126054)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-4-6-11(7-5-9)19-12-3-1-2-10(8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
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| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.2c00281
BindingDB Entry DOI: 10.7270/Q26D5Z03 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272952
(CHEMBL4126054)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-4-6-11(7-5-9)19-12-3-1-2-10(8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272952
(CHEMBL4126054)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-4-6-11(7-5-9)19-12-3-1-2-10(8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 513 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50446130
(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)Show SMILES CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23 Show InChI InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 562 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant human His6-tagged PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50446130
(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)Show SMILES CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23 Show InChI InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
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PubMed
| n/a | n/a | 562 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant human His6-tagged PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50446130
(AG-014699 | AG-14447 | RUCAPARIB CAMSYLATE | Rucap...)Show SMILES CNCc1ccc(cc1)-c1[nH]c2cc(F)cc3C(=O)NCCc1c23 Show InChI InChI=1S/C19H18FN3O/c1-21-10-11-2-4-12(5-3-11)18-14-6-7-22-19(24)15-8-13(20)9-16(23-18)17(14)15/h2-5,8-9,21,23H,6-7,10H2,1H3,(H,22,24) | PDB
UniProtKB/SwissProt
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| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Health& Science University
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant human His6-tagged PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
J Med Chem 60: 1262-1271 (2017)
Article DOI: 10.1021/acs.jmedchem.6b00990
BindingDB Entry DOI: 10.7270/Q28054VV |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272965
(CHEMBL4127327)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H24N2O3/c26-24(28)20-9-11-22(12-10-20)30-23-8-4-7-21(17-23)25(29)27-15-13-19(14-16-27)18-5-2-1-3-6-18/h1-12,17,19H,13-16H2,(H2,26,28) | PDB
UniProtKB/SwissProt
GoogleScholar
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| PC cid
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| n/a | n/a | 575 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272965
(CHEMBL4127327)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCC(CC2)c2ccccc2)cc1 Show InChI InChI=1S/C25H24N2O3/c26-24(28)20-9-11-22(12-10-20)30-23-8-4-7-21(17-23)25(29)27-15-13-19(14-16-27)18-5-2-1-3-6-18/h1-12,17,19H,13-16H2,(H2,26,28) | PDB
UniProtKB/SwissProt
GoogleScholar
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| PC cid
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UniChem
Similars
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PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50593991
(CHEMBL5206305) | PDB
UniProtKB/SwissProt
GoogleScholar
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| PC cid
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| n/a | n/a | 589 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50593991
(CHEMBL5206305) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM199181
(4-[(4-Carbamoylcyclohexyl)oxy]cyclohexane-1-carbox...)Show InChI InChI=1S/C14H12N2O3/c15-13(17)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(16)18/h1-8H,(H2,15,17)(H2,16,18) | PDB
UniProtKB/SwissProt
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| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oulu
Curated by ChEMBL
| Assay Description
Inhibition of C-terminal His-tagged human ARTD10 (809 to 1017 residues) R931A mutant expressed in Escherichia coli Rosetta2 (DE3) Rosetta2 (DE3) usin... |
Eur J Med Chem 156: 93-102 (2018)
Article DOI: 10.1016/j.ejmech.2018.06.047
BindingDB Entry DOI: 10.7270/Q2P271SW |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50593993
(CHEMBL5198692) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50272954
(CHEMBL4128256)Show SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCCC(C2)c2ccccc2)cc1 Show InChI InChI=1S/C25H24N2O3/c26-24(28)19-11-13-22(14-12-19)30-23-10-4-8-20(16-23)25(29)27-15-5-9-21(17-27)18-6-2-1-3-7-18/h1-4,6-8,10-14,16,21H,5,9,15,17H2,(H2,26,28) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
McDaniel College
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla... |
Bioorg Med Chem Lett 28: 2050-2054 (2018)
Article DOI: 10.1016/j.bmcl.2018.04.056
BindingDB Entry DOI: 10.7270/Q2RR21R2 |
More data for this
Ligand-Target Pair | |
Protein mono-ADP-ribosyltransferase PARP10
(Homo sapiens (Human)) | BDBM50593993
(CHEMBL5198692) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 603 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114362
BindingDB Entry DOI: 10.7270/Q20V8HSS |
More data for this
Ligand-Target Pair | |
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