BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 947 hits of affinity data for UniProtKB/TrEMBL: P06870   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kallikrein-1 (KLK1)


(Homo sapiens (Human))
BDBM50034582
PNG
(CHEMBL2448441 | Peptide boronate)
Show SMILES Br.[H][C@@]12CC3CC(C3(C)C)[C@]1(C)OB(O2)C(CCC\C(S)=N\N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |TLB:11:10:7:5,THB:12:10:7:5,14:2:7:5|
Show InChI InChI=1S/C37H50BN5O6S.BrH/c1-36(2)26-21-29(36)37(3)30(22-26)48-38(49-37)31(17-10-18-32(50)42-39)41-33(44)28-16-11-19-43(28)34(45)27(20-24-12-6-4-7-13-24)40-35(46)47-23-25-14-8-5-9-15-25;/h4-9,12-15,26-31H,10-11,16-23,39H2,1-3H3,(H,40,46)(H,41,44)(H,42,50);1H/t26?,27-,28-,29?,30+,31?,37-;/m0./s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
0.00490n/an/an/an/an/an/an/an/a



Thrombosis Research Institute

Curated by ChEMBL


Assay Description
Binding affinity against kallikrein


J Med Chem 38: 1511-22 (1995)

More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 151-a
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.160n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 110-a
PNG
((Z)-5-(3-Chloro-2,6-difluorophenyl)-2-(15-chloro-2...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.210n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 114-a
PNG
((Z)-5-(3-chloro-2,6-difluorophenyl)-2-(24-((methox...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.240n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 112-a
PNG
((Z)-5-(3-Chloro-2,6-difluorophenyl)-2-(15-ethyl-24...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.260n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 6-a
PNG
(5-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)-2-(24-((me...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.290n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 145-a
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.300n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 71
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.330n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 111-a
PNG
((Z)-5-(3-chloro-2,6-difluorophenyl)-2-(24-((methox...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.340n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 37
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.360n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 143-b
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.400n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 102-a
PNG
((Z)-5-(5-Chloro-2-(difluoromethoxy)phenyl)-2-(24-(...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.430n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 125
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.430n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 45
PNG
((S)-2-(24-(((2-(tert-butoxy)ethoxy)carbonyl)amino)...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.440n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 81-a
PNG
(9-(5-(5-chloro-2-(1h-tetrazol-1-yl)phenyl)-1-oxido...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.460n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 98-a
PNG
((Z)-5-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)-2-(24-...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.490n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 150-a
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.510n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 76-a
PNG
(5-(3-chloro-2,6-difluorophenyl)-2-((5R,9S)-15-fluo...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.530n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 3-d
PNG
(5-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)-2-((5R,9S)...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.590n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 96-a
PNG
((Z)-5-(3-chloro-2,6-difluorophenyl)-2-(24-((methox...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.600n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 117
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.650n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 130
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.660n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 35
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.700n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 146-a
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.710n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 124
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.730n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 128
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.740n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 109-a
PNG
((Z)-5-(3-chloro-2,6-difluorophenyl)-2-(24-((ethoxy...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.770n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 114-c
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.780n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 120
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.780n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 39
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.810n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 36-a
PNG
(5-(5-chloro-2-(4-(difluoromethyl)-1H-1,2,3-triazol...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.810n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 38
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
0.950n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 108-a
PNG
((Z)-2-(24-Amino-4-OXO-11H-3-aza-1(4,2)-imidazola-2...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.02n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 100-a
PNG
((Z)-5-(3-Chloro-6-(difluoromethoxy)-2-fluorophenyl...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.02n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 73
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.08n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 145-c
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.10n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 99-a
PNG
((Z)-5-(5-chloro-2-(trifluoromethoxy)phenyl)-2-(24-...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.21n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 86-a
PNG
(5-(3-Chloro-2,6-difluorophenyl)-2-(16-fluoro-24-((...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.29n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 144
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.35n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 161
PNG
((Z)-5-(3-chloro-2-fluoro-6-(1H-tetrazol-1-yl)pheny...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.35n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 166-a
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.39n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 123
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.41n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 52
PNG
(5-(5-chloro-2-(1h-tetrazol-1-yl)phenyl)-2-(15-fluo...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.43n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 76-b
PNG
(5-(3-chloro-2,6-difluorophenyl)-2-((5S,9S)-15-fluo...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.5n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 150-c
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.5n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 46
PNG
((S)-5-(3-chloro-2,6-difluorophenyl)-2-(24-(((2-hyd...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.53n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 13-a
PNG
(5-(3-Chloro-2,6-difluorophenyl)-2-(24-((methoxycar...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.55n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 28
PNG
(methyl (9-(5-(3-chloro-2- fluoro-6-(1h-tetrazol-1-...)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.57n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 143-a
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.61n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Kallikrein 1


(Homo sapiens (Human))
US10214512, Example 33
PNG
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
UniChem
Article
1.67n/an/an/an/an/an/an/an/a



GSK





J Med Chem 50: 4453-70 (2007)


Article DOI: 10.1021/jm0611051
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 947 total )  |  Next  |  Last  >>
Jump to: