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Compile Data Set for Download or QSAR

Found 1144 hits of kd for UniProtKB: P61964   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164773
PNG
(CHEMBL3799127)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(N)cc1
Show InChI InChI=1S/C24H24F3N5O2/c1-31-8-10-32(11-9-31)21-7-4-16(15-2-5-17(28)6-3-15)12-20(21)30-23(34)18-14-29-22(33)13-19(18)24(25,26)27/h2-7,12-14H,8-11,28H2,1H3,(H,29,33)(H,30,34)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164785
PNG
(CHEMBL3797967)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnn(CCN2CCOCC2)c1
Show InChI InChI=1S/C27H32F3N7O3/c1-34-4-7-36(8-5-34)24-3-2-19(20-16-32-37(18-20)9-6-35-10-12-40-13-11-35)14-23(24)33-26(39)21-17-31-25(38)15-22(21)27(28,29)30/h2-3,14-18H,4-13H2,1H3,(H,31,38)(H,33,39)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428271
PNG
(CHEMBL2337032)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)[N+]([O-])=O
Show InChI InChI=1S/C19H20ClFN4O3/c1-12-15(21)5-4-14(18(12)20)19(26)22-16-11-13(25(27)28)3-6-17(16)24-9-7-23(2)8-10-24/h3-6,11H,7-10H2,1-2H3,(H,22,26)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164786
PNG
(CHEMBL3798573)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(C)c1)-c1cnc2ccccc2c1
Show InChI InChI=1S/C28H28N4O/c1-20-6-5-8-23(16-20)28(33)30-26-18-21(10-11-27(26)32-14-12-31(2)13-15-32)24-17-22-7-3-4-9-25(22)29-19-24/h3-11,16-19H,12-15H2,1-2H3,(H,30,33)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164788
PNG
(CHEMBL3800271)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(C)cc(C)c1)[N+]([O-])=O
Show InChI InChI=1S/C20H24N4O3/c1-14-10-15(2)12-16(11-14)20(25)21-18-13-17(24(26)27)4-5-19(18)23-8-6-22(3)7-9-23/h4-5,10-13H,6-9H2,1-3H3,(H,21,25)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164789
PNG
(CHEMBL3798578)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(C)c(F)c(C)c1)[N+]([O-])=O
Show InChI InChI=1S/C20H23FN4O3/c1-13-10-15(11-14(2)19(13)21)20(26)22-17-12-16(25(27)28)4-5-18(17)24-8-6-23(3)7-9-24/h4-5,10-12H,6-9H2,1-3H3,(H,22,26)
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n/an/an/a 330n/an/an/an/an/a



Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164790
PNG
(CHEMBL3797611)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c(F)c(C)c(F)c(C)c1F)[N+]([O-])=O
Show InChI InChI=1S/C20H21F3N4O3/c1-11-17(21)12(2)19(23)16(18(11)22)20(28)24-14-10-13(27(29)30)4-5-15(14)26-8-6-25(3)7-9-26/h4-5,10H,6-9H2,1-3H3,(H,24,28)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164791
PNG
(CHEMBL3799704)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)[N+]([O-])=O
Show InChI InChI=1S/C18H18F3N5O4/c1-24-4-6-25(7-5-24)15-3-2-11(26(29)30)8-14(15)23-17(28)12-10-22-16(27)9-13(12)18(19,20)21/h2-3,8-10H,4-7H2,1H3,(H,22,27)(H,23,28)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164792
PNG
(CHEMBL3798198)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc2OCCc2c1
Show InChI InChI=1S/C26H25F3N4O3/c1-32-7-9-33(10-8-32)22-4-2-17(16-3-5-23-18(12-16)6-11-36-23)13-21(22)31-25(35)19-15-30-24(34)14-20(19)26(27,28)29/h2-5,12-15H,6-11H2,1H3,(H,30,34)(H,31,35)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164770
PNG
(CHEMBL3799275)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cnc2ccccc2c1
Show InChI InChI=1S/C27H24F3N5O2/c1-34-8-10-35(11-9-34)24-7-6-17(19-12-18-4-2-3-5-22(18)31-15-19)13-23(24)33-26(37)20-16-32-25(36)14-21(20)27(28,29)30/h2-7,12-16H,8-11H2,1H3,(H,32,36)(H,33,37)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164793
PNG
(CHEMBL3799840)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc2[nH]ccc2c1
Show InChI InChI=1S/C26H24F3N5O2/c1-33-8-10-34(11-9-33)23-5-3-17(16-2-4-21-18(12-16)6-7-30-21)13-22(23)32-25(36)19-15-31-24(35)14-20(19)26(27,28)29/h2-7,12-15,30H,8-11H2,1H3,(H,31,35)(H,32,36)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164794
PNG
(CHEMBL3798846 | US11174250, Example Table4.1.1 | U...)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cccc(CN2CCOCC2)c1
Show InChI InChI=1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15-18H,7-14,19H2,1H3,(H,33,38)(H,34,39)
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n/an/an/a 30n/an/an/an/an/a



Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164795
PNG
(CHEMBL3799608)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(NC(C)=O)nc1
Show InChI InChI=1S/C25H25F3N6O3/c1-15(35)31-22-6-4-17(13-29-22)16-3-5-21(34-9-7-33(2)8-10-34)20(11-16)32-24(37)18-14-30-23(36)12-19(18)25(26,27)28/h3-6,11-14H,7-10H2,1-2H3,(H,30,36)(H,32,37)(H,29,31,35)
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n/an/an/a 30n/an/an/an/an/a



Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164796
PNG
(CHEMBL3800054)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1ccc(N)nc1
Show InChI InChI=1S/C23H23F3N6O2/c1-31-6-8-32(9-7-31)19-4-2-14(15-3-5-20(27)28-12-15)10-18(19)30-22(34)16-13-29-21(33)11-17(16)23(24,25)26/h2-5,10-13H,6-9H2,1H3,(H2,27,28)(H,29,33)(H,30,34)
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Ontario Institute for Cancer Research

Curated by ChEMBL


Assay Description
Binding affinity to human poly His-tagged WDR5 (1 to 334 residues) expressed in Escherichia coli BL21(DE3)-V2R-pRARE2 cells by surface plasmon resona...

J Med Chem 59: 2478-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01630
BindingDB Entry DOI: 10.7270/Q2VT1V0C
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50184787
PNG
(CHEMBL3823308)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)c(C)c1Cl)-c1ccncc1
Show InChI InChI=1S/C24H24ClFN4O/c1-16-20(26)5-4-19(23(16)25)24(31)28-21-15-18(17-7-9-27-10-8-17)3-6-22(21)30-13-11-29(2)12-14-30/h3-10,15H,11-14H2,1-2H3,(H,28,31)
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n/an/an/a 133n/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged human WDR5 expressed in Escherichia coli by isothermal titration calorimetry

Eur J Med Chem 118: 1-8 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.032
BindingDB Entry DOI: 10.7270/Q26H4KBP
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50184789
PNG
(CHEMBL3822691)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cc(c(F)c(C)c1Cl)[N+]([O-])=O)[N+]([O-])=O
Show InChI InChI=1S/C19H19ClFN5O5/c1-11-17(20)13(10-16(18(11)21)26(30)31)19(27)22-14-9-12(25(28)29)3-4-15(14)24-7-5-23(2)6-8-24/h3-4,9-10H,5-8H2,1-2H3,(H,22,27)
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n/an/an/a 343n/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged human WDR5 expressed in Escherichia coli by isothermal titration calorimetry

Eur J Med Chem 118: 1-8 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.032
BindingDB Entry DOI: 10.7270/Q26H4KBP
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50164794
PNG
(CHEMBL3798846 | US11174250, Example Table4.1.1 | U...)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1c[nH]c(=O)cc1C(F)(F)F)-c1cccc(CN2CCOCC2)c1
Show InChI InChI=1S/C29H32F3N5O3/c1-35-7-9-37(10-8-35)26-6-5-22(21-4-2-3-20(15-21)19-36-11-13-40-14-12-36)16-25(26)34-28(39)23-18-33-27(38)17-24(23)29(30,31)32/h2-6,15-18H,7-14,19H2,1H3,(H,33,38)(H,34,39)
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n/an/an/a 93n/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Binding affinity to His-tagged human WDR5 expressed in Escherichia coli BL21 by isothermal titration calorimetry

Eur J Med Chem 118: 1-8 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.032
BindingDB Entry DOI: 10.7270/Q26H4KBP
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50195371
PNG
(CHEMBL3906778)
Show SMILES COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cccc(OC)c2)c1
Show InChI InChI=1S/C21H25N3O4/c1-23-9-11-24(12-10-23)19-8-7-16(21(26)28-3)14-18(19)22-20(25)15-5-4-6-17(13-15)27-2/h4-8,13-14H,9-12H2,1-3H3,(H,22,25)
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n/an/an/a 3.00E+3n/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of N-terminal FITC-GSARAEVHLRKS binding to WDR5 (unknown origin) by fluorescence polarization assay

Bioorg Med Chem 24: 6109-6118 (2016)


Article DOI: 10.1016/j.bmc.2016.09.073
BindingDB Entry DOI: 10.7270/Q2F47R4K
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428235
PNG
(CHEMBL2337028)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccc(F)cc1)[N+]([O-])=O
Show InChI InChI=1S/C18H19FN4O3/c1-21-8-10-22(11-9-21)17-7-6-15(23(25)26)12-16(17)20-18(24)13-2-4-14(19)5-3-13/h2-7,12H,8-11H2,1H3,(H,20,24)
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n/an/an/a 3.10E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428236
PNG
(CHEMBL1457864)
Show SMILES COc1cccc(c1)C(=O)Nc1cc(ccc1N1CCN(C)CC1)[N+]([O-])=O
Show InChI InChI=1S/C19H22N4O4/c1-21-8-10-22(11-9-21)18-7-6-15(23(25)26)13-17(18)20-19(24)14-4-3-5-16(12-14)27-2/h3-7,12-13H,8-11H2,1-2H3,(H,20,24)
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n/an/an/a 1.40E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428237
PNG
(CHEMBL2337450)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(O)c1)[N+]([O-])=O
Show InChI InChI=1S/C18H20N4O4/c1-20-7-9-21(10-8-20)17-6-5-14(22(25)26)12-16(17)19-18(24)13-3-2-4-15(23)11-13/h2-6,11-12,23H,7-10H2,1H3,(H,19,24)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428238
PNG
(CHEMBL2337449)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(C)c1Cl)[N+]([O-])=O
Show InChI InChI=1S/C19H21ClN4O3/c1-13-4-3-5-15(18(13)20)19(25)21-16-12-14(24(26)27)6-7-17(16)23-10-8-22(2)9-11-23/h3-7,12H,8-11H2,1-2H3,(H,21,25)
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n/an/an/a 1.10E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428239
PNG
(CHEMBL2337448)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(C)c1)[N+]([O-])=O
Show InChI InChI=1S/C19H22N4O3/c1-14-4-3-5-15(12-14)19(24)20-17-13-16(23(25)26)6-7-18(17)22-10-8-21(2)9-11-22/h3-7,12-13H,8-11H2,1-2H3,(H,20,24)
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n/an/an/a 1.10E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428240
PNG
(CHEMBL2337447)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccc(Cl)c1)[N+]([O-])=O
Show InChI InChI=1S/C18H19ClN4O3/c1-21-7-9-22(10-8-21)17-6-5-15(23(25)26)12-16(17)20-18(24)13-3-2-4-14(19)11-13/h2-6,11-12H,7-10H2,1H3,(H,20,24)
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n/an/an/a 1.80E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428241
PNG
(CHEMBL2337446)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(C)=O)[N+]([O-])=O
Show InChI InChI=1S/C13H18N4O3/c1-10(18)14-12-9-11(17(19)20)3-4-13(12)16-7-5-15(2)6-8-16/h3-4,9H,5-8H2,1-2H3,(H,14,18)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428242
PNG
(CHEMBL2337445)
Show SMILES CN(C)CCN(C)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C18H21ClN4O3/c1-21(2)10-11-22(3)17-9-8-13(23(25)26)12-16(17)20-18(24)14-6-4-5-7-15(14)19/h4-9,12H,10-11H2,1-3H3,(H,20,24)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428243
PNG
(CHEMBL2337444)
Show SMILES NC1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C18H19ClN4O3/c19-15-4-2-1-3-14(15)18(24)21-16-11-13(23(25)26)5-6-17(16)22-9-7-12(20)8-10-22/h1-6,11-12H,7-10,20H2,(H,21,24)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428244
PNG
(CHEMBL2337443)
Show SMILES NC1CCN(C1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C17H17ClN4O3/c18-14-4-2-1-3-13(14)17(23)20-15-9-12(22(24)25)5-6-16(15)21-8-7-11(19)10-21/h1-6,9,11H,7-8,10,19H2,(H,20,23)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428245
PNG
(CHEMBL2337442)
Show SMILES [O-][N+](=O)c1ccc(N2CCNCC2)c(NC(=O)c2ccccc2Cl)c1
Show InChI InChI=1S/C17H17ClN4O3/c18-14-4-2-1-3-13(14)17(23)20-15-11-12(22(24)25)5-6-16(15)21-9-7-19-8-10-21/h1-6,11,19H,7-10H2,(H,20,23)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428246
PNG
(CHEMBL2337441)
Show SMILES CN(C)C1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C20H23ClN4O3/c1-23(2)14-9-11-24(12-10-14)19-8-7-15(25(27)28)13-18(19)22-20(26)16-5-3-4-6-17(16)21/h3-8,13-14H,9-12H2,1-2H3,(H,22,26)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428247
PNG
(CHEMBL2337039)
Show SMILES CN(C)C1CCN(C1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C19H21ClN4O3/c1-22(2)14-9-10-23(12-14)18-8-7-13(24(26)27)11-17(18)21-19(25)15-5-3-4-6-16(15)20/h3-8,11,14H,9-10,12H2,1-2H3,(H,21,25)
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n/an/an/a 1.58E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428248
PNG
(CHEMBL2337038)
Show SMILES CCN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C19H21ClN4O3/c1-2-22-9-11-23(12-10-22)18-8-7-14(24(26)27)13-17(18)21-19(25)15-5-3-4-6-16(15)20/h3-8,13H,2,9-12H2,1H3,(H,21,25)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428249
PNG
(CHEMBL2337037)
Show SMILES [O-][N+](=O)c1ccc(N2CCCCC2)c(NC(=O)c2ccccc2Cl)c1
Show InChI InChI=1S/C18H18ClN3O3/c19-15-7-3-2-6-14(15)18(23)20-16-12-13(22(24)25)8-9-17(16)21-10-4-1-5-11-21/h2-3,6-9,12H,1,4-5,10-11H2,(H,20,23)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428250
PNG
(CHEMBL2337036)
Show SMILES [O-][N+](=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccccc2Cl)c1
Show InChI InChI=1S/C17H16ClN3O4/c18-14-4-2-1-3-13(14)17(22)19-15-11-12(21(23)24)5-6-16(15)20-7-9-25-10-8-20/h1-6,11H,7-10H2,(H,19,22)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428251
PNG
(CHEMBL2337035)
Show SMILES CN1CCCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C19H21ClN4O3/c1-22-9-4-10-23(12-11-22)18-8-7-14(24(26)27)13-17(18)21-19(25)15-5-2-3-6-16(15)20/h2-3,5-8,13H,4,9-12H2,1H3,(H,21,25)
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n/an/an/a 7.00E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428252
PNG
(CHEMBL2337034)
Show SMILES CC1CN(CCN1C)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C19H21ClN4O3/c1-13-12-23(10-9-22(13)2)18-8-7-14(24(26)27)11-17(18)21-19(25)15-5-3-4-6-16(15)20/h3-8,11,13H,9-10,12H2,1-2H3,(H,21,25)
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n/an/an/a 4.70E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428253
PNG
(CHEMBL2337033)
Show SMILES [O-][N+](=O)c1ccc(F)c(NC(=O)c2ccccc2Cl)c1
Show InChI InChI=1S/C13H8ClFN2O3/c14-10-4-2-1-3-9(10)13(18)16-12-7-8(17(19)20)5-6-11(12)15/h1-7H,(H,16,18)
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n/an/an/a>2.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428254
PNG
(CHEMBL1609857)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C18H19ClN4O3/c1-21-8-10-22(11-9-21)17-7-6-13(23(25)26)12-16(17)20-18(24)14-4-2-3-5-15(14)19/h2-7,12H,8-11H2,1H3,(H,20,24)
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n/an/an/a 6.90E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428254
PNG
(CHEMBL1609857)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)[N+]([O-])=O
Show InChI InChI=1S/C18H19ClN4O3/c1-21-8-10-22(11-9-21)17-7-6-13(23(25)26)12-16(17)20-18(24)14-4-2-3-5-15(14)19/h2-7,12H,8-11H2,1H3,(H,20,24)
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n/an/an/a 7.00E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of MLL-WIN N-terminal FITC-tagged GSARAEVHLRKS peptide from human WDR5 (1-334) by fluorescence polarization assay

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428256
PNG
(CHEMBL2337027)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)-c1ccncc1
Show InChI InChI=1S/C23H23ClN4O/c1-27-12-14-28(15-13-27)22-7-6-18(17-8-10-25-11-9-17)16-21(22)26-23(29)19-4-2-3-5-20(19)24/h2-11,16H,12-15H2,1H3,(H,26,29)
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n/an/an/a 2.20E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428257
PNG
(CHEMBL2337026)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)-c1ccco1
Show InChI InChI=1S/C22H22ClN3O2/c1-25-10-12-26(13-11-25)20-9-8-16(21-7-4-14-28-21)15-19(20)24-22(27)17-5-2-3-6-18(17)23/h2-9,14-15H,10-13H2,1H3,(H,24,27)
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n/an/an/a 3.50E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428258
PNG
(CHEMBL2337025)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)C1CC1
Show InChI InChI=1S/C21H24ClN3O/c1-24-10-12-25(13-11-24)20-9-8-16(15-6-7-15)14-19(20)23-21(26)17-4-2-3-5-18(17)22/h2-5,8-9,14-15H,6-7,10-13H2,1H3,(H,23,26)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428259
PNG
(CHEMBL2331612)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)C(O)=O
Show InChI InChI=1S/C19H20ClN3O3/c1-22-8-10-23(11-9-22)17-7-6-13(19(25)26)12-16(17)21-18(24)14-4-2-3-5-15(14)20/h2-7,12H,8-11H2,1H3,(H,21,24)(H,25,26)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428260
PNG
(CHEMBL2337024)
Show SMILES CN1CCN(CC1)c1ccc(N)cc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C18H21ClN4O/c1-22-8-10-23(11-9-22)17-7-6-13(20)12-16(17)21-18(24)14-4-2-3-5-15(14)19/h2-7,12H,8-11,20H2,1H3,(H,21,24)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428261
PNG
(CHEMBL2337023)
Show SMILES CN1CCN(CC1)c1ccc(Br)cc1NC(=O)c1ccccc1Cl
Show InChI InChI=1S/C18H19BrClN3O/c1-22-8-10-23(11-9-22)17-7-6-13(19)12-16(17)21-18(24)14-4-2-3-5-15(14)20/h2-7,12H,8-11H2,1H3,(H,21,24)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428262
PNG
(CHEMBL2337022)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccccc1Cl)C(F)(F)F
Show InChI InChI=1S/C19H19ClF3N3O/c1-25-8-10-26(11-9-25)17-7-6-13(19(21,22)23)12-16(17)24-18(27)14-4-2-3-5-15(14)20/h2-7,12H,8-11H2,1H3,(H,24,27)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428263
PNG
(CHEMBL2337021)
Show SMILES COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccccc2Cl)c1
Show InChI InChI=1S/C20H22ClN3O3/c1-23-9-11-24(12-10-23)18-8-7-14(20(26)27-2)13-17(18)22-19(25)15-5-3-4-6-16(15)21/h3-8,13H,9-12H2,1-2H3,(H,22,25)
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n/an/an/a 6.60E+3n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428264
PNG
(CHEMBL1559278)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1ccco1)[N+]([O-])=O
Show InChI InChI=1S/C16H18N4O4/c1-18-6-8-19(9-7-18)14-5-4-12(20(22)23)11-13(14)17-16(21)15-3-2-10-24-15/h2-5,10-11H,6-9H2,1H3,(H,17,21)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428265
PNG
(CHEMBL2337020)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)c1cccnc1)[N+]([O-])=O
Show InChI InChI=1S/C17H19N5O3/c1-20-7-9-21(10-8-20)16-5-4-14(22(24)25)11-15(16)19-17(23)13-3-2-6-18-12-13/h2-6,11-12H,7-10H2,1H3,(H,19,23)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
WD repeat-containing protein 5


(Homo sapiens (Human))		BDBM50428266
PNG
(CHEMBL2337019)
Show SMILES CN1CCN(CC1)c1ccc(cc1NC(=O)Cc1ccccc1)[N+]([O-])=O
Show InChI InChI=1S/C19H22N4O3/c1-21-9-11-22(12-10-21)18-8-7-16(23(25)26)14-17(18)20-19(24)13-15-5-3-2-4-6-15/h2-8,14H,9-13H2,1H3,(H,20,24)
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n/an/an/a>1.00E+4n/an/an/an/an/a



EntreMed Inc.

Curated by ChEMBL


Assay Description
Displacement of N-terminal isothiocyanate-fluorescein-labeled H3(ARTKQTARKSTGGKA) peptide from human WDR5 expressed in Escherichia coli BL21(DE3) by ...

ACS Med Chem Lett 4: 353-7 (2013)


Article DOI: 10.1021/ml300467n
BindingDB Entry DOI: 10.7270/Q2C53N6F
More data for this
Ligand-Target Pair
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