Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272095 (4-(3-(4-methoxyphenyl)-1H-indol-2-yl)benzenesulfon...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.00603 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272131 (3-(4-fluorophenyl)-2-(4-(methylsulfonyl)phenyl)-1H...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272096 (3-(4-methoxyphenyl)-2-(4-(methylsulfonyl)phenyl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272129 (4-(5-methyl-3-phenyl-1H-indol-2-yl)benzenesulfonam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272125 (4-(3-p-tolyl-1H-indol-2-yl)benzenesulfonamide | CH...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.0692 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272126 (2-(4-(methylsulfonyl)phenyl)-3-p-tolyl-1H-indole |...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.0891 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272105 (4-(3-phenyl-1H-indol-2-yl)benzenesulfonamide | CHE...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.0891 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272110 (4-(5-chloro-3-phenyl-1H-indol-2-yl)benzenesulfonam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.141 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272097 (3-(3,4-dimethylphenyl)-2-(4-(methylsulfonyl)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272128 (CHEMBL500943 | N-(4-(3-phenyl-1H-indol-2-yl)phenyl...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.178 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272130 (5-methyl-2-(4-(methylsulfonyl)phenyl)-3-phenyl-1H-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.282 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272111 (5-chloro-2-(4-(methylsulfonyl)phenyl)-3-phenyl-1H-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.363 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272124 (3-(4-bromophenyl)-2-(4-(methylsulfonyl)phenyl)-1H-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.372 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a | n/a |
Peking University Health Science Center Curated by ChEMBL | Assay Description Inhibition of LPS-induced COX2 activity in C57BL/6J mouse peritoneal macrophages by RIA | J Nat Prod 69: 1591-5 (2006) Article DOI: 10.1021/np060287z BindingDB Entry DOI: 10.7270/Q2VM4C13 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272090 (4-(5-chloro-3-(4-chlorophenyl)-1H-indol-2-yl)benze...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.537 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094551 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094551 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.601 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272106 (2-(4-(methylsulfonyl)phenyl)-3-phenyl-1H-indole | ...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.603 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094542 (1,3-Diphenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094542 (1,3-Diphenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrro...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.701 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272092 (5-chloro-3-(3-chlorophenyl)-2-(4-(methylsulfonyl)p...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 0.794 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094539 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094539 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50566911 (CHEMBL4868446) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In vivo inhibition of COX2 in po dosed C57BL/6J mouse model of spontaneous GI-tract tumor Apc-min assessed as chemopreventive effect by measuring red... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00890 BindingDB Entry DOI: 10.7270/Q24B352D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272113 (5-bromo-2-(4-(methylsulfonyl)phenyl)-3-phenyl-1H-i...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272127 (4-(3-(3,4-dimethylphenyl)-1H-indol-2-yl)benzenesul...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094540 (1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole | CHE...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094540 (1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole | CHE...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094546 (3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094546 (3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094563 (1,3-Di-p-tolyl-4,5,6,7-tetrahydro-2H-isoindole | 1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.67 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094534 (1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094534 (1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094532 (1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-ylamine...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094532 (1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-ylamine...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50566912 (CHEMBL4859571) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description In vivo inhibition of COX2 in po dosed C57BL/6J mouse model of spontaneous GI-tract tumor Apc-min assessed as chemopreventive effect by measuring red... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00890 BindingDB Entry DOI: 10.7270/Q24B352D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50272109 (4-(5-fluoro-3-phenyl-1H-indol-2-yl)benzenesulfonam...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of COX2 in Mus musculus (mouse) peritoneal macrophage | Citation and Details Article DOI: 10.1007/s00044-008-9117-0 BindingDB Entry DOI: 10.7270/Q25T3PBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50029593 (CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | <2 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University Curated by ChEMBL | Assay Description Inhibitory activity against murine Prostaglandin G/H synthase 2. | Bioorg Med Chem Lett 14: 2559-62 (2004) Article DOI: 10.1016/j.bmcl.2004.02.099 BindingDB Entry DOI: 10.7270/Q2VD7005 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50173289 (2-Fluoro-4-(5-methyl-3-phenyl-isoxazol-4-yl)-benze...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
David Geffen School of Medicine at University of California Curated by ChEMBL | Assay Description Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophages | Bioorg Med Chem Lett 15: 4699-702 (2005) Article DOI: 10.1016/j.bmcl.2005.07.065 BindingDB Entry DOI: 10.7270/Q2H131KS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50173288 (4-(5-Fluoromethyl-3-phenyl-isoxazol-4-yl)-benzenes...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
David Geffen School of Medicine at University of California Curated by ChEMBL | Assay Description Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophages | Bioorg Med Chem Lett 15: 4699-702 (2005) Article DOI: 10.1016/j.bmcl.2005.07.065 BindingDB Entry DOI: 10.7270/Q2H131KS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50173290 (4-[5-(2-Fluoro-ethyl)-3-phenyl-isoxazol-4-yl]-benz...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
David Geffen School of Medicine at University of California Curated by ChEMBL | Assay Description Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophages | Bioorg Med Chem Lett 15: 4699-702 (2005) Article DOI: 10.1016/j.bmcl.2005.07.065 BindingDB Entry DOI: 10.7270/Q2H131KS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50173287 (4-[3-(4-Fluoro-phenyl)-5-methyl-isoxazol-4-yl]-ben...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
David Geffen School of Medicine at University of California Curated by ChEMBL | Assay Description Tested for prostaglandin E2 production as a function of COX-2 inhibition using endotoxin-treated murine RAW 264.7 macrophages | Bioorg Med Chem Lett 15: 4699-702 (2005) Article DOI: 10.1016/j.bmcl.2005.07.065 BindingDB Entry DOI: 10.7270/Q2H131KS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50492037 (CHEMBL2391055) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Sapienza Curated by ChEMBL | Assay Description Inhibition of COX2 in mouse J774 cells assessed as inhibition of LPS-induced PGE2 production by radioimmunoassay | Bioorg Med Chem 21: 3695-701 (2013) Article DOI: 10.1016/j.bmc.2013.04.031 BindingDB Entry DOI: 10.7270/Q2GT5R3K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50361590 (CHEMBL1939677) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£"Sapienza" Curated by ChEMBL | Assay Description Inhibition of COX-2-mediated PGE2 production in LPS-stimulated mouse J774 cells after 24 hrs by radioimmunoassay | J Med Chem 54: 7759-71 (2011) Article DOI: 10.1021/jm200715n BindingDB Entry DOI: 10.7270/Q2W37WR0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094558 (3,5-Diphenyl-4-aza-tricyclo[5.2.1.0*2,6*]deca-2,5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094558 (3,5-Diphenyl-4-aza-tricyclo[5.2.1.0*2,6*]deca-2,5-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094548 (1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherche Servier Curated by ChEMBL | Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages | J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094548 (1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50589579 (CHEMBL5185981) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.ejmech.2022.114615 BindingDB Entry DOI: 10.7270/Q2ZK5MMK | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Mus musculus (Mouse)) | BDBM50094528 (5,6-Dimethyl-1,3-diphenyl-4,5,6,7-tetrahydro-2H-is...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Dr HS Gour University Curated by ChEMBL | Assay Description Inhibition of mouse macrophage COX2 | Eur J Med Chem 43: 1559-69 (2008) Article DOI: 10.1016/j.ejmech.2007.09.028 BindingDB Entry DOI: 10.7270/Q2M909WP | |||||||||||
More data for this Ligand-Target Pair |
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