Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: Q13523   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase PRP4 homolog (Homo sapiens (Human))	BDBM213236 (4-ylmethyl)-carbamoyl]-thiophen-2-yl}-benzo[b]thio...) Show SMILES NC(=O)c1cc2c(cccc2s1)-c1ccc(s1)C(=O)NCc1ccnc(Cl)c1 Show InChI InChI=1S/C20H16ClN3O3S2/c21-18-8-11(6-7-23-18)10-24-19(25)15-5-4-14(28-15)12-2-1-3-16-13(12)9-17(20(26)27)29(16)22/h1-9,29H,10,22H2,(H,24,25)(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	7.5	25
Sanofi Oncology					Assay Description The PRP4 phosphorylation reaction was performed at room temperature with 15 nM full-length His-tagged PAK4 recombinant protein expressed in Escherich...				J Biol Chem 288: 30125-38 (2013) Article DOI: 10.1074/jbc.M113.473348 BindingDB Entry DOI: 10.7270/Q26D5RTC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase PRP4 homolog (Homo sapiens (Human))	BDBM50585189 (CHEMBL5083125) Show SMILES NS(=O)(=O)c1ccc(CNc2nc(Nc3cccc(CN4CCOCC4)c3)ncc2Br)cc1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human PRP4 (663 to end residues) using casein as substrate incubated for 120 mins in presence of [gamma-33P-ATP] by radiome...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00440 BindingDB Entry DOI: 10.7270/Q27S7SND
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PRP4 homolog (Homo sapiens (Human))	BDBM50519662 (CHEMBL4438748) Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1 Show InChI InChI=1S/C26H23N3O5/c1-29(2)20-8-6-17(7-9-20)26(32)28-19-5-3-4-18(14-19)27-25(31)16-34-21-10-11-22-23(30)12-13-33-24(22)15-21/h3-15H,16H2,1-2H3,(H,27,31)(H,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human PRP4 (663 to end residues) using casein as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometri...				J Med Chem 62: 10691-10710 (2019) Article DOI: 10.1021/acs.jmedchem.9b01143 BindingDB Entry DOI: 10.7270/Q2MC93FG
					More data for this Ligand-Target Pair