Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50000999 (CHEBI:81724 | DIMINAZENE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Xavier University of Louisiana Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells | Bioorg Med Chem 22: 1983-92 (2014) Article DOI: 10.1016/j.bmc.2014.02.049 BindingDB Entry DOI: 10.7270/Q2N29ZGG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50207159 (2-aminoguanidine | 2-azanylguanidine | AMINOGUANID...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | Article | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281515 ((E)-3-(1H-Imidazol-4-yl)-allylamine | CHEMBL119195...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281515 ((E)-3-(1H-Imidazol-4-yl)-allylamine | CHEMBL119195...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM45440 (4-[5-(4-amidinophenoxy)pentoxy]benzamidine;2-hydro...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Xavier University of Louisiana Curated by ChEMBL | Assay Description Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells | Bioorg Med Chem 22: 1983-92 (2014) Article DOI: 10.1016/j.bmc.2014.02.049 BindingDB Entry DOI: 10.7270/Q2N29ZGG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281517 (3-(1H-Imidazol-4-yl)-prop-2-ynylamine | CHEMBL1165...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50020274 (2,2-Difluoro-hex-5-yne-1,4-diamonium; dichloride |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merrell Dow Research Institute Curated by ChEMBL | Assay Description In vitro inhibition against hog kidney diamine oxidase | J Med Chem 32: 170-3 (1989) BindingDB Entry DOI: 10.7270/Q2DB80TK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121458 (1-[3-(2-Hydroxy-phenyl)-5-o-tolyl-4,5-dihydro-pyra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50281518 (2-(1H-Imidazol-4-yl)-allylamine | CHEMBL116538) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article | 7.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for ability of the compound to competitively inhibit hog kidney diamine oxidase (DAO) in a spectrometric assay | Bioorg Med Chem Lett 3: 353-356 (1993) Article DOI: 10.1016/S0960-894X(01)80909-4 BindingDB Entry DOI: 10.7270/Q24749ST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121455 (1-[3-(2-Hydroxy-phenyl)-5-m-tolyl-4,5-dihydro-pyra...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121457 (1-[3-(2,4-Dihydroxy-phenyl)-5-m-tolyl-4,5-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amiloride-sensitive amine oxidase [copper-containing] (Homo sapiens (Human)) | BDBM50121456 (1-[3-(2,4-Dihydroxy-phenyl)-5-o-tolyl-4,5-dihydro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Roma La Sapienza Curated by ChEMBL | Assay Description Inhibitory activity of the compound against Swine kidney diamine oxidase (SKDAO) | Bioorg Med Chem Lett 12: 3629-33 (2002) BindingDB Entry DOI: 10.7270/Q22B8XD8 | |||||||||||
More data for this Ligand-Target Pair |