Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human)) | BDBM228800 (NOEV | Sapienic acid (SpA)) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 940 | -8.55 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human)) | BDBM50163440 ((2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 4.90E+4 | -6.11 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human)) | BDBM228802 (5N,6S-(N'-butyliminomethylidene)-6-thio-1-deox...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | 5.33E+4 | -6.06 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human)) | BDBM228803 (5N,6S-(N'-butyliminomethylidene)-6-thiogalacto...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.20E+5 | -4.96 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human)) | BDBM228804 (N-(N'-butylthiocarbamoyl)-1-deoxygalactonojiri...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.88E+5 | -4.84 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase [24-677,R201C] (Homo sapiens (Human)) | BDBM228805 (Galactose) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | 5.61E+6 | -3.19 | n/a | n/a | n/a | n/a | n/a | 4.5 | 37 |
The University of Tokyo | Assay Description β-Gal activity was measured by using 4-methylumbelliferyll-β-D-galactopyranoside in buffer B (0.15 M sodium citrate, pH 4.5, and 0.2 M NaCl... | J Biol Chem 289: 14560-8 (2014) Article DOI: 10.1074/jbc.M113.529529 BindingDB Entry DOI: 10.7270/Q2WH2NW4 | |||||||||||
More data for this Ligand-Target Pair |