Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50391000 (CB-01-11 | RIFAMYCIN) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck & Co., Inc. | Assay Description Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t... | ACS Chem Biol 12: 1346-1352 (2017) Article DOI: 10.1021/acschembio.6b01133 BindingDB Entry DOI: 10.7270/Q2VM4B41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50391000 (CB-01-11 | RIFAMYCIN) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck & Co., Inc. | Assay Description Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t... | ACS Chem Biol 12: 1346-1352 (2017) Article DOI: 10.1021/acschembio.6b01133 BindingDB Entry DOI: 10.7270/Q2VM4B41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592137 (US11572337, Compound 0MTK149) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592141 (US11572337, Compound 0MTK158) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592173 (US11572337, Compound 0MTK267) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592161 (US11572337, Compound 0MTK237) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50155485 (CHEMBL184023 | Myxopyronin B | methyl (E)-5-(5-((2...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli | Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592133 (US11572337, Compound 0MTK127) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592145 (US11572337, Compound 0MTK176) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 390 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592132 (US11572337, Compound 0MTK107) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592142 (US11572337, Compound 0MTK174) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592138 (US11572337, Compound 0MTK154) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592144 (US11572337, Compound 0MTK175) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592146 (US11572337, Compound 0MTK178) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592164 (US11572337, Compound 0MTK256) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592135 (US11572337, Compound 0MTK146) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 690 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592175 (US11572337, Compound 0MTK269) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592159 (US11572337, Compound 0MTK232) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592162 (US11572337, Compound 0MTK238) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592166 (US11572337, Compound 0MTK260) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592139 (US11572337, Compound 0MTK155) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592136 (US11572337, Compound 0MTK148) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592174 (US11572337, Compound 0MTK268) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592165 (US11572337, Compound 0MTK257) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592170 (US11572337, Compound 0MTK264) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592140 (US11572337, Compound 0MTK156) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592147 (US11572337, Compound 0MTK180) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50155484 (CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli | Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592134 (US11572337, Compound 0MTK128) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 970 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50155487 (CHEMBL185900 | {(E)-5-[4-Hydroxy-5-((2E,4E)-2-meth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli | Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592172 (US11572337, Compound 0MTK266) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50155484 (CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli | Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592169 (US11572337, Compound 0MTK263) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592171 (US11572337, Compound 0MTK265) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592148 (US11572337, Compound 0MTK181) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592168 (US11572337, Compound 0MTK262) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592167 (US11572337, Compound 0MTK261) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592149 (US11572337, Compound 0MTK183) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM228835 (MRL-436) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck & Co., Inc. | Assay Description Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t... | ACS Chem Biol 12: 1346-1352 (2017) Article DOI: 10.1021/acschembio.6b01133 BindingDB Entry DOI: 10.7270/Q2VM4B41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592163 (US11572337, Compound 0MTK240) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50155484 (CHEMBL185761 | CHEMBL186013 | CHEMBL186014 | {(E)-...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli | Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit alpha/beta/beta'/omega (Escherichia coli K-12) | BDBM50000054 (CHEMBL3228735) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Escherichia coli DNA-dependent RNA polymerase | J Med Chem 22: 1051-5 (1979) BindingDB Entry DOI: 10.7270/Q2SQ91WG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM228835 (MRL-436) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | 37 |
Merck & Co., Inc. | Assay Description Fluorescence-detected RNAP inhibition assays in Tables 1 and 4 were performed using a DNA fragment containing the lacUV5 promoter as a template and t... | ACS Chem Biol 12: 1346-1352 (2017) Article DOI: 10.1021/acschembio.6b01133 BindingDB Entry DOI: 10.7270/Q2VM4B41 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592176 (US11572337, Compound 3RKHTK161) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50155483 (CHEMBL185927 | {5-[5-((2E,4E)-2,5-Dimethyl-nona-2,...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli | Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM50155489 (CHEMBL185050 | {(E)-5-[5-((2E,4E)-2,5-Dimethyl-non...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Anadys Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against RNA polymerase of Escherichia coli | Bioorg Med Chem Lett 14: 5667-72 (2004) Article DOI: 10.1016/j.bmcl.2004.08.045 BindingDB Entry DOI: 10.7270/Q2C53KBD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592160 (US11572337, Compound 0MTK233) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592155 (US11572337, Compound 0MTK223) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592154 (US11572337, Compound 0MTK222) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592150 (US11572337, Compound 0MTK204) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair |
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