Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120943 (US8716296, 89) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.00500 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120941 (US8716296, 82) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0150 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120934 (US8716296, 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0180 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120936 (US8716296, 5 | US8716296, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0190 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120942 (US8716296, 83) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0290 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120935 (US8716296, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0390 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120939 (US8716296, 52) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.116 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120936 (US8716296, 5 | US8716296, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.173 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM126500 (US11591322, Compound NVP-2 | US8778951, 310) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | <0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02190 BindingDB Entry DOI: 10.7270/Q2BV7MPD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM126500 (US11591322, Compound NVP-2 | US8778951, 310) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | n/a | n/a | <0.514 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Effective concentration required for inhibitory activity towards human beta-1 adrenergic receptor | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM444516 (US10662186, Compound 38 | US10988476, Compound I-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. US Patent | Assay Description 1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100... | US Patent US10662186 (2020) BindingDB Entry DOI: 10.7270/Q2GX4FKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM444516 (US10662186, Compound 38 | US10988476, Compound I-3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.920 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. US Patent | Assay Description 1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100... | US Patent US10988476 (2021) BindingDB Entry DOI: 10.7270/Q2PR8047 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50139171 (Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK9 (unknown origin) expressed in Sf9 insect cells using biotinylated peptide derived Histone H1 as substrate incubated for 1 hr in pr... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01148 BindingDB Entry DOI: 10.7270/Q2154MVT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180827 (US9133171, 32) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50193093 (RGB-286638) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02190 BindingDB Entry DOI: 10.7270/Q2BV7MPD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120940 (US8716296, 53) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.08 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM167699 (US9073922, 186 | US9796708, Example 186) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate by TR-FRET LANCE method | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00744 BindingDB Entry DOI: 10.7270/Q2FB56K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM167699 (US9073922, 186 | US9796708, Example 186) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Blocking activity against Beta-1 adrenergic receptor in spontaneously beating guinea pig atrial preparations | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM120938 (US8716296, 51) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.25 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Ingenium Pharmaceuticals GmbH US Patent | Assay Description All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt... | US Patent US8716296 (2014) BindingDB Entry DOI: 10.7270/Q2PN949G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM25036 (CHEMBL393525 | N'-[(1E)-{6-bromoimidazo[1,2-a]pyri...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nebraska Medical Center Curated by ChEMBL | Assay Description Inhibition of CDK9 (unknown origin) | J Med Chem 59: 8667-8684 (2016) Article DOI: 10.1021/acs.jmedchem.6b00150 BindingDB Entry DOI: 10.7270/Q2G73GP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50193104 (CHEMBL3905910) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve. | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50263013 (CHEMBL4079206) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of human CDK9 | Bioorg Med Chem 27: 677-685 (2019) Article DOI: 10.1016/j.bmc.2019.01.027 BindingDB Entry DOI: 10.7270/Q2CF9TG4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50600028 (CHEMBL5190816) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02190 BindingDB Entry DOI: 10.7270/Q2BV7MPD | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180837 (US9133171, 42) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180836 (US9133171, 41) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180824 (US9133171, 29 | US9133171, 30 | US9133171, 31) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180819 (US9133171, 24) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180843 (US9133171, 48) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50363196 (CHEMBL1944698) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human CDK9 | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00744 BindingDB Entry DOI: 10.7270/Q2FB56K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180799 (US9133171, 13 | US9133171, 14 | US9133171, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180823 (US9133171, 28) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180824 (US9133171, 29 | US9133171, 30 | US9133171, 31) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180824 (US9133171, 29 | US9133171, 30 | US9133171, 31) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180851 (US9133171, 56) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180853 (US9133171, 58) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM167858 (US9073922, 355) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie, Inc. US Patent | Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in... | US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM167859 (US9073922, 356) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie, Inc. US Patent | Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in... | US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM167860 (US9073922, 357) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie, Inc. US Patent | Assay Description CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in... | US Patent US9073922 (2015) BindingDB Entry DOI: 10.7270/Q2CJ8C78 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM180815 (US9133171, 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 8.0 | 22 |
Bayer Intellectual Property GmbH US Patent | Assay Description Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchased fro... | US Patent US9133171 (2015) BindingDB Entry DOI: 10.7270/Q2SX6C0W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM444542 (US10662186, Compound 62 | US10988476, Compound I-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.44 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. US Patent | Assay Description 1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100... | US Patent US10988476 (2021) BindingDB Entry DOI: 10.7270/Q2PR8047 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM444542 (US10662186, Compound 62 | US10988476, Compound I-6...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.44 | n/a | n/a | n/a | n/a | n/a | n/a |
SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. US Patent | Assay Description 1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100... | US Patent US10662186 (2020) BindingDB Entry DOI: 10.7270/Q2GX4FKS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50186373 (CHEMBL424696 | N-(5-(2-(cyclohexyloxy)pyrimidin-4-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute Curated by ChEMBL | Assay Description Inhibition of CDK9 | Bioorg Med Chem Lett 16: 3751-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.048 BindingDB Entry DOI: 10.7270/Q2N29WK0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM354126 (US9796708, Example 1358 | trans-4-{4-[5-fluoro-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK9 (unknown origin) using Ulight-labeled substrate by TR-FRET LANCE method | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00744 BindingDB Entry DOI: 10.7270/Q2FB56K3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM354126 (US9796708, Example 1358 | trans-4-{4-[5-fluoro-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Blocking activity against Beta-2 adrenergic receptor in guinea pig tracheal strips | Citation and Details | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM50528817 (CHEMBL4462530 | US10717746, Example 14 | US2023041...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM454533 (US10717746, Example 16) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM454535 (US10717746, Example 18) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM454536 (US10717746, Example 19) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM454536 (US10717746, Example 19) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM454537 (US10717746, Example 20) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | <3 | n/a | n/a | n/a | n/a | n/a | n/a |
ASTRAZENECA AB US Patent | Assay Description Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o... | US Patent US10717746 (2020) BindingDB Entry DOI: 10.7270/Q2NV9N9F | |||||||||||
More data for this Ligand-Target Pair |
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