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Compile Data Set for Download or QSAR

Found 21 hits of ic50 for UniProtKB: P01120   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233136
PNG
(Arteminolide C')
Show SMILES C\C=C(\C)C(=O)O[C@H]1C[C@H](C)[C@H]2[C@@H]([C@H]3OC(=O)C4(CC56C=C[C@]4(C)C5[C@H]4OC(=O)C(=C)[C@@H]4CC[C@@]6(C)O)[C@H]13)C(C)=CC2=O |r,c:20,45,TLB:37:17:24:20.21,THB:15:17:24:20.21,25:24:18.17:20.21|
Show InChI InChI=1S/C35H42O8/c1-8-16(2)29(37)41-22-14-18(4)23-21(36)13-17(3)24(23)27-25(22)35(31(39)43-27)15-34-12-11-32(35,6)28(34)26-20(9-10-33(34,7)40)19(5)30(38)42-26/h8,11-13,18,20,22-28,40H,5,9-10,14-15H2,1-4,6-7H3/b16-8-/t18-,20-,22-,23+,24-,25+,26-,27+,28?,32+,33+,34?,35?/m0/s1
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n/an/a 950n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233137
PNG
(Arteminolide C)
Show SMILES C\C=C(\C)C(=O)O[C@H]1C[C@H](C)[C@H]2[C@@H]([C@H]3OC(=O)C4(CC56C=C[C@]4(C)C5[C@H]4OC(=O)C(C)[C@@H]4CC[C@@]6(C)O)[C@H]13)C(C)=CC2=O |r,c:20,45,TLB:37:17:24:20.21,THB:15:17:24:20.21,25:24:18.17:20.21|
Show InChI InChI=1S/C35H44O8/c1-8-16(2)29(37)41-22-14-18(4)23-21(36)13-17(3)24(23)27-25(22)35(31(39)43-27)15-34-12-11-32(35,6)28(34)26-20(9-10-33(34,7)40)19(5)30(38)42-26/h8,11-13,18-20,22-28,40H,9-10,14-15H2,1-7H3/b16-8-/t18-,19?,20-,22-,23+,24-,25+,26-,27+,28?,32+,33+,34?,35?/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233135
PNG
(6-O-angeloylprenolin)
Show SMILES C\C=C(\C)C(=O)O[C@H]1[C@@H]2[C@@H](C[C@@H](C)[C@@H]3C=CC(=O)[C@@]13C)OC(=O)[C@H]2C |r,c:14|
Show InChI InChI=1S/C20H26O5/c1-6-10(2)18(22)25-17-16-12(4)19(23)24-14(16)9-11(3)13-7-8-15(21)20(13,17)5/h6-8,11-14,16-17H,9H2,1-5H3/b10-6-/t11-,12+,13+,14-,16+,17+,20+/m1/s1
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n/an/a 1.88E+4n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233132
PNG
(Acetyl-11β,13-dihydro-4-epi-isoxanthanol (15))
Show SMILES CC(CC(OC(C)=O)C1=CC[C@H]2[C@H](C[C@@H]1C)OC(=O)[C@@H]2C)OC(C)=O |r,t:8|
Show InChI InChI=1S/C19H28O6/c1-10-8-17-16(12(3)19(22)25-17)7-6-15(10)18(24-14(5)21)9-11(2)23-13(4)20/h6,10-12,16-18H,7-9H2,1-5H3/t10-,11?,12+,16+,17-,18?/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233123
PNG
(Acetyl-4-epi-isoxanthanol (6))
Show SMILES CC(CC(OC(C)=O)C1=CC[C@H]2[C@H](C[C@@H]1C)OC(=O)C2=C)OC(C)=O |r,t:8|
Show InChI InChI=1S/C19H26O6/c1-10-8-17-16(12(3)19(22)25-17)7-6-15(10)18(24-14(5)21)9-11(2)23-13(4)20/h6,10-11,16-18H,3,7-9H2,1-2,4-5H3/t10-,11?,16+,17-,18?/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233134
PNG
(8-Epi-xanthatin-1,5α-epoxide)
Show SMILES C[C@H]1C[C@H]2OC(=O)C(=C)[C@H]2C[C@H]2O[C@@]12\C=C\C(C)=O |r|
Show InChI InChI=1S/C15H18O4/c1-8-6-12-11(10(3)14(17)18-12)7-13-15(8,19-13)5-4-9(2)16/h4-5,8,11-13H,3,6-7H2,1-2H3/b5-4+/t8-,11+,12+,13+,15-/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233133
PNG
(8-Epi-xanthatin)
Show SMILES C[C@H]1C[C@H]2OC(=O)C(=C)[C@H]2CC=C1\C=C\C(C)=O |r,c:12|
Show InChI InChI=1S/C15H18O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h4-6,9,13-14H,3,7-8H2,1-2H3/b5-4+/t9-,13+,14+/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233129
PNG
(11β,13-Dihydroxanthatin-1,5β-epoxide (12...)
Show SMILES C[C@@H]1[C@H]2C[C@@H]3O[C@]3(\C=C\C(C)=O)[C@@H](C)C[C@@H]2OC1=O |r|
Show InChI InChI=1S/C15H20O4/c1-8-6-12-11(10(3)14(17)18-12)7-13-15(8,19-13)5-4-9(2)16/h4-5,8,10-13H,6-7H2,1-3H3/b5-4+/t8-,10+,11+,12-,13-,15+/m0/s1
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n/an/a 6.60E+4n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233128
PNG
(11β,13-Dihydroxanthatin-1,5α-epoxide (11...)
Show SMILES C[C@@H]1[C@H]2C[C@H]3O[C@@]3(\C=C\C(C)=O)[C@@H](C)C[C@@H]2OC1=O |r|
Show InChI InChI=1S/C15H20O4/c1-8-6-12-11(10(3)14(17)18-12)7-13-15(8,19-13)5-4-9(2)16/h4-5,8,10-13H,6-7H2,1-3H3/b5-4+/t8-,10+,11+,12-,13+,15-/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233121
PNG
(Xanthatin-1,5α-epoxide (5))
Show SMILES C[C@H]1C[C@@H]2OC(=O)C(=C)[C@H]2C[C@H]2O[C@@]12\C=C\C(C)=O |r|
Show InChI InChI=1S/C15H18O4/c1-8-6-12-11(10(3)14(17)18-12)7-13-15(8,19-13)5-4-9(2)16/h4-5,8,11-13H,3,6-7H2,1-2H3/b5-4+/t8-,11+,12-,13+,15-/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233119
PNG
(Xanthatin (2))
Show SMILES C[C@H]1C[C@@H]2OC(=O)C(=C)[C@H]2CC=C1\C=C\C(C)=O |r,c:12|
Show InChI InChI=1S/C15H18O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h4-6,9,13-14H,3,7-8H2,1-2H3/b5-4+/t9-,13+,14-/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233118
PNG
(α-Methylene-γ-lactone, 1)
Show SMILES C[C@H]1C[C@@H]2OC(=O)C(=C)[C@H]2CC=C1C(CC(C)=O)OC(C)=O |r,c:12|
Show InChI InChI=1S/C17H22O5/c1-9-7-15-14(11(3)17(20)22-15)6-5-13(9)16(8-10(2)18)21-12(4)19/h5,9,14-16H,3,6-8H2,1-2,4H3/t9-,14+,15-,16?/m0/s1
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n/an/a 1.50E+5n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233127
PNG
(11β,13-Dihydroxanthatin (10))
Show SMILES C[C@@H]1[C@H]2CC=C(\C=C\C(C)=O)[C@@H](C)C[C@@H]2OC1=O |r,t:4|
Show InChI InChI=1S/C15H20O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h4-6,9,11,13-14H,7-8H2,1-3H3/b5-4+/t9-,11+,13+,14-/m0/s1
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n/an/a 2.10E+5n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233130
PNG
(11,13-Dihydroxanthinosin (13))
Show SMILES CC1[C@H]2CC=C(CCC(C)=O)[C@@H](C)C[C@@H]2OC1=O |r,w:1.0,t:4|
Show InChI InChI=1S/C15H22O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h6,9,11,13-14H,4-5,7-8H2,1-3H3/t9-,11?,13+,14-/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233120
PNG
(Xanthatin-1,5β-epoxide (4))
Show SMILES C[C@H]1C[C@@H]2OC(=O)C(=C)[C@H]2C[C@@H]2O[C@]12\C=C\C(C)=O |r|
Show InChI InChI=1S/C15H18O4/c1-8-6-12-11(10(3)14(17)18-12)7-13-15(8,19-13)5-4-9(2)16/h4-5,8,11-13H,3,6-7H2,1-2H3/b5-4+/t8-,11+,12-,13-,15+/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233126
PNG
(11β,13-Dihydro-4-epi-isoxanthanol (16))
Show SMILES CC(O)CC(OC(C)=O)C1=CC[C@H]2[C@H](C[C@@H]1C)OC(=O)[C@@H]2C |r,t:9|
Show InChI InChI=1S/C17H26O5/c1-9-7-15-14(11(3)17(20)22-15)6-5-13(9)16(8-10(2)18)21-12(4)19/h5,9-11,14-16,18H,6-8H2,1-4H3/t9-,10?,11+,14+,15-,16?/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233131
PNG
(2,3-(E)-Dehydro-4-epi-isoxanthanol (9))
Show SMILES CC(OC(C)=O)\C=C\C1=CC[C@H]2[C@H](C[C@@H]1C)OC(=O)[C@@H]2C |r,w:1.1,t:8|
Show InChI InChI=1S/C17H24O4/c1-10-9-16-15(12(3)17(19)21-16)8-7-14(10)6-5-11(2)20-13(4)18/h5-7,10-12,15-16H,8-9H2,1-4H3/b6-5+/t10-,11?,12+,15+,16-/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233117
PNG
(α-Methylene-γ-lactone, 3)
Show SMILES CC(O)CC(OC(C)=O)C1=CC[C@H]2[C@H](C[C@@H]1C)OC(=O)C2=C |r,t:9|
Show InChI InChI=1S/C17H24O5/c1-9-7-15-14(11(3)17(20)22-15)6-5-13(9)16(8-10(2)18)21-12(4)19/h5,9-10,14-16,18H,3,6-8H2,1-2,4H3/t9-,10?,14+,15-,16?/m0/s1
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UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233122
PNG
(3,5-Oxyxanthatin (7))
Show SMILES C[C@H]1C[C@@H]2OC(=O)C(=C)[C@H]2Cc2oc(cc12)C(C)=O |r|
Show InChI InChI=1S/C15H16O4/c1-7-4-13-11(8(2)15(17)19-13)6-14-10(7)5-12(18-14)9(3)16/h5,7,11,13H,2,4,6H2,1,3H3/t7-,11+,13-/m0/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+6n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233125
PNG
(4,11,13-Tetrahydroxanthinosin (14))
Show SMILES CC(O)CCC1=CC[C@H]2[C@H](C[C@@H]1C)OC(=O)C2C |r,w:16.18,1.1,t:5|
Show InChI InChI=1S/C15H24O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h6,9-11,13-14,16H,4-5,7-8H2,1-3H3/t9-,10?,11?,13+,14-/m0/s1
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+6n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair
Ras-like protein 2


(Saccharomyces cerevisiae (Baker's yeast))
BDBM233124
PNG
(4,11β,13-Tetrahydroxanthatin (8))
Show SMILES CC(O)\C=C\C1=CC[C@H]2[C@H](C[C@@H]1C)OC(=O)[C@@H]2C |r,w:1.1,t:5|
Show InChI InChI=1S/C15H22O3/c1-9-8-14-13(11(3)15(17)18-14)7-6-12(9)5-4-10(2)16/h4-6,9-11,13-14,16H,7-8H2,1-3H3/b5-4+/t9-,10?,11+,13+,14-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+6n/an/an/an/a7.530



UFR des Sciences Pharmaceutiques et Ingénierie de la Santé



Assay Description
Assays were realized on 96-well plates, prepared with Biomek NKMC and Biomek 3000 from Beckman Coulter and read on a Wallac Victor fluorimeter from P...


J Enzyme Inhib Med Chem 25: 172-9 (2010)


Article DOI: 10.3109/14756360903169592
BindingDB Entry DOI: 10.7270/Q2JS9PBP
More data for this
Ligand-Target Pair