Compile Data Set for Download or QSAR

Found 72 hits of ic50 data for complexid = 50000285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) Show SMILES CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCCCCCCCCCCN Show InChI InChI=1S/C25H43N3O3/c1-2-13-24(30)28-23(20-21-14-16-22(29)17-15-21)25(31)27-19-12-10-8-6-4-3-5-7-9-11-18-26/h14-17,23,29H,2-13,18-20,26H2,1H3,(H,27,31)(H,28,30)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473035 (CHEMBL342483) Show SMILES CCCC(=O)N[C@@H](Cc1cccc(O)c1)C(=O)NCCCCCCCCCCCCN Show InChI InChI=1S/C25H43N3O3/c1-2-14-24(30)28-23(20-21-15-13-16-22(29)19-21)25(31)27-18-12-10-8-6-4-3-5-7-9-11-17-26/h13,15-16,19,23,29H,2-12,14,17-18,20,26H2,1H3,(H,27,31)(H,28,30)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473033 (CHEMBL342258) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C27H45N3O5/c28-13-7-17-34-15-4-5-16-35-18-8-14-29-27(33)25(20-23-11-6-12-24(31)19-23)30-26(32)21-22-9-2-1-3-10-22/h6,11-12,19,22,25,31H,1-5,7-10,13-18,20-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473023 (CHEMBL342235) Show SMILES NCCCNCCCCNCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C27H47N5O3/c28-13-7-16-29-14-4-5-15-30-17-8-18-31-27(35)25(20-23-11-6-12-24(33)19-23)32-26(34)21-22-9-2-1-3-10-22/h6,11-12,19,22,25,29-30,33H,1-5,7-10,13-18,20-21,28H2,(H,31,35)(H,32,34)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473029 (CHEMBL140056) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C27H45N3O5/c28-14-6-18-34-16-4-5-17-35-19-7-15-29-27(33)25(20-23-10-12-24(31)13-11-23)30-26(32)21-22-8-2-1-3-9-22/h10-13,22,25,31H,1-9,14-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322520 ((2S,3S)-2-Biphenyl-4-yl-3,5,5-trimethylmorpholin-2...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C19H23NO2/c1-14-19(21,22-13-18(2,3)20-14)17-11-9-16(10-12-17)15-7-5-4-6-8-15/h4-12,14,20-21H,13H2,1-3H3/t14-,19+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322515 ((2S,3S)-2-(Naphthalen-1-yl)-3,5,5-trimethylmorphol...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(c1)-c1cccc2ccccc12 |r| Show InChI InChI=1S/C23H25NO2/c1-16-23(25,26-15-22(2,3)24-16)19-11-6-10-18(14-19)21-13-7-9-17-8-4-5-12-20(17)21/h4-14,16,24-25H,15H2,1-3H3/t16-,23+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322516 ((+/-)2-(3,5-Dichlorophenyl)-3,5,5-trimethylmorphol...) Show SMILES CC1NC(C)(C)COC1(O)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C13H17Cl2NO2/c1-8-13(17,18-7-12(2,3)16-8)9-4-10(14)6-11(15)5-9/h4-6,8,16-17H,7H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322518 ((+/-)2-(3,4-Dichlorophenyl)-3,5,5-trimethylmorphol...) Show SMILES CC1NC(C)(C)COC1(O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C13H17Cl2NO2/c1-8-13(17,18-7-12(2,3)16-8)9-4-5-10(14)11(15)6-9/h4-6,8,16-17H,7H2,1-3H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322532 ((2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3/t9-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50048392 (2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...) Show SMILES CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C13H18ClNO/c1-9(15-13(2,3)4)12(16)10-6-5-7-11(14)8-10/h5-9,15H,1-4H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473036 (CHEMBL141037) Show SMILES NCCCCCCCCCCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C29H43N3O3/c30-19-12-7-5-3-1-2-4-6-8-13-20-31-29(35)27(22-25-17-14-18-26(33)21-25)32-28(34)23-24-15-10-9-11-16-24/h9-11,14-18,21,27,33H,1-8,12-13,19-20,22-23,30H2,(H,31,35)(H,32,34)/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322512 ((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...) Show SMILES CCC[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C15H22ClNO2/c1-4-6-13-15(18,19-10-14(2,3)17-13)11-7-5-8-12(16)9-11/h5,7-9,13,17-18H,4,6,10H2,1-3H3/t13-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50210332 (CHEMBL3889475) Show SMILES [H][C@]1(CCOC)C[C@]1([H])c1cncc(c1)N1CCCN(C)CC1 |r| Show InChI InChI=1S/C17H27N3O/c1-19-5-3-6-20(8-7-19)16-10-15(12-18-13-16)17-11-14(17)4-9-21-2/h10,12-14,17H,3-9,11H2,1-2H3/t14-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...				Eur J Med Chem 124: 689-697 (2016) Article DOI: 10.1016/j.ejmech.2016.09.016 BindingDB Entry DOI: 10.7270/Q2H41TDB
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50210334 (CHEMBL3948977) Show SMILES [H][C@]1(CCOC)C[C@]1([H])c1cncc(c1)N1CCCNCC1 |r| Show InChI InChI=1S/C16H25N3O/c1-20-8-3-13-10-16(13)14-9-15(12-18-11-14)19-6-2-4-17-5-7-19/h9,11-13,16-17H,2-8,10H2,1H3/t13-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...				Eur J Med Chem 124: 689-697 (2016) Article DOI: 10.1016/j.ejmech.2016.09.016 BindingDB Entry DOI: 10.7270/Q2H41TDB
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50210336 (CHEMBL3899499) Show SMILES [H][C@@]1(CCOC)C[C@@]1([H])c1cncc(c1)N1C[C@]2([H])C[C@@]1([H])CN2 |r| Show InChI InChI=1S/C16H23N3O/c1-20-3-2-11-5-16(11)12-4-14(8-17-7-12)19-10-13-6-15(19)9-18-13/h4,7-8,11,13,15-16,18H,2-3,5-6,9-10H2,1H3/t11-,13+,15+,16-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...				Eur J Med Chem 124: 689-697 (2016) Article DOI: 10.1016/j.ejmech.2016.09.016 BindingDB Entry DOI: 10.7270/Q2H41TDB
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50210337 (CHEMBL3970672) Show SMILES OCCc1cc(on1)-c1cncc(c1)N1CCCNCC1 Show InChI InChI=1S/C15H20N4O2/c20-7-2-13-9-15(21-18-13)12-8-14(11-17-10-12)19-5-1-3-16-4-6-19/h8-11,16,20H,1-7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...				Eur J Med Chem 124: 689-697 (2016) Article DOI: 10.1016/j.ejmech.2016.09.016 BindingDB Entry DOI: 10.7270/Q2H41TDB
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50210338 (CHEMBL3926480) Show SMILES [H][C@]1(CCOC)C[C@]1([H])c1cncc(c1)N1C[C@]2([H])C[C@@]1([H])CN2 |r| Show InChI InChI=1S/C16H23N3O/c1-20-3-2-11-5-16(11)12-4-14(8-17-7-12)19-10-13-6-15(19)9-18-13/h4,7-8,11,13,15-16,18H,2-3,5-6,9-10H2,1H3/t11-,13-,15-,16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...				Eur J Med Chem 124: 689-697 (2016) Article DOI: 10.1016/j.ejmech.2016.09.016 BindingDB Entry DOI: 10.7270/Q2H41TDB
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50210335 (CHEMBL3898434) Show SMILES [H][C@@]1(CCOC)C[C@@]1([H])c1cncc(c1)N1CCCNCC1 |r| Show InChI InChI=1S/C16H25N3O/c1-20-8-3-13-10-16(13)14-9-15(12-18-11-14)19-6-2-4-17-5-7-19/h9,11-13,16-17H,2-8,10H2,1H3/t13-,16-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...				Eur J Med Chem 124: 689-697 (2016) Article DOI: 10.1016/j.ejmech.2016.09.016 BindingDB Entry DOI: 10.7270/Q2H41TDB
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50210333 (CHEMBL3908556) Show SMILES CN1CCCN(CC1)c1cncc(c1)-c1cc(CCO)no1 Show InChI InChI=1S/C16H22N4O2/c1-19-4-2-5-20(7-6-19)15-9-13(11-17-12-15)16-10-14(3-8-21)18-22-16/h9-12,21H,2-8H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...				Eur J Med Chem 124: 689-697 (2016) Article DOI: 10.1016/j.ejmech.2016.09.016 BindingDB Entry DOI: 10.7270/Q2H41TDB
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473031 (CHEMBL140652) Show SMILES NCCCNCCCCNCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C27H41N5O3/c28-13-7-16-29-14-4-5-15-30-17-8-18-31-27(35)25(20-23-11-6-12-24(33)19-23)32-26(34)21-22-9-2-1-3-10-22/h1-3,6,9-12,19,25,29-30,33H,4-5,7-8,13-18,20-21,28H2,(H,31,35)(H,32,34)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473026 (CHEMBL141954) Show SMILES CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCOCCCCOCCCN Show InChI InChI=1S/C23H39N3O5/c1-2-7-22(28)26-21(18-19-8-10-20(27)11-9-19)23(29)25-13-6-17-31-15-4-3-14-30-16-5-12-24/h8-11,21,27H,2-7,12-18,24H2,1H3,(H,25,29)(H,26,28)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322514 ((2S,3S)-2-(Naphthalen-2-yl)-3,5,5-trimethylmorphol...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(c1)-c1ccc2ccccc2c1 |r| Show InChI InChI=1S/C23H25NO2/c1-16-23(25,26-15-22(2,3)24-16)21-10-6-9-19(14-21)20-12-11-17-7-4-5-8-18(17)13-20/h4-14,16,24-25H,15H2,1-3H3/t16-,23+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50094298 (CHEMBL16117 | N-[(S)-1-{3-[4-(3-Amino-propylamino)...) Show SMILES CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCNCCCCNCCCN Show InChI InChI=1S/C23H41N5O3/c1-2-7-22(30)28-21(18-19-8-10-20(29)11-9-19)23(31)27-17-6-16-26-14-4-3-13-25-15-5-12-24/h8-11,21,25-26,29H,2-7,12-18,24H2,1H3,(H,27,31)(H,28,30)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473034 (CHEMBL139085) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C27H39N3O5/c28-14-6-18-34-16-4-5-17-35-19-7-15-29-27(33)25(20-23-10-12-24(31)13-11-23)30-26(32)21-22-8-2-1-3-9-22/h1-3,8-13,25,31H,4-7,14-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473027 (CHEMBL137909) Show SMILES NCCCNCCCCNCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C27H47N5O3/c28-14-6-17-29-15-4-5-16-30-18-7-19-31-27(35)25(20-23-10-12-24(33)13-11-23)32-26(34)21-22-8-2-1-3-9-22/h10-13,22,25,29-30,33H,1-9,14-21,28H2,(H,31,35)(H,32,34)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322513 ((2S,3S)-2-(3-Chlorophenyl)-3-ethyl-5,5-dimethylmor...) Show SMILES CC[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C14H20ClNO2/c1-4-12-14(17,18-9-13(2,3)16-12)10-6-5-7-11(15)8-10/h5-8,12,16-17H,4,9H2,1-3H3/t12-,14-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50094299 (CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...) Show SMILES CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCCCCCCCCCCN Show InChI InChI=1S/C25H43N3O3/c1-2-13-24(30)28-23(20-21-14-16-22(29)17-15-21)25(31)27-19-12-10-8-6-4-3-5-7-9-11-18-26/h14-17,23,29H,2-13,18-20,26H2,1H3,(H,27,31)(H,28,30)/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473032 (CHEMBL140491) Show SMILES NCCCCCCCCCCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C29H43N3O3/c30-20-12-7-5-3-1-2-4-6-8-13-21-31-29(35)27(22-25-16-18-26(33)19-17-25)32-28(34)23-24-14-10-9-11-15-24/h9-11,14-19,27,33H,1-8,12-13,20-23,30H2,(H,31,35)(H,32,34)/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322528 ((2S,3S)-2-(3-Bromophenyl)-3,5,5-trimethylmorpholin...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C13H18BrNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3/t9-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322523 ((2S,3S)-2-(4-Chlorophenyl)-3,5,5-trimethylmorpholi...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-4-6-11(14)7-5-10/h4-7,9,15-16H,8H2,1-3H3/t9-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322522 ((2S,3S)-3,5,5-Trimethyl-2-(4-methylphenyl)morpholi...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1ccc(C)cc1 |r| Show InChI InChI=1S/C14H21NO2/c1-10-5-7-12(8-6-10)14(16)11(2)15-13(3,4)9-17-14/h5-8,11,15-16H,9H2,1-4H3/t11-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473025 (CHEMBL137820) Show SMILES NCCCNCCCCNCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C27H41N5O3/c28-14-6-17-29-15-4-5-16-30-18-7-19-31-27(35)25(20-23-10-12-24(33)13-11-23)32-26(34)21-22-8-2-1-3-9-22/h1-3,8-13,25,29-30,33H,4-7,14-21,28H2,(H,31,35)(H,32,34)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322517 ((2S,3S)-2-(3,5-Difluorophenyl)-3,5,5-trimethylmorp...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cc(F)cc(F)c1 |r| Show InChI InChI=1S/C13H17F2NO2/c1-8-13(17,18-7-12(2,3)16-8)9-4-10(14)6-11(15)5-9/h4-6,8,16-17H,7H2,1-3H3/t8-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322521 ((2S,3S)-2-(4-Methoxyphenyl)-3,5,5-trimethylmorphol...) Show SMILES COc1ccc(cc1)[C@]1(O)OCC(C)(C)N[C@H]1C |r| Show InChI InChI=1S/C14H21NO3/c1-10-14(16,18-9-13(2,3)15-10)11-5-7-12(17-4)8-6-11/h5-8,10,15-16H,9H2,1-4H3/t10-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473024 (CHEMBL141800) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C27H39N3O5/c28-13-7-17-34-15-4-5-16-35-18-8-14-29-27(33)25(20-23-11-6-12-24(31)19-23)30-26(32)21-22-9-2-1-3-10-22/h1-3,6,9-12,19,25,31H,4-5,7-8,13-18,20-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473029 (CHEMBL140056) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C27H45N3O5/c28-14-6-18-34-16-4-5-17-35-19-7-15-29-27(33)25(20-23-10-12-24(31)13-11-23)30-26(32)21-22-8-2-1-3-9-22/h10-13,22,25,31H,1-9,14-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322531 ((2R,3R)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...) Show SMILES C[C@H]1NC(C)(C)CO[C@]1(O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C13H18ClNO2/c1-9-13(16,17-8-12(2,3)15-9)10-5-4-6-11(14)7-10/h4-7,9,15-16H,8H2,1-3H3/t9-,13+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473033 (CHEMBL342258) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C27H45N3O5/c28-13-7-17-34-15-4-5-16-35-18-8-14-29-27(33)25(20-23-11-6-12-24(31)19-23)30-26(32)21-22-9-2-1-3-10-22/h6,11-12,19,22,25,31H,1-5,7-10,13-18,20-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322527 ((2S,3S)-2-(m-Tolyl)-3,5,5-trimethylmorpholin-2-ol ...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1cccc(C)c1 |r| Show InChI InChI=1S/C14H21NO2/c1-10-6-5-7-12(8-10)14(16)11(2)15-13(3,4)9-17-14/h5-8,11,15-16H,9H2,1-4H3/t11-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473034 (CHEMBL139085) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C27H39N3O5/c28-14-6-18-34-16-4-5-17-35-19-7-15-29-27(33)25(20-23-10-12-24(31)13-11-23)30-26(32)21-22-8-2-1-3-9-22/h1-3,8-13,25,31H,4-7,14-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322519 ((2S,3S)-2-(3,4-Difluorophenyl)-3,5,5-trimethylmorp...) Show SMILES C[C@@H]1NC(C)(C)CO[C@@]1(O)c1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C13H17F2NO2/c1-8-13(17,18-7-12(2,3)16-8)9-4-5-10(14)11(15)6-9/h4-6,8,16-17H,7H2,1-3H3/t8-,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473037 (CHEMBL336882) Show SMILES CCCC(=O)N[C@@H](Cc1cccc(O)c1)C(=O)NCCCOCCCCOCCCN Show InChI InChI=1S/C23H39N3O5/c1-2-8-22(28)26-21(18-19-9-5-10-20(27)17-19)23(29)25-12-7-16-31-14-4-3-13-30-15-6-11-24/h5,9-10,17,21,27H,2-4,6-8,11-16,18,24H2,1H3,(H,25,29)(H,26,28)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322510 ((2S,3S)-2-(4-Chlorophenyl)-3,4,5,5-tetramethylmorp...) Show SMILES C[C@@H]1N(C)C(C)(C)CO[C@@]1(O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C14H20ClNO2/c1-10-14(17,11-5-7-12(15)8-6-11)18-9-13(2,3)16(10)4/h5-8,10,17H,9H2,1-4H3/t10-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322526 ((2S,3S)-2-(3-Methoxyphenyl)-3,5,5-trimethylmorphol...) Show SMILES COc1cccc(c1)[C@]1(O)OCC(C)(C)N[C@H]1C |r| Show InChI InChI=1S/C14H21NO3/c1-10-14(16,18-9-13(2,3)15-10)11-6-5-7-12(8-11)17-4/h5-8,10,15-16H,9H2,1-4H3/t10-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473024 (CHEMBL141800) Show SMILES NCCCOCCCCOCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C27H39N3O5/c28-13-7-17-34-15-4-5-16-35-18-8-14-29-27(33)25(20-23-11-6-12-24(31)19-23)30-26(32)21-22-9-2-1-3-10-22/h1-3,6,9-12,19,25,31H,4-5,7-8,13-18,20-21,28H2,(H,29,33)(H,30,32)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50094298 (CHEMBL16117 | N-[(S)-1-{3-[4-(3-Amino-propylamino)...) Show SMILES CCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCCNCCCCNCCCN Show InChI InChI=1S/C23H41N5O3/c1-2-7-22(30)28-21(18-19-8-10-20(29)11-9-19)23(31)27-17-6-16-26-14-4-3-13-25-15-5-12-24/h8-11,21,25-26,29H,2-7,12-18,24H2,1H3,(H,27,31)(H,28,30)/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.67E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50322511 ((2S,3S)-2-(3-Chlorophenyl)-3,4,5,5-tetramethylmorp...) Show SMILES C[C@@H]1N(C)C(C)(C)CO[C@@]1(O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C14H20ClNO2/c1-10-14(17,11-6-5-7-12(15)8-11)18-9-13(2,3)16(10)4/h5-8,10,17H,9H2,1-4H3/t10-,14+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Barrow Neurological Institute Curated by ChEMBL					Assay Description Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...				J Med Chem 53: 4731-48 (2010) Article DOI: 10.1021/jm1003232 BindingDB Entry DOI: 10.7270/Q2CF9Q9N
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50473023 (CHEMBL342235) Show SMILES NCCCNCCCCNCCCNC(=O)[C@H](Cc1cccc(O)c1)NC(=O)CC1CCCCC1 Show InChI InChI=1S/C27H47N5O3/c28-13-7-16-29-14-4-5-15-30-17-8-18-31-27(35)25(20-23-11-6-12-24(33)19-23)32-26(34)21-22-9-2-1-3-10-22/h6,11-12,19,22,25,29-30,33H,1-5,7-10,13-18,20-21,28H2,(H,31,35)(H,32,34)/t25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Royal Danish School of Pharmacy Curated by ChEMBL					Assay Description Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (peak value).				J Med Chem 43: 4526-33 (2000) Article DOI: 10.1021/jm000220n BindingDB Entry DOI: 10.7270/Q2F192F2
					More data for this Ligand-Target Pair
Acetylcholine receptor subunit alpha/beta/delta/gamma (Homo sapiens (Human))	BDBM50161764 ((R)-4-chloro-N-(quinuclidin-3-yl)benzamide | (R)-4...) Show SMILES Clc1ccc(cc1)C(=O)N[C@H]1CN2CCC1CC2 |r,wU:10.10,TLB:9:10:14.13:16.17,(9.34,-31.61,;10.67,-32.38,;10.67,-33.92,;12,-34.69,;13.35,-33.92,;13.34,-32.37,;12,-31.6,;14.68,-34.69,;16.01,-33.92,;14.68,-36.23,;16.02,-37,;16.46,-35.89,;16.53,-37.53,;15.18,-38.13,;14.9,-39.53,;16.27,-38.89,;17.81,-39.55,;18,-38.17,)| Show InChI InChI=1S/C14H17ClN2O/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17/h1-4,10,13H,5-9H2,(H,16,18)/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Inhibition of alpha1beta1gammadelta nAChR expressed in TE671cells by FLIPR assay				J Med Chem 49: 4425-36 (2006) Article DOI: 10.1021/jm0602413 BindingDB Entry DOI: 10.7270/Q25B023S
					More data for this Ligand-Target Pair

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