Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 830   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta [7-25] (Oryctolagus cuniculus (rabbit))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	478	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6431 (3-[(6-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyraz...) Show SMILES OCCCNc1cncc(n1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C17H17ClN6O/c18-12-3-1-4-13(7-12)22-17-11-20-9-15(24-17)14-8-19-10-16(23-14)21-5-2-6-25/h1,3-4,7-11,25H,2,5-6H2,(H,21,23)(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	497	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6433 (3-[(4-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cc(ccn1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(10-14)23-18-12-20-11-16(24-18)13-5-7-22-17(9-13)21-6-2-8-25/h1,3-5,7,9-12,25H,2,6,8H2,(H,21,22)(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6433 (3-[(4-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cc(ccn1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(10-14)23-18-12-20-11-16(24-18)13-5-7-22-17(9-13)21-6-2-8-25/h1,3-5,7,9-12,25H,2,6,8H2,(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6436 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-1,3-...) Show SMILES OCCCNc1ncc(s1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C16H16ClN5OS/c17-11-3-1-4-12(7-11)21-15-10-18-8-13(22-15)14-9-20-16(24-14)19-5-2-6-23/h1,3-4,7-10,23H,2,5-6H2,(H,19,20)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6434 (3-[(4-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cnccc1-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-13-3-1-4-14(9-13)23-18-12-21-11-17(24-18)15-5-7-20-10-16(15)22-6-2-8-25/h1,3-5,7,9-12,22,25H,2,6,8H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	761	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Insulin receptor (Homo sapiens (Human))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.69E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6437 ((3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxaz...) Show SMILES OCCCNc1ncc(o1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C16H16ClN5O2/c17-11-3-1-4-12(7-11)21-15-10-18-8-13(22-15)14-9-20-16(24-14)19-5-2-6-23/h1,3-4,7-10,23H,2,5-6H2,(H,19,20)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6434 (3-[(4-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cnccc1-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-13-3-1-4-14(9-13)23-18-12-21-11-17(24-18)15-5-7-20-10-16(15)22-6-2-8-25/h1,3-5,7,9-12,22,25H,2,6,8H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6426 (3-[(5-{6-[(3-chlorophenyl)amino]pyrimidin-4-yl}pyr...) Show SMILES OCCCNc1cncc(c1)-c1cc(Nc2cccc(Cl)c2)ncn1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-18-9-17(22-12-23-18)13-7-16(11-20-10-13)21-5-2-6-25/h1,3-4,7-12,21,25H,2,5-6H2,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6436 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}-1,3-...) Show SMILES OCCCNc1ncc(s1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C16H16ClN5OS/c17-11-3-1-4-12(7-11)21-15-10-18-8-13(22-15)14-9-20-16(24-14)19-5-2-6-23/h1,3-4,7-10,23H,2,5-6H2,(H,19,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.08E+3	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6435 (3-[(6-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1ccc(nc1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-13-3-1-4-14(9-13)23-18-12-20-11-17(24-18)16-6-5-15(10-22-16)21-7-2-8-25/h1,3-6,9-12,21,25H,2,7-8H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6432 (3-[(6-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cccc(n1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-13-4-1-5-14(10-13)22-18-12-20-11-16(24-18)15-6-2-7-17(23-15)21-8-3-9-25/h1-2,4-7,10-12,25H,3,8-9H2,(H,21,23)(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6430 (3-[(5-{5-[(3-chlorophenyl)amino]pyrimidin-4-yl}pyr...) Show SMILES OCCCNc1cncc(c1)-c1ncncc1Nc1cccc(Cl)c1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-17-11-21-12-23-18(17)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,24-25H,2,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6429 (3-[(5-{5-[(3-chlorophenyl)amino]pyrimidin-2-yl}pyr...) Show SMILES OCCCNc1cncc(c1)-c1ncc(Nc2cccc(Cl)c2)cn1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-17-11-22-18(23-12-17)13-7-16(10-20-9-13)21-5-2-6-25/h1,3-4,7-12,21,24-25H,2,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6428 (3-[(5-{5-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cnc(Nc2cccc(Cl)c2)cn1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-18-12-22-17(11-23-18)13-7-16(10-20-9-13)21-5-2-6-25/h1,3-4,7-12,21,25H,2,5-6H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Rattus norvegicus (rat))	BDBM6426 (3-[(5-{6-[(3-chlorophenyl)amino]pyrimidin-4-yl}pyr...) Show SMILES OCCCNc1cncc(c1)-c1cc(Nc2cccc(Cl)c2)ncn1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-18-9-17(22-12-23-18)13-7-16(11-20-10-13)21-5-2-6-25/h1,3-4,7-12,21,25H,2,5-6H2,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6437 ((3-Chlorophenyl){6-[2-((3-hydroxypropyl)amino)oxaz...) Show SMILES OCCCNc1ncc(o1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C16H16ClN5O2/c17-11-3-1-4-12(7-11)21-15-10-18-8-13(22-15)14-9-20-16(24-14)19-5-2-6-23/h1,3-4,7-10,23H,2,5-6H2,(H,19,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6435 (3-[(6-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1ccc(nc1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-13-3-1-4-14(9-13)23-18-12-20-11-17(24-18)16-6-5-15(10-22-16)21-7-2-8-25/h1,3-6,9-12,21,25H,2,7-8H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6432 (3-[(6-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cccc(n1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-13-4-1-5-14(10-13)22-18-12-20-11-16(24-18)15-6-2-7-17(23-15)21-8-3-9-25/h1-2,4-7,10-12,25H,3,8-9H2,(H,21,23)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6431 (3-[(6-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyraz...) Show SMILES OCCCNc1cncc(n1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C17H17ClN6O/c18-12-3-1-4-13(7-12)22-17-11-20-9-15(24-17)14-8-19-10-16(23-14)21-5-2-6-25/h1,3-4,7-11,25H,2,5-6H2,(H,21,23)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6430 (3-[(5-{5-[(3-chlorophenyl)amino]pyrimidin-4-yl}pyr...) Show SMILES OCCCNc1cncc(c1)-c1ncncc1Nc1cccc(Cl)c1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-17-11-21-12-23-18(17)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,24-25H,2,5-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6429 (3-[(5-{5-[(3-chlorophenyl)amino]pyrimidin-2-yl}pyr...) Show SMILES OCCCNc1cncc(c1)-c1ncc(Nc2cccc(Cl)c2)cn1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-17-11-22-18(23-12-17)13-7-16(10-20-9-13)21-5-2-6-25/h1,3-4,7-12,21,24-25H,2,5-6H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6416 (3-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)23-18-12-21-11-17(24-18)13-7-16(10-20-9-13)22-5-2-6-25/h1,3-4,7-12,22,25H,2,5-6H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Homo sapiens (Human))	BDBM6428 (3-[(5-{5-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...) Show SMILES OCCCNc1cncc(c1)-c1cnc(Nc2cccc(Cl)c2)cn1 Show InChI InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(8-14)24-18-12-22-17(11-23-18)13-7-16(10-20-9-13)21-5-2-6-25/h1,3-4,7-12,21,25H,2,5-6H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	30
Johnson & Johnson Pharmaceutical					Assay Description The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...				J Med Chem 48: 1886-900 (2005) Article DOI: 10.1021/jm040099a BindingDB Entry DOI: 10.7270/Q2HM56NC
					More data for this Ligand-Target Pair