BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with all data for entry = 4921
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM78940 (METHIOTHEPIN \| MLS000859918 \| Methiothepin mesylat...) Show SMILES CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	1.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM82087 (2-(5-methoxy-1H-indol-3-yl)ethanamine \| 5-MT \| 5-M...) Show SMILES COc1ccc2[nH]cc(CCN)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	5.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM35256 ((S)-mianserin \| Lerivon \| MIANSERIN \| MIANSERIN (+...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM22869 (6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	31.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	39.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM50014406 (2-Me 5-HT \| 2-Methyl-5-hydroxytryptamine \| 2-methy...) Show SMILES Cc1[nH]c2ccc(O)cc2c1CCN Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM81781 (5-HT,a-Me \| 5-HT,omega-N-Me) Show SMILES Cn1cc(CCN)c2cc(O)ccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (MOUSE)	BDBM82247 (8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by PDSP K_i Database									J Pharmacol Exp Ther 269: 246-55 (1994) Article DOI: 10.1016/j.bioorg.2015.04.003 BindingDB Entry DOI: 10.7270/Q2NS0SDB
University of Pennsylvania Curated by PDSP K_i Database					More data for this Ligand-Target Pair