Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91698 (Oxazolamine derivative, 5a) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91699 (Oxazolamine derivative, 5b) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91700 (Oxazolamine derivative, 5c) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91701 (Oxazolamine derivative, 5d) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91702 (Oxazolamine derivative, 5e) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91706 (1H-tetrazole, 13) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50176808 (5-[(3-Chloro-phenyl)-imidazol-1-yl-methyl]-1H-benz...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM50253810 (CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91704 (1H-1,2,4-triazole, 11) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91705 (1H-1,2,4-triazole, 12) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 26A1 (Homo sapiens (Human)) | BDBM91703 (Oxazolamine derivative, 5f) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a |
Cardiff University | Assay Description The imidazole derivatives were evaluated for their retinoic acid metabolism inhibitory activity using a MCF-7 cell assay, using radiolabelled all-tra... | J Enzyme Inhib Med Chem 24: 487-98 (2009) Article DOI: 10.1080/14756360802218334 BindingDB Entry DOI: 10.7270/Q2CR5RZ5 | |||||||||||
More data for this Ligand-Target Pair |