Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM50382912 (CHEMBL2023209 | US8569299, 4) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM104819 (US8569299, 8) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM50382886 (CHEMBL2024198 | US8569299, 23) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM104816 (US8569299, 2) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.90 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM104818 (US8569299, 7) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM50383424 (CHEMBL2031591 | US8569299, 6) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM104817 (US8569299, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.80 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM50382921 (CHEMBL2024196 | US8569299, 5) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10.7 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM104815 (US8569299, 1) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 13.9 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM50383422 (CHEMBL2031594 | US8569299, 74) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 18 | n/a | n/a | n/a | n/a | 5.5 | 37 |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds against PRCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PRCP inhibitor test compo... | US Patent US8569299 (2013) BindingDB Entry DOI: 10.7270/Q2K9365V | |||||||||||
More data for this Ligand-Target Pair |