Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12656 (((4R,5S)-5-Amino-4-(2,4,5-trifluorophenyl)cyclohex...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.30 | -50.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12654 ((1S,6R)-3-(3-carbamoylphenoxymethyl)-6-(2,4,5-trif...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.60 | -47.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12655 ((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.70 | -47.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12653 ((1S,6R)-3-{[(3-carbamoylphenyl)amino]methyl}-6-(2,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6 | -46.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12652 ((1S,6R)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylmethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 12 | -44.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12651 ((1S,6R)-3-[(4-carboxypiperidin-1-yl)methyl]-6-(2,4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 45 | -41.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM12652 ((1S,6R)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylmethy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 73 | -40.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12650 ((1S,6R)-6-(2-chlorophenyl)-3-phenylcyclohex-3-en-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | <140 | <-38.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM12653 ((1S,6R)-3-{[(3-carbamoylphenyl)amino]methyl}-6-(2,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 230 | -37.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM12652 ((1S,6R)-3-(1,2,3,4-tetrahydroisoquinolin-2-ylmethy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 310 | -36.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM12654 ((1S,6R)-3-(3-carbamoylphenoxymethyl)-6-(2,4,5-trif...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 430 | -36.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM12653 ((1S,6R)-3-{[(3-carbamoylphenyl)amino]methyl}-6-(2,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 500 | -35.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM12654 ((1S,6R)-3-(3-carbamoylphenoxymethyl)-6-(2,4,5-trif...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 560 | -35.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 4 (Homo sapiens (Human)) | BDBM12649 ((1S,6R)-6-(2-chlorophenyl)cyclohex-3-en-1-amine | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 820 | -34.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM12656 (((4R,5S)-5-Amino-4-(2,4,5-trifluorophenyl)cyclohex...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.00E+3 | -30.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM12655 ((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.80E+3 | -28.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 9 (Homo sapiens (Human)) | BDBM12655 ((1S,6R)-3-[(3-carbamoylphenyl)carbamoyl]-6-(2,4,5-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.40E+4 | -27.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dipeptidyl peptidase 8 (Homo sapiens (Human)) | BDBM12656 (((4R,5S)-5-Amino-4-(2,4,5-trifluorophenyl)cyclohex...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >3.00E+4 | >-25.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Abbott Laboratories | Assay Description The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas... | J Med Chem 49: 6439-42 (2006) Article DOI: 10.1021/jm060955d BindingDB Entry DOI: 10.7270/Q2G73BXR | |||||||||||
More data for this Ligand-Target Pair |