Compile Data Set for Download or QSAR

Found 694 hits Enz. Inhib. hit(s) with all data for entry = 6106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108852 (US8604016, 432 | US9938267, Cmpd ID 432) Show SMILES O=C(Cc1cccc(CNC(=O)c2ccccc2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C34H33N7O3S/c42-30(21-24-10-3-1-4-11-24)36-29-19-18-28(38-39-29)16-7-8-17-32-40-41-34(45-32)37-31(43)22-25-12-9-13-26(20-25)23-35-33(44)27-14-5-2-6-15-27/h1-6,9-15,18-20H,7-8,16-17,21-23H2,(H,35,44)(H,36,39,42)(H,37,41,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108853 (US8604016, 433 | US9938267, Cmpd ID 433) Show SMILES CC(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-22(2)17-28(40)33-21-25-12-8-11-24(18-25)20-30(42)35-32-39-38-31(43-32)14-7-6-13-26-15-16-27(37-36-26)34-29(41)19-23-9-4-3-5-10-23/h3-5,8-12,15-16,18,22H,6-7,13-14,17,19-21H2,1-2H3,(H,33,40)(H,34,37,41)(H,35,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM47230 (US8604016, 645 | US9938267, Cmpd ID 645) Show SMILES CCCCS(=O)(=O)Cc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C31H36N6O4S2/c1-2-3-18-43(40,41)22-25-13-9-12-24(19-25)21-28(38)32-27-17-16-26(34-35-27)14-7-8-15-30-36-37-31(42-30)33-29(39)20-23-10-5-4-6-11-23/h4-6,9-13,16-17,19H,2-3,7-8,14-15,18,20-22H2,1H3,(H,32,35,38)(H,33,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108893 (US8604016, 473 | US9938267, Cmpd ID 473) Show SMILES O=C(Cc1cccc(CC(=O)N2CCCC2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C32H35N7O3S/c40-28(20-23-9-2-1-3-10-23)33-27-16-15-26(35-36-27)13-4-5-14-30-37-38-32(43-30)34-29(41)21-24-11-8-12-25(19-24)22-31(42)39-17-6-7-18-39/h1-3,8-12,15-16,19H,4-7,13-14,17-18,20-22H2,(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108895 (US8604016, 475 | US9938267, Cmpd ID 475) Show SMILES Brc1ccc(nn1)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H30BrN9O3S/c33-26-15-14-25(38-39-26)31(45)34-20-23-10-6-9-22(17-23)19-29(44)36-32-42-41-30(46-32)12-5-4-11-24-13-16-27(40-37-24)35-28(43)18-21-7-2-1-3-8-21/h1-3,6-10,13-17H,4-5,11-12,18-20H2,(H,34,45)(H,35,40,43)(H,36,42,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108855 (US8604016, 435 | US9938267, Cmpd ID 435) Show SMILES O=C(Cc1ccccc1)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C35H35N7O3S/c43-31(21-25-10-3-1-4-11-25)36-24-28-15-9-14-27(20-28)23-33(45)38-35-42-41-34(46-35)17-8-7-16-29-18-19-30(40-39-29)37-32(44)22-26-12-5-2-6-13-26/h1-6,9-15,18-20H,7-8,16-17,21-24H2,(H,36,43)(H,37,40,44)(H,38,42,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109060 (US8604016, 644) Show SMILES CCCCS(=O)(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCC(=N)CCC(=N)NC(=O)Cc3ccccc3)s2)c1 Show InChI InChI=1S/C31H40N6O4S2/c1-2-3-18-43(40,41)22-25-13-9-12-24(19-25)21-29(39)35-31-37-36-30(42-31)15-8-7-14-26(32)16-17-27(33)34-28(38)20-23-10-5-4-6-11-23/h4-6,9-13,19,32H,2-3,7-8,14-18,20-22H2,1H3,(H2,33,34,38)(H,35,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108804 (US8604016, 384 | US9938267, Cmpd ID 384) Show SMILES CCOC(=O)NCc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C30H33N7O4S/c1-2-41-30(40)31-20-23-12-8-11-22(17-23)19-26(38)32-25-16-15-24(34-35-25)13-6-7-14-28-36-37-29(42-28)33-27(39)18-21-9-4-3-5-10-21/h3-5,8-12,15-17H,2,6-7,13-14,18-20H2,1H3,(H,31,40)(H,32,35,38)(H,33,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108979 (BDBM108981 | US8604016, 563 | US9938267, Cmpd ID 5...) Show SMILES CCOC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C30H33N7O4S/c1-20(31-30(40)41-2)23-12-8-11-22(17-23)19-27(39)33-29-37-36-28(42-29)14-7-6-13-24-15-16-25(35-34-24)32-26(38)18-21-9-4-3-5-10-21/h3-5,8-12,15-17,20H,6-7,13-14,18-19H2,1-2H3,(H,31,40)(H,32,35,38)(H,33,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108990 (US8604016, 572 | US9938267, Cmpd ID 572) Show SMILES CCOC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(CNC(=O)OCC)c4)nn3)s2)c1 Show InChI InChI=1S/C34H40N8O6S/c1-3-47-33(45)35-21-25-11-7-9-23(17-25)19-29(43)37-28-16-15-27(39-40-28)13-5-6-14-31-41-42-32(49-31)38-30(44)20-24-10-8-12-26(18-24)22-36-34(46)48-4-2/h7-12,15-18H,3-6,13-14,19-22H2,1-2H3,(H,35,45)(H,36,46)(H,37,40,43)(H,38,42,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108994 (US8604016, 576 | US9938267, Cmpd ID 576) Show SMILES CC(C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)c1ccc(O)cc1 Show InChI InChI=1S/C36H37N7O4S/c1-24(28-14-17-30(44)18-15-28)35(47)37-23-27-11-7-10-26(20-27)22-33(46)39-36-43-42-34(48-36)13-6-5-12-29-16-19-31(41-40-29)38-32(45)21-25-8-3-2-4-9-25/h2-4,7-11,14-20,24,44H,5-6,12-13,21-23H2,1H3,(H,37,47)(H,38,41,45)(H,39,43,46)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109041 (US8604016, 623) Show SMILES CS(=O)(=O)CCCOc1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 Show InChI InChI=1S/C30H38N6O5S2/c1-43(39,40)18-8-17-41-25-13-7-11-23(19-25)21-27(37)33-26(32)16-15-24(31)12-5-6-14-29-35-36-30(42-29)34-28(38)20-22-9-3-2-4-10-22/h2-4,7,9-11,13,19,31H,5-6,8,12,14-18,20-21H2,1H3,(H2,32,33,37)(H,34,36,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108915 (US8604016, 496 | US9938267, Cmpd ID 496) Show SMILES CCCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-2-3-18-33-28(40)21-24-12-9-13-25(19-24)22-30(42)35-32-39-38-31(43-32)15-8-7-14-26-16-17-27(37-36-26)34-29(41)20-23-10-5-4-6-11-23/h4-6,9-13,16-17,19H,2-3,7-8,14-15,18,20-22H2,1H3,(H,33,40)(H,34,37,41)(H,35,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108917 (US8604016, 498 | US9938267, Cmpd ID 498) Show SMILES CC(C)N(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-22(2)39(3)31(42)21-25-13-9-12-24(18-25)20-29(41)34-32-38-37-30(43-32)15-8-7-14-26-16-17-27(36-35-26)33-28(40)19-23-10-5-4-6-11-23/h4-6,9-13,16-18,22H,7-8,14-15,19-21H2,1-3H3,(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108935 (US8604016, 516) Show SMILES CCCCNC(=O)Cc1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 Show InChI InChI=1S/C32H41N7O3S/c1-2-3-18-35-28(40)21-24-12-9-13-25(19-24)22-29(41)36-27(34)17-16-26(33)14-7-8-15-31-38-39-32(43-31)37-30(42)20-23-10-5-4-6-11-23/h4-6,9-13,19,33H,2-3,7-8,14-18,20-22H2,1H3,(H,35,40)(H2,34,36,41)(H,37,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108936 (US8604016, 517) Show SMILES CC(C)CNC(=O)Cc1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 Show InChI InChI=1S/C32H41N7O3S/c1-22(2)21-35-28(40)19-24-11-8-12-25(17-24)20-29(41)36-27(34)16-15-26(33)13-6-7-14-31-38-39-32(43-31)37-30(42)18-23-9-4-3-5-10-23/h3-5,8-12,17,22,33H,6-7,13-16,18-21H2,1-2H3,(H,35,40)(H2,34,36,41)(H,37,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108864 (US8604016, 444 | US9938267, Cmpd ID 444) Show SMILES CN(Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(=O)Cc1ccccc1 Show InChI InChI=1S/C36H37N7O3S/c1-43(35(46)24-27-13-6-3-7-14-27)25-29-16-10-15-28(21-29)23-33(45)38-36-42-41-34(47-36)18-9-8-17-30-19-20-31(40-39-30)37-32(44)22-26-11-4-2-5-12-26/h2-7,10-16,19-21H,8-9,17-18,22-25H2,1H3,(H,37,40,44)(H,38,42,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108871 (US8604016, 451 | US9938267, Cmpd ID 451) Show SMILES CC(=O)Nc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C28H29N7O3S/c1-19(36)29-23-12-7-10-21(16-23)18-26(38)31-28-35-34-27(39-28)13-6-5-11-22-14-15-24(33-32-22)30-25(37)17-20-8-3-2-4-9-20/h2-4,7-10,12,14-16H,5-6,11,13,17-18H2,1H3,(H,29,36)(H,30,33,37)(H,31,35,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108873 (US8604016, 453 | US9938267, Cmpd ID 453) Show SMILES CCNC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C30H34N8O3S/c1-2-31-29(41)32-20-23-12-8-11-22(17-23)19-27(40)34-30-38-37-28(42-30)14-7-6-13-24-15-16-25(36-35-24)33-26(39)18-21-9-4-3-5-10-21/h3-5,8-12,15-17H,2,6-7,13-14,18-20H2,1H3,(H2,31,32,41)(H,33,36,39)(H,34,38,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108875 (US8604016, 455 | US9938267, Cmpd ID 455) Show SMILES O=C(Cc1cccc(CCNC(=O)c2ccccc2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1 Show InChI InChI=1S/C35H35N7O3S/c43-31(23-25-10-3-1-4-11-25)37-30-19-18-29(39-40-30)16-7-8-17-33-41-42-35(46-33)38-32(44)24-27-13-9-12-26(22-27)20-21-36-34(45)28-14-5-2-6-15-28/h1-6,9-15,18-19,22H,7-8,16-17,20-21,23-24H2,(H,36,45)(H,37,40,43)(H,38,42,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108876 (US8604016, 456 | US9938267, Cmpd ID 456) Show SMILES CCOC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C30H32N6O4S/c1-2-40-29(39)20-23-12-8-11-22(17-23)19-27(38)32-30-36-35-28(41-30)14-7-6-13-24-15-16-25(34-33-24)31-26(37)18-21-9-4-3-5-10-21/h3-5,8-12,15-17H,2,6-7,13-14,18-20H2,1H3,(H,31,34,37)(H,32,36,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108878 (US8604016, 458 | US9938267, Cmpd ID 458) Show SMILES FC(F)(F)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C29H28F3N7O3S/c30-29(31,32)27(42)33-18-21-10-6-9-20(15-21)17-25(41)35-28-39-38-26(43-28)12-5-4-11-22-13-14-23(37-36-22)34-24(40)16-19-7-2-1-3-8-19/h1-3,6-10,13-15H,4-5,11-12,16-18H2,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108890 (US8604016, 470 | US9938267, Cmpd ID 470) Show SMILES CC(C)CNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-22(2)21-33-28(40)19-24-11-8-12-25(17-24)20-30(42)35-32-39-38-31(43-32)14-7-6-13-26-15-16-27(37-36-26)34-29(41)18-23-9-4-3-5-10-23/h3-5,8-12,15-17,22H,6-7,13-14,18-21H2,1-2H3,(H,33,40)(H,34,37,41)(H,35,39,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108891 (US8604016, 471 | US9938267, Cmpd ID 471) Show SMILES CC(C)(C)CNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C33H39N7O3S/c1-33(2,3)22-34-28(41)20-24-12-9-13-25(18-24)21-30(43)36-32-40-39-31(44-32)15-8-7-14-26-16-17-27(38-37-26)35-29(42)19-23-10-5-4-6-11-23/h4-6,9-13,16-18H,7-8,14-15,19-22H2,1-3H3,(H,34,41)(H,35,38,42)(H,36,40,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108894 (US8604016, 474 | US9938267, Cmpd ID 474) Show SMILES FC1(F)CCN(CC1)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C33H35F2N7O3S/c34-33(35)15-17-42(18-16-33)31(45)22-25-10-6-9-24(19-25)21-29(44)37-32-41-40-30(46-32)12-5-4-11-26-13-14-27(39-38-26)36-28(43)20-23-7-2-1-3-8-23/h1-3,6-10,13-14,19H,4-5,11-12,15-18,20-22H2,(H,36,39,43)(H,37,41,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108903 (US8604016, 484 | US9938267, Cmpd ID 484) Show SMILES CCCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-3-18-39(2)31(42)22-25-13-9-12-24(19-25)21-29(41)34-32-38-37-30(43-32)15-8-7-14-26-16-17-27(36-35-26)33-28(40)20-23-10-5-4-6-11-23/h4-6,9-13,16-17,19H,3,7-8,14-15,18,20-22H2,1-2H3,(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108802 (US8604016, 382 | US9938267, Cmpd ID 382) Show SMILES CCOC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C30H33N7O4S/c1-2-41-30(40)31-20-23-12-8-11-22(17-23)19-27(39)33-29-37-36-28(42-29)14-7-6-13-24-15-16-25(35-34-24)32-26(38)18-21-9-4-3-5-10-21/h3-5,8-12,15-17H,2,6-7,13-14,18-20H2,1H3,(H,31,40)(H,32,35,38)(H,33,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108980 (US8604016, 561 | US9938267, Cmpd ID 562) Show SMILES CCOC(=O)NC(C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O4S/c1-3-42-31(41)32-21(2)24-13-9-12-23(18-24)20-28(40)34-30-38-37-29(43-30)15-8-7-14-25-16-17-26(36-35-25)33-27(39)19-22-10-5-4-6-11-22/h4-6,9-13,16-18,21H,3,7-8,14-15,19-20H2,1-2H3,(H,32,41)(H,33,36,39)(H,34,38,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109042 (US8604016, 624) Show SMILES CC(NC(=O)CC(F)(F)F)c1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 Show InChI InChI=1S/C31H36F3N7O3S/c1-20(37-28(44)19-31(32,33)34)23-11-7-10-22(16-23)18-26(42)38-25(36)15-14-24(35)12-5-6-13-29-40-41-30(45-29)39-27(43)17-21-8-3-2-4-9-21/h2-4,7-11,16,20,35H,5-6,12-15,17-19H2,1H3,(H,37,44)(H2,36,38,42)(H,39,41,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108818 (US8604016, 398 | US9938267, Cmpd ID 398) Show SMILES COc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc(OC)c1 Show InChI InChI=1S/C28H30N6O4S/c1-37-22-14-20(15-23(18-22)38-2)17-26(36)30-28-34-33-27(39-28)11-7-6-10-21-12-13-24(32-31-21)29-25(35)16-19-8-4-3-5-9-19/h3-5,8-9,12-15,18H,6-7,10-11,16-17H2,1-2H3,(H,29,32,35)(H,30,34,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109044 (US8604016, 626) Show SMILES CC(NS(C)(=O)=O)c1cccc(CC(=O)NC(=N)CCC(=N)CCCCc2nnc(NC(=O)Cc3ccccc3)s2)c1 Show InChI InChI=1S/C29H37N7O4S2/c1-20(36-42(2,39)40)23-12-8-11-22(17-23)19-26(37)32-25(31)16-15-24(30)13-6-7-14-28-34-35-29(41-28)33-27(38)18-21-9-4-3-5-10-21/h3-5,8-12,17,20,30,36H,6-7,13-16,18-19H2,1-2H3,(H2,31,32,37)(H,33,35,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109048 (US8604016, 630 | US9938267, Cmpd ID 630) Show SMILES CC(C)(C)OC(=O)NC(C)(C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C34H41N7O4S/c1-33(2,3)45-32(44)37-34(4,5)25-15-11-14-24(20-25)22-29(43)36-31-41-40-30(46-31)17-10-9-16-26-18-19-27(39-38-26)35-28(42)21-23-12-7-6-8-13-23/h6-8,11-15,18-20H,9-10,16-17,21-22H2,1-5H3,(H,37,44)(H,35,39,42)(H,36,41,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109063 (US8604016, 647 | US9938267, Cmpd ID 647) Show SMILES CC(C)CNC(=O)COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C32H37N7O4S/c1-22(2)20-33-30(42)21-43-26-13-8-11-24(17-26)19-28(40)34-27-16-15-25(36-37-27)12-6-7-14-31-38-39-32(44-31)35-29(41)18-23-9-4-3-5-10-23/h3-5,8-11,13,15-17,22H,6-7,12,14,18-21H2,1-2H3,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109064 (US8604016, 648 | US9938267, Cmpd ID 648) Show SMILES Cc1noc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)n1 Show InChI InChI=1S/C30H30N8O3S/c1-20-31-28(41-38-20)19-23-11-7-10-22(16-23)18-26(39)32-25-15-14-24(34-35-25)12-5-6-13-29-36-37-30(42-29)33-27(40)17-21-8-3-2-4-9-21/h2-4,7-11,14-16H,5-6,12-13,17-19H2,1H3,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109065 (US8604016, 649 | US9938267, Cmpd ID 649) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc5CNCc45)nn3)s2)c1 Show InChI InChI=1S/C29H28F3N7O3S/c30-29(31,32)42-22-9-3-5-18(13-22)14-25(40)35-28-39-38-27(43-28)10-2-1-8-21-11-12-24(37-36-21)34-26(41)15-19-6-4-7-20-16-33-17-23(19)20/h3-7,9,11-13,33H,1-2,8,10,14-17H2,(H,34,37,41)(H,35,39,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109068 (US8604016, 652 | US9938267, Cmpd ID 652) Show SMILES Cc1nnc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)o1 Show InChI InChI=1S/C30H30N8O3S/c1-20-33-36-28(41-20)19-23-11-7-10-22(16-23)18-26(39)31-25-15-14-24(34-35-25)12-5-6-13-29-37-38-30(42-29)32-27(40)17-21-8-3-2-4-9-21/h2-4,7-11,14-16H,5-6,12-13,17-19H2,1H3,(H,31,35,39)(H,32,38,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109082 (US10793535, Cmpd ID 666 | US8604016, 666 | US99382...) Show SMILES FC(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C27H26F2N6O3S/c28-26(29)38-21-11-6-9-19(15-21)17-23(36)30-22-14-13-20(32-33-22)10-4-5-12-25-34-35-27(39-25)31-24(37)16-18-7-2-1-3-8-18/h1-3,6-9,11,13-15,26H,4-5,10,12,16-17H2,(H,30,33,36)(H,31,35,37)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109083 (US8604016, 667 | US9938267, Cmpd ID 667) Show SMILES FC(F)(F)COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C28H27F3N6O3S/c29-28(30,31)18-40-22-11-6-9-20(15-22)17-24(38)32-23-14-13-21(34-35-23)10-4-5-12-26-36-37-27(41-26)33-25(39)16-19-7-2-1-3-8-19/h1-3,6-9,11,13-15H,4-5,10,12,16-18H2,(H,32,35,38)(H,33,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109087 (US10793535, Cmpd ID 671 | US8604016, 671 | US99382...) Show SMILES FC(F)(F)Oc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4cccnc4)s3)nn2)c1 Show InChI InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-8-3-5-17(13-20)14-22(37)31-21-11-10-19(33-34-21)7-1-2-9-24-35-36-25(40-24)32-23(38)15-18-6-4-12-30-16-18/h3-6,8,10-13,16H,1-2,7,9,14-15H2,(H,31,34,37)(H,32,36,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108982 (US8604016, 564 | US9938267, Cmpd ID 564) Show SMILES CC(C)(C)C(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C32H37N7O3S/c1-32(2,3)30(42)33-21-24-13-9-12-23(18-24)20-28(41)35-31-39-38-29(43-31)15-8-7-14-25-16-17-26(37-36-25)34-27(40)19-22-10-5-4-6-11-22/h4-6,9-13,16-18H,7-8,14-15,19-21H2,1-3H3,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108991 (US8604016, 573 | US9938267, Cmpd ID 573) Show SMILES COC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4cccc(CNC(=O)OC)c4)nn3)s2)c1 Show InChI InChI=1S/C32H36N8O6S/c1-45-31(43)33-19-23-9-5-7-21(15-23)17-27(41)35-26-14-13-25(37-38-26)11-3-4-12-29-39-40-30(47-29)36-28(42)18-22-8-6-10-24(16-22)20-34-32(44)46-2/h5-10,13-16H,3-4,11-12,17-20H2,1-2H3,(H,33,43)(H,34,44)(H,35,38,41)(H,36,40,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108995 (BDBM108996 | US8604016, 578 | US9938267, Cmpd ID 5...) Show SMILES OC(CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(F)(F)F Show InChI InChI=1S/C30H30F3N7O4S/c31-30(32,33)27(43)28(44)34-18-21-10-6-9-20(15-21)17-25(42)36-29-40-39-26(45-29)12-5-4-11-22-13-14-23(38-37-22)35-24(41)16-19-7-2-1-3-8-19/h1-3,6-10,13-15,27,43H,4-5,11-12,16-18H2,(H,34,44)(H,35,38,41)(H,36,40,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108995 (BDBM108996 | US8604016, 578 | US9938267, Cmpd ID 5...) Show SMILES OC(CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(F)(F)F Show InChI InChI=1S/C30H30F3N7O4S/c31-30(32,33)27(43)28(44)34-18-21-10-6-9-20(15-21)17-25(42)36-29-40-39-26(45-29)12-5-4-11-22-13-14-23(38-37-22)35-24(41)16-19-7-2-1-3-8-19/h1-3,6-10,13-15,27,43H,4-5,11-12,16-18H2,(H,34,44)(H,35,38,41)(H,36,40,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108997 (US8604016, 579 | US9938267, Cmpd ID 579) Show SMILES CC(O)(CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1)C(F)(F)F Show InChI InChI=1S/C32H34F3N7O4S/c1-31(46,32(33,34)35)19-28(45)36-20-23-11-7-10-22(16-23)18-27(44)38-30-42-41-29(47-30)13-6-5-12-24-14-15-25(40-39-24)37-26(43)17-21-8-3-2-4-9-21/h2-4,7-11,14-16,46H,5-6,12-13,17-20H2,1H3,(H,36,45)(H,37,40,43)(H,38,42,44)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109007 (US8604016, 589 | US9938267, Cmpd ID 589) Show SMILES COC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C30H33N7O4S/c1-20(31-30(40)41-2)23-12-8-11-22(17-23)19-26(38)32-25-16-15-24(34-35-25)13-6-7-14-28-36-37-29(42-28)33-27(39)18-21-9-4-3-5-10-21/h3-5,8-12,15-17,20H,6-7,13-14,18-19H2,1-2H3,(H,31,40)(H,32,35,38)(H,33,37,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109009 (US8604016, 591 | US9938267, Cmpd ID 591) Show SMILES CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OCCF)c3)nn2)s1)c1ccccc1 Show InChI InChI=1S/C31H34FN7O4S/c1-21(24-10-3-2-4-11-24)29(41)35-30-39-38-28(44-30)13-6-5-12-25-14-15-26(37-36-25)34-27(40)19-22-8-7-9-23(18-22)20-33-31(42)43-17-16-32/h2-4,7-11,14-15,18,21H,5-6,12-13,16-17,19-20H2,1H3,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109010 (US8604016, 592 | US9938267, Cmpd ID 592) Show SMILES CCNC(=O)OC(C)c1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O4S/c1-3-32-31(41)42-21(2)24-13-9-12-23(18-24)20-28(40)34-30-38-37-29(43-30)15-8-7-14-25-16-17-26(36-35-25)33-27(39)19-22-10-5-4-6-11-22/h4-6,9-13,16-18,21H,3,7-8,14-15,19-20H2,1-2H3,(H,32,41)(H,33,36,39)(H,34,38,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109040 (US8604016, 622 | US9938267, Cmpd ID 622) Show SMILES CC(NC(=O)C(F)(F)F)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 Show InChI InChI=1S/C30H30F3N7O3S/c1-19(34-28(43)30(31,32)33)22-11-7-10-21(16-22)18-25(41)35-24-15-14-23(37-38-24)12-5-6-13-27-39-40-29(44-27)36-26(42)17-20-8-3-2-4-9-20/h2-4,7-11,14-16,19H,5-6,12-13,17-18H2,1H3,(H,34,43)(H,35,38,41)(H,36,40,42)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108905 (US8604016, 486 | US9938267, Cmpd ID 486) Show SMILES CCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O3S/c1-3-38(2)30(41)21-24-13-9-12-23(18-24)20-28(40)33-31-37-36-29(42-31)15-8-7-14-25-16-17-26(35-34-25)32-27(39)19-22-10-5-4-6-11-22/h4-6,9-13,16-18H,3,7-8,14-15,19-21H2,1-2H3,(H,32,35,39)(H,33,37,40)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108916 (US8604016, 497 | US9938267, Cmpd ID 497) Show SMILES CCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 Show InChI InChI=1S/C31H35N7O3S/c1-2-17-32-27(39)20-23-11-8-12-24(18-23)21-29(41)34-31-38-37-30(42-31)14-7-6-13-25-15-16-26(36-35-25)33-28(40)19-22-9-4-3-5-10-22/h3-5,8-12,15-16,18H,2,6-7,13-14,17,19-21H2,1H3,(H,32,39)(H,33,36,40)(H,34,38,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair

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