Compile Data Set for Download or QSAR

Found 78 hits Enz. Inhib. hit(s) with all data for entry = 1675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13271 (BMS-354825 2-Heteroarylamino-thiazole Analog 12p |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cccc(NCCO)n2)s1 Show InChI InChI=1S/C18H18ClN5O2S/c1-11-4-2-5-12(19)16(11)24-17(26)13-10-21-18(27-13)23-15-7-3-6-14(22-15)20-8-9-25/h2-7,10,25H,8-9H2,1H3,(H,24,26)(H2,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<0.200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13277 (BMS-354825 2-Heteroarylamino-thiazole Analog 12v |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(NCCO)nc(C)n2)s1 Show InChI InChI=1S/C18H19ClN6O2S/c1-10-4-3-5-12(19)16(10)25-17(27)13-9-21-18(28-13)24-15-8-14(20-6-7-26)22-11(2)23-15/h3-5,8-9,26H,6-7H2,1-2H3,(H,25,27)(H2,20,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13262 (BMS-354825 2-Heteroarylamino-thiazole Analog 12g |...) Show SMILES Cc1cccc(C)c1NC(=O)c1cnc(Nc2cccnn2)s1 Show InChI InChI=1S/C16H15N5OS/c1-10-5-3-6-11(2)14(10)20-15(22)12-9-17-16(23-12)19-13-7-4-8-18-21-13/h3-9H,1-2H3,(H,20,22)(H,17,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13216 (BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...) Show SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1 Show InChI InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13274 (BMS-354825 2-Heteroarylamino-thiazole Analog 12s |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(ncn2)N2CCOCC2)s1 Show InChI InChI=1S/C19H19ClN6O2S/c1-12-3-2-4-13(20)17(12)25-18(27)14-10-21-19(29-14)24-15-9-16(23-11-22-15)26-5-7-28-8-6-26/h2-4,9-11H,5-8H2,1H3,(H,25,27)(H,21,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13357 (CHEMBL312933 | N-(2-chloro-6-methylphenyl)-2-({6-[...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3cccc(NCCO)n3)sc2c1 Show InChI InChI=1S/C22H20ClN5O2S/c1-13-4-2-5-15(23)20(13)28-21(30)14-8-9-16-17(12-14)31-22(25-16)27-19-7-3-6-18(26-19)24-10-11-29/h2-9,12,29H,10-11H2,1H3,(H,28,30)(H2,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13273 (2-(6-(3-(1H-Imidazol-1-yl)propylamino)pyridin-2-yl...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cccc(NCCCn3ccnc3)n2)s1 Show InChI InChI=1S/C22H22ClN7OS/c1-15-5-2-6-16(23)20(15)29-21(31)17-13-26-22(32-17)28-19-8-3-7-18(27-19)25-9-4-11-30-12-10-24-14-30/h2-3,5-8,10,12-14H,4,9,11H2,1H3,(H,29,31)(H2,25,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13266 (BMS-354825 2-Heteroarylamino-thiazole Analog 12k |...) Show SMILES Cc1ccnc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)c1 Show InChI InChI=1S/C17H15ClN4OS/c1-10-6-7-19-14(8-10)21-17-20-9-13(24-17)16(23)22-15-11(2)4-3-5-12(15)18/h3-9H,1-2H3,(H,22,23)(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13272 (BMS-354825 2-Heteroarylamino-thiazole Analog 12q |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cccc(NCCCN3CCOCC3)n2)s1 Show InChI InChI=1S/C23H27ClN6O2S/c1-16-5-2-6-17(24)21(16)29-22(31)18-15-26-23(33-18)28-20-8-3-7-19(27-20)25-9-4-10-30-11-13-32-14-12-30/h2-3,5-8,15H,4,9-14H2,1H3,(H,29,31)(H2,25,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13265 (BMS-354825 2-Heteroarylamino-thiazole Analog 12j |...) Show SMILES Cc1cccc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)n1 Show InChI InChI=1S/C17H15ClN4OS/c1-10-5-3-7-12(18)15(10)22-16(23)13-9-19-17(24-13)21-14-8-4-6-11(2)20-14/h3-9H,1-2H3,(H,22,23)(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13278 (BMS-354825 2-Heteroarylamino-thiazole Analog 12w |...) Show SMILES Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCC(CO)CC1 Show InChI InChI=1S/C22H25ClN6O2S/c1-13-4-3-5-16(23)20(13)28-21(31)17-11-24-22(32-17)27-18-10-19(26-14(2)25-18)29-8-6-15(12-30)7-9-29/h3-5,10-11,15,30H,6-9,12H2,1-2H3,(H,28,31)(H,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13276 (BMS-354825 2-Heteroarylamino-thiazole Analog 12u |...) Show SMILES Cc1nc(NCCCN2CCOCC2)cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)n1 Show InChI InChI=1S/C23H28ClN7O2S/c1-15-5-3-6-17(24)21(15)30-22(32)18-14-26-23(34-18)29-20-13-19(27-16(2)28-20)25-7-4-8-31-9-11-33-12-10-31/h3,5-6,13-14H,4,7-12H2,1-2H3,(H,30,32)(H2,25,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13268 (BMS-354825 2-Heteroarylamino-thiazole Analog 12m |...) Show SMILES Cc1cc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C17H16ClN5OS/c1-9-5-4-6-12(18)15(9)23-16(24)13-8-19-17(25-13)22-14-7-10(2)20-11(3)21-14/h4-8H,1-3H3,(H,23,24)(H,19,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13259 (BMS-354825 2-Heteroarylamino-thiazole Analog 12d |...) Show SMILES Cc1cccc(C)c1NC(=O)c1cnc(Nc2ccccn2)s1 Show InChI InChI=1S/C17H16N4OS/c1-11-6-5-7-12(2)15(11)21-16(22)13-10-19-17(23-13)20-14-8-3-4-9-18-14/h3-10H,1-2H3,(H,21,22)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13256 (BMS-354825 2-Heteroarylamino-thiazole Analog 12a |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2ccccn2)s1 Show InChI InChI=1S/C16H13ClN4OS/c1-10-5-4-6-11(17)14(10)21-15(22)12-9-19-16(23-12)20-13-7-2-3-8-18-13/h2-9H,1H3,(H,21,22)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13275 (BMS-354825 2-Heteroarylamino-thiazole Analog 12t |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(nc(C)n2)N2CCOCC2)s1 Show InChI InChI=1S/C20H21ClN6O2S/c1-12-4-3-5-14(21)18(12)26-19(28)15-11-22-20(30-15)25-16-10-17(24-13(2)23-16)27-6-8-29-9-7-27/h3-5,10-11H,6-9H2,1-2H3,(H,26,28)(H,22,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13270 (2-[(2,6-dimethylpyrimidin-4-yl)amino]-N-(2,4,6-tri...) Show SMILES Cc1cc(C)c(NC(=O)c2cnc(Nc3cc(C)nc(C)n3)s2)c(C)c1 Show InChI InChI=1S/C19H21N5OS/c1-10-6-11(2)17(12(3)7-10)24-18(25)15-9-20-19(26-15)23-16-8-13(4)21-14(5)22-16/h6-9H,1-5H3,(H,24,25)(H,20,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13261 (BMS-354825 2-Heteroarylamino-thiazole Analog 12f |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cccnn2)s1 Show InChI InChI=1S/C15H12ClN5OS/c1-9-4-2-5-10(16)13(9)20-14(22)11-8-17-15(23-11)19-12-6-3-7-18-21-12/h2-8H,1H3,(H,20,22)(H,17,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13267 (BMS-354825 2-Heteroarylamino-thiazole Analog 12l |...) Show SMILES Cc1cc(C)nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)c1 Show InChI InChI=1S/C18H17ClN4OS/c1-10-7-12(3)21-15(8-10)22-18-20-9-14(25-18)17(24)23-16-11(2)5-4-6-13(16)19/h4-9H,1-3H3,(H,23,24)(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13264 (2-(pyrazin-2-ylamino)-N-(2,4,6-trimethylphenyl)-1,...) Show SMILES Cc1cc(C)c(NC(=O)c2cnc(Nc3cnccn3)s2)c(C)c1 Show InChI InChI=1S/C17H17N5OS/c1-10-6-11(2)15(12(3)7-10)22-16(23)13-8-20-17(24-13)21-14-9-18-4-5-19-14/h4-9H,1-3H3,(H,22,23)(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13260 (2-(pyridin-2-ylamino)-N-(2,4,6-trimethylphenyl)-1,...) Show SMILES Cc1cc(C)c(NC(=O)c2cnc(Nc3ccccn3)s2)c(C)c1 Show InChI InChI=1S/C18H18N4OS/c1-11-8-12(2)16(13(3)9-11)22-17(23)14-10-20-18(24-14)21-15-6-4-5-7-19-15/h4-10H,1-3H3,(H,22,23)(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13263 (BMS-354825 2-Heteroarylamino-thiazole Analog 12h |...) Show SMILES Cc1cnc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)c(C)n1 Show InChI InChI=1S/C17H16ClN5OS/c1-9-5-4-6-12(18)14(9)22-16(24)13-8-20-17(25-13)23-15-11(3)21-10(2)7-19-15/h4-8H,1-3H3,(H,22,24)(H,19,20,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13257 (BMS-354825 2-Heteroarylamino-thiazole Analog 12b |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cccnc2)s1 Show InChI InChI=1S/C16H13ClN4OS/c1-10-4-2-6-12(17)14(10)21-15(22)13-9-19-16(23-13)20-11-5-3-7-18-8-11/h2-9H,1H3,(H,19,20)(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13355 (6-N-(2-chloro-6-methylphenyl)-2-N-cyclopropane-1,3...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)C3CC3)sc2c1 Show InChI InChI=1S/C19H16ClN3O2S/c1-10-3-2-4-13(20)16(10)22-18(25)12-7-8-14-15(9-12)26-19(21-14)23-17(24)11-5-6-11/h2-4,7-9,11H,5-6H2,1H3,(H,22,25)(H,21,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13258 (BMS-354825 2-Heteroarylamino-thiazole Analog 12c |...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2ccncc2)s1 Show InChI InChI=1S/C16H13ClN4OS/c1-10-3-2-4-12(17)14(10)21-15(22)13-9-19-16(23-13)20-11-5-7-18-8-6-11/h2-9H,1H3,(H,21,22)(H,18,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13252 (5-N-(2-chloro-6-methylphenyl)-2-N-(thiophene-3-)-1...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccsc2)s1 Show InChI InChI=1S/C16H12ClN3O2S2/c1-9-3-2-4-11(17)13(9)19-15(22)12-7-18-16(24-12)20-14(21)10-5-6-23-8-10/h2-8H,1H3,(H,19,22)(H,18,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13356 (CHEMBL84624 | N-(2-chloro-6-methylphenyl)-2-[(2,6-...) Show SMILES Cc1cc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cccc2Cl)nc(C)n1 Show InChI InChI=1S/C21H18ClN5OS/c1-11-5-4-6-15(22)19(11)27-20(28)14-7-8-16-17(10-14)29-21(25-16)26-18-9-12(2)23-13(3)24-18/h4-10H,1-3H3,(H,27,28)(H,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13242 (2-[(butylcarbamoyl)amino]-4-methyl-N-(2,4,6-trimet...) Show SMILES CCCCNC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C19H26N4O2S/c1-6-7-8-20-18(25)23-19-21-14(5)16(26-19)17(24)22-15-12(3)9-11(2)10-13(15)4/h9-10H,6-8H2,1-5H3,(H,22,24)(H2,20,21,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13246 (5-N-(2-chloro-6-methylphenyl)-2-N-cyclopropane-1,3...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)C2CC2)s1 Show InChI InChI=1S/C15H14ClN3O2S/c1-8-3-2-4-10(16)12(8)18-14(21)11-7-17-15(22-11)19-13(20)9-5-6-9/h2-4,7,9H,5-6H2,1H3,(H,18,21)(H,17,19,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13269 (BMS-354825 2-Heteroarylamino-thiazole Analog 12n |...) Show SMILES Cc1cc(C)nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)n1 Show InChI InChI=1S/C17H16ClN5OS/c1-9-5-4-6-12(18)14(9)22-15(24)13-8-19-17(25-13)23-16-20-10(2)7-11(3)21-16/h4-8H,1-3H3,(H,22,24)(H,19,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM13242 (2-[(butylcarbamoyl)amino]-4-methyl-N-(2,4,6-trimet...) Show SMILES CCCCNC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C19H26N4O2S/c1-6-7-8-20-18(25)23-19-21-14(5)16(26-19)17(24)22-15-12(3)9-11(2)10-13(15)4/h9-10H,6-8H2,1-5H3,(H,22,24)(H2,20,21,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM13241 (4-methyl-2-[(phenylcarbamoyl)amino]-N-(2,4,6-trime...) Show SMILES Cc1nc(NC(=O)Nc2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C21H22N4O2S/c1-12-10-13(2)17(14(3)11-12)24-19(26)18-15(4)22-21(28-18)25-20(27)23-16-8-6-5-7-9-16/h5-11H,1-4H3,(H,24,26)(H2,22,23,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM13244 (2-[(benzylcarbamoyl)amino]-4-methyl-N-(2,4,6-trime...) Show SMILES Cc1nc(NC(=O)NCc2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C22H24N4O2S/c1-13-10-14(2)18(15(3)11-13)25-20(27)19-16(4)24-22(29-19)26-21(28)23-12-17-8-6-5-7-9-17/h5-11H,12H2,1-4H3,(H,25,27)(H2,23,24,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13236 (5-N-(2-chloro-6-methylphenyl)-4-methyl-2-N-(thioph...) Show SMILES Cc1nc(NC(=O)c2cccs2)sc1C(=O)Nc1c(C)cccc1Cl Show InChI InChI=1S/C17H14ClN3O2S2/c1-9-5-3-6-11(18)13(9)20-16(23)14-10(2)19-17(25-14)21-15(22)12-7-4-8-24-12/h3-8H,1-2H3,(H,20,23)(H,19,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13244 (2-[(benzylcarbamoyl)amino]-4-methyl-N-(2,4,6-trime...) Show SMILES Cc1nc(NC(=O)NCc2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C22H24N4O2S/c1-13-10-14(2)18(15(3)11-13)25-20(27)19-16(4)24-22(29-19)26-21(28)23-12-17-8-6-5-7-9-17/h5-11H,12H2,1-4H3,(H,25,27)(H2,23,24,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13241 (4-methyl-2-[(phenylcarbamoyl)amino]-N-(2,4,6-trime...) Show SMILES Cc1nc(NC(=O)Nc2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C21H22N4O2S/c1-12-10-13(2)17(14(3)11-12)24-19(26)18-15(4)22-21(28-18)25-20(27)23-16-8-6-5-7-9-16/h5-11H,1-4H3,(H,24,26)(H2,22,23,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM13240 (2-[[(Methylamino)-carbonyl]amino]-4-methyl-N-(2,4,...) Show SMILES CNC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C16H20N4O2S/c1-8-6-9(2)12(10(3)7-8)19-14(21)13-11(4)18-16(23-13)20-15(22)17-5/h6-7H,1-5H3,(H,19,21)(H2,17,18,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13234 (4-methyl-2-N-(thiophene-3-)-5-N-(2,4,6-trimethylph...) Show SMILES Cc1nc(NC(=O)c2ccsc2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C19H19N3O2S2/c1-10-7-11(2)15(12(3)8-10)21-18(24)16-13(4)20-19(26-16)22-17(23)14-5-6-25-9-14/h5-9H,1-4H3,(H,21,24)(H,20,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13240 (2-[[(Methylamino)-carbonyl]amino]-4-methyl-N-(2,4,...) Show SMILES CNC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C16H20N4O2S/c1-8-6-9(2)12(10(3)7-8)19-14(21)13-11(4)18-16(23-13)20-15(22)17-5/h6-7H,1-5H3,(H,19,21)(H2,17,18,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM13224 (2-N-benzene-4-methyl-5-N-(2,4,6-trimethylphenyl)-1...) Show SMILES Cc1nc(NC(=O)c2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C21H21N3O2S/c1-12-10-13(2)17(14(3)11-12)23-20(26)18-15(4)22-21(27-18)24-19(25)16-8-6-5-7-9-16/h5-11H,1-4H3,(H,23,26)(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13232 (2-(2-furoylamino)-N-mesityl-4-methyl-1,3-thiazole-...) Show SMILES Cc1nc(NC(=O)c2ccco2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C19H19N3O3S/c1-10-8-11(2)15(12(3)9-10)21-18(24)16-13(4)20-19(26-16)22-17(23)14-6-5-7-25-14/h5-9H,1-4H3,(H,21,24)(H,20,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13235 (5-N-(2-chloro-6-methylphenyl)-4-methyl-2-N-(thioph...) Show SMILES Cc1nc(NC(=O)c2ccsc2)sc1C(=O)Nc1c(C)cccc1Cl Show InChI InChI=1S/C17H14ClN3O2S2/c1-9-4-3-5-12(18)13(9)20-16(23)14-10(2)19-17(25-14)21-15(22)11-6-7-24-8-11/h3-8H,1-2H3,(H,20,23)(H,19,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13223 (2-acetamido-4-methyl-N-(2,4,6-trimethylphenyl)-1,3...) Show SMILES CC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C16H19N3O2S/c1-8-6-9(2)13(10(3)7-8)19-15(21)14-11(4)17-16(22-14)18-12(5)20/h6-7H,1-5H3,(H,19,21)(H,17,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM13223 (2-acetamido-4-methyl-N-(2,4,6-trimethylphenyl)-1,3...) Show SMILES CC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C16H19N3O2S/c1-8-6-9(2)13(10(3)7-8)19-15(21)14-11(4)17-16(22-14)18-12(5)20/h6-7H,1-5H3,(H,19,21)(H,17,18,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13245 (2-[(butylcarbamoyl)amino]-N-(2-chloro-6-methylphen...) Show SMILES CCCCNC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cccc1Cl Show InChI InChI=1S/C17H21ClN4O2S/c1-4-5-9-19-16(24)22-17-20-11(3)14(25-17)15(23)21-13-10(2)7-6-8-12(13)18/h6-8H,4-5,9H2,1-3H3,(H,21,23)(H2,19,20,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13222 (2-[[(Methoxy)carbonyl]-amino]-4-methyl-N-(2,4,6-tr...) Show SMILES COC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C16H19N3O3S/c1-8-6-9(2)12(10(3)7-8)18-14(20)13-11(4)17-15(23-13)19-16(21)22-5/h6-7H,1-5H3,(H,18,20)(H,17,19,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13237 (5-N-(2-chloro-6-methylphenyl)-2-N-(furan-2-)-4-met...) Show SMILES Cc1nc(NC(=O)c2ccco2)sc1C(=O)Nc1c(C)cccc1Cl Show InChI InChI=1S/C17H14ClN3O3S/c1-9-5-3-6-11(18)13(9)20-16(23)14-10(2)19-17(25-14)21-15(22)12-7-4-8-24-12/h3-8H,1-2H3,(H,20,23)(H,19,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM13222 (2-[[(Methoxy)carbonyl]-amino]-4-methyl-N-(2,4,6-tr...) Show SMILES COC(=O)Nc1nc(C)c(s1)C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C16H19N3O3S/c1-8-6-9(2)12(10(3)7-8)18-14(20)13-11(4)17-15(23-13)19-16(21)22-5/h6-7H,1-5H3,(H,18,20)(H,17,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	720	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13224 (2-N-benzene-4-methyl-5-N-(2,4,6-trimethylphenyl)-1...) Show SMILES Cc1nc(NC(=O)c2ccccc2)sc1C(=O)Nc1c(C)cc(C)cc1C Show InChI InChI=1S/C21H21N3O2S/c1-12-10-13(2)17(14(3)11-12)23-20(26)18-15(4)22-21(27-18)24-19(25)16-8-6-5-7-9-16/h5-11H,1-4H3,(H,23,26)(H,22,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	7.0	22
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM13250 (2-N-benzene-5-N-(2-chloro-6-methylphenyl)-1,3-thia...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccccc2)s1 Show InChI InChI=1S/C18H14ClN3O2S/c1-11-6-5-9-13(19)15(11)21-17(24)14-10-20-18(25-14)22-16(23)12-7-3-2-4-8-12/h2-10H,1H3,(H,21,24)(H,20,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] lab...				J Med Chem 49: 6819-32 (2006) Article DOI: 10.1021/jm060727j BindingDB Entry DOI: 10.7270/Q2QN6501
					More data for this Ligand-Target Pair

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