BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 6319
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123054 (US8742134, (1)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.160	-55.3	0.230	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123055 (US8742134, (2) \| US8742134, (7)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.180	-55.1	0.25	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123056 (US8742134, (3) \| US8742134, (8)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.180	-55.1	0.25	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123057 (US8742134, (4) \| US8742134, (5) \| US8742134, (6)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.220	-54.6	0.300	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123057 (US8742134, (4) \| US8742134, (5) \| US8742134, (6)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.5	-49.9	2.10	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123057 (US8742134, (4) \| US8742134, (5) \| US8742134, (6)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.10	-49.0	2.90	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123055 (US8742134, (2) \| US8742134, (7)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14	-44.4	19	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123056 (US8742134, (3) \| US8742134, (8)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	26	-42.9	36	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair