Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase (Schistosoma mansoni (flatworms)) | BDBM130378 (2(S)-amino-6-boronohexanoic acid (ABH)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description Briefly, 0.5-50 mM L-arginine (pH 8.5) was added to a solution of 50 mM 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (EPPS) (pH 8.5) and 100 &... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Schistosoma mansoni (flatworms)) | BDBM130379 (N-hydroxy-L-arginine (NOHA)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description Briefly, 0.5-50 mM L-arginine (pH 8.5) was added to a solution of 50 mM 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (EPPS) (pH 8.5) and 100 &... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Schistosoma mansoni (flatworms)) | BDBM130379 (N-hydroxy-L-arginine (NOHA)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Schistosoma mansoni (flatworms)) | BDBM130380 (nor-N-hydroxy-L-arginine (nor-NOHA)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 360 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Schistosoma mansoni (flatworms)) | BDBM50427900 ((R)-2-amino-6-borono-2-[2-(piperidin-1-yl)ethyl]he...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 260 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Schistosoma mansoni (flatworms)) | BDBM130381 ((R)-2-amino-6-borono-2-[1-(3,4-dichlorobenzyl)pipe...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 540 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Schistosoma mansoni (flatworms)) | BDBM130378 (2(S)-amino-6-boronohexanoic acid (ABH)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (Schistosoma mansoni (flatworms)) | BDBM130379 (N-hydroxy-L-arginine (NOHA)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 330 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair |