BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 6460
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Arginase (Schistosoma mansoni (flatworms))	BDBM130378 (2(S)-amino-6-boronohexanoic acid (ABH)) Show SMILES N[C@@H](CCCCB(O)O)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description Briefly, 0.5-50 mM L-arginine (pH 8.5) was added to a solution of 50 mM 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (EPPS) (pH 8.5) and 100 &...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair
Arginase (Schistosoma mansoni (flatworms))	BDBM130379 (N-hydroxy-L-arginine (NOHA)) Show SMILES NC(=N)NCCC[C@H](NO)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description Briefly, 0.5-50 mM L-arginine (pH 8.5) was added to a solution of 50 mM 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (EPPS) (pH 8.5) and 100 &...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair
Arginase (Schistosoma mansoni (flatworms))	BDBM130379 (N-hydroxy-L-arginine (NOHA)) Show SMILES NC(=N)NCCC[C@H](NO)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair
Arginase (Schistosoma mansoni (flatworms))	BDBM130380 (nor-N-hydroxy-L-arginine (nor-NOHA)) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	360	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair
Arginase (Schistosoma mansoni (flatworms))	BDBM50427900 ((R)-2-amino-6-borono-2-[2-(piperidin-1-yl)ethyl]he...) Show SMILES N[C@](CCCCB(O)O)(CCN1CCCCC1)C(O)=O \|r\| Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	260	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair
Arginase (Schistosoma mansoni (flatworms))	BDBM130381 ((R)-2-amino-6-borono-2-[1-(3,4-dichlorobenzyl)pipe...) Show SMILES Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	540	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair
Arginase (Schistosoma mansoni (flatworms))	BDBM130378 (2(S)-amino-6-boronohexanoic acid (ABH)) Show SMILES N[C@@H](CCCCB(O)O)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair
Arginase (Schistosoma mansoni (flatworms))	BDBM130379 (N-hydroxy-L-arginine (NOHA)) Show SMILES NC(=N)NCCC[C@H](NO)C(O)=O Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	330	n/a	n/a	n/a	8.5	n/a
University of Pennsylvania					Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa...				Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ
University of Pennsylvania					More data for this Ligand-Target Pair