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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coagulation factor VII (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | MMDB PC cid PC sid PDB UniChem | MMDB PDB Article PubMed | 0.350 | -53.4 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair |  3D Structure (crystal) | ||||||||||||
| Vitamin K-dependent protein C (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | 87 | -39.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Plasma kallikrein (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | 114 | -39.2 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Plasminogen (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | 1.20E+3 | -33.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | >3.40E+3 | >-30.9 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Coagulation factor X (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | >3.50E+3 | >-30.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prothrombin (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | 3.60E+3 | -30.8 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Tissue-type plasminogen activator (Homo sapiens (Human)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | >3.90E+3 | >-30.6 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Serine protease 1 (Bos taurus (bovine)) | BDBM14714 ((2R)-N-[(3-aminobenzene)sulfonyl]-2-[(4-carbamimid...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | MMDB PC cid PC sid PDB UniChem | Article PubMed | 4.00E+3 | -30.5 | n/a | n/a | n/a | n/a | n/a | 7.8 | 22 |
Genentech | Assay Description The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su... | J Biol Chem 280: 9160-9 (2005) Article DOI: 10.1074/jbc.M409068200 BindingDB Entry DOI: 10.7270/Q2JM27W3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
