Compile Data Set for Download or QSAR

Found 52 hits Enz. Inhib. hit(s) with all data for entry = 1943   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM14711 (Asinex compound no. 6 | N-(3,5-Dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-12(3-2-4-13(8)18(20)21)14(19)17-11-6-9(15)5-10(16)7-11/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM14710 (ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...) Show SMILES Cc1cc(Br)ccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14BrNO/c1-12-10-16(19)8-9-17(12)20-18(21)15-7-6-13-4-2-3-5-14(13)11-15/h2-11H,1H3,(H,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM14710 (ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...) Show SMILES Cc1cc(Br)ccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14BrNO/c1-12-10-16(19)8-9-17(12)20-18(21)15-7-6-13-4-2-3-5-14(13)11-15/h2-11H,1H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15349 (Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrN2O3/c1-9-12(6-3-7-13(9)17(19)20)14(18)16-11-5-2-4-10(15)8-11/h2-8H,1H3,(H,16,18)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15353 (2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c1-12-14(9-5-11-17(12)20(22)23)18(21)19-16-10-4-7-13-6-2-3-8-15(13)16/h2-11H,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15350 (ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H10ClFN2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-12(16)11(15)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15357 (3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...) Show SMILES COc1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c1-22-17-12-5-4-10-16(17)20-18(21)19-15-11-6-8-13-7-2-3-9-14(13)15/h2-12H,1H3,(H2,19,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15357 (3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...) Show SMILES COc1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c1-22-17-12-5-4-10-16(17)20-18(21)19-15-11-6-8-13-7-2-3-9-14(13)15/h2-12H,1H3,(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15352 (ChemBridge compound no. 7 | N-(3,4-difluorophenyl)...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15348 (ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...) Show SMILES Fc1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12FNO/c18-15-7-3-4-8-16(15)19-17(20)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15356 (1-naphthalen-1-yl-3-[2-(trifluoromethyl)phenyl]ure...) Show SMILES FC(F)(F)c1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13F3N2O/c19-18(20,21)14-9-3-4-10-16(14)23-17(24)22-15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H2,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15356 (1-naphthalen-1-yl-3-[2-(trifluoromethyl)phenyl]ure...) Show SMILES FC(F)(F)c1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13F3N2O/c19-18(20,21)14-9-3-4-10-16(14)23-17(24)22-15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H2,22,23,24)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM14711 (Asinex compound no. 6 | N-(3,5-Dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-12(3-2-4-13(8)18(20)21)14(19)17-11-6-9(15)5-10(16)7-11/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15348 (ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...) Show SMILES Fc1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12FNO/c18-15-7-3-4-8-16(15)19-17(20)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15353 (2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c1-12-14(9-5-11-17(12)20(22)23)18(21)19-16-10-4-7-13-6-2-3-8-15(13)16/h2-11H,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15350 (ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H10ClFN2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-12(16)11(15)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM15358 (3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...) Show SMILES Clc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 Show InChI InChI=1S/C16H12ClN3O/c17-12-6-8-13(9-7-12)19-16(21)20-14-5-1-3-11-4-2-10-18-15(11)14/h1-10H,(H2,19,20,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	8.0	22
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15352 (ChemBridge compound no. 7 | N-(3,4-difluorophenyl)...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15349 (Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrN2O3/c1-9-12(6-3-7-13(9)17(19)20)14(18)16-11-5-2-4-10(15)8-11/h2-8H,1H3,(H,16,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15358 (3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...) Show SMILES Clc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 Show InChI InChI=1S/C16H12ClN3O/c17-12-6-8-13(9-7-12)19-16(21)20-14-5-1-3-11-4-2-10-18-15(11)14/h1-10H,(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [R265A] (Plasmodium falciparum)	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15348 (ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...) Show SMILES Fc1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12FNO/c18-15-7-3-4-8-16(15)19-17(20)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15345 (Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...) Show SMILES Clc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 Show InChI InChI=1S/C17H11Cl2NO/c18-14-7-8-16(15(19)10-14)20-17(21)13-6-5-11-3-1-2-4-12(11)9-13/h1-10H,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15354 (Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15353 (2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c1-12-14(9-5-11-17(12)20(22)23)18(21)19-16-10-4-7-13-6-2-3-8-15(13)16/h2-11H,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15349 (Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrN2O3/c1-9-12(6-3-7-13(9)17(19)20)14(18)16-11-5-2-4-10(15)8-11/h2-8H,1H3,(H,16,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15357 (3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...) Show SMILES COc1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c1-22-17-12-5-4-10-16(17)20-18(21)19-15-11-6-8-13-7-2-3-9-14(13)15/h2-12H,1H3,(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15350 (ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H10ClFN2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-12(16)11(15)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15358 (3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...) Show SMILES Clc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 Show InChI InChI=1S/C16H12ClN3O/c17-12-6-8-13(9-7-12)19-16(21)20-14-5-1-3-11-4-2-10-18-15(11)14/h1-10H,(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15350 (ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C14H10ClFN2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-12(16)11(15)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM14711 (Asinex compound no. 6 | N-(3,5-Dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-12(3-2-4-13(8)18(20)21)14(19)17-11-6-9(15)5-10(16)7-11/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15349 (Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(Br)c1 Show InChI InChI=1S/C14H11BrN2O3/c1-9-12(6-3-7-13(9)17(19)20)14(18)16-11-5-2-4-10(15)8-11/h2-8H,1H3,(H,16,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15357 (3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...) Show SMILES COc1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H16N2O2/c1-22-17-12-5-4-10-16(17)20-18(21)19-15-11-6-8-13-7-2-3-9-14(13)15/h2-12H,1H3,(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15355 (2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H11F3N2O3/c1-9-12(6-3-7-13(9)20(22)23)14(21)19-11-5-2-4-10(8-11)15(16,17)18/h2-8H,1H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15353 (2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H14N2O3/c1-12-14(9-5-11-17(12)20(22)23)18(21)19-16-10-4-7-13-6-2-3-8-15(13)16/h2-11H,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15356 (1-naphthalen-1-yl-3-[2-(trifluoromethyl)phenyl]ure...) Show SMILES FC(F)(F)c1ccccc1NC(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C18H13F3N2O/c19-18(20,21)14-9-3-4-10-16(14)23-17(24)22-15-11-5-7-12-6-1-2-8-13(12)15/h1-11H,(H2,22,23,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM15352 (ChemBridge compound no. 7 | N-(3,4-difluorophenyl)...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM14711 (Asinex compound no. 6 | N-(3,5-Dichlorophenyl)-2-m...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C14H10Cl2N2O3/c1-8-12(3-2-4-13(8)18(20)21)14(19)17-11-6-9(15)5-10(16)7-11/h2-7H,1H3,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15348 (ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...) Show SMILES Fc1ccccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C17H12FNO/c18-15-7-3-4-8-16(15)19-17(20)14-10-9-12-5-1-2-6-13(12)11-14/h1-11H,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [30-395] (Homo sapiens (Human))	BDBM14710 (ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...) Show SMILES Cc1cc(Br)ccc1NC(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C18H14BrNO/c1-12-10-16(19)8-9-17(12)20-18(21)15-7-6-13-4-2-3-5-14(13)11-15/h2-11H,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15352 (ChemBridge compound no. 7 | N-(3,4-difluorophenyl)...) Show SMILES Cc1c(cccc1[N+]([O-])=O)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C14H10F2N2O3/c1-8-10(3-2-4-13(8)18(20)21)14(19)17-9-5-6-11(15)12(16)7-9/h2-7H,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair
Dihydroorotate dehydrogenase (quinone), mitochondrial [H185A] (Plasmodium falciparum)	BDBM15358 (3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...) Show SMILES Clc1ccc(NC(=O)Nc2cccc3cccnc23)cc1 Show InChI InChI=1S/C16H12ClN3O/c17-12-6-8-13(9-7-12)19-16(21)20-14-5-1-3-11-4-2-10-18-15(11)14/h1-10H,(H2,19,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center					Assay Description The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...				J Biol Chem 280: 21847-53 (2005) Article DOI: 10.1074/jbc.M501100200 BindingDB Entry DOI: 10.7270/Q21G0JH3
					More data for this Ligand-Target Pair

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