Compile Data Set for Download or QSAR

Found 72 hits Enz. Inhib. hit(s) with all data for entry = 6769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Menin (Homo sapiens (Human))	BDBM152235 (US8993552, 70) Show SMILES CCCc1cc2c(ncnc2s1)N1CCN(CC1)C1=NCC(C)(C)S1 |t:21| Show InChI InChI=1S/C18H25N5S2/c1-4-5-13-10-14-15(20-12-21-16(14)24-13)22-6-8-23(9-7-22)17-19-11-18(2,3)25-17/h10,12H,4-9,11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Menin (Homo sapiens (Human))	BDBM152232 (US8993552, 67) Show SMILES CC(C)c1cc2c(ncnc2s1)N1CCN(CC1)C1=NCC(C)(C)S1 |t:21| Show InChI InChI=1S/C18H25N5S2/c1-12(2)14-9-13-15(20-11-21-16(13)24-14)22-5-7-23(8-6-22)17-19-10-18(3,4)25-17/h9,11-12H,5-8,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152231 (US8993552, 66) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC1)c1nnc(s1)C(F)(F)F Show InChI InChI=1S/C15H15F3N6S2/c1-2-9-7-10-11(19-8-20-12(10)25-9)23-3-5-24(6-4-23)14-22-21-13(26-14)15(16,17)18/h7-8H,2-6H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152211 (BDBM152229 | US8993552, 1) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12 |c:4| Show InChI InChI=1S/C19H25N5S2/c1-19(2)11-20-18(26-19)24-9-7-23(8-10-24)16-15-13-5-3-4-6-14(13)25-17(15)22-12-21-16/h12H,3-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152230 (US8993552, 65) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC1)C1=NCC(C)(C)S1 |t:20| Show InChI InChI=1S/C17H23N5S2/c1-4-12-9-13-14(19-11-20-15(13)23-12)21-5-7-22(8-6-21)16-18-10-17(2,3)24-16/h9,11H,4-8,10H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152245 (US8993552, 80) Show SMILES CCc1cc2c(NC3CCN(Cc4ccccc4)CC3)ncnc2s1 Show InChI InChI=1S/C20H24N4S/c1-2-17-12-18-19(21-14-22-20(18)25-17)23-16-8-10-24(11-9-16)13-15-6-4-3-5-7-15/h3-7,12,14,16H,2,8-11,13H2,1H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152211 (BDBM152229 | US8993552, 1) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12 |c:4| Show InChI InChI=1S/C19H25N5S2/c1-19(2)11-20-18(26-19)24-9-7-23(8-10-24)16-15-13-5-3-4-6-14(13)25-17(15)22-12-21-16/h12H,3-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152211 (BDBM152229 | US8993552, 1) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc3CCCCc3c12 |c:4| Show InChI InChI=1S/C19H25N5S2/c1-19(2)11-20-18(26-19)24-9-7-23(8-10-24)16-15-13-5-3-4-6-14(13)25-17(15)22-12-21-16/h12H,3-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152233 (US8993552, 68) Show SMILES CC(C)c1cc2c(ncnc2s1)N1CCN(CC1)c1nnc(s1)C(F)(F)F Show InChI InChI=1S/C16H17F3N6S2/c1-9(2)11-7-10-12(20-8-21-13(10)26-11)24-3-5-25(6-4-24)15-23-22-14(27-15)16(17,18)19/h7-9H,3-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152224 (US8993552, 4) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC1)c1nnc(CC)s1 Show InChI InChI=1S/C16H20N6S2/c1-3-11-9-12-14(17-10-18-15(12)23-11)21-5-7-22(8-6-21)16-20-19-13(4-2)24-16/h9-10H,3-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152247 (US8993552, 82) Show SMILES CCc1cc2c(NCC3CCN(Cc4ccc(F)cc4)CC3)ncnc2s1 Show InChI InChI=1S/C21H25FN4S/c1-2-18-11-19-20(24-14-25-21(19)27-18)23-12-15-7-9-26(10-8-15)13-16-3-5-17(22)6-4-16/h3-6,11,14-15H,2,7-10,12-13H2,1H3,(H,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152236 (US8993552, 71) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc(Cc3ccccc3)cc12 |c:4| Show InChI InChI=1S/C22H25N5S2/c1-22(2)14-23-21(29-22)27-10-8-26(9-11-27)19-18-13-17(28-20(18)25-15-24-19)12-16-6-4-3-5-7-16/h3-7,13,15H,8-12,14H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152237 (US8993552, 72) Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc(Br)cc12 |c:4| Show InChI InChI=1S/C15H18BrN5S2/c1-15(2)8-17-14(23-15)21-5-3-20(4-6-21)12-10-7-11(16)22-13(10)19-9-18-12/h7,9H,3-6,8H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152241 (US8993552, 76) Show SMILES CCc1cc2c(ncnc2s1)N1CCCN(CC1)C1=NCC(C)(C)S1 |t:21| Show InChI InChI=1S/C18H25N5S2/c1-4-13-10-14-15(20-12-21-16(14)24-13)22-6-5-7-23(9-8-22)17-19-11-18(2,3)25-17/h10,12H,4-9,11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152249 (US8993552, 32) Show SMILES CC(=O)N1C(C2=C(CC(CC2=O)c2ccc(cc2)C(C)(C)C)Nc2ccccc12)c1cccnc1 |t:5| Show InChI InChI=1S/C30H31N3O2/c1-19(34)33-26-10-6-5-9-24(26)32-25-16-22(20-11-13-23(14-12-20)30(2,3)4)17-27(35)28(25)29(33)21-8-7-15-31-18-21/h5-15,18,22,29,32H,16-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152239 (US8993552, 74) Show SMILES CCc1cc2c(ncnc2s1)N1CCCN(CC(=O)N2CCCC2)CC1 Show InChI InChI=1S/C19H27N5OS/c1-2-15-12-16-18(20-14-21-19(16)26-15)24-9-5-6-22(10-11-24)13-17(25)23-7-3-4-8-23/h12,14H,2-11,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152259 (US8993552, 86) Show SMILES CC(=O)N1C(C2=C(CC(CC2=O)c2ccc(Cl)c(Cl)c2)Nc2ccccc12)c1cccnc1 |t:5| Show InChI InChI=1S/C26H21Cl2N3O2/c1-15(32)31-23-7-3-2-6-21(23)30-22-12-18(16-8-9-19(27)20(28)11-16)13-24(33)25(22)26(31)17-5-4-10-29-14-17/h2-11,14,18,26,30H,12-13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152242 (US8993552, 77) Show SMILES Cc1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C Show InChI InChI=1S/C20H24N4S/c1-14-15(2)25-20-18(14)19(21-13-22-20)23-17-8-10-24(11-9-17)12-16-6-4-3-5-7-16/h3-7,13,17H,8-12H2,1-2H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM50302435 ((4-(6-ethylthieno[2,3-d]pyrimidin-4-yl)piperazin-1...) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC1)C(=O)c1ccccc1 Show InChI InChI=1S/C19H20N4OS/c1-2-15-12-16-17(20-13-21-18(16)25-15)22-8-10-23(11-9-22)19(24)14-6-4-3-5-7-14/h3-7,12-13H,2,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152243 (US8993552, 78) Show SMILES C(N1CCC(CC1)Nc1ncnc2sc3CCCc3c12)c1ccccc1 Show InChI InChI=1S/C21H24N4S/c1-2-5-15(6-3-1)13-25-11-9-16(10-12-25)24-20-19-17-7-4-8-18(17)26-21(19)23-14-22-20/h1-3,5-6,14,16H,4,7-13H2,(H,22,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152228 (US8993552, 63) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C17H18N4O2S/c1-2-12-10-13-15(18-11-19-16(13)24-12)20-5-7-21(8-6-20)17(22)14-4-3-9-23-14/h3-4,9-11H,2,5-8H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152251 (US8993552, 34) Show SMILES CC1(C)CC(=O)C2=C(C1)Nc1ccccc1NC2c1ccc2OCOc2c1 |c:6| Show InChI InChI=1S/C22H22N2O3/c1-22(2)10-16-20(17(25)11-22)21(24-15-6-4-3-5-14(15)23-16)13-7-8-18-19(9-13)27-12-26-18/h3-9,21,23-24H,10-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152249 (US8993552, 32) Show SMILES CC(=O)N1C(C2=C(CC(CC2=O)c2ccc(cc2)C(C)(C)C)Nc2ccccc12)c1cccnc1 |t:5| Show InChI InChI=1S/C30H31N3O2/c1-19(34)33-26-10-6-5-9-24(26)32-25-16-22(20-11-13-23(14-12-20)30(2,3)4)17-27(35)28(25)29(33)21-8-7-15-31-18-21/h5-15,18,22,29,32H,16-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152234 (US8993552, 69) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC(=O)N2CCN(C)CC2)CC1 Show InChI InChI=1S/C19H28N6OS/c1-3-15-12-16-18(20-14-21-19(16)27-15)25-10-6-23(7-11-25)13-17(26)24-8-4-22(2)5-9-24/h12,14H,3-11,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152227 (US8993552, 61) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC(=O)N2CCOCC2)CC1 Show InChI InChI=1S/C18H25N5O2S/c1-2-14-11-15-17(19-13-20-18(15)26-14)23-5-3-21(4-6-23)12-16(24)22-7-9-25-10-8-22/h11,13H,2-10,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152244 (US8993552, 79) Show SMILES CC1CCc2c(C1)sc1ncnc(NC3CCN(Cc4ccccc4)CC3)c21 Show InChI InChI=1S/C23H28N4S/c1-16-7-8-19-20(13-16)28-23-21(19)22(24-15-25-23)26-18-9-11-27(12-10-18)14-17-5-3-2-4-6-17/h2-6,15-16,18H,7-14H2,1H3,(H,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152238 (US8993552, 73) Show SMILES COc1ccc(CN2CCCN(CC2)c2ncnc3sc(C)c(C)c23)cc1 Show InChI InChI=1S/C21H26N4OS/c1-15-16(2)27-21-19(15)20(22-14-23-21)25-10-4-9-24(11-12-25)13-17-5-7-18(26-3)8-6-17/h5-8,14H,4,9-13H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152248 (US8993552, 83) Show SMILES CCN(CCNc1ncnc2sc(CC)cc12)Cc1ccccc1 Show InChI InChI=1S/C19H24N4S/c1-3-16-12-17-18(21-14-22-19(17)24-16)20-10-11-23(4-2)13-15-8-6-5-7-9-15/h5-9,12,14H,3-4,10-11,13H2,1-2H3,(H,20,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152250 (US8993552, 33) Show SMILES CC(=O)N1C(C2=C(CC(CC2=O)c2ccc(cc2)C(C)(C)C)Nc2ccccc12)c1ccncc1 |t:5| Show InChI InChI=1S/C30H31N3O2/c1-19(34)33-26-8-6-5-7-24(26)32-25-17-22(20-9-11-23(12-10-20)30(2,3)4)18-27(35)28(25)29(33)21-13-15-31-16-14-21/h5-16,22,29,32H,17-18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152250 (US8993552, 33) Show SMILES CC(=O)N1C(C2=C(CC(CC2=O)c2ccc(cc2)C(C)(C)C)Nc2ccccc12)c1ccncc1 |t:5| Show InChI InChI=1S/C30H31N3O2/c1-19(34)33-26-8-6-5-7-24(26)32-25-17-22(20-9-11-23(12-10-20)30(2,3)4)18-27(35)28(25)29(33)21-13-15-31-16-14-21/h5-16,22,29,32H,17-18H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152225 (US8993552, 31) Show SMILES C1CN(CCN1c1nccs1)c1ncnc2sccc12 Show InChI InChI=1S/C13H13N5S2/c1-7-19-12-10(1)11(15-9-16-12)17-3-5-18(6-4-17)13-14-2-8-20-13/h1-2,7-9H,3-6H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	2.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152226 (US8993552, 60) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(Cc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C19H21ClN4S/c1-2-16-11-17-18(21-13-22-19(17)25-16)24-9-7-23(8-10-24)12-14-3-5-15(20)6-4-14/h3-6,11,13H,2,7-10,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152240 (US8993552, 75) Show SMILES CC(C)c1cc2c(ncnc2s1)N1CCCN(CC1)C1=NCC(C)(C)S1 |t:22| Show InChI InChI=1S/C19H27N5S2/c1-13(2)15-10-14-16(21-12-22-17(14)25-15)23-6-5-7-24(9-8-23)18-20-11-19(3,4)26-18/h10,12-13H,5-9,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152265 (US8993552, 6G10_3 Compound 47) Show SMILES COc1ccc(cc1)-c1csc(CC(N)=O)n1 Show InChI InChI=1S/C12H12N2O2S/c1-16-9-4-2-8(3-5-9)10-7-17-12(14-10)6-11(13)15/h2-5,7H,6H2,1H3,(H2,13,15)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152213 (US8993552, 3) Show SMILES C(CNc1ncnc2sc3CCCCCc3c12)Cn1ccnc1 Show InChI InChI=1S/C17H21N5S/c1-2-5-13-14(6-3-1)23-17-15(13)16(20-11-21-17)19-7-4-9-22-10-8-18-12-22/h8,10-12H,1-7,9H2,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152252 (US8993552, 35) Show SMILES COc1cc(cc(OC)c1OC)C1Nc2ccccc2NC2=C1C(=O)CC(C)(C)C2 |c:23| Show InChI InChI=1S/C24H28N2O4/c1-24(2)12-17-21(18(27)13-24)22(26-16-9-7-6-8-15(16)25-17)14-10-19(28-3)23(30-5)20(11-14)29-4/h6-11,22,25-26H,12-13H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152246 (US8993552, 81) Show SMILES CCc1cc2c(NCC3CCN(Cc4cccc(C)c4)CC3)ncnc2s1 Show InChI InChI=1S/C22H28N4S/c1-3-19-12-20-21(24-15-25-22(20)27-19)23-13-17-7-9-26(10-8-17)14-18-6-4-5-16(2)11-18/h4-6,11-12,15,17H,3,7-10,13-14H2,1-2H3,(H,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description NMR spectroscopy validation of lead compounds. In embodiments of the present invention, and during development thereof, NMR spectroscopy: saturation ...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152212 (US8993552, 2) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H22N4S/c1-2-16-12-17-18(20-14-21-19(17)24-16)23-10-8-22(9-11-23)13-15-6-4-3-5-7-15/h3-7,12,14H,2,8-11,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152219 (US8993552, 15) Show SMILES Cc1csc(n1)N1CCN(CC1)c1nc(C)nc2sc3CCCCc3c12 Show InChI InChI=1S/C19H23N5S2/c1-12-11-25-19(20-12)24-9-7-23(8-10-24)17-16-14-5-3-4-6-15(14)26-18(16)22-13(2)21-17/h11H,3-10H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152261 (US8993552, 4H8 Compound 42) Show SMILES Nc1cccc(c1)-c1cccnc1 Show InChI InChI=1S/C11H10N2/c12-11-5-1-3-9(7-11)10-4-2-6-13-8-10/h1-8H,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152222 (US8993552, 21) Show SMILES C1CN(CCN1c1nccs1)c1ncnc2sc(cc12)-c1ccccc1 Show InChI InChI=1S/C19H17N5S2/c1-2-4-14(5-3-1)16-12-15-17(21-13-22-18(15)26-16)23-7-9-24(10-8-23)19-20-6-11-25-19/h1-6,11-13H,7-10H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152214 (US8993552, 8) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C17H19N5S/c1-2-13-11-14-16(19-12-20-17(14)23-13)22-9-7-21(8-10-22)15-5-3-4-6-18-15/h3-6,11-12H,2,7-10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152253 (US8993552, 36) Show SMILES O=C1CC(CC2=C1C(Nc1ccccc1N2)c1cccnc1)c1ccc2OCOc2c1 |c:5| Show InChI InChI=1S/C25H21N3O3/c29-21-11-17(15-7-8-22-23(12-15)31-14-30-22)10-20-24(21)25(16-4-3-9-26-13-16)28-19-6-2-1-5-18(19)27-20/h1-9,12-13,17,25,27-28H,10-11,14H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152265 (US8993552, 6G10_3 Compound 47) Show SMILES COc1ccc(cc1)-c1csc(CC(N)=O)n1 Show InChI InChI=1S/C12H12N2O2S/c1-16-9-4-2-8(3-5-9)10-7-17-12(14-10)6-11(13)15/h2-5,7H,6H2,1H3,(H2,13,15)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152220 (US8993552, 16) Show SMILES Cc1c(sc2ncnc(N3CCN(CC3)c3nccs3)c12)-c1ccccc1 Show InChI InChI=1S/C20H19N5S2/c1-14-16-18(24-8-10-25(11-9-24)20-21-7-12-26-20)22-13-23-19(16)27-17(14)15-5-3-2-4-6-15/h2-7,12-13H,8-11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152258 (US8993552, 85) Show SMILES COc1ccc(cc1)C1CC(=O)C2=C(C1)Nc1ccccc1N(C2c1cccnc1)C(C)=O |c:13| Show InChI InChI=1S/C27H25N3O3/c1-17(31)30-24-8-4-3-7-22(24)29-23-14-20(18-9-11-21(33-2)12-10-18)15-25(32)26(23)27(30)19-6-5-13-28-16-19/h3-13,16,20,27,29H,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152272 (US8993552, 6G10_14 Compound 58) Show SMILES COc1ccc(cc1Br)-c1csc(CC(N)=O)n1 Show InChI InChI=1S/C12H11BrN2O2S/c1-17-10-3-2-7(4-8(10)13)9-6-18-12(15-9)5-11(14)16/h2-4,6H,5H2,1H3,(H2,14,16)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152213 (US8993552, 3) Show SMILES C(CNc1ncnc2sc3CCCCCc3c12)Cn1ccnc1 Show InChI InChI=1S/C17H21N5S/c1-2-5-13-14(6-3-1)23-17-15(13)16(20-11-21-17)19-7-4-9-22-10-8-18-12-22/h8,10-12H,1-7,9H2,(H,19,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152212 (US8993552, 2) Show SMILES CCc1cc2c(ncnc2s1)N1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H22N4S/c1-2-16-12-17-18(20-14-21-19(17)24-16)23-10-8-22(9-11-23)13-15-6-4-3-5-7-15/h3-7,12,14H,2,8-11,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description One potential limitation of the above FP assay is the risk of selection of compounds that may interfere with the FP assays and produce so called fals...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair
Menin (Homo sapiens (Human))	BDBM152257 (US8993552, 84) Show SMILES CC(=O)N1C(C2=C(CC(CC2=O)c2ccc(C)cc2)Nc2ccccc12)c1cccnc1 |t:5| Show InChI InChI=1S/C27H25N3O2/c1-17-9-11-19(12-10-17)21-14-23-26(25(32)15-21)27(20-6-5-13-28-16-20)30(18(2)31)24-8-4-3-7-22(24)29-23/h3-13,16,21,27,29H,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of The University of Michigan; University of Virginia Patent Foundation US Patent					Assay Description Assays effective in monitoring the inhibition of the MLL binding to menin were developed during experiments performed during the development of embod...				US Patent US8993552 (2015) BindingDB Entry DOI: 10.7270/Q2V123HF
					More data for this Ligand-Target Pair

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