Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152509 ((4-Bromo-2,5-dihydroxyphenyl)(4-hydroxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.78 | n/a | 4.58 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152510 ((4-Bromo-2,5-dihydroxyphenyl)(phenyl)methanone (23...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.24 | n/a | 4.88 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152500 ((2-bromo-4-methoxyphenyl)(3,4-dimethoxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.53 | n/a | 4.41 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152506 ((5-bromo-2,4-dimethoxyphenyl)(4-methoxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 3.65 | n/a | 4.05 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152508 ((2-Bromo-4-hydroxyphenyl)(2,3-dihydroxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.75 | n/a | 4.84 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152503 ((4-Bromo-2,5-dimethoxyphenyl)(4-methoxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.77 | n/a | 4.22 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152507 ((2-bromo-4-hydroxyphenyl)(3,4-dihydroxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.06 | n/a | 4.71 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152502 (2-bromo-1,4-dimethoxybenzene (14)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 4.25 | n/a | 7.21 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152501 ((2-Bromo-4-methoxyphenyl)(2,3-dimethoxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.34 | n/a | 4.20 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152504 ((4-Bromo-2,5-dimethoxyphenyl)(phenyl)methanone (16...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.28 | n/a | 4.68 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152511 ((5-Bromo-2,4-dihydroxyphenyl)(4-hydroxyphenyl)meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.72 | n/a | 4.81 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM152505 ((2,4-dimethoxyphenyl)(4-methoxyphenyl)methanone (1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | 5.88 | n/a | 5.25 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Homo sapiens (Human)) | BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 7.64 | n/a | 7.53 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Ataturk University | Assay Description AChI and 5,5'-dithio-bis(2-nitro-benzoic)acid (DTNB) were used as substrate for this enzymatic reaction. To this end, 100 無 of Tris/HCl buffer (... | Bioorg Chem 60: 49-57 (2015) Article DOI: 10.1016/j.bioorg.2015.04.006 BindingDB Entry DOI: 10.7270/Q2930RW6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |