Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rhomboid protease GlpG (Haemophilus influenzae (g-Proteobacteria)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 660 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Thermotoga maritima (Thermotogales)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Aquifex aeolicus (Aquificales)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Aquifex aeolicus (Aquificales)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GluP [F193S,L370F,L379S,R499W] (Bacillus subtilis (Firmicutes)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Haemophilus influenzae (g-Proteobacteria)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AN1-type domain-containing protein (Archaeoglobus fulgidus (AfROM)) | BDBM165195 ((4S)‐4‐(pent‐4‐yn‐1&...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
AN1-type domain-containing protein (Archaeoglobus fulgidus (AfROM)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease AarA (Providencia stuartii (Enterobacteria)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease AarA (Providencia stuartii (Enterobacteria)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Pyrococcus horikoshii (Euryarchaeotes)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid-related protein 3 (Mus musculus (Mouse)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Pyrococcus horikoshii (Euryarchaeotes)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GluP [F193S,L370F,L379S,R499W] (Bacillus subtilis (Firmicutes)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Thermotoga maritima (Thermotogales)) | BDBM165196 ((4S)‐4‐(pent‐4‐yn‐1&...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GlpG protein (Vibrio cholerae (g-Proteobacteria)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid-related protein 1 (Mus musculus (Mouse)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Thermotoga maritima (Thermotogales)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid-related protein 1 (Mus musculus (Mouse)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Escherichia coli (Enterobacteria)) | BDBM165197 ((4S)‐3‐butyl‐4‐(pent‐...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid domain-containing protein (Thermotoga maritima (Thermotogales)) | BDBM165197 ((4S)‐3‐butyl‐4‐(pent‐...) | KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid protease GlpG (Haemophilus influenzae (g-Proteobacteria)) | BDBM165195 ((4S)‐4‐(pent‐4‐yn‐1&...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rhomboid-related protein 3 (Mus musculus (Mouse)) | BDBM50199883 (3,4‐Dichloroisocoumarin (2) | 3,4-Dichloro-i...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents | Article PubMed | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GlpG protein (Vibrio cholerae (g-Proteobacteria)) | BDBM165194 (4‐Chloro‐7‐nitro‐3‐[...) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.60E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Technische Universität München | Assay Description We selected several inhibitor structures and determined their apparent IC50 by competitive ABPP. | ACS Chem Biol 10: 2325-33 (2015) Article DOI: 10.1021/acschembio.5b00514 BindingDB Entry DOI: 10.7270/Q2668BZ8 | |||||||||||
More data for this Ligand-Target Pair |