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Compile Data Set for Download or QSAR

Found 105 hits Enz. Inhib. hit(s) with all data for entry = 7039   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168025
PNG
(US9073926, 59)
Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2)c1 |r|
Show InChI InChI=1/C22H20N6O2/c1-14-10-23-22(30)19-9-16-7-8-18(26-20(16)28(14)19)21(29)25-17-11-24-27(13-17)12-15-5-3-2-4-6-15/h2-9,11,13-14H,10,12H2,1H3,(H,23,30)(H,25,29)/t14-/s2
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n/an/a 0.200n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168034
PNG
(US9073926, 68)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccncc2)c1
Show InChI InChI=1/C22H21N7O2/c1-14-4-9-24-22(31)19-10-16-2-3-18(27-20(16)29(14)19)21(30)26-17-11-25-28(13-17)12-15-5-7-23-8-6-15/h2-3,5-8,10-11,13-14H,4,9,12H2,1H3,(H,24,31)(H,26,30)
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n/an/a 0.270n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168027
PNG
(US9073926, 61)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(nc3n2[C@H]1C)C(=O)Nc1cnn(Cc2ccccc2)c1 |r|
Show InChI InChI=1/C23H22N6O2/c1-14-15(2)29-20(23(31)25-14)10-17-8-9-19(27-21(17)29)22(30)26-18-11-24-28(13-18)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H,25,31)(H,26,30)/t14-,15+/s2
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n/an/a 0.340n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168012
PNG
(US9073926, 46)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2)c1
Show InChI InChI=1/C23H22N6O2/c1-15-9-10-24-23(31)20-11-17-7-8-19(27-21(17)29(15)20)22(30)26-18-12-25-28(14-18)13-16-5-3-2-4-6-16/h2-8,11-12,14-15H,9-10,13H2,1H3,(H,24,31)(H,26,30)
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n/an/a 0.390n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168006
PNG
(US9073926, 40)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(C)c1
Show InChI InChI=1/C17H18N6O2/c1-10-5-6-18-17(25)14-7-11-3-4-13(21-15(11)23(10)14)16(24)20-12-8-19-22(2)9-12/h3-4,7-10H,5-6H2,1-2H3,(H,18,25)(H,20,24)
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n/an/a 0.780n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168009
PNG
(US9073926, 43)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(c1)C(C)(C)C
Show InChI InChI=1/C20H24N6O2/c1-12-7-8-21-19(28)16-9-13-5-6-15(24-17(13)26(12)16)18(27)23-14-10-22-25(11-14)20(2,3)4/h5-6,9-12H,7-8H2,1-4H3,(H,21,28)(H,23,27)
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n/an/a 1.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168070
PNG
(US9073926, 104)
Show SMILES Cn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)nc1C(=O)NC1CCCC1
Show InChI InChI=1S/C22H25N7O3/c1-28-12-17(26-19(28)22(32)24-14-5-2-3-6-14)27-20(30)15-8-7-13-11-16-21(31)23-9-4-10-29(16)18(13)25-15/h7-8,11-12,14H,2-6,9-10H2,1H3,(H,23,31)(H,24,32)(H,27,30)
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n/an/a 1.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168001
PNG
(US9073926, 35)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnc2n(CC3CCOC3)ncc2c1
Show InChI InChI=1/C24H25N7O3/c1-14-4-6-25-24(33)20-9-16-2-3-19(29-22(16)31(14)20)23(32)28-18-8-17-10-27-30(21(17)26-11-18)12-15-5-7-34-13-15/h2-3,8-11,14-15H,4-7,12-13H2,1H3,(H,25,33)(H,28,32)
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n/an/a 1.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167995
PNG
(US9073926, 29)
Show SMILES CC(C)n1ncc2cc(NC(=O)c3ccc4cc5C(=O)NCCC(C)n5c4n3)cnc12
Show InChI InChI=1/C22H23N7O2/c1-12(2)29-19-15(10-25-29)8-16(11-24-19)26-21(30)17-5-4-14-9-18-22(31)23-7-6-13(3)28(18)20(14)27-17/h4-5,8-13H,6-7H2,1-3H3,(H,23,31)(H,26,30)
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n/an/a 2.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167998
PNG
(US9073926, 32)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnc2n(ncc2c1)C1CCOCC1
Show InChI InChI=1/C24H25N7O3/c1-14-4-7-25-24(33)20-11-15-2-3-19(29-22(15)30(14)20)23(32)28-17-10-16-12-27-31(21(16)26-13-17)18-5-8-34-9-6-18/h2-3,10-14,18H,4-9H2,1H3,(H,25,33)(H,28,32)
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n/an/a 2.30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167992
PNG
(US9073926, 26)
Show SMILES NC(=O)c1ccccc1NC(=O)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C19H17N5O3/c20-16(25)12-4-1-2-5-13(12)23-18(26)14-7-6-11-10-15-19(27)21-8-3-9-24(15)17(11)22-14/h1-2,4-7,10H,3,8-9H2,(H2,20,25)(H,21,27)(H,23,26)
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n/an/a 2.30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168051
PNG
(US9073926, 85)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(nc3n2[C@H]1C)C(=O)Nc1cc(C)on1 |r|
Show InChI InChI=1/C17H17N5O3/c1-8-6-14(21-25-8)20-16(23)12-5-4-11-7-13-17(24)18-9(2)10(3)22(13)15(11)19-12/h4-7,9-10H,1-3H3,(H,18,24)(H,20,21,23)/t9-,10+/s2
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n/an/a 2.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168030
PNG
(US9073926, 64)
Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnc2ccccc2c1 |r|
Show InChI InChI=1/C21H17N5O2/c1-12-10-23-21(28)18-9-14-6-7-17(25-19(14)26(12)18)20(27)24-15-8-13-4-2-3-5-16(13)22-11-15/h2-9,11-12H,10H2,1H3,(H,23,28)(H,24,27)/t12-/s2
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n/an/a 3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168028
PNG
(US9073926, 62)
Show SMILES C[C@@H]1NC(=O)c2cc3ccc(nc3n2[C@H]1C)C(=O)Nc1cnn(Cc2ccccc2)c1 |r|
Show InChI InChI=1/C23H22N6O2/c1-14-15(2)29-20(23(31)25-14)10-17-8-9-19(27-21(17)29)22(30)26-18-11-24-28(13-18)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H,25,31)(H,26,30)/t14-,15-/s2
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n/an/a 3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168060
PNG
(US9073926, 94)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cc(Cc2ccccc2)on1
Show InChI InChI=1/C23H21N5O3/c1-14-9-10-24-23(30)19-12-16-7-8-18(25-21(16)28(14)19)22(29)26-20-13-17(31-27-20)11-15-5-3-2-4-6-15/h2-8,12-14H,9-11H2,1H3,(H,24,30)(H,26,27,29)
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n/an/a 3.30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168061
PNG
(US9073926, 95)
Show SMILES O=C(Nc1cc(Cc2ccccc2)no1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C22H19N5O3/c28-21(25-19-13-16(26-30-19)11-14-5-2-1-3-6-14)17-8-7-15-12-18-22(29)23-9-4-10-27(18)20(15)24-17/h1-3,5-8,12-13H,4,9-11H2,(H,23,29)(H,25,28)
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n/an/a 3.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168013
PNG
(US9073926, 47)
Show SMILES O=C(Nc1cnn(Cc2ccccc2)c1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C22H20N6O2/c29-21(25-17-12-24-27(14-17)13-15-5-2-1-3-6-15)18-8-7-16-11-19-22(30)23-9-4-10-28(19)20(16)26-18/h1-3,5-8,11-12,14H,4,9-10,13H2,(H,23,30)(H,25,29)
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n/an/a 3.80n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168004
PNG
(US9073926, 38)
Show SMILES Cc1ccnc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)c1
Show InChI InChI=1S/C18H17N5O2/c1-11-5-7-19-15(9-11)22-17(24)13-4-3-12-10-14-18(25)20-6-2-8-23(14)16(12)21-13/h3-5,7,9-10H,2,6,8H2,1H3,(H,20,25)(H,19,22,24)
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n/an/a 3.80n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168064
PNG
(US9073926, 98)
Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cc(Cc2ccccc2)on1 |r|
Show InChI InChI=1/C22H19N5O3/c1-13-12-23-22(29)18-10-15-7-8-17(24-20(15)27(13)18)21(28)25-19-11-16(30-26-19)9-14-5-3-2-4-6-14/h2-8,10-11,13H,9,12H2,1H3,(H,23,29)(H,25,26,28)/t13-/s2
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n/an/a 3.90n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168032
PNG
(US9073926, 66)
Show SMILES CC(C)n1ncc2cc(NC(=O)c3ccc4cc5C(=O)NC[C@@H](C)n5c4n3)cnc12 |r|
Show InChI InChI=1/C21H21N7O2/c1-11(2)28-18-14(9-24-28)6-15(10-22-18)25-20(29)16-5-4-13-7-17-21(30)23-8-12(3)27(17)19(13)26-16/h4-7,9-12H,8H2,1-3H3,(H,23,30)(H,25,29)/t12-/s2
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n/an/a 4n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168047
PNG
(US9073926, 81)
Show SMILES O=C(Nc1cc(no1)-c1ccccc1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C21H17N5O3/c27-20(24-18-12-16(25-29-18)13-5-2-1-3-6-13)15-8-7-14-11-17-21(28)22-9-4-10-26(17)19(14)23-15/h1-3,5-8,11-12H,4,9-10H2,(H,22,28)(H,24,27)
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n/an/a 4.30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167984
PNG
(US9073926, 18)
Show SMILES CC(C)n1c(NC(=O)c2ccc3nc4C(=O)NCCC(C)(C)n4c3c2)nc2ccccc12
Show InChI InChI=1S/C24H26N6O2/c1-14(2)29-18-8-6-5-7-16(18)27-23(29)28-21(31)15-9-10-17-19(13-15)30-20(26-17)22(32)25-12-11-24(30,3)4/h5-10,13-14H,11-12H2,1-4H3,(H,25,32)(H,27,28,31)
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n/an/a 4.70n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168007
PNG
(US9073926, 41)
Show SMILES Cn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)cn1
Show InChI InChI=1S/C16H16N6O2/c1-21-9-11(8-18-21)19-15(23)12-4-3-10-7-13-16(24)17-5-2-6-22(13)14(10)20-12/h3-4,7-9H,2,5-6H2,1H3,(H,17,24)(H,19,23)
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n/an/a 4.80n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168065
PNG
(US9073926, 99)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(nc3n2[C@H]1C)C(=O)Nc1cc(Cc2ccccc2)on1 |r|
Show InChI InChI=1/C23H21N5O3/c1-13-14(2)28-19(23(30)24-13)11-16-8-9-18(25-21(16)28)22(29)26-20-12-17(31-27-20)10-15-6-4-3-5-7-15/h3-9,11-14H,10H2,1-2H3,(H,24,30)(H,26,27,29)/t13-,14+/s2
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n/an/a 5.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168048
PNG
(US9073926, 82)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cc(C)on1
Show InChI InChI=1/C17H17N5O3/c1-9-5-6-18-17(24)13-8-11-3-4-12(19-15(11)22(9)13)16(23)20-14-7-10(2)25-21-14/h3-4,7-9H,5-6H2,1-2H3,(H,18,24)(H,20,21,23)
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n/an/a 5.20n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167969
PNG
(US9073926, 3)
Show SMILES CCn1c(NC(=O)c2ccc3nc4C(=O)NCCCn4c3c2)nc2ccccc12
Show InChI InChI=1S/C21H20N6O2/c1-2-26-16-7-4-3-6-14(16)24-21(26)25-19(28)13-8-9-15-17(12-13)27-11-5-10-22-20(29)18(27)23-15/h3-4,6-9,12H,2,5,10-11H2,1H3,(H,22,29)(H,24,25,28)
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n/an/a 5.5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168033
PNG
(US9073926, 67)
Show SMILES Clc1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4n3)nc2c1
Show InChI InChI=1S/C19H15ClN6O2/c20-11-3-5-12-14(9-11)24-19(23-12)25-17(27)13-4-2-10-8-15-18(28)21-6-1-7-26(15)16(10)22-13/h2-5,8-9H,1,6-7H2,(H,21,28)(H2,23,24,25,27)
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n/an/a 6.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168050
PNG
(US9073926, 84)
Show SMILES C[C@@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cc(C)on1 |r|
Show InChI InChI=1/C16H15N5O3/c1-8-7-17-16(23)12-6-10-3-4-11(18-14(10)21(8)12)15(22)19-13-5-9(2)24-20-13/h3-6,8H,7H2,1-2H3,(H,17,23)(H,19,20,22)/t8-/s2
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n/an/a 6.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168015
PNG
(US9073926, 49)
Show SMILES Clc1cc(CN2CCOCC2)c2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4n3)nc2c1
Show InChI InChI=1S/C24H24ClN7O3/c25-16-10-15(13-31-6-8-35-9-7-31)20-18(12-16)28-24(29-20)30-22(33)17-3-2-14-11-19-23(34)26-4-1-5-32(19)21(14)27-17/h2-3,10-12H,1,4-9,13H2,(H,26,34)(H2,28,29,30,33)
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n/an/a 6.70n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167989
PNG
(US9073926, 23)
Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C21H17N5O2/c27-20(24-15-10-13-4-1-2-5-16(13)23-12-15)17-7-6-14-11-18-21(28)22-8-3-9-26(18)19(14)25-17/h1-2,4-7,10-12H,3,8-9H2,(H,22,28)(H,24,27)
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n/an/a 9.20n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168010
PNG
(US9073926, 44)
Show SMILES CC(C)(C)n1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)cn1
Show InChI InChI=1S/C19H22N6O2/c1-19(2,3)25-11-13(10-21-25)22-17(26)14-6-5-12-9-15-18(27)20-7-4-8-24(15)16(12)23-14/h5-6,9-11H,4,7-8H2,1-3H3,(H,20,27)(H,22,26)
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n/an/a 9.70n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168039
PNG
(US9073926, 73)
Show SMILES CCn1c(NC(=O)c2ccc3cc4C(=O)N[C@H](C)[C@H](C)n4c3n2)nc2ccccc12 |r|
Show InChI InChI=1/C22H22N6O2/c1-4-27-17-8-6-5-7-15(17)25-22(27)26-20(29)16-10-9-14-11-18-21(30)23-12(2)13(3)28(18)19(14)24-16/h5-13H,4H2,1-3H3,(H,23,30)(H,25,26,29)/t12-,13+/s2
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n/an/a 11.6n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168014
PNG
(US9073926, 48)
Show SMILES CC1(C)CNC(=O)c2cc3ccc(nc3n2C1)C(=O)Nc1cnn(Cc2ccccc2)c1
Show InChI InChI=1S/C24H24N6O2/c1-24(2)14-25-23(32)20-10-17-8-9-19(28-21(17)30(20)15-24)22(31)27-18-11-26-29(13-18)12-16-6-4-3-5-7-16/h3-11,13H,12,14-15H2,1-2H3,(H,25,32)(H,27,31)
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n/an/a 12n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168026
PNG
(US9073926, 60)
Show SMILES C[C@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnn(Cc2ccccc2)c1 |r|
Show InChI InChI=1/C22H20N6O2/c1-14-10-23-22(30)19-9-16-7-8-18(26-20(16)28(14)19)21(29)25-17-11-24-27(13-17)12-15-5-3-2-4-6-15/h2-9,11,13-14H,10,12H2,1H3,(H,23,30)(H,25,29)/t14-/s2
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n/an/a 12n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168062
PNG
(US9073926, 96)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cc(Cc2ccccc2)no1
Show InChI InChI=1/C23H21N5O3/c1-14-9-10-24-23(30)19-12-16-7-8-18(25-21(16)28(14)19)22(29)26-20-13-17(27-31-20)11-15-5-3-2-4-6-15/h2-8,12-14H,9-11H2,1H3,(H,24,30)(H,26,29)
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n/an/a 13n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168002
PNG
(US9073926, 36)
Show SMILES O=C(Nc1cnc2n(CC3CCOC3)ncc2c1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1/C23H23N7O3/c31-22(18-3-2-15-9-19-23(32)24-5-1-6-29(19)21(15)28-18)27-17-8-16-10-26-30(20(16)25-11-17)12-14-4-7-33-13-14/h2-3,8-11,14H,1,4-7,12-13H2,(H,24,32)(H,27,31)
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n/an/a 13n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168035
PNG
(US9073926, 69)
Show SMILES CCn1c(NC(=O)c2ccc3cc4C(=O)NCCC(C)n4c3n2)nc2ccccc12
Show InChI InChI=1/C22H22N6O2/c1-3-27-17-7-5-4-6-15(17)25-22(27)26-20(29)16-9-8-14-12-18-21(30)23-11-10-13(2)28(18)19(14)24-16/h4-9,12-13H,3,10-11H2,1-2H3,(H,23,30)(H,25,26,29)
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n/an/a 15n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168071
PNG
(US9073926, 105)
Show SMILES O=C(Nc1cccc(c1)-c1c[nH]cn1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C21H18N6O2/c28-20(25-15-4-1-3-13(9-15)17-11-22-12-24-17)16-6-5-14-10-18-21(29)23-7-2-8-27(18)19(14)26-16/h1,3-6,9-12H,2,7-8H2,(H,22,24)(H,23,29)(H,25,28)
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n/an/a 17n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168046
PNG
(US9073926, 80)
Show SMILES Cc1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)no1
Show InChI InChI=1S/C16H15N5O3/c1-9-7-13(20-24-9)19-15(22)11-4-3-10-8-12-16(23)17-5-2-6-21(12)14(10)18-11/h3-4,7-8H,2,5-6H2,1H3,(H,17,23)(H,19,20,22)
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n/an/a 19n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168045
PNG
(US9073926, 79)
Show SMILES CC(C)(C)c1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)no1
Show InChI InChI=1S/C19H21N5O3/c1-19(2,3)14-10-15(23-27-14)22-17(25)12-6-5-11-9-13-18(26)20-7-4-8-24(13)16(11)21-12/h5-6,9-10H,4,7-8H2,1-3H3,(H,20,26)(H,22,23,25)
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n/an/a 19n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167991
PNG
(US9073926, 25)
Show SMILES Fc1cccc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)c1
Show InChI InChI=1S/C18H15FN4O2/c19-12-3-1-4-13(10-12)21-17(24)14-6-5-11-9-15-18(25)20-7-2-8-23(15)16(11)22-14/h1,3-6,9-10H,2,7-8H2,(H,20,25)(H,21,24)
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n/an/a 20n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167999
PNG
(US9073926, 33)
Show SMILES O=C(Nc1cnc2n(ncc2c1)C1CCOCC1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C23H23N7O3/c31-22(18-3-2-14-11-19-23(32)24-6-1-7-29(19)21(14)28-18)27-16-10-15-12-26-30(20(15)25-13-16)17-4-8-33-9-5-17/h2-3,10-13,17H,1,4-9H2,(H,24,32)(H,27,31)
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n/an/a 20n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167983
PNG
(US9073926, 17)
Show SMILES CCn1c(NC(=O)c2ccc3nc4C(=O)NCCCn4c3c2)nc2cccnc12
Show InChI InChI=1S/C20H19N7O2/c1-2-26-16-14(5-3-8-21-16)24-20(26)25-18(28)12-6-7-13-15(11-12)27-10-4-9-22-19(29)17(27)23-13/h3,5-8,11H,2,4,9-10H2,1H3,(H,22,29)(H,24,25,28)
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n/an/a 23n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167996
PNG
(US9073926, 30)
Show SMILES CC(C)n1ncc2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4n3)cnc12
Show InChI InChI=1S/C21H21N7O2/c1-12(2)28-18-14(10-24-28)8-15(11-23-18)25-20(29)16-5-4-13-9-17-21(30)22-6-3-7-27(17)19(13)26-16/h4-5,8-12H,3,6-7H2,1-2H3,(H,22,30)(H,25,29)
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n/an/a 25n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168003
PNG
(US9073926, 37)
Show SMILES CC1(C)CNC(=O)c2cc3ccc(nc3n2C1)C(=O)Nc1cnc2n(CC3CCOC3)ncc2c1
Show InChI InChI=1/C25H27N7O3/c1-25(2)13-27-24(34)20-8-16-3-4-19(30-22(16)31(20)14-25)23(33)29-18-7-17-9-28-32(21(17)26-10-18)11-15-5-6-35-12-15/h3-4,7-10,15H,5-6,11-14H2,1-2H3,(H,27,34)(H,29,33)
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n/an/a 25n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168038
PNG
(US9073926, 72)
Show SMILES CCn1c(NC(=O)c2ccc3cc4C(=O)NC[C@@H](C)n4c3n2)nc2ccccc12 |r|
Show InChI InChI=1/C21H20N6O2/c1-3-26-16-7-5-4-6-14(16)24-21(26)25-19(28)15-9-8-13-10-17-20(29)22-11-12(2)27(17)18(13)23-15/h4-10,12H,3,11H2,1-2H3,(H,22,29)(H,24,25,28)/t12-/s2
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n/an/a 26.5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168036
PNG
(US9073926, 70)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1nc2ccccc2n1CCCN(C)C
Show InChI InChI=1/C25H29N7O2/c1-16-11-12-26-24(34)21-15-17-9-10-19(27-22(17)32(16)21)23(33)29-25-28-18-7-4-5-8-20(18)31(25)14-6-13-30(2)3/h4-5,7-10,15-16H,6,11-14H2,1-3H3,(H,26,34)(H,28,29,33)
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n/an/a 27n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168043
PNG
(US9073926, 77)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(nc3n2[C@H]1C)C(=O)Nc1nc2ccccc2n1CCCN(C)C |r|
Show InChI InChI=1/C25H29N7O2/c1-15-16(2)32-21(24(34)26-15)14-17-10-11-19(27-22(17)32)23(33)29-25-28-18-8-5-6-9-20(18)31(25)13-7-12-30(3)4/h5-6,8-11,14-16H,7,12-13H2,1-4H3,(H,26,34)(H,28,29,33)/t15-,16+/s2
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n/an/a 29n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM167970
PNG
(US9073926, 4)
Show SMILES CC(C)n1c(NC(=O)c2ccc3nc4C(=O)NCCCn4c3c2)nc2ccccc12
Show InChI InChI=1S/C22H22N6O2/c1-13(2)28-17-7-4-3-6-15(17)25-22(28)26-20(29)14-8-9-16-18(12-14)27-11-5-10-23-21(30)19(27)24-16/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,23,30)(H,25,26,29)
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n/an/a 33n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168031
PNG
(US9073926, 65)
Show SMILES C[C@H]1CNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cnc2ccccc2c1 |r|
Show InChI InChI=1/C21H17N5O2/c1-12-10-23-21(28)18-9-14-6-7-17(25-19(14)26(12)18)20(27)24-15-8-13-4-2-3-5-16(13)22-11-15/h2-9,11-12H,10H2,1H3,(H,23,28)(H,24,27)/t12-/s2
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n/an/a 34n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair
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