Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with all data for entry = 7073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172726 (US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...) Show SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172721 (US9096515, 21a | US9296681, 21a) Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H30Cl2N2O2/c1-4-26-19(25)24-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172725 (US9096515, 33a -Racemic) Show SMILES CC(CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172722 (US9096515, 21b | US9296681, 21b) Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1 Show InChI InChI=1S/C22H36N2O3/c1-5-26-19-10-8-18(9-11-19)22(12-7-13-22)20(16-17(3)4)23-14-15-24-21(25)27-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172726 (US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...) Show SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) Show SMILES CCOc1ccc(cc1)C1(C[C@@H](C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172728 (US9096515, 33b -Racemic | US9296681, 33b-Racemic) Show SMILES CCOc1ccc(cc1)C1(CC(C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172720 (US9096515, 12u | US9296681, 12u) Show SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCOC(=O)CC Show InChI InChI=1S/C22H35NO3/c1-5-21(24)26-15-14-23-20(16-17(3)4)22(12-7-13-22)18-8-10-19(11-9-18)25-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172719 (US9096515, 12q | US9296681, 12q) Show SMILES CCC(=O)OCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H29Cl2NO2/c1-4-19(24)25-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172725 (US9096515, 33a -Racemic) Show SMILES CC(CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172719 (US9096515, 12q | US9296681, 12q) Show SMILES CCC(=O)OCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H29Cl2NO2/c1-4-19(24)25-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172721 (US9096515, 21a | US9296681, 21a) Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H30Cl2N2O2/c1-4-26-19(25)24-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172724 (US9096515, 31b | US9296681, 31b) Show SMILES CCCC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1 Show InChI InChI=1S/C23H38N2O2/c1-5-8-22(26)25-16-15-24-21(17-18(3)4)23(13-7-14-23)19-9-11-20(12-10-19)27-6-2/h9-12,18,21,24H,5-8,13-17H2,1-4H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172723 (US9096515, 31a | US9296681, 31a) Show SMILES CCCC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H32Cl2N2O/c1-4-6-20(26)25-12-11-24-19(13-15(2)3)21(9-5-10-21)16-7-8-17(22)18(23)14-16/h7-8,14-15,19,24H,4-6,9-13H2,1-3H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	27.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172726 (US9096515, 33a -(R)-Isomer | US9296681, 33a-(R)-Is...) Show SMILES C[C@@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	30.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172719 (US9096515, 12q | US9296681, 12q) Show SMILES CCC(=O)OCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H29Cl2NO2/c1-4-19(24)25-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	38.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172721 (US9096515, 21a | US9296681, 21a) Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H30Cl2N2O2/c1-4-26-19(25)24-11-10-23-18(12-14(2)3)20(8-5-9-20)15-6-7-16(21)17(22)13-15/h6-7,13-14,18,23H,4-5,8-12H2,1-3H3,(H,24,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	38.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172725 (US9096515, 33a -Racemic) Show SMILES CC(CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	50.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172723 (US9096515, 31a | US9296681, 31a) Show SMILES CCCC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H32Cl2N2O/c1-4-6-20(26)25-12-11-24-19(13-15(2)3)21(9-5-10-21)16-7-8-17(22)18(23)14-16/h7-8,14-15,19,24H,4-6,9-13H2,1-3H3,(H,25,26)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	52.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172723 (US9096515, 31a | US9296681, 31a) Show SMILES CCCC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C21H32Cl2N2O/c1-4-6-20(26)25-12-11-24-19(13-15(2)3)21(9-5-10-21)16-7-8-17(22)18(23)14-16/h7-8,14-15,19,24H,4-6,9-13H2,1-3H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	77.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172720 (US9096515, 12u | US9296681, 12u) Show SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCOC(=O)CC Show InChI InChI=1S/C22H35NO3/c1-5-21(24)26-15-14-23-20(16-17(3)4)22(12-7-13-22)18-8-10-19(11-9-18)25-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	80.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172727 (US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...) Show SMILES C[C@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) Show SMILES CCOc1ccc(cc1)C1(C[C@@H](C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m0/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172722 (US9096515, 21b | US9296681, 21b) Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1 Show InChI InChI=1S/C22H36N2O3/c1-5-26-19-10-8-18(9-11-19)22(12-7-13-22)20(16-17(3)4)23-14-15-24-21(25)27-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3,(H,24,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	159	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172724 (US9096515, 31b | US9296681, 31b) Show SMILES CCCC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1 Show InChI InChI=1S/C23H38N2O2/c1-5-8-22(26)25-16-15-24-21(17-18(3)4)23(13-7-14-23)19-9-11-20(12-10-19)27-6-2/h9-12,18,21,24H,5-8,13-17H2,1-4H3,(H,25,26)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172727 (US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...) Show SMILES C[C@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172730 (US9096515, 33b -(S)-Isomer | US9296681, 33b-(S)-Is...) Show SMILES CCOc1ccc(cc1)C1(C[C@H](C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	329	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172728 (US9096515, 33b -Racemic | US9296681, 33b-Racemic) Show SMILES CCOc1ccc(cc1)C1(CC(C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	472	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172730 (US9096515, 33b -(S)-Isomer | US9296681, 33b-(S)-Is...) Show SMILES CCOc1ccc(cc1)C1(C[C@H](C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172722 (US9096515, 21b | US9296681, 21b) Show SMILES CCOC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1 Show InChI InChI=1S/C22H36N2O3/c1-5-26-19-10-8-18(9-11-19)22(12-7-13-22)20(16-17(3)4)23-14-15-24-21(25)27-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3,(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172720 (US9096515, 12u | US9296681, 12u) Show SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCOC(=O)CC Show InChI InChI=1S/C22H35NO3/c1-5-21(24)26-15-14-23-20(16-17(3)4)22(12-7-13-22)18-8-10-19(11-9-18)25-6-2/h8-11,17,20,23H,5-7,12-16H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172727 (US9096515, 33a -(S)-Isomer | US9296681, 33a-(S)-Is...) Show SMILES C[C@H](CCNCCCC(N)=O)CC1(CCC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H28Cl2N2O/c1-14(7-11-23-10-2-4-18(22)24)13-19(8-3-9-19)15-5-6-16(20)17(21)12-15/h5-6,12,14,23H,2-4,7-11,13H2,1H3,(H2,22,24)/t14-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM172730 (US9096515, 33b -(S)-Isomer | US9296681, 33b-(S)-Is...) Show SMILES CCOc1ccc(cc1)C1(C[C@H](C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m1/s1	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172724 (US9096515, 31b | US9296681, 31b) Show SMILES CCCC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1 Show InChI InChI=1S/C23H38N2O2/c1-5-8-22(26)25-16-15-24-21(17-18(3)4)23(13-7-14-23)19-9-11-20(12-10-19)27-6-2/h9-12,18,21,24H,5-8,13-17H2,1-4H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172729 (US9096515, 33b -(R)-Isomer | US9296681, 33b-(R)-Is...) Show SMILES CCOc1ccc(cc1)C1(C[C@@H](C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)/t17-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.52E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM172728 (US9096515, 33b -Racemic | US9296681, 33b-Racemic) Show SMILES CCOc1ccc(cc1)C1(CC(C)CCNCCCC(N)=O)CCC1 Show InChI InChI=1S/C21H34N2O2/c1-3-25-19-9-7-18(8-10-19)21(12-5-13-21)16-17(2)11-15-23-14-4-6-20(22)24/h7-10,17,23H,3-6,11-16H2,1-2H3,(H2,22,24)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
REVIVA PHARMACEUTICALS, INC. US Patent					Assay Description The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...				US Patent US9096515 (2015) BindingDB Entry DOI: 10.7270/Q2Z60MTK
					More data for this Ligand-Target Pair