Compile Data Set for Download or QSAR

Found 63 hits Enz. Inhib. hit(s) with all data for entry = 7133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176564 (US9120756, 26) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-6-7-18(17(23)8-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-5-3-4-14(22)9-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-59.4	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176555 (US9120756, 17) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-9-10-21(20(26)11-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-8-6-7-17(25)12-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-59.4	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176555 (US9120756, 17) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-9-10-21(20(26)11-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-8-6-7-17(25)12-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176564 (US9120756, 26) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-6-7-18(17(23)8-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-5-3-4-14(22)9-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176554 (US9120756, 16) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-9-10-21(20(26)11-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-8-6-7-17(25)12-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176554 (US9120756, 16) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-9-10-21(20(26)11-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-8-6-7-17(25)12-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176559 (US9120756, 21) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-3-8-18(17(23)9-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-6-4-14(22)5-7-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176561 (US9120756, 23) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-3-8-18(17(23)9-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-6-4-14(22)5-7-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176562 (US9120756, 24) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-6-7-18(17(23)8-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-5-3-4-14(22)9-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-56.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176549 (US9120756, 7) Show SMILES CC(C(=O)NCc1cc(nn1C1CCCCC1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H35FN4O3S/c1-16(17-11-12-21(20(25)13-17)28-33(5,31)32)23(30)26-15-19-14-22(24(2,3)4)27-29(19)18-9-7-6-8-10-18/h11-14,16,18,28H,6-10,15H2,1-5H3,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176561 (US9120756, 23) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-3-8-18(17(23)9-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-6-4-14(22)5-7-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176562 (US9120756, 24) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-6-7-18(17(23)8-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-5-3-4-14(22)9-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176566 (US9120756, 28) Show SMILES COc1cc(ccc1NS(C)(=O)=O)C(C)C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F Show InChI InChI=1S/C22H22ClF3N4O4S/c1-13(14-7-8-18(19(9-14)34-2)29-35(3,32)33)21(31)27-12-17-11-20(22(24,25)26)28-30(17)16-6-4-5-15(23)10-16/h4-11,13,29H,12H2,1-3H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-55.8	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176556 (US9120756, 18) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(F)c(Cl)c1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H27ClF2N4O3S/c1-14(15-6-9-21(20(27)10-15)30-35(5,33)34)23(32)28-13-17-12-22(24(2,3)4)29-31(17)16-7-8-19(26)18(25)11-16/h6-12,14,30H,13H2,1-5H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-55.2	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176571 (US9120756, 40) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(cc1)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C27H21ClF4N4O2/c1-16(17-5-7-18(8-6-17)26(38)34-21-11-9-20(29)10-12-21)25(37)33-15-23-14-24(27(30,31)32)35-36(23)22-4-2-3-19(28)13-22/h2-14,16H,15H2,1H3,(H,33,37)(H,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.800	-54.0	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176559 (US9120756, 21) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-3-8-18(17(23)9-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-6-4-14(22)5-7-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176565 (US9120756, 27) Show SMILES COc1cc(ccc1NS(C)(=O)=O)C(C)C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C Show InChI InChI=1S/C25H31ClN4O4S/c1-16(17-10-11-21(22(12-17)34-5)29-35(6,32)33)24(31)27-15-20-14-23(25(2,3)4)28-30(20)19-9-7-8-18(26)13-19/h7-14,16,29H,15H2,1-6H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176567 (US9120756, 29) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C)c1cc(F)c(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H27ClF2N4O3S/c1-14(15-9-19(26)22(20(27)10-15)30-35(5,33)34)23(32)28-13-18-12-21(24(2,3)4)29-31(18)17-8-6-7-16(25)11-17/h6-12,14,30H,13H2,1-5H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	-53.0	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176553 (US9120756, 15) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-6-11-21(20(26)12-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-9-7-17(25)8-10-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.10	-51.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176565 (US9120756, 27) Show SMILES COc1cc(ccc1NS(C)(=O)=O)C(C)C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C Show InChI InChI=1S/C25H31ClN4O4S/c1-16(17-10-11-21(22(12-17)34-5)29-35(6,32)33)24(31)27-15-20-14-23(25(2,3)4)28-30(20)19-9-7-8-18(26)13-19/h7-14,16,29H,15H2,1-6H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.20	-51.4	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176583 (US9120756, 134) Show SMILES CC(C(=O)NCc1c(C)c(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(CNS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C23H23ClF4N4O3S/c1-13(15-7-8-16(19(25)9-15)11-30-36(3,34)35)22(33)29-12-20-14(2)21(23(26,27)28)31-32(20)18-6-4-5-17(24)10-18/h4-10,13,30H,11-12H2,1-3H3,(H,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	-51.1	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176553 (US9120756, 15) Show SMILES C[C@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-6-11-21(20(26)12-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-9-7-17(25)8-10-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176552 (US9120756, 14) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-6-11-21(20(26)12-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-9-7-17(25)8-10-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.70	-50.1	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176569 (US9120756, 33) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(C)(C)C)c1ccc(CNS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C25H30ClFN4O3S/c1-16(17-9-10-18(22(27)11-17)14-29-35(5,33)34)24(32)28-15-21-13-23(25(2,3)4)30-31(21)20-8-6-7-19(26)12-20/h6-13,16,29H,14-15H2,1-5H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-49.9	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176563 (US9120756, 25) Show SMILES C[C@@H](C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-6-7-18(17(23)8-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-5-3-4-14(22)9-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176550 (US9120756, 12) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(C)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C25H31FN4O3S/c1-16-7-10-19(11-8-16)30-20(14-23(28-30)25(3,4)5)15-27-24(31)17(2)18-9-12-22(21(26)13-18)29-34(6,32)33/h7-14,17,29H,15H2,1-6H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176568 (US9120756, 30) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1cc(F)cc(F)c1 Show InChI InChI=1S/C20H15ClF5N3O/c1-11(12-5-14(22)8-15(23)6-12)19(30)27-10-17-9-18(20(24,25)26)28-29(17)16-4-2-3-13(21)7-16/h2-9,11H,10H2,1H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	-48.7	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176552 (US9120756, 14) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H28ClFN4O3S/c1-15(16-6-11-21(20(26)12-16)29-34(5,32)33)23(31)27-14-19-13-22(24(2,3)4)28-30(19)18-9-7-17(25)8-10-18/h6-13,15,29H,14H2,1-5H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176570 (US9120756, 39) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(C(=O)Nc2ccccc2)c(F)c1 Show InChI InChI=1S/C27H21ClF4N4O2/c1-16(17-10-11-22(23(29)12-17)26(38)34-19-7-3-2-4-8-19)25(37)33-15-21-14-24(27(30,31)32)35-36(21)20-9-5-6-18(28)13-20/h2-14,16H,15H2,1H3,(H,33,37)(H,34,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.20	-48.3	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176550 (US9120756, 12) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(C)cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C25H31FN4O3S/c1-16-7-10-19(11-8-16)30-20(14-23(28-30)25(3,4)5)15-27-24(31)17(2)18-9-12-22(21(26)13-18)29-34(6,32)33/h7-14,17,29H,15H2,1-6H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8	-48.1	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176585 (US9120756, 141) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C21H15ClF7N3O/c1-11(12-5-6-16(17(23)7-12)20(24,25)26)19(33)30-10-15-9-18(21(27,28)29)31-32(15)14-4-2-3-13(22)8-14/h2-9,11H,10H2,1H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	13.6	-46.7	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176548 (US9120756, 6) Show SMILES CCCCCCn1nc(cc1CNC(=O)[C@@H](C)c1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C24H37FN4O3S/c1-7-8-9-10-13-29-19(15-22(27-29)24(3,4)5)16-26-23(30)17(2)18-11-12-21(20(25)14-18)28-33(6,31)32/h11-12,14-15,17,28H,7-10,13,16H2,1-6H3,(H,26,30)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176580 (US9120756, 128) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C1CC1)c1ccc(CS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H25ClFN3O3S/c1-15(17-8-9-18(22(26)10-17)14-33(2,31)32)24(30)27-13-21-12-23(16-6-7-16)28-29(21)20-5-3-4-19(25)11-20/h3-5,8-12,15-16H,6-7,13-14H2,1-2H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	16.3	-46.2	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176573 (US9120756, 47) Show SMILES COc1c(F)cc(cc1F)C(C)C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F Show InChI InChI=1S/C21H17ClF5N3O2/c1-11(12-6-16(23)19(32-2)17(24)7-12)20(31)28-10-15-9-18(21(25,26)27)29-30(15)14-5-3-4-13(22)8-14/h3-9,11H,10H2,1-2H3,(H,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	-46.1	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176549 (US9120756, 7) Show SMILES CC(C(=O)NCc1cc(nn1C1CCCCC1)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H35FN4O3S/c1-16(17-11-12-21(20(25)13-17)28-33(5,31)32)23(30)26-15-19-14-22(24(2,3)4)27-29(19)18-9-7-6-8-10-18/h11-14,16,18,28H,6-10,15H2,1-5H3,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	21.6	-45.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176585 (US9120756, 141) Show SMILES CC(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(c(F)c1)C(F)(F)F Show InChI InChI=1S/C21H15ClF7N3O/c1-11(12-5-6-16(17(23)7-12)20(24,25)26)19(33)30-10-15-9-18(21(27,28)29)31-32(15)14-4-2-3-13(22)8-14/h2-9,11H,10H2,1H3,(H,30,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176551 (US9120756, 13) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(cc1)C(C)(C)C)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C28H37FN4O3S/c1-18(19-9-14-24(23(29)15-19)32-37(8,35)36)26(34)30-17-22-16-25(28(5,6)7)31-33(22)21-12-10-20(11-13-21)27(2,3)4/h9-16,18,32H,17H2,1-8H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176586 (US9120756, 147) Show SMILES Oc1c(F)cc(CC(=O)NCc2cc(nn2-c2cccc(Cl)c2)C(F)(F)F)cc1F Show InChI InChI=1S/C19H13ClF5N3O2/c20-11-2-1-3-12(7-11)28-13(8-16(27-28)19(23,24)25)9-26-17(29)6-10-4-14(21)18(30)15(22)5-10/h1-5,7-8,30H,6,9H2,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	26	-45.0	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176563 (US9120756, 25) Show SMILES C[C@@H](C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-6-7-18(17(23)8-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-5-3-4-14(22)9-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	26.5	-45.0	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176548 (US9120756, 6) Show SMILES CCCCCCn1nc(cc1CNC(=O)[C@@H](C)c1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C24H37FN4O3S/c1-7-8-9-10-13-29-19(15-22(27-29)24(3,4)5)16-26-23(30)17(2)18-11-12-21(20(25)14-18)28-33(6,31)32/h11-12,14-15,17,28H,7-10,13,16H2,1-6H3,(H,26,30)/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	27.7	-44.9	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176578 (US9120756, 126) Show SMILES Fc1cc(NC(=O)NCc2cc(nn2-c2cccc(Cl)c2)C(F)(F)F)ccc1C1CC1 Show InChI InChI=1S/C21H17ClF4N4O/c22-13-2-1-3-15(8-13)30-16(10-19(29-30)21(24,25)26)11-27-20(31)28-14-6-7-17(12-4-5-12)18(23)9-14/h1-3,6-10,12H,4-5,11H2,(H2,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	31.4	-44.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176560 (US9120756, 22) Show SMILES C[C@@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-3-8-18(17(23)9-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-6-4-14(22)5-7-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	31.7	-44.5	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rattus norvegicus (rat))	BDBM176560 (US9120756, 22) Show SMILES C[C@@H](C(=O)NCc1cc(nn1-c1ccc(Cl)cc1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C21H19ClF4N4O3S/c1-12(13-3-8-18(17(23)9-13)29-34(2,32)33)20(31)27-11-16-10-19(21(24,25)26)28-30(16)15-6-4-14(22)5-7-15/h3-10,12,29H,11H2,1-2H3,(H,27,31)/t12-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	42.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the rat-species vanilloid receptor 1 (VR1/TRPV1) can be determined using the f...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176547 (US9120756, 5) Show SMILES CCCCCCn1nc(cc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1)C(C)(C)C Show InChI InChI=1S/C24H37FN4O3S/c1-7-8-9-10-13-29-19(15-22(27-29)24(3,4)5)16-26-23(30)17(2)18-11-12-21(20(25)14-18)28-33(6,31)32/h11-12,14-15,17,28H,7-10,13,16H2,1-6H3,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	50.2	-43.3	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176575 (US9120756, 74) Show SMILES Fc1cccc(CC(=O)NCc2cc(nn2-c2cccc(Cl)c2)C(F)(F)F)c1 Show InChI InChI=1S/C19H14ClF4N3O/c20-13-4-2-6-15(9-13)27-16(10-17(26-27)19(22,23)24)11-25-18(28)8-12-3-1-5-14(21)7-12/h1-7,9-10H,8,11H2,(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	51.8	-43.3	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176576 (US9120756, 117) Show SMILES CC(C)(C(=O)NCc1cc(nn1-c1cccc(Cl)c1)C(F)(F)F)c1cccc(F)c1 Show InChI InChI=1S/C21H18ClF4N3O/c1-20(2,13-5-3-7-15(23)9-13)19(30)27-12-17-11-18(21(24,25)26)28-29(17)16-8-4-6-14(22)10-16/h3-11H,12H2,1-2H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	56	-43.1	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176579 (US9120756, 127) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccccn1)C(C)(C)C)c1ccc(CNS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C24H30FN5O3S/c1-16(17-9-10-18(20(25)12-17)14-28-34(5,32)33)23(31)27-15-19-13-21(24(2,3)4)29-30(19)22-8-6-7-11-26-22/h6-13,16,28H,14-15H2,1-5H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	58.1	-43.0	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176581 (US9120756, 129) Show SMILES CC(C(=O)NCc1cc(nn1NCc1ccccn1)C(F)(F)F)c1ccc(CNS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C22H24F4N6O3S/c1-14(15-6-7-16(19(23)9-15)11-30-36(2,34)35)21(33)28-13-18-10-20(22(24,25)26)31-32(18)29-12-17-5-3-4-8-27-17/h3-10,14,29-30H,11-13H2,1-2H3,(H,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	63.6	-42.7	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176584 (US9120756, 137) Show SMILES CC(C(=O)NCc1cc(nn1C1CCCCC1)C(F)(F)F)c1ccc(CNS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C22H28F4N4O3S/c1-14(15-8-9-16(19(23)10-15)12-28-34(2,32)33)21(31)27-13-18-11-20(22(24,25)26)29-30(18)17-6-4-3-5-7-17/h8-11,14,17,28H,3-7,12-13H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	65.1	-42.7	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM176551 (US9120756, 13) Show SMILES CC(C(=O)NCc1cc(nn1-c1ccc(cc1)C(C)(C)C)C(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C28H37FN4O3S/c1-18(19-9-14-24(23(29)15-19)32-37(8,35)36)26(34)30-17-22-16-25(28(5,6)7)31-33(22)21-12-10-20(11-13-21)27(2,3)4/h9-16,18,32H,17H2,1-8H3,(H,30,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	75.2	-42.3	n/a	n/a	n/a	n/a	n/a	n/a	37
Gruenenthal GmbH US Patent					Assay Description The agonistic or antagonistic effect of the substances to be tested on the vanilloid receptor 1 (VR1) can also be determined using the following assa...				US Patent US9120756 (2015) BindingDB Entry DOI: 10.7270/Q26D5RRG
					More data for this Ligand-Target Pair

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