BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 7209
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ) (Yersinia pestis)	BDBM24777 (5-hydroxy-1,4-dihydronaphthalene-1,4-dione \| 5-hyd...) Show SMILES Oc1cccc2C(=O)C=CC(=O)c12 \|c:8\| Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair
beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ) (Francisella tularensis)	BDBM24777 (5-hydroxy-1,4-dihydronaphthalene-1,4-dione \| 5-hyd...) Show SMILES Oc1cccc2C(=O)C=CC(=O)c12 \|c:8\| Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair
beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ) (Yersinia pestis)	BDBM50214969 (1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair
beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ) (Francisella tularensis)	BDBM50214969 (1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair
beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ) (Yersinia pestis)	BDBM50056922 (1,4-Dihydroxy-10-methoxy-5,8-dimethyl-3,7-dioxo-1,...) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair
beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ) (Francisella tularensis)	BDBM50056922 (1,4-Dihydroxy-10-methoxy-5,8-dimethyl-3,7-dioxo-1,...) Show SMILES Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair
beta-Hydroxyacyl-acyl carrier protein dehydratase (YpFabZ) (Yersinia pestis)	BDBM11318 (1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...) Show SMILES Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	2.97E+4	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair
beta-Hydroxyacyl-acyl carrier protein dehydratase (FtFabZ) (Francisella tularensis)	BDBM11318 (1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...) Show SMILES Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1 Show InChI	PDB GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	4.31E+4	n/a	n/a	n/a	n/a	7.0	25
Brookhaven National Laboratory					Assay Description The enzymatic activities of FtFabZ and YpFabZ were determined via the reportedspectrophotometric method using the substrate analogue crotonoyl-CoA.7 ...				Biochemistry 55: 1091-9 (2016) Article DOI: 10.1021/acs.biochem.5b00832 BindingDB Entry DOI: 10.7270/Q2CN72P1
Brookhaven National Laboratory					More data for this Ligand-Target Pair