Compile Data Set for Download or QSAR

Found 72 hits Enz. Inhib. hit(s) with all data for entry = 7338   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190273 (US9180116, 21C) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C21H27F2NO4/c1-2-3-4-5-18(25)11-10-17-14-21(22,23)20(28)24(17)13-12-15-6-8-16(9-7-15)19(26)27/h6-11,17-18,25H,2-5,12-14H2,1H3,(H,26,27)/b11-10+/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0820	n/a	0.220	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190282 (US9180116, 33C) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C20H27F2NO4S/c1-2-3-4-6-15(24)9-8-14-13-20(21,22)19(27)23(14)12-5-7-16-10-11-17(28-16)18(25)26/h8-11,14-15,24H,2-7,12-13H2,1H3,(H,25,26)/b9-8+/t14-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	0.280	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190272 (US9180116, 12D) Show SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H27F2NO4/c1-3-4-5-6-16(2)20(27)12-11-19-15-23(24,25)22(30)26(19)14-13-17-7-9-18(10-8-17)21(28)29/h7-12,16,19-20,27H,3,6,13-15H2,1-2H3,(H,28,29)/b12-11+/t16-,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.120	n/a	0.320	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50101822 ((Z)-7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-o...) Show SMILES CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	0.140	n/a	0.380	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190270 (US9180116, 9C) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H31F2NO4/c1-2-3-6-9-16(23)12-11-15-14-19(20,21)18(26)22(15)13-8-5-4-7-10-17(24)25/h11-12,15-16,23H,2-10,13-14H2,1H3,(H,24,25)/b12-11+/t15-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.210	n/a	0.570	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190275 (US9180116, 28C | US9180116, 28H) Show SMILES C[C@@H](CCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C26H31F2NO4S/c1-18(7-5-10-19-8-3-2-4-9-19)22(30)14-12-20-17-26(27,28)25(33)29(20)16-6-11-21-13-15-23(34-21)24(31)32/h2-4,8-9,12-15,18,20,22,30H,5-7,10-11,16-17H2,1H3,(H,31,32)/b14-12+/t18-,20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.280	n/a	0.740	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190267 (US9180116, 1F) Show SMILES CC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C20H29F2NO4/c1-3-4-9-15(2)17(24)12-11-16-14-20(21,22)19(27)23(16)13-8-6-5-7-10-18(25)26/h11-12,15-17,24H,5-10,13-14H2,1-2H3,(H,25,26)/b12-11+/t15-,16-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.440	n/a	1.20	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190268 (US9180116, 2C) Show SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C21H31F2NO4/c1-3-4-7-10-16(2)18(25)13-12-17-15-21(22,23)20(28)24(17)14-9-6-5-8-11-19(26)27/h12-13,16-18,25H,3,5-6,8-11,14-15H2,1-2H3,(H,26,27)/b13-12+/t16-,17-,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.490	n/a	1.30	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190269 (US9180116, 6D) Show SMILES C[C@@H](CCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C25H35F2NO4/c1-19(10-9-13-20-11-5-4-6-12-20)22(29)16-15-21-18-25(26,27)24(32)28(21)17-8-3-2-7-14-23(30)31/h4-6,11-12,15-16,19,21-22,29H,2-3,7-10,13-14,17-18H2,1H3,(H,30,31)/b16-15+/t19-,21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.890	n/a	2.40	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190274 (US9180116, 24D) Show SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C22H27F2NO4S/c1-3-4-5-7-15(2)18(26)11-9-16-14-22(23,24)21(29)25(16)13-6-8-17-10-12-19(30-17)20(27)28/h9-12,15-16,18,26H,3,6-8,13-14H2,1-2H3,(H,27,28)/b11-9+/t15-,16-,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	n/a	3.30	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190271 (US9180116, 10C) Show SMILES O[C@@H](CCCCc1ccccc1)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C24H33F2NO4/c25-24(26)18-20(27(23(24)31)17-9-2-1-6-14-22(29)30)15-16-21(28)13-8-7-12-19-10-4-3-5-11-19/h3-5,10-11,15-16,20-21,28H,1-2,6-9,12-14,17-18H2,(H,29,30)/b16-15+/t20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.80	n/a	4.90	n/a	n/a	n/a	n/a	6.0	n/a
Cayman Chemical Company, Inc. US Patent					Assay Description Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50101822 ((Z)-7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-o...) Show SMILES CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.480	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50101828 (7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-oct-1...) Show SMILES CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O Show InChI InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16-,17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.220	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190267 (US9180116, 1F) Show SMILES CC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C20H29F2NO4/c1-3-4-9-15(2)17(24)12-11-16-14-20(21,22)19(27)23(16)13-8-6-5-7-10-18(25)26/h11-12,15-17,24H,5-10,13-14H2,1-2H3,(H,25,26)/b12-11+/t15-,16-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190268 (US9180116, 2C) Show SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C21H31F2NO4/c1-3-4-7-10-16(2)18(25)13-12-17-15-21(22,23)20(28)24(17)14-9-6-5-8-11-19(26)27/h12-13,16-18,25H,3,5-6,8-11,14-15H2,1-2H3,(H,26,27)/b13-12+/t16-,17-,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.240	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190269 (US9180116, 6D) Show SMILES C[C@@H](CCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C25H35F2NO4/c1-19(10-9-13-20-11-5-4-6-12-20)22(29)16-15-21-18-25(26,27)24(32)28(21)17-8-3-2-7-14-23(30)31/h4-6,11-12,15-16,19,21-22,29H,2-3,7-10,13-14,17-18H2,1H3,(H,30,31)/b16-15+/t19-,21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0230	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190270 (US9180116, 9C) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H31F2NO4/c1-2-3-6-9-16(23)12-11-15-14-19(20,21)18(26)22(15)13-8-5-4-7-10-17(24)25/h11-12,15-16,23H,2-10,13-14H2,1H3,(H,24,25)/b12-11+/t15-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.370	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190271 (US9180116, 10C) Show SMILES O[C@@H](CCCCc1ccccc1)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C24H33F2NO4/c25-24(26)18-20(27(23(24)31)17-9-2-1-6-14-22(29)30)15-16-21(28)13-8-7-12-19-10-4-3-5-11-19/h3-5,10-11,15-16,20-21,28H,1-2,6-9,12-14,17-18H2,(H,29,30)/b16-15+/t20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190272 (US9180116, 12D) Show SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H27F2NO4/c1-3-4-5-6-16(2)20(27)12-11-19-15-23(24,25)22(30)26(19)14-13-17-7-9-18(10-8-17)21(28)29/h7-12,16,19-20,27H,3,6,13-15H2,1-2H3,(H,28,29)/b12-11+/t16-,19-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0470	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190273 (US9180116, 21C) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCc1ccc(cc1)C(O)=O Show InChI InChI=1S/C21H27F2NO4/c1-2-3-4-5-18(25)11-10-17-14-21(22,23)20(28)24(17)13-12-15-6-8-16(9-7-15)19(26)27/h6-11,17-18,25H,2-5,12-14H2,1H3,(H,26,27)/b11-10+/t17-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.610	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190274 (US9180116, 24D) Show SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C22H27F2NO4S/c1-3-4-5-7-15(2)18(26)11-9-16-14-22(23,24)21(29)25(16)13-6-8-17-10-12-19(30-17)20(27)28/h9-12,15-16,18,26H,3,6-8,13-14H2,1-2H3,(H,27,28)/b11-9+/t15-,16-,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.730	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190275 (US9180116, 28C | US9180116, 28H) Show SMILES C[C@@H](CCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C26H31F2NO4S/c1-18(7-5-10-19-8-3-2-4-9-19)22(30)14-12-20-17-26(27,28)25(33)29(20)16-6-11-21-13-15-23(34-21)24(31)32/h2-4,8-9,12-15,18,20,22,30H,5-7,10-11,16-17H2,1H3,(H,31,32)/b14-12+/t18-,20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0100	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190276 (US9180116, 28D | US9180116, 28G) Show SMILES C[C@@H](CCCc1ccccc1)[C@@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C26H31F2NO4S/c1-18(7-5-10-19-8-3-2-4-9-19)22(30)14-12-20-17-26(27,28)25(33)29(20)16-6-11-21-13-15-23(34-21)24(31)32/h2-4,8-9,12-15,18,20,22,30H,5-7,10-11,16-17H2,1H3,(H,31,32)/b14-12+/t18-,20-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	5.68	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190277 (US9180116, 28E) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@H](O)[C@@H](C)CCCc2ccccc2)s1 Show InChI InChI=1S/C27H33F2NO4S/c1-19(8-6-11-20-9-4-3-5-10-20)23(31)15-13-21-18-27(28,29)26(33)30(21)17-7-12-22-14-16-24(35-22)25(32)34-2/h3-5,9-10,13-16,19,21,23,31H,6-8,11-12,17-18H2,1-2H3/b15-13+/t19-,21-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	50.8	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190278 (US9180116, 28F) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@@H](O)[C@@H](C)CCCc2ccccc2)s1 Show InChI InChI=1S/C27H33F2NO4S/c1-19(8-6-11-20-9-4-3-5-10-20)23(31)15-13-21-18-27(28,29)26(33)30(21)17-7-12-22-14-16-24(35-22)25(32)34-2/h3-5,9-10,13-16,19,21,23,31H,6-8,11-12,17-18H2,1-2H3/b15-13+/t19-,21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190276 (US9180116, 28D | US9180116, 28G) Show SMILES C[C@@H](CCCc1ccccc1)[C@@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C26H31F2NO4S/c1-18(7-5-10-19-8-3-2-4-9-19)22(30)14-12-20-17-26(27,28)25(33)29(20)16-6-11-21-13-15-23(34-21)24(31)32/h2-4,8-9,12-15,18,20,22,30H,5-7,10-11,16-17H2,1H3,(H,31,32)/b14-12+/t18-,20-,22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0162	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190275 (US9180116, 28C | US9180116, 28H) Show SMILES C[C@@H](CCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C26H31F2NO4S/c1-18(7-5-10-19-8-3-2-4-9-19)22(30)14-12-20-17-26(27,28)25(33)29(20)16-6-11-21-13-15-23(34-21)24(31)32/h2-4,8-9,12-15,18,20,22,30H,5-7,10-11,16-17H2,1H3,(H,31,32)/b14-12+/t18-,20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	3.15	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190281 (US9180116, 28C-H2) Show SMILES C[C@@H](CCCc1ccccc1)[C@H](O)CC[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C26H33F2NO4S/c1-18(7-5-10-19-8-3-2-4-9-19)22(30)14-12-20-17-26(27,28)25(33)29(20)16-6-11-21-13-15-23(34-21)24(31)32/h2-4,8-9,13,15,18,20,22,30H,5-7,10-12,14,16-17H2,1H3,(H,31,32)/t18-,20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.00290	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190282 (US9180116, 33C) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C20H27F2NO4S/c1-2-3-4-6-15(24)9-8-14-13-20(21,22)19(27)23(14)12-5-7-16-10-11-17(28-16)18(25)26/h8-11,14-15,24H,2-7,12-13H2,1H3,(H,25,26)/b9-8+/t14-,15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0790	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190283 (US9180116, 35C) Show SMILES C[C@H]([C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O)c1ccccc1 Show InChI InChI=1S/C23H25F2NO4S/c1-15(16-6-3-2-4-7-16)19(27)11-9-17-14-23(24,25)22(30)26(17)13-5-8-18-10-12-20(31-18)21(28)29/h2-4,6-7,9-12,15,17,19,27H,5,8,13-14H2,1H3,(H,28,29)/b11-9+/t15-,17-,19+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	62	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190284 (US9180116, 36A) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@@H](O)[C@@H](C)Cc2ccccc2)s1 Show InChI InChI=1S/C25H29F2NO4S/c1-17(15-18-7-4-3-5-8-18)21(29)12-10-19-16-25(26,27)24(31)28(19)14-6-9-20-11-13-22(33-20)23(30)32-2/h3-5,7-8,10-13,17,19,21,29H,6,9,14-16H2,1-2H3/b12-10+/t17-,19-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	5.02	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190285 (US9180116, 36B) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@H](O)[C@@H](C)Cc2ccccc2)s1 Show InChI InChI=1S/C25H29F2NO4S/c1-17(15-18-7-4-3-5-8-18)21(29)12-10-19-16-25(26,27)24(31)28(19)14-6-9-20-11-13-22(33-20)23(30)32-2/h3-5,7-8,10-13,17,19,21,29H,6,9,14-16H2,1-2H3/b12-10+/t17-,19-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190286 (US9180116, 36C) Show SMILES C[C@@H](Cc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C24H27F2NO4S/c1-16(14-17-6-3-2-4-7-17)20(28)11-9-18-15-24(25,26)23(31)27(18)13-5-8-19-10-12-21(32-19)22(29)30/h2-4,6-7,9-12,16,18,20,28H,5,8,13-15H2,1H3,(H,29,30)/b11-9+/t16-,18-,20+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0380	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190287 (US9180116, 37A) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@@H](O)[C@@H](C)CCc2ccccc2)s1 Show InChI InChI=1S/C26H31F2NO4S/c1-18(10-11-19-7-4-3-5-8-19)22(30)14-12-20-17-26(27,28)25(32)29(20)16-6-9-21-13-15-23(34-21)24(31)33-2/h3-5,7-8,12-15,18,20,22,30H,6,9-11,16-17H2,1-2H3/b14-12+/t18-,20-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	8.09	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190288 (US9180116, 37C) Show SMILES C[C@@H](CCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C25H29F2NO4S/c1-17(9-10-18-6-3-2-4-7-18)21(29)13-11-19-16-25(26,27)24(32)28(19)15-5-8-20-12-14-22(33-20)23(30)31/h2-4,6-7,11-14,17,19,21,29H,5,8-10,15-16H2,1H3,(H,30,31)/b13-11+/t17-,19-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190289 (US9180116, 37D) Show SMILES C[C@@H](CCc1ccccc1)[C@@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C25H29F2NO4S/c1-17(9-10-18-6-3-2-4-7-18)21(29)13-11-19-16-25(26,27)24(32)28(19)15-5-8-20-12-14-22(33-20)23(30)31/h2-4,6-7,11-14,17,19,21,29H,5,8-10,15-16H2,1H3,(H,30,31)/b13-11+/t17-,19-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	198	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190290 (US9180116, 38A) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@@H](O)[C@@H](C)CCCCc2ccccc2)s1 Show InChI InChI=1S/C28H35F2NO4S/c1-20(9-6-7-12-21-10-4-3-5-11-21)24(32)16-14-22-19-28(29,30)27(34)31(22)18-8-13-23-15-17-25(36-23)26(33)35-2/h3-5,10-11,14-17,20,22,24,32H,6-9,12-13,18-19H2,1-2H3/b16-14+/t20-,22-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190291 (US9180116, 38B) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@H](O)[C@@H](C)CCCCc2ccccc2)s1 Show InChI InChI=1S/C28H35F2NO4S/c1-20(9-6-7-12-21-10-4-3-5-11-21)24(32)16-14-22-19-28(29,30)27(34)31(22)18-8-13-23-15-17-25(36-23)26(33)35-2/h3-5,10-11,14-17,20,22,24,32H,6-9,12-13,18-19H2,1-2H3/b16-14+/t20-,22-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190292 (US9180116, 38C) Show SMILES C[C@@H](CCCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C27H33F2NO4S/c1-19(8-5-6-11-20-9-3-2-4-10-20)23(31)15-13-21-18-27(28,29)26(34)30(21)17-7-12-22-14-16-24(35-22)25(32)33/h2-4,9-10,13-16,19,21,23,31H,5-8,11-12,17-18H2,1H3,(H,32,33)/b15-13+/t19-,21-,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	1.40E-7	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190293 (US9180116, 38D) Show SMILES C[C@@H](CCCCc1ccccc1)[C@@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C27H33F2NO4S/c1-19(8-5-6-11-20-9-3-2-4-10-20)23(31)15-13-21-18-27(28,29)26(34)30(21)17-7-12-22-14-16-24(35-22)25(32)33/h2-4,9-10,13-16,19,21,23,31H,5-8,11-12,17-18H2,1H3,(H,32,33)/b15-13+/t19-,21-,23-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.370	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190294 (US9180116, 39A) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@@H](O)[C@@H](C)CCCCCc2ccccc2)s1 Show InChI InChI=1S/C29H37F2NO4S/c1-21(10-5-3-6-11-22-12-7-4-8-13-22)25(33)17-15-23-20-29(30,31)28(35)32(23)19-9-14-24-16-18-26(37-24)27(34)36-2/h4,7-8,12-13,15-18,21,23,25,33H,3,5-6,9-11,14,19-20H2,1-2H3/b17-15+/t21-,23-,25+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190295 (US9180116, 39B) Show SMILES COC(=O)c1ccc(CCCN2[C@H](CC(F)(F)C2=O)\C=C\[C@H](O)[C@@H](C)CCCCCc2ccccc2)s1 Show InChI InChI=1S/C29H37F2NO4S/c1-21(10-5-3-6-11-22-12-7-4-8-13-22)25(33)17-15-23-20-29(30,31)28(35)32(23)19-9-14-24-16-18-26(37-24)27(34)36-2/h4,7-8,12-13,15-18,21,23,25,33H,3,5-6,9-11,14,19-20H2,1-2H3/b17-15+/t21-,23-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	>1.00E+3	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190296 (US9180116, 39C) Show SMILES C[C@@H](CCCCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C28H35F2NO4S/c1-20(9-4-2-5-10-21-11-6-3-7-12-21)24(32)16-14-22-19-28(29,30)27(35)31(22)18-8-13-23-15-17-25(36-23)26(33)34/h3,6-7,11-12,14-17,20,22,24,32H,2,4-5,8-10,13,18-19H2,1H3,(H,33,34)/b16-14+/t20-,22-,24+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.00000270	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190297 (US9180116, 39D) Show SMILES C[C@@H](CCCCCc1ccccc1)[C@@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O Show InChI InChI=1S/C28H35F2NO4S/c1-20(9-4-2-5-10-21-11-6-3-7-12-21)24(32)16-14-22-19-28(29,30)27(35)31(22)18-8-13-23-15-17-25(36-23)26(33)34/h3,6-7,11-12,14-17,20,22,24,32H,2,4-5,8-10,13,18-19H2,1H3,(H,33,34)/b16-14+/t20-,22-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0590	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50101822 ((Z)-7-[(1R,2R,3R)-3-Hydroxy-2-((E)-(R)-3-hydroxy-o...) Show SMILES CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O Show InChI InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16-,17-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0500	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190267 (US9180116, 1F) Show SMILES CC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C20H29F2NO4/c1-3-4-9-15(2)17(24)12-11-16-14-20(21,22)19(27)23(16)13-8-6-5-7-10-18(25)26/h11-12,15-17,24H,5-10,13-14H2,1-2H3,(H,25,26)/b12-11+/t15-,16-,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0590	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190268 (US9180116, 2C) Show SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C21H31F2NO4/c1-3-4-7-10-16(2)18(25)13-12-17-15-21(22,23)20(28)24(17)14-9-6-5-8-11-19(26)27/h12-13,16-18,25H,3,5-6,8-11,14-15H2,1-2H3,(H,26,27)/b13-12+/t16-,17-,18+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0380	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190269 (US9180116, 6D) Show SMILES C[C@@H](CCCc1ccccc1)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C25H35F2NO4/c1-19(10-9-13-20-11-5-4-6-12-20)22(29)16-15-21-18-25(26,27)24(32)28(21)17-8-3-2-7-14-23(30)31/h4-6,11-12,15-16,19,21-22,29H,2-3,7-10,13-14,17-18H2,1H3,(H,30,31)/b16-15+/t19-,21-,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	<0.00100	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190270 (US9180116, 9C) Show SMILES CCCCC[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C19H31F2NO4/c1-2-3-6-9-16(23)12-11-15-14-19(20,21)18(26)22(15)13-8-5-4-7-10-17(24)25/h11-12,15-16,23H,2-10,13-14H2,1H3,(H,24,25)/b12-11+/t15-,16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0590	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM190271 (US9180116, 10C) Show SMILES O[C@@H](CCCCc1ccccc1)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O Show InChI InChI=1S/C24H33F2NO4/c25-24(26)18-20(27(23(24)31)17-9-2-1-6-14-22(29)30)15-16-21(28)13-8-7-12-19-10-4-3-5-11-19/h3-5,10-11,15-16,20-21,28H,1-2,6-9,12-14,17-18H2,(H,29,30)/b16-15+/t20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.0100	n/a	n/a	n/a	37
Cayman Chemical Company, Inc. US Patent					Assay Description 1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...				US Patent US9180116 (2015) BindingDB Entry DOI: 10.7270/Q2QC029S
					More data for this Ligand-Target Pair

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