Compile Data Set for Download or QSAR

Found 57 hits Enz. Inhib. hit(s) with all data for entry = 2303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19136 (CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCCCC1 |r| Show InChI InChI=1S/C19H36N2O3S/c1-19(2,3)24-18(23)21-16(13-9-6-10-14-25)17(22)20-15-11-7-4-5-8-12-15/h15-16,25H,4-14H2,1-3H3,(H,20,22)(H,21,23)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19134 (CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H32N2O3S/c1-17(2,3)22-16(21)19-14(11-5-4-8-12-23)15(20)18-13-9-6-7-10-13/h13-14,23H,4-12H2,1-3H3,(H,18,20)(H,19,21)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19133 (tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)Nc1cnc2ccccc2c1 |r| Show InChI InChI=1S/C21H29N3O3S/c1-21(2,3)27-20(26)24-18(11-5-4-8-12-28)19(25)23-16-13-15-9-6-7-10-17(15)22-14-16/h6-7,9-10,13-14,18,28H,4-5,8,11-12H2,1-3H3,(H,23,25)(H,24,26)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19131 (CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...) Show SMILES SCCCCCCC(=O)Nc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C16H20N2OS2/c19-15(10-6-1-2-7-11-20)18-16-17-14(12-21-16)13-8-4-3-5-9-13/h3-5,8-9,12,20H,1-2,6-7,10-11H2,(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19133 (tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)Nc1cnc2ccccc2c1 |r| Show InChI InChI=1S/C21H29N3O3S/c1-21(2,3)27-20(26)24-18(11-5-4-8-12-28)19(25)23-16-13-15-9-6-7-10-17(15)22-14-16/h6-7,9-10,13-14,18,28H,4-5,8,11-12H2,1-3H3,(H,23,25)(H,24,26)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19135 (CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCCC1 |r| Show InChI InChI=1S/C18H34N2O3S/c1-18(2,3)23-17(22)20-15(12-8-5-9-13-24)16(21)19-14-10-6-4-7-11-14/h14-15,24H,4-13H2,1-3H3,(H,19,21)(H,20,22)/t15-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19132 (tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)Nc1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C24H32N2O3S/c1-24(2,3)29-23(28)26-21(15-8-5-9-16-30)22(27)25-20-14-10-13-19(17-20)18-11-6-4-7-12-18/h4,6-7,10-14,17,21,30H,5,8-9,15-16H2,1-3H3,(H,25,27)(H,26,28)/t21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19131 (CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...) Show SMILES SCCCCCCC(=O)Nc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C16H20N2OS2/c19-15(10-6-1-2-7-11-20)18-16-17-14(12-21-16)13-8-4-3-5-9-13/h3-5,8-9,12,20H,1-2,6-7,10-11H2,(H,17,18,19)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19131 (CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...) Show SMILES SCCCCCCC(=O)Nc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C16H20N2OS2/c19-15(10-6-1-2-7-11-20)18-16-17-14(12-21-16)13-8-4-3-5-9-13/h3-5,8-9,12,20H,1-2,6-7,10-11H2,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19133 (tert-butyl N-[(1S)-1-(quinolin-3-ylcarbamoyl)-6-su...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)Nc1cnc2ccccc2c1 |r| Show InChI InChI=1S/C21H29N3O3S/c1-21(2,3)27-20(26)24-18(11-5-4-8-12-28)19(25)23-16-13-15-9-6-7-10-17(15)22-14-16/h6-7,9-10,13-14,18,28H,4-5,8,11-12H2,1-3H3,(H,23,25)(H,24,26)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19132 (tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)Nc1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C24H32N2O3S/c1-24(2,3)29-23(28)26-21(15-8-5-9-16-30)22(27)25-20-14-10-13-19(17-20)18-11-6-4-7-12-18/h4,6-7,10-14,17,21,30H,5,8-9,15-16H2,1-3H3,(H,25,27)(H,26,28)/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19132 (tert-butyl N-[(1S)-1-[(3-phenylphenyl)carbamoyl]-6...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)Nc1cccc(c1)-c1ccccc1 |r| Show InChI InChI=1S/C24H32N2O3S/c1-24(2,3)29-23(28)26-21(15-8-5-9-16-30)22(27)25-20-14-10-13-19(17-20)18-11-6-4-7-12-18/h4,6-7,10-14,17,21,30H,5,8-9,15-16H2,1-3H3,(H,25,27)(H,26,28)/t21-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19137 (tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...) Show SMILES CC(C)(C)NC(=O)[C@H](CCCCCS)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C16H32N2O3S/c1-15(2,3)18-13(19)12(10-8-7-9-11-22)17-14(20)21-16(4,5)6/h12,22H,7-11H2,1-6H3,(H,17,20)(H,18,19)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	71	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19148 (benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...) Show SMILES SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C20H30N2O3S/c23-19(21-17-11-6-7-12-17)18(13-5-2-8-14-26)22-20(24)25-15-16-9-3-1-4-10-16/h1,3-4,9-10,17-18,26H,2,5-8,11-15H2,(H,21,23)(H,22,24)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 6 (Mus musculus)	BDBM19138 (tert-butyl N-[(1S)-1-(adamantan-1-ylcarbamoyl)-6-s...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC12CC3CC(CC(C3)C1)C2 |r,TLB:21:22:26:20.19.25,25:20:27:24.26.23,25:24:27:20.19.21,THB:21:20:26:22.27.23| Show InChI InChI=1S/C22H38N2O3S/c1-21(2,3)27-20(26)23-18(7-5-4-6-8-28)19(25)24-22-12-15-9-16(13-22)11-17(10-15)14-22/h15-18,28H,4-14H2,1-3H3,(H,23,26)(H,24,25)/t15?,16?,17?,18-,22?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19144 ((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...) Show SMILES CC(C)(C)NC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H33N3O2S/c1-17(2,3)20-16(22)19-14(11-5-4-8-12-23)15(21)18-13-9-6-7-10-13/h13-14,23H,4-12H2,1-3H3,(H,18,21)(H2,19,20,22)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19146 (methyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...) Show SMILES COC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C14H26N2O3S/c1-19-14(18)16-12(9-3-2-6-10-20)13(17)15-11-7-4-5-8-11/h11-12,20H,2-10H2,1H3,(H,15,17)(H,16,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19147 (cyclohexyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulf...) Show SMILES SCCCCC[C@H](NC(=O)OC1CCCCC1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H34N2O3S/c22-18(20-15-9-6-7-10-15)17(13-5-2-8-14-25)21-19(23)24-16-11-3-1-4-12-16/h15-17,25H,1-14H2,(H,20,22)(H,21,23)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19148 (benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...) Show SMILES SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C20H30N2O3S/c23-19(21-17-11-6-7-12-17)18(13-5-2-8-14-26)22-20(24)25-15-16-9-3-1-4-10-16/h1,3-4,9-10,17-18,26H,2,5-8,11-15H2,(H,21,23)(H,22,24)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19148 (benzyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...) Show SMILES SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C20H30N2O3S/c23-19(21-17-11-6-7-12-17)18(13-5-2-8-14-26)22-20(24)25-15-16-9-3-1-4-10-16/h1,3-4,9-10,17-18,26H,2,5-8,11-15H2,(H,21,23)(H,22,24)/t18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19142 ((2S)-N-cyclopentyl-2-(2-hydroxyacetamido)-7-sulfan...) Show SMILES OCC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C14H26N2O3S/c17-10-13(18)16-12(8-2-1-5-9-20)14(19)15-11-6-3-4-7-11/h11-12,17,20H,1-10H2,(H,15,19)(H,16,18)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19145 ((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...) Show SMILES CC(C)(C)NC(=S)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H33N3OS2/c1-17(2,3)20-16(23)19-14(11-5-4-8-12-22)15(21)18-13-9-6-7-10-13/h13-14,22H,4-12H2,1-3H3,(H,18,21)(H2,19,20,23)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19140 ((2S)-N-cyclopentyl-2-(phenylformamido)-7-sulfanylh...) Show SMILES SCCCCC[C@H](NC(=O)c1ccccc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H28N2O2S/c22-18(15-9-3-1-4-10-15)21-17(13-5-2-8-14-24)19(23)20-16-11-6-7-12-16/h1,3-4,9-10,16-17,24H,2,5-8,11-14H2,(H,20,23)(H,21,22)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19145 ((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...) Show SMILES CC(C)(C)NC(=S)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H33N3OS2/c1-17(2,3)20-16(23)19-14(11-5-4-8-12-22)15(21)18-13-9-6-7-10-13/h13-14,22H,4-12H2,1-3H3,(H,18,21)(H2,19,20,23)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19140 ((2S)-N-cyclopentyl-2-(phenylformamido)-7-sulfanylh...) Show SMILES SCCCCC[C@H](NC(=O)c1ccccc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H28N2O2S/c22-18(15-9-3-1-4-10-15)21-17(13-5-2-8-14-24)19(23)20-16-11-6-7-12-16/h1,3-4,9-10,16-17,24H,2,5-8,11-14H2,(H,20,23)(H,21,22)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19144 ((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...) Show SMILES CC(C)(C)NC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H33N3O2S/c1-17(2,3)20-16(22)19-14(11-5-4-8-12-23)15(21)18-13-9-6-7-10-13/h13-14,23H,4-12H2,1-3H3,(H,18,21)(H2,19,20,22)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19145 ((2S)-2-[(tert-butylcarbamothioyl)amino]-N-cyclopen...) Show SMILES CC(C)(C)NC(=S)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H33N3OS2/c1-17(2,3)20-16(23)19-14(11-5-4-8-12-22)15(21)18-13-9-6-7-10-13/h13-14,22H,4-12H2,1-3H3,(H,18,21)(H2,19,20,23)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19143 ((2S)-N-cyclopentyl-2-(2,2-dimethylpropanamido)-7-s...) Show SMILES CC(C)(C)C(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H32N2O2S/c1-17(2,3)16(21)19-14(11-5-4-8-12-22)15(20)18-13-9-6-7-10-13/h13-14,22H,4-12H2,1-3H3,(H,18,20)(H,19,21)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19144 ((2S)-2-[(tert-butylcarbamoyl)amino]-N-cyclopentyl-...) Show SMILES CC(C)(C)NC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H33N3O2S/c1-17(2,3)20-16(22)19-14(11-5-4-8-12-23)15(21)18-13-9-6-7-10-13/h13-14,23H,4-12H2,1-3H3,(H,18,21)(H2,19,20,22)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Mus musculus)	BDBM19141 ((2S)-2-[(4-chlorophenyl)formamido]-N-cyclopentyl-7...) Show SMILES SCCCCC[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H27ClN2O2S/c20-15-11-9-14(10-12-15)18(23)22-17(8-2-1-5-13-25)19(24)21-16-6-3-4-7-16/h9-12,16-17,25H,1-8,13H2,(H,21,24)(H,22,23)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19140 ((2S)-N-cyclopentyl-2-(phenylformamido)-7-sulfanylh...) Show SMILES SCCCCC[C@H](NC(=O)c1ccccc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H28N2O2S/c22-18(15-9-3-1-4-10-15)21-17(13-5-2-8-14-24)19(23)20-16-11-6-7-12-16/h1,3-4,9-10,16-17,24H,2,5-8,11-14H2,(H,20,23)(H,21,22)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19147 (cyclohexyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulf...) Show SMILES SCCCCC[C@H](NC(=O)OC1CCCCC1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H34N2O3S/c22-18(20-15-9-6-7-10-15)17(13-5-2-8-14-25)21-19(23)24-16-11-3-1-4-12-16/h15-17,25H,1-14H2,(H,20,22)(H,21,23)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19141 ((2S)-2-[(4-chlorophenyl)formamido]-N-cyclopentyl-7...) Show SMILES SCCCCC[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H27ClN2O2S/c20-15-11-9-14(10-12-15)18(23)22-17(8-2-1-5-13-25)19(24)21-16-6-3-4-7-16/h9-12,16-17,25H,1-8,13H2,(H,21,24)(H,22,23)/t17-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19143 ((2S)-N-cyclopentyl-2-(2,2-dimethylpropanamido)-7-s...) Show SMILES CC(C)(C)C(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H32N2O2S/c1-17(2,3)16(21)19-14(11-5-4-8-12-22)15(20)18-13-9-6-7-10-13/h13-14,22H,4-12H2,1-3H3,(H,18,20)(H,19,21)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19136 (CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCCCC1 |r| Show InChI InChI=1S/C19H36N2O3S/c1-19(2,3)24-18(23)21-16(13-9-6-10-14-25)17(22)20-15-11-7-4-5-8-12-15/h15-16,25H,4-14H2,1-3H3,(H,20,22)(H,21,23)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19136 (CHEMBL379049 | tert-butyl N-[(1S)-1-(cycloheptylca...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCCCC1 |r| Show InChI InChI=1S/C19H36N2O3S/c1-19(2,3)24-18(23)21-16(13-9-6-10-14-25)17(22)20-15-11-7-4-5-8-12-15/h15-16,25H,4-14H2,1-3H3,(H,20,22)(H,21,23)/t16-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19142 ((2S)-N-cyclopentyl-2-(2-hydroxyacetamido)-7-sulfan...) Show SMILES OCC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C14H26N2O3S/c17-10-13(18)16-12(8-2-1-5-9-20)14(19)15-11-6-3-4-7-11/h11-12,17,20H,1-10H2,(H,15,19)(H,16,18)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19147 (cyclohexyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulf...) Show SMILES SCCCCC[C@H](NC(=O)OC1CCCCC1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H34N2O3S/c22-18(20-15-9-6-7-10-15)17(13-5-2-8-14-25)21-19(23)24-16-11-3-1-4-12-16/h15-17,25H,1-14H2,(H,20,22)(H,21,23)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19134 (CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H32N2O3S/c1-17(2,3)22-16(21)19-14(11-5-4-8-12-23)15(20)18-13-9-6-7-10-13/h13-14,23H,4-12H2,1-3H3,(H,18,20)(H,19,21)/t14-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19135 (CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCCC1 |r| Show InChI InChI=1S/C18H34N2O3S/c1-18(2,3)23-17(22)20-15(12-8-5-9-13-24)16(21)19-14-10-6-4-7-11-14/h14-15,24H,4-13H2,1-3H3,(H,19,21)(H,20,22)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19146 (methyl N-[(1S)-1-(cyclopentylcarbamoyl)-6-sulfanyl...) Show SMILES COC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C14H26N2O3S/c1-19-14(18)16-12(9-3-2-6-10-20)13(17)15-11-7-4-5-8-11/h11-12,20H,2-10H2,1H3,(H,15,17)(H,16,18)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19134 (CHEMBL213934 | tert-butyl N-[(1S)-1-(cyclopentylca...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H32N2O3S/c1-17(2,3)22-16(21)19-14(11-5-4-8-12-23)15(20)18-13-9-6-7-10-13/h13-14,23H,4-12H2,1-3H3,(H,18,20)(H,19,21)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19135 (CHEMBL209551 | tert-butyl N-[(1S)-1-(cyclohexylcar...) Show SMILES CC(C)(C)OC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCCC1 |r| Show InChI InChI=1S/C18H34N2O3S/c1-18(2,3)23-17(22)20-15(12-8-5-9-13-24)16(21)19-14-10-6-4-7-11-14/h14-15,24H,4-13H2,1-3H3,(H,19,21)(H,20,22)/t15-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	8.0	37
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19143 ((2S)-N-cyclopentyl-2-(2,2-dimethylpropanamido)-7-s...) Show SMILES CC(C)(C)C(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C17H32N2O2S/c1-17(2,3)16(21)19-14(11-5-4-8-12-22)15(20)18-13-9-6-7-10-13/h13-14,22H,4-12H2,1-3H3,(H,18,20)(H,19,21)/t14-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19141 ((2S)-2-[(4-chlorophenyl)formamido]-N-cyclopentyl-7...) Show SMILES SCCCCC[C@H](NC(=O)c1ccc(Cl)cc1)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C19H27ClN2O2S/c20-15-11-9-14(10-12-15)18(23)22-17(8-2-1-5-13-25)19(24)21-16-6-3-4-7-16/h9-12,16-17,25H,1-8,13H2,(H,21,24)(H,22,23)/t17-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19137 (tert-butyl N-[(1S)-1-(tert-butylcarbamoyl)-6-sulfa...) Show SMILES CC(C)(C)NC(=O)[C@H](CCCCCS)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C16H32N2O3S/c1-15(2,3)18-13(19)12(10-8-7-9-11-22)17-14(20)21-16(4,5)6/h12,22H,7-11H2,1-6H3,(H,17,20)(H,18,19)/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19142 ((2S)-N-cyclopentyl-2-(2-hydroxyacetamido)-7-sulfan...) Show SMILES OCC(=O)N[C@@H](CCCCCS)C(=O)NC1CCCC1 |r| Show InChI InChI=1S/C14H26N2O3S/c17-10-13(18)16-12(8-2-1-5-9-20)14(19)15-11-6-3-4-7-11/h11-12,17,20H,1-10H2,(H,15,19)(H,16,18)/t12-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nagoya City University					Assay Description The enzyme activity was assayed using recombinant HDAC and [3H] acetyl-labeled histones as substrate. The released [3H]acetic acid was extracted and ...				J Med Chem 50: 5425-38 (2007) Article DOI: 10.1021/jm7009217 BindingDB Entry DOI: 10.7270/Q2XK8CT6
					More data for this Ligand-Target Pair

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