Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM19188 (7-(3-chlorobenzyloxy)-4-(methylamino)methyl-coumar...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 100 | -40.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Pavia | Assay Description MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ... | J Med Chem 50: 5848-5852 (2007) Article DOI: 10.1021/jm070677y BindingDB Entry DOI: 10.7270/Q2DN43B4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM19189 (7-(3-Chlorobenzyloxy)-4-carboxaldehyde-coumarin, 3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 400 | -36.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Pavia | Assay Description MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ... | J Med Chem 50: 5848-5852 (2007) Article DOI: 10.1021/jm070677y BindingDB Entry DOI: 10.7270/Q2DN43B4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amine oxidase [flavin-containing] B (Homo sapiens (Human)) | BDBM19187 ((2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 450 | -36.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Pavia | Assay Description MAO B activities were determined spectrophotometrically at 250 nm using benzylamine as substrate. Competitive Ki values were determined by measuring ... | J Med Chem 50: 5848-5852 (2007) Article DOI: 10.1021/jm070677y BindingDB Entry DOI: 10.7270/Q2DN43B4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM19189 (7-(3-Chlorobenzyloxy)-4-carboxaldehyde-coumarin, 3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.10E+4 | -28.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Pavia | Assay Description MAO A activities were determined spectrophotometrically at 316 nm using kynuramine as substrate. Competitive Ki values were determined by measuring i... | J Med Chem 50: 5848-5852 (2007) Article DOI: 10.1021/jm070677y BindingDB Entry DOI: 10.7270/Q2DN43B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM19188 (7-(3-chlorobenzyloxy)-4-(methylamino)methyl-coumar...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 1.57E+4 | -27.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Pavia | Assay Description MAO A activities were determined spectrophotometrically at 316 nm using kynuramine as substrate. Competitive Ki values were determined by measuring i... | J Med Chem 50: 5848-5852 (2007) Article DOI: 10.1021/jm070677y BindingDB Entry DOI: 10.7270/Q2DN43B4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM19187 ((2S)-2-[({4-[(3-fluorophenyl)methoxy]phenyl}methyl...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 3.65E+5 | -19.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Pavia | Assay Description MAO A activities were determined spectrophotometrically at 316 nm using kynuramine as substrate. Competitive Ki values were determined by measuring i... | J Med Chem 50: 5848-5852 (2007) Article DOI: 10.1021/jm070677y BindingDB Entry DOI: 10.7270/Q2DN43B4 | |||||||||||
More data for this Ligand-Target Pair |