BindingDB PrimarySearch

Found 23 hits Enz. Inhib. hit(s) with all data for entry = 7502
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198173 (2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198172 (2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198171 (2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198174 (2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198176 (2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	880	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198175 (2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	960	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198173 (2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198172 (2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198171 (2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198174 (2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198176 (2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM198175 (2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM17638 (2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198174 (2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198171 (2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198175 (2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198173 (2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198176 (2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM198172 (2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indian Institute of Technology (Banaras Hindu University)					Assay Description The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...				Bioorg Chem 69: 102-120 (2016) Article DOI: 10.1016/j.bioorg.2016.10.003 BindingDB Entry DOI: 10.7270/Q2SB44K0
Indian Institute of Technology (Banaras Hindu University)					More data for this Ligand-Target Pair