Compile Data Set for Download or QSAR

Found 174 hits Enz. Inhib. hit(s) with all data for entry = 7508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198694 (US9221796, 23b) Show SMILES Cc1ccc(CN2CC[C@@H](N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H28N2O2/c1-17-2-4-18(5-3-17)16-25-15-12-22(23(25)27)24-13-10-20(11-14-24)19-6-8-21(26)9-7-19/h2-9,20,22,26H,10-16H2,1H3/t22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	-54.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198665 (US9221796, 2b) Show SMILES Oc1ccc(cc1)C1CCN(CC1)[C@@H]1CCN(Cc2ccc(F)cc2)C1=O |r| Show InChI InChI=1S/C22H25FN2O2/c23-19-5-1-16(2-6-19)15-25-14-11-21(22(25)27)24-12-9-18(10-13-24)17-3-7-20(26)8-4-17/h1-8,18,21,26H,9-15H2/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.40	-54.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198687 (US9221796, 18b) Show SMILES Oc1ccc(cc1)C1CCN(CC1)[C@@H]1CCN(Cc2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C22H25ClN2O2/c23-19-5-1-16(2-6-19)15-25-14-11-21(22(25)27)24-12-9-18(10-13-24)17-3-7-20(26)8-4-17/h1-8,18,21,26H,9-15H2/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	-54.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198685 (US9221796, 17) Show SMILES Oc1ccc(cc1)C1CCN(CC1)C1CCN(Cc2ccc(Cl)cc2)C1=O Show InChI InChI=1S/C22H25ClN2O2/c23-19-5-1-16(2-6-19)15-25-14-11-21(22(25)27)24-12-9-18(10-13-24)17-3-7-20(26)8-4-17/h1-8,18,21,26H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.60	-54.4	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198681 (US9221796, 13b) Show SMILES Oc1ccc(cc1)C1CCN(CC1)[C@@H]1CCN(Cc2ccccc2)C1=O |r| Show InChI InChI=1S/C22H26N2O2/c25-20-8-6-18(7-9-20)19-10-13-23(14-11-19)21-12-15-24(22(21)26)16-17-4-2-1-3-5-17/h1-9,19,21,25H,10-16H2/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.60	-54.4	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198835 (US9221796, 116) Show SMILES Oc1ccc(cc1F)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C22H23ClF2N2O2/c23-16-4-1-14(2-5-16)12-27-10-8-20(22(27)29)26-9-7-17(19(25)13-26)15-3-6-21(28)18(24)11-15/h1-6,11,17,19-20,28H,7-10,12-13H2/t17-,19+,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	-53.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198724 (US9221796, 45, P-4) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@@H]([C@@H](F)C3)c3ccc(O)c(F)c3)C2=O)cc1F |r| Show InChI InChI=1S/C23H25F3N2O2/c1-14-2-3-15(10-18(14)24)12-28-9-7-21(23(28)30)27-8-6-17(20(26)13-27)16-4-5-22(29)19(25)11-16/h2-5,10-11,17,20-21,29H,6-9,12-13H2,1H3/t17-,20+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.5	-53.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198834 (US9221796, 115) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)c(F)c3)C2=O)cc1 |r| Show InChI InChI=1S/C23H26F2N2O2/c1-15-2-4-16(5-3-15)13-27-11-9-21(23(27)29)26-10-8-18(20(25)14-26)17-6-7-22(28)19(24)12-17/h2-7,12,18,20-21,28H,8-11,13-14H2,1H3/t18-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.70	-53.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198837 (US9221796, 117, P-2) Show SMILES Oc1ccc(cc1F)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccc(cc2)C(F)F)C1=O |r| Show InChI InChI=1S/C23H24F4N2O2/c24-18-11-16(5-6-21(18)30)17-7-9-28(13-19(17)25)20-8-10-29(23(20)31)12-14-1-3-15(4-2-14)22(26)27/h1-6,11,17,19-20,22,30H,7-10,12-13H2/t17-,19+,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.90	-52.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198692 (US9221796, 22) Show SMILES Cc1ccc(CN2CCC(N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1 Show InChI InChI=1S/C23H28N2O2/c1-17-2-4-18(5-3-17)16-25-15-12-22(23(25)27)24-13-10-20(11-14-24)19-6-8-21(26)9-7-19/h2-9,20,22,26H,10-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2.90	-52.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198663 (US9221796, 1) Show SMILES Oc1ccc(cc1)C1CCN(CC1)C1CCN(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C22H25FN2O2/c23-19-5-1-16(2-6-19)15-25-14-11-21(22(25)27)24-12-9-18(10-13-24)17-3-7-20(26)8-4-17/h1-8,18,21,26H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3	-52.7	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198722 (US9221796, 45, P-2) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)c(F)c3)C2=O)cc1F |r| Show InChI InChI=1S/C23H25F3N2O2/c1-14-2-3-15(10-18(14)24)12-28-9-7-21(23(28)30)27-8-6-17(20(26)13-27)16-4-5-22(29)19(25)11-16/h2-5,10-11,17,20-21,29H,6-9,12-13H2,1H3/t17-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.10	-52.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198732 (US9221796, 47, P-4) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@@H]([C@@H](F)C3)c3ccc(O)cc3)C2=O)cc1F |r| Show InChI InChI=1S/C23H26F2N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-22(23(27)29)26-10-8-19(21(25)14-26)17-4-6-18(28)7-5-17/h2-7,12,19,21-22,28H,8-11,13-14H2,1H3/t19-,21+,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.40	-52.4	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198832 (US9221796, 114, P-1) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccc(cc2)C(F)F)C1=O |r| Show InChI InChI=1S/C23H25F3N2O2/c24-20-14-27(11-9-19(20)16-5-7-18(29)8-6-16)21-10-12-28(23(21)30)13-15-1-3-17(4-2-15)22(25)26/h1-8,19-22,29H,9-14H2/t19-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.5	-52.3	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198772 (BDBM198773 | US9221796, 64) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@H]1CCN(Cc2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C22H24ClFN2O2/c23-17-5-1-15(2-6-17)13-26-12-10-21(22(26)28)25-11-9-19(20(24)14-25)16-3-7-18(27)8-4-16/h1-8,19-21,27H,9-14H2/t19-,20+,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.60	-52.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198789 (US9221796, 81) Show SMILES Oc1ccc(cc1)[C@H]1CCN(C[C@@H]1F)[C@@H]1CCN(Cc2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C22H24ClFN2O2/c23-17-5-1-15(2-6-17)13-26-12-10-21(22(26)28)25-11-9-19(20(24)14-25)16-3-7-18(27)8-4-16/h1-8,19-21,27H,9-14H2/t19-,20+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.80	-52.1	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198731 (US9221796, 47, P-3) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1F |r| Show InChI InChI=1S/C23H26F2N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-22(23(27)29)26-10-8-19(21(25)14-26)17-4-6-18(28)7-5-17/h2-7,12,19,21-22,28H,8-11,13-14H2,1H3/t19-,21+,22+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.80	-52.1	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198688 (US9221796, 19) Show SMILES Cc1ccc(CN2CCC(N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1F Show InChI InChI=1S/C23H27FN2O2/c1-16-2-3-17(14-21(16)24)15-26-13-10-22(23(26)28)25-11-8-19(9-12-25)18-4-6-20(27)7-5-18/h2-7,14,19,22,27H,8-13,15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	3.90	-52.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198728 (US9221796, 46, P-4) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21+,22+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	-52.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198679 (US9221796, 12) Show SMILES Oc1ccc(cc1)C1CCN(CC1)C1CCN(Cc2ccccc2)C1=O Show InChI InChI=1S/C22H26N2O2/c25-20-8-6-18(7-9-20)19-10-13-23(14-11-19)21-12-15-24(22(21)26)16-17-4-2-1-3-5-17/h1-9,19,21,25H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	-52.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198726 (US9221796, 46, P-2) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC[C@@H]([C@@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21+,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.30	-51.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198829 (BDBM198830 | US9221796, 112, P-1) Show SMILES Cc1ccc(CN2CCC(N3CC[C@@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21-,22?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.40	-51.7	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198668 (US9221796, 5) Show SMILES Oc1ccc(cc1)C1CCN(CC1)C1CCN(Cc2ccc(F)c(F)c2)C1=O Show InChI InChI=1S/C22H24F2N2O2/c23-19-6-1-15(13-20(19)24)14-26-12-9-21(22(26)28)25-10-7-17(8-11-25)16-2-4-18(27)5-3-16/h1-6,13,17,21,27H,7-12,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.40	-51.7	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198805 (BDBM198821 | US9221796, 95, P-2) Show SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)[C@@H]1CCN(Cc2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C22H23ClF2N2O2/c23-17-5-1-15(2-6-17)13-26-12-10-20(21(26)29)27-11-9-19(22(24,25)14-27)16-3-7-18(28)8-4-16/h1-8,19-20,28H,9-14H2/t19?,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.60	-51.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198695 (US9221796, 24) Show SMILES Oc1ccc(CN2CCC(N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1 Show InChI InChI=1S/C22H26N2O3/c25-19-5-1-16(2-6-19)15-24-14-11-21(22(24)27)23-12-9-18(10-13-23)17-3-7-20(26)8-4-17/h1-8,18,21,25-26H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.70	-51.5	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198703 (US9221796, 30) Show SMILES Oc1ccc(cc1F)C1CCN(CC1)C1CCN(Cc2ccccc2)C1=O Show InChI InChI=1S/C22H25FN2O2/c23-19-14-18(6-7-21(19)26)17-8-11-24(12-9-17)20-10-13-25(22(20)27)15-16-4-2-1-3-5-16/h1-7,14,17,20,26H,8-13,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.70	-51.5	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198670 (US9221796, 6b) Show SMILES Oc1ccc(cc1)C1CCN(CC1)[C@@H]1CCN(Cc2ccc(F)c(F)c2)C1=O |r| Show InChI InChI=1S/C22H24F2N2O2/c23-19-6-1-15(13-20(19)24)14-26-12-9-21(22(26)28)25-10-7-17(8-11-25)16-2-4-18(27)5-3-16/h1-6,13,17,21,27H,7-12,14H2/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.70	-51.5	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198791 (US9221796, 83) Show SMILES Oc1ccc(cc1)[C@H]1CCN(C[C@@H]1F)[C@@H]1CCN(Cc2ccc(Cl)c(F)c2)C1=O |r| Show InChI InChI=1S/C22H23ClF2N2O2/c23-18-6-1-14(11-19(18)24)12-27-10-8-21(22(27)29)26-9-7-17(20(25)13-26)15-2-4-16(28)5-3-15/h1-6,11,17,20-21,28H,7-10,12-13H2/t17-,20+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	-51.4	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198796 (US9221796, 88) Show SMILES Oc1ccc(cc1)[C@H]1CCN(C[C@@H]1F)[C@@H]1CCN(Cc2ccc(cc2)C(F)(F)F)C1=O |r| Show InChI InChI=1S/C23H24F4N2O2/c24-20-14-28(11-9-19(20)16-3-7-18(30)8-4-16)21-10-12-29(22(21)31)13-15-1-5-17(6-2-15)23(25,26)27/h1-8,19-21,30H,9-14H2/t19-,20+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.30	-51.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198697 (US9221796, 25b) Show SMILES Oc1ccc(CN2CC[C@@H](N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C22H26N2O3/c25-19-5-1-16(2-6-19)15-24-14-11-21(22(24)27)23-12-9-18(10-13-23)17-3-7-20(26)8-4-17/h1-8,18,21,25-26H,9-15H2/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.30	-51.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198672 (BDBM198673 | BDBM198674 | BDBM198675 | BDBM198676 ...) Show SMILES OC1CN(CCC1c1ccc(O)cc1)C1CCN(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C22H25FN2O3/c23-17-5-1-15(2-6-17)13-25-12-10-20(22(25)28)24-11-9-19(21(27)14-24)16-3-7-18(26)8-4-16/h1-8,19-21,26-27H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.70	-51.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198751 (BDBM198752 | BDBM198827 | US9221796, 53, P-1) Show SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)C1CCN(Cc2ccc(cc2)C(F)(F)F)C1=O Show InChI InChI=1S/C23H23F5N2O2/c24-22(25)14-30(11-9-19(22)16-3-7-18(31)8-4-16)20-10-12-29(21(20)32)13-15-1-5-17(6-2-15)23(26,27)28/h1-8,19-20,31H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.80	-51.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198780 (US9221796, 72) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccc(cc2)C(F)(F)F)C1=O |r| Show InChI InChI=1S/C23H24F4N2O2/c24-20-14-28(11-9-19(20)16-3-7-18(30)8-4-16)21-10-12-29(22(21)31)13-15-1-5-17(6-2-15)23(25,26)27/h1-8,19-21,30H,9-14H2/t19-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6	-50.9	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198747 (BDBM198748 | BDBM198749 | BDBM198750 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1F Show InChI InChI=1S/C23H25F3N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-21(22(27)30)28-10-8-19(23(25,26)14-28)17-4-6-18(29)7-5-17/h2-7,12,19,21,29H,8-11,13-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.20	-50.8	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198775 (US9221796, 67) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccc(Cl)c(F)c2)C1=O |r| Show InChI InChI=1S/C22H23ClF2N2O2/c23-18-6-1-14(11-19(18)24)12-27-10-8-21(22(27)29)26-9-7-17(20(25)13-26)15-2-4-16(28)5-3-15/h1-6,11,17,20-21,28H,7-10,12-13H2/t17-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.5	-50.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198747 (BDBM198748 | BDBM198749 | BDBM198750 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1F Show InChI InChI=1S/C23H25F3N2O2/c1-15-2-3-16(12-20(15)24)13-27-11-9-21(22(27)30)28-10-8-19(23(25,26)14-28)17-4-6-18(29)7-5-17/h2-7,12,19,21,29H,8-11,13-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.70	-50.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198770 (US9221796, 62) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@H]1CCN(C1=O)c1ccc(OC(F)F)c(Cl)c1 |r| Show InChI InChI=1S/C22H22ClF3N2O3/c23-17-11-14(3-6-20(17)31-22(25)26)28-10-8-19(21(28)30)27-9-7-16(18(24)12-27)13-1-4-15(29)5-2-13/h1-6,11,16,18-19,22,29H,7-10,12H2/t16-,18+,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.70	-50.6	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198743 (BDBM198744 | BDBM198745 | BDBM198746 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1 Show InChI InChI=1S/C23H26F2N2O2/c1-16-2-4-17(5-3-16)14-26-13-11-21(22(26)29)27-12-10-20(23(24,25)15-27)18-6-8-19(28)9-7-18/h2-9,20-21,28H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.60	-50.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198807 (BDBM198823 | US9221796, 96, P-2) Show SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)[C@@H]1CCN(Cc2ccc(Cl)c(F)c2)C1=O |r| Show InChI InChI=1S/C22H22ClF3N2O2/c23-18-6-1-14(11-19(18)24)12-27-10-8-20(21(27)30)28-9-7-17(22(25,26)13-28)15-2-4-16(29)5-3-15/h1-6,11,17,20,29H,7-10,12-13H2/t17?,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.70	-50.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198783 (US9221796, 75) Show SMILES Oc1ccc(cc1)[C@H]1CCN(C[C@@H]1F)[C@@H]1CCN(Cc2ccccc2)C1=O |r| Show InChI InChI=1S/C22H25FN2O2/c23-20-15-24(12-10-19(20)17-6-8-18(26)9-7-17)21-11-13-25(22(21)27)14-16-4-2-1-3-5-16/h1-9,19-21,26H,10-15H2/t19-,20+,21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	-50.1	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198829 (BDBM198830 | US9221796, 112, P-1) Show SMILES Cc1ccc(CN2CCC(N3CC[C@@H]([C@H](F)C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H27FN2O2/c1-16-2-4-17(5-3-16)14-26-13-11-22(23(26)28)25-12-10-20(21(24)15-25)18-6-8-19(27)9-7-18/h2-9,20-22,27H,10-15H2,1H3/t20-,21-,22?/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.40	-50.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198753 (BDBM198754 | BDBM198755 | BDBM198756 | US9221796, ...) Show SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)C1CCN(Cc2ccc(F)cc2)C1=O Show InChI InChI=1S/C22H23F3N2O2/c23-17-5-1-15(2-6-17)13-26-12-10-20(21(26)29)27-11-9-19(22(24,25)14-27)16-3-7-18(28)8-4-16/h1-8,19-20,28H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.5	-49.9	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198766 (US9221796, 58) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccccc2)C1=O |r| Show InChI InChI=1S/C22H25FN2O2/c23-20-15-24(12-10-19(20)17-6-8-18(26)9-7-17)21-11-13-25(22(21)27)14-16-4-2-1-3-5-16/h1-9,19-21,26H,10-15H2/t19-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.70	-49.9	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198771 (US9221796, 63) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(C1=O)c1ccc(OC(F)F)c(Cl)c1 |r| Show InChI InChI=1S/C22H22ClF3N2O3/c23-17-11-14(3-6-20(17)31-22(25)26)28-10-8-19(21(28)30)27-9-7-16(18(24)12-27)13-1-4-15(29)5-2-13/h1-6,11,16,18-19,22,29H,7-10,12H2/t16-,18+,19+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10	-49.5	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198701 (US9221796, 28b) Show SMILES Cc1ccc(CN2CC[C@@H](N3CC(C3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C21H24N2O2/c1-15-2-4-16(5-3-15)12-22-11-10-20(21(22)25)23-13-18(14-23)17-6-8-19(24)9-7-17/h2-9,18,20,24H,10-14H2,1H3/t20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10	-49.5	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198743 (BDBM198744 | BDBM198745 | BDBM198746 | US9221796, ...) Show SMILES Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)C(F)(F)C3)C2=O)cc1 Show InChI InChI=1S/C23H26F2N2O2/c1-16-2-4-17(5-3-16)14-26-13-11-21(22(26)29)27-12-10-20(23(24,25)15-27)18-6-8-19(28)9-7-18/h2-9,20-21,28H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	-49.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198814 (US9221796, 101, P-2) Show SMILES Oc1ccc(cc1)C1CCN(CC1(F)F)[C@@H]1CCN(C1=O)c1ccc(OC(F)F)c(Cl)c1 |r| Show InChI InChI=1S/C22H21ClF4N2O3/c23-17-11-14(3-6-19(17)32-21(24)25)29-10-8-18(20(29)31)28-9-7-16(22(26,27)12-28)13-1-4-15(30)5-2-13/h1-6,11,16,18,21,30H,7-10,12H2/t16?,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	-49.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198735 (US9221796, 48, P-3) Show SMILES Oc1ccc(cc1)[C@@H]1CCN(C[C@H]1F)[C@@H]1CCN(Cc2ccc(F)cc2)C1=O |r| Show InChI InChI=1S/C22H24F2N2O2/c23-17-5-1-15(2-6-17)13-26-12-10-21(22(26)28)25-11-9-19(20(24)14-25)16-3-7-18(27)8-4-16/h1-8,19-21,27H,9-14H2/t19-,20+,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	-49.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198693 (US9221796, 23a) Show SMILES Cc1ccc(CN2CC[C@H](N3CCC(CC3)c3ccc(O)cc3)C2=O)cc1 |r| Show InChI InChI=1S/C23H28N2O2/c1-17-2-4-18(5-3-17)16-25-15-12-22(23(25)27)24-13-10-20(11-14-24)19-6-8-21(26)9-7-19/h2-9,20,22,26H,10-16H2,1H3/t22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	11	-49.2	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM198683 (US9221796, 15) Show SMILES Oc1ccc(cc1)C1CCN(CC1)C1CCN(Cc2ccc(Cl)c(F)c2)C1=O Show InChI InChI=1S/C22H24ClFN2O2/c23-19-6-1-15(13-20(19)24)14-26-12-9-21(22(26)28)25-10-7-17(8-11-25)16-2-4-18(27)5-3-16/h1-6,13,17,21,27H,7-12,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	12	-49.0	n/a	n/a	n/a	n/a	n/a	n/a	50
Bristol-Myers Squibb Company US Patent					Assay Description To perform the competition binding assay, thawed membrane homogenate was added to each well of a 96-well plate (20 ug/well). The experimental compo...				US Patent US9221796 (2015) BindingDB Entry DOI: 10.7270/Q20V8BK1
					More data for this Ligand-Target Pair

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