Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199410 (US9221831, 75) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0140 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199350 (US9221831, 15) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0200 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199363 (US9221831, 28) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0400 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199407 (US9221831, 72) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0500 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199419 (US9221831, 85) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199418 (US9221831, 84) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199404 (US9221831, 69) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199357 (US9221831, 22) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199353 (US9221831, 18) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM4203 (US8530494, 6 | US9221831, 10) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199346 (US9221831, 11) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199411 (US9221831, 76) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199425 (US9221831, 91) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199420 (US9221831, 86) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199366 (US9221831, 31) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199365 (US9221831, 30) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199361 (US9221831, 26) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199356 (US9221831, 21) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM199419 (US9221831, 85) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.150 | -60.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199409 (US9221831, 74) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.150 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199340 (US9221831, 4) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM199418 (US9221831, 84) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.190 | -60.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199408 (US9221831, 73) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199339 (US9221831, 3) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199354 (US9221831, 19) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199338 (US9221831, 2) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.280 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199396 (US9221831, 61) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.290 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM199411 (US9221831, 76) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.340 | -58.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199364 (US9221831, 29) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199367 (US9221831, 32) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199337 (US9221831, 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199351 (US9221831, 16) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199399 (US9221831, 64) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199415 (US9221831, 80) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 0.730 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM199346 (US9221831, 11) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.930 | -55.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199400 (US9221831, 65) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 0.930 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199414 (US9221831, 79) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 1.02 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199386 (US9221831, 51) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.07 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199424 (US9221831, 90) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.11 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199416 (US9221831, 82) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 1.16 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM199409 (US9221831, 74) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.17 | -55.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Delta-type opioid receptor (Homo sapiens (Human)) | BDBM199418 (US9221831, 84) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 1.23 | -50.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purdue Pharma, L.P. US Patent | Assay Description Delta-opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displacement assays used 0.3 nM [3H]-Naltrindole (Perkin... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM199357 (US9221831, 22) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.33 | -54.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199383 (US9221831, 48) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.37 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199402 (US9221831, 67) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.39 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM199420 (US9221831, 86) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | 1.40 | -54.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM4203 (US8530494, 6 | US9221831, 10) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.52 | -54.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 50 |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose-displacement binding assays for t-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199403 (US9221831, 68) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.57 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199406 (US9221831, 71) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.58 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM199376 (US9221831, 41) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.71 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma, L.P. US Patent | Assay Description Radioligand dose displacement assays used 0.4 nM [3H]-U69,593 (GE Healthcare, Piscataway, N.J.; 40 Ci/mmole) with 15 μg membrane protein (recomb... | US Patent US9221831 (2015) BindingDB Entry DOI: 10.7270/Q2T72G8M | |||||||||||
More data for this Ligand-Target Pair |
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