Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM203919 (US9242988, 1) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ... | US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM203913 (US9242988, 22) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ... | US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM203915 (US9242988, 24) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 87 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ... | US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM203914 (US9242988, 23) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ... | US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM203918 (US9242988, 27) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ... | US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM203916 (US9242988, 25) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ... | US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Genome polyprotein (Hepatitis C virus genotype 1b (isolate BK) (HCV)) | BDBM203917 (US9242988, 26) | PDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | KEGG PC cid PC sid UniChem | US Patent | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.3 | 25 |
Merck Sharp & Dohme Corp. US Patent | Assay Description To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ... | US Patent US9242988 (2016) BindingDB Entry DOI: 10.7270/Q22B8WVP | |||||||||||
More data for this Ligand-Target Pair |