Compile Data Set for Download or QSAR

Found 800 hits Enz. Inhib. hit(s) with all data for entry = 7974   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226864 (US9328096, 557) Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C28H20Cl2FN7O2/c29-20-13-21(30)19(12-18(20)26-22(31)7-4-9-34-26)27(39)36-25-14-23(37-38(25)17-5-2-1-3-6-17)28(40)35-15-16-8-10-33-24(32)11-16/h1-14H,15H2,(H2,32,33)(H,35,40)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.02	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM227148 (US9328096, 836) Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C28H20ClF2N7O2/c29-20-13-22(31)19(26-21(30)7-4-9-34-26)12-18(20)27(39)36-25-14-23(37-38(25)17-5-2-1-3-6-17)28(40)35-15-16-8-10-33-24(32)11-16/h1-14H,15H2,(H2,32,33)(H,35,40)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.04	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226929 (US9328096, 617) Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C28H21Cl2N7O2/c29-21-14-22(30)20(13-19(21)23-8-4-5-10-32-23)27(38)35-26-15-24(36-37(26)18-6-2-1-3-7-18)28(39)34-16-17-9-11-33-25(31)12-17/h1-15H,16H2,(H2,31,33)(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.17	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226759 (US9328096, 452) Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ccc(F)cn3)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C28H20Cl2FN7O2/c29-21-12-22(30)20(11-19(21)23-7-6-17(31)15-34-23)27(39)36-26-13-24(37-38(26)18-4-2-1-3-5-18)28(40)35-14-16-8-9-33-25(32)10-16/h1-13,15H,14H2,(H2,32,33)(H,35,40)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.43	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226847 (US9328096, 540) Show SMILES Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C26H18Cl2FN7O2/c1-14-22(13-31-34-14)32-26(38)21-12-23(36(35-21)15-6-3-2-4-7-15)33-25(37)17-10-16(18(27)11-19(17)28)24-20(29)8-5-9-30-24/h2-13H,1H3,(H,31,34)(H,32,38)(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.51	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226527 (US9328096, 220) Show SMILES Cc1n[nH]c(C)c1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ccccn2)n(n1)-c1ccccc1 Show InChI InChI=1S/C27H21Cl2N7O2/c1-15-25(16(2)34-33-15)32-27(38)23-14-24(36(35-23)17-8-4-3-5-9-17)31-26(37)19-12-18(20(28)13-21(19)29)22-10-6-7-11-30-22/h3-14H,1-2H3,(H,31,37)(H,32,38)(H,33,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.71	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226611 (US9328096, 304) Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C28H21ClFN7O2/c29-21-14-22(30)20(23-8-4-5-10-32-23)13-19(21)27(38)35-26-15-24(36-37(26)18-6-2-1-3-7-18)28(39)34-16-17-9-11-33-25(31)12-17/h1-15H,16H2,(H2,31,33)(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.71	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226486 (US9328096, 179) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cn[nH]c2)c(Cl)cc1Cl Show InChI InChI=1S/C26H18Cl2FN7O2/c27-19-10-20(28)18(9-17(19)24-21(29)7-4-8-30-24)25(37)34-23-11-22(26(38)31-12-15-13-32-33-14-15)35-36(23)16-5-2-1-3-6-16/h1-11,13-14H,12H2,(H,31,38)(H,32,33)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.74	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226998 (US9328096, 686) Show SMILES CNc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)cn1 Show InChI InChI=1S/C29H23ClFN7O2/c1-32-26-11-10-18(16-34-26)17-35-29(40)25-15-27(38(37-25)19-7-3-2-4-8-19)36-28(39)20-13-21(23(31)14-22(20)30)24-9-5-6-12-33-24/h2-16H,17H2,1H3,(H,32,34)(H,35,40)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.77	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226353 (US9328096, 46) Show SMILES Clc1cc(Cl)c(cc1C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cn[nH]c1)-c1ccccn1 Show InChI InChI=1S/C26H19Cl2N7O2/c27-20-11-21(28)19(10-18(20)22-8-4-5-9-29-22)25(36)33-24-12-23(26(37)30-13-16-14-31-32-15-16)34-35(24)17-6-2-1-3-7-17/h1-12,14-15H,13H2,(H,30,37)(H,31,32)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.81	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226346 (US9328096, 39) Show SMILES Fc1cc(Cl)c(cc1-c1ncccc1F)C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cn[nH]c1 Show InChI InChI=1S/C26H18ClF2N7O2/c27-19-10-21(29)18(24-20(28)7-4-8-30-24)9-17(19)25(37)34-23-11-22(26(38)31-12-15-13-32-33-14-15)35-36(23)16-5-2-1-3-6-16/h1-11,13-14H,12H2,(H,31,38)(H,32,33)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.94	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM227052 (US9328096, 740) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cncnc2)c(Cl)cc1Cl Show InChI InChI=1S/C27H18Cl2FN7O2/c28-20-10-21(29)19(9-18(20)25-22(30)7-4-8-33-25)26(38)35-24-11-23(36-37(24)17-5-2-1-3-6-17)27(39)34-14-16-12-31-15-32-13-16/h1-13,15H,14H2,(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.02	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226514 (US9328096, 207) Show SMILES Nc1cccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)n1 Show InChI InChI=1S/C28H20ClF2N7O2/c29-20-13-22(31)19(26-21(30)9-5-11-33-26)12-18(20)27(39)36-25-14-23(37-38(25)17-7-2-1-3-8-17)28(40)34-15-16-6-4-10-24(32)35-16/h1-14H,15H2,(H2,32,35)(H,34,40)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.06	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226999 (US9328096, 687) Show SMILES Oc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)nc1 Show InChI InChI=1S/C28H20ClFN6O3/c29-22-13-23(30)21(24-8-4-5-11-31-24)12-20(22)27(38)34-26-14-25(35-36(26)18-6-2-1-3-7-18)28(39)33-15-17-9-10-19(37)16-32-17/h1-14,16,37H,15H2,(H,33,39)(H,34,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.27	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226472 (US9328096, 165) Show SMILES Cc1n[nH]c(C)c1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C27H20Cl2FN7O2/c1-14-24(15(2)35-34-14)33-27(39)22-13-23(37(36-22)16-7-4-3-5-8-16)32-26(38)18-11-17(19(28)12-20(18)29)25-21(30)9-6-10-31-25/h3-13H,1-2H3,(H,32,38)(H,33,39)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.45	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226881 (US9328096, 574) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2ccno2)c(Cl)cc1Cl Show InChI InChI=1S/C26H17Cl2FN6O3/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-9-30-24)25(36)33-23-13-22(26(37)31-14-16-8-10-32-38-16)34-35(23)15-5-2-1-3-6-15/h1-13H,14H2,(H,31,37)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.46	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226481 (US9328096, 174) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cn[nH]n2)c(Cl)cc1Cl Show InChI InChI=1S/C25H17Cl2FN8O2/c26-18-10-19(27)17(9-16(18)23-20(28)7-4-8-29-23)24(37)32-22-11-21(25(38)30-12-14-13-31-35-33-14)34-36(22)15-5-2-1-3-6-15/h1-11,13H,12H2,(H,30,38)(H,32,37)(H,31,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.53	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226483 (US9328096, 176) Show SMILES Fc1ccc(nc1)-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cn[nH]c2)c(Cl)cc1Cl Show InChI InChI=1S/C26H18Cl2FN7O2/c27-20-9-21(28)19(8-18(20)22-7-6-16(29)14-30-22)25(37)34-24-10-23(26(38)31-11-15-12-32-33-13-15)35-36(24)17-4-2-1-3-5-17/h1-10,12-14H,11H2,(H,31,38)(H,32,33)(H,34,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226992 (US9328096, 680) Show SMILES Cc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)c(N)n1 Show InChI InChI=1S/C29H23ClFN7O2/c1-17-10-11-18(27(32)35-17)16-34-29(40)25-15-26(38(37-25)19-7-3-2-4-8-19)36-28(39)20-13-21(23(31)14-22(20)30)24-9-5-6-12-33-24/h2-15H,16H2,1H3,(H2,32,35)(H,34,40)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.65	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226487 (US9328096, 180) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cc[nH]n2)c(Cl)cc1Cl Show InChI InChI=1S/C26H18Cl2FN7O2/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-9-30-24)25(37)33-23-13-22(26(38)31-14-15-8-10-32-34-15)35-36(23)16-5-2-1-3-6-16/h1-13H,14H2,(H,31,38)(H,32,34)(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226807 (US9328096, 500) Show SMILES Cc1n[nH]c(C)c1NC(=O)c1cc(NC(=O)c2cc(c(F)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C27H20ClF2N7O2/c1-14-24(15(2)35-34-14)33-27(39)22-13-23(37(36-22)16-7-4-3-5-8-16)32-26(38)17-11-18(21(30)12-19(17)28)25-20(29)9-6-10-31-25/h3-13H,1-2H3,(H,32,38)(H,33,39)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.84	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226729 (US9328096, 422) Show SMILES CC1(O)CCC(CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ccc(F)cn2)n(n1)-c1ccccc1 |(-.04,-4.73,;-1.47,-5.31,;-.19,-6.17,;-2.1,-3.9,;-3.63,-3.74,;-4.53,-4.98,;-3.91,-6.39,;-2.38,-6.55,;-6.07,-4.82,;-6.69,-3.42,;-8.22,-3.25,;-5.79,-2.17,;-4.25,-2.17,;-3.77,-.71,;-2.31,-.23,;-1.16,-1.26,;-1.48,-2.77,;.3,-.78,;1.45,-1.81,;2.91,-1.34,;3.23,.17,;4.7,.64,;2.09,1.2,;.62,.72,;-.52,1.75,;4.06,-2.37,;5.52,-1.89,;6.67,-2.92,;6.34,-4.43,;7.49,-5.46,;4.88,-4.91,;3.74,-3.88,;-5.02,.2,;-6.26,-.71,;-5.02,1.74,;-6.35,2.51,;-6.35,4.05,;-5.02,4.82,;-3.68,4.05,;-3.68,2.51,)| Show InChI InChI=1S/C29H26Cl2FN5O3/c1-29(40)11-9-18(10-12-29)34-28(39)25-15-26(37(36-25)19-5-3-2-4-6-19)35-27(38)21-13-20(22(30)14-23(21)31)24-8-7-17(32)16-33-24/h2-8,13-16,18,40H,9-12H2,1H3,(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.96	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226458 (US9328096, 151) Show SMILES Nc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)cn1 Show InChI InChI=1S/C28H20ClF2N7O2/c29-20-12-22(31)19(26-21(30)7-4-10-33-26)11-18(20)27(39)36-25-13-23(37-38(25)17-5-2-1-3-6-17)28(40)35-15-16-8-9-24(32)34-14-16/h1-14H,15H2,(H2,32,34)(H,35,40)(H,36,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.98	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226485 (US9328096, 178) Show SMILES Fc1cc(Cl)c(cc1-c1ccccn1)C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cn[nH]c1 Show InChI InChI=1S/C26H19ClFN7O2/c27-20-11-21(28)19(22-8-4-5-9-29-22)10-18(20)25(36)33-24-12-23(26(37)30-13-16-14-31-32-15-16)34-35(24)17-6-2-1-3-7-17/h1-12,14-15H,13H2,(H,30,37)(H,31,32)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.05	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226347 (US9328096, 40) Show SMILES Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(c(F)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C26H18ClF2N7O2/c1-14-22(13-31-34-14)32-26(38)21-12-23(36(35-21)15-6-3-2-4-7-15)33-25(37)16-10-17(20(29)11-18(16)27)24-19(28)8-5-9-30-24/h2-13H,1H3,(H,31,34)(H,32,38)(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.17	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226882 (US9328096, 575) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2cccnn2)c(Cl)cc1Cl Show InChI InChI=1S/C27H18Cl2FN7O2/c28-20-13-21(29)19(12-18(20)25-22(30)9-5-10-31-25)26(38)34-24-14-23(36-37(24)17-7-2-1-3-8-17)27(39)32-15-16-6-4-11-33-35-16/h1-14H,15H2,(H,32,39)(H,34,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.21	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226874 (US9328096, 567) Show SMILES Cn1cc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)nn1 Show InChI InChI=1S/C26H19Cl2FN8O2/c1-36-14-15(33-35-36)13-31-26(39)22-12-23(37(34-22)16-6-3-2-4-7-16)32-25(38)18-10-17(19(27)11-20(18)28)24-21(29)8-5-9-30-24/h2-12,14H,13H2,1H3,(H,31,39)(H,32,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.22	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM227058 (US9328096, 746) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCCC#N)c(Cl)cc1Cl Show InChI InChI=1S/C25H17Cl2FN6O2/c26-18-13-19(27)17(12-16(18)23-20(28)8-4-10-30-23)24(35)32-22-14-21(25(36)31-11-5-9-29)33-34(22)15-6-2-1-3-7-15/h1-4,6-8,10,12-14H,5,11H2,(H,31,36)(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.25	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226529 (US9328096, 222) Show SMILES Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(ccc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C28H21ClFN7O2/c29-21-9-8-18(26-22(30)7-4-11-33-26)14-20(21)27(38)35-25-15-23(36-37(25)19-5-2-1-3-6-19)28(39)34-16-17-10-12-32-24(31)13-17/h1-15H,16H2,(H2,31,32)(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.37	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226445 (US9328096, 138) Show SMILES Nc1ccc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)cn1 Show InChI InChI=1S/C28H21ClFN7O2/c29-21-13-22(30)20(23-8-4-5-11-32-23)12-19(21)27(38)35-26-14-24(36-37(26)18-6-2-1-3-7-18)28(39)34-16-17-9-10-25(31)33-15-17/h1-15H,16H2,(H2,31,33)(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.41	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226838 (US9328096, 531) Show SMILES OCC1(CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C26H20Cl2FN5O3/c27-18-12-19(28)17(11-16(18)23-20(29)7-4-10-30-23)24(36)31-22-13-21(25(37)32-26(14-35)8-9-26)33-34(22)15-5-2-1-3-6-15/h1-7,10-13,35H,8-9,14H2,(H,31,36)(H,32,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.41	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226521 (US9328096, 214) Show SMILES Fc1cc(Cl)c(cc1-c1ncccc1F)C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1cnn[nH]1 Show InChI InChI=1S/C25H17ClF2N8O2/c26-18-10-20(28)17(23-19(27)7-4-8-29-23)9-16(18)24(37)32-22-11-21(25(38)30-12-14-13-31-35-33-14)34-36(22)15-5-2-1-3-6-15/h1-11,13H,12H2,(H,30,38)(H,32,37)(H,31,33,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.63	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226352 (US9328096, 45) Show SMILES Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ccccn2)n(n1)-c1ccccc1 Show InChI InChI=1S/C26H19Cl2N7O2/c1-15-23(14-30-33-15)31-26(37)22-13-24(35(34-22)16-7-3-2-4-8-16)32-25(36)18-11-17(19(27)12-20(18)28)21-9-5-6-10-29-21/h2-14H,1H3,(H,30,33)(H,31,37)(H,32,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.92	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226865 (US9328096, 558) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NC2CC2)c(Cl)cc1Cl Show InChI InChI=1S/C25H18Cl2FN5O2/c26-18-12-19(27)17(11-16(18)23-20(28)7-4-10-29-23)24(34)31-22-13-21(25(35)30-14-8-9-14)32-33(22)15-5-2-1-3-6-15/h1-7,10-14H,8-9H2,(H,30,35)(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.02	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226477 (US9328096, 170) Show SMILES O[C@H]1CC[C@@H](CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 |wU:4.7,wD:1.0,(.23,-5.74,;-1.3,-5.57,;-1.93,-4.17,;-3.46,-4.01,;-4.36,-5.25,;-3.74,-6.66,;-2.2,-6.82,;-5.89,-5.09,;-6.52,-3.69,;-8.05,-3.52,;-5.62,-2.44,;-4.08,-2.44,;-3.6,-.97,;-2.14,-.5,;-.99,-1.53,;-1.31,-3.04,;.47,-1.05,;1.62,-2.08,;3.08,-1.61,;3.4,-.1,;4.87,.37,;2.26,.93,;.79,.45,;-.35,1.48,;4.23,-2.64,;3.91,-4.14,;5.05,-5.18,;6.52,-4.7,;6.84,-3.19,;5.69,-2.16,;6.01,-.66,;-4.85,-.07,;-6.09,-.97,;-4.85,1.47,;-6.18,2.24,;-6.18,3.78,;-4.85,4.55,;-3.51,3.78,;-3.51,2.24,)| Show InChI InChI=1S/C28H24Cl2FN5O3/c29-21-14-22(30)20(13-19(21)26-23(31)7-4-12-32-26)27(38)34-25-15-24(35-36(25)17-5-2-1-3-6-17)28(39)33-16-8-10-18(37)11-9-16/h1-7,12-16,18,37H,8-11H2,(H,33,39)(H,34,38)/t16-,18-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.03	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226853 (US9328096, 546) Show SMILES OCC1(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)COC1 Show InChI InChI=1S/C27H22Cl2FN5O4/c28-19-10-20(29)18(9-17(19)24-21(30)7-4-8-31-24)25(37)33-23-11-22(34-35(23)16-5-2-1-3-6-16)26(38)32-12-27(13-36)14-39-15-27/h1-11,36H,12-15H2,(H,32,38)(H,33,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.14	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226476 (US9328096, 169) Show SMILES OC1(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)COC1 Show InChI InChI=1S/C26H20Cl2FN5O4/c27-18-10-19(28)17(9-16(18)23-20(29)7-4-8-30-23)24(35)32-22-11-21(25(36)31-12-26(37)13-38-14-26)33-34(22)15-5-2-1-3-6-15/h1-11,37H,12-14H2,(H,31,36)(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.22	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226879 (US9328096, 572) Show SMILES OCCCNC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C25H20Cl2FN5O3/c26-18-13-19(27)17(12-16(18)23-20(28)8-4-9-29-23)24(35)31-22-14-21(25(36)30-10-5-11-34)32-33(22)15-6-2-1-3-7-15/h1-4,6-9,12-14,34H,5,10-11H2,(H,30,36)(H,31,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.36	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226862 (US9328096, 555) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)N[C@@H]2CCOC2)c(Cl)cc1Cl Show InChI InChI=1S/C26H20Cl2FN5O3/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-9-30-24)25(35)32-23-13-22(26(36)31-15-8-10-37-14-15)33-34(23)16-5-2-1-3-6-16/h1-7,9,11-13,15H,8,10,14H2,(H,31,36)(H,32,35)/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.41	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226845 (US9328096, 538) Show SMILES O[C@H]1CC[C@H](CC1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 |wU:1.0,4.7,(.23,-5.74,;-1.3,-5.57,;-2.2,-6.82,;-3.74,-6.66,;-4.36,-5.25,;-3.46,-4.01,;-1.93,-4.17,;-5.89,-5.09,;-6.52,-3.69,;-8.05,-3.52,;-5.62,-2.44,;-4.08,-2.44,;-3.6,-.97,;-2.14,-.5,;-.99,-1.53,;-1.31,-3.04,;.47,-1.05,;1.62,-2.08,;3.08,-1.61,;3.4,-.1,;4.87,.37,;2.26,.93,;.79,.45,;-.35,1.48,;4.23,-2.64,;3.91,-4.14,;5.05,-5.18,;6.52,-4.7,;6.84,-3.19,;5.69,-2.16,;6.01,-.66,;-4.85,-.07,;-6.09,-.97,;-4.85,1.47,;-6.18,2.24,;-6.18,3.78,;-4.85,4.55,;-3.51,3.78,;-3.51,2.24,)| Show InChI InChI=1S/C28H24Cl2FN5O3/c29-21-14-22(30)20(13-19(21)26-23(31)7-4-12-32-26)27(38)34-25-15-24(35-36(25)17-5-2-1-3-6-17)28(39)33-16-8-10-18(37)11-9-16/h1-7,12-16,18,37H,8-11H2,(H,33,39)(H,34,38)/t16-,18+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.46	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM227054 (US9328096, 742) Show SMILES CC(CO)CNC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C26H22Cl2FN5O3/c1-15(14-35)13-31-26(37)22-12-23(34(33-22)16-6-3-2-4-7-16)32-25(36)18-10-17(19(27)11-20(18)28)24-21(29)8-5-9-30-24/h2-12,15,35H,13-14H2,1H3,(H,31,37)(H,32,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM227000 (US9328096, 688) Show SMILES COc1cc(CNC(=O)c2cc(NC(=O)c3cc(c(F)cc3Cl)-c3ccccn3)n(n2)-c2ccccc2)ccn1 Show InChI InChI=1S/C29H22ClFN6O3/c1-40-27-13-18(10-12-33-27)17-34-29(39)25-16-26(37(36-25)19-7-3-2-4-8-19)35-28(38)20-14-21(23(31)15-22(20)30)24-9-5-6-11-32-24/h2-16H,17H2,1H3,(H,34,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.56	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226441 (US9328096, 134) Show SMILES CC(C)(C)CNC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C27H24Cl2FN5O2/c1-27(2,3)15-32-26(37)22-14-23(35(34-22)16-8-5-4-6-9-16)33-25(36)18-12-17(19(28)13-20(18)29)24-21(30)10-7-11-31-24/h4-14H,15H2,1-3H3,(H,32,37)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.61	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226856 (US9328096, 549) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCC2CCOC2)c(Cl)cc1Cl Show InChI InChI=1S/C27H22Cl2FN5O3/c28-20-12-21(29)19(11-18(20)25-22(30)7-4-9-31-25)26(36)33-24-13-23(27(37)32-14-16-8-10-38-15-16)34-35(24)17-5-2-1-3-6-17/h1-7,9,11-13,16H,8,10,14-15H2,(H,32,37)(H,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.66	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226494 (US9328096, 187) Show SMILES Clc1cc(Cl)c(cc1C(=O)Nc1cc(nn1-c1ccccc1)C(=O)NCc1ccno1)-c1ccccn1 Show InChI InChI=1S/C26H18Cl2N6O3/c27-20-13-21(28)19(12-18(20)22-8-4-5-10-29-22)25(35)32-24-14-23(26(36)30-15-17-9-11-31-37-17)33-34(24)16-6-2-1-3-7-16/h1-14H,15H2,(H,30,36)(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.67	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226866 (US9328096, 559) Show SMILES Fc1cccnc1-c1cc(C(=O)Nc2cc(nn2-c2ccccc2)C(=O)NCc2ccncn2)c(Cl)cc1Cl Show InChI InChI=1S/C27H18Cl2FN7O2/c28-20-12-21(29)19(11-18(20)25-22(30)7-4-9-32-25)26(38)35-24-13-23(36-37(24)17-5-2-1-3-6-17)27(39)33-14-16-8-10-31-15-34-16/h1-13,15H,14H2,(H,33,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.68	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226850 (US9328096, 543) Show SMILES O[C@H]1C[C@@H](C1)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 |wU:3.5,wD:1.0,(-5.13,-2.63,;-5.13,-1.09,;-4.04,-0,;-5.13,1.09,;-6.22,-0,;-5.13,2.63,;-3.8,3.4,;-3.8,4.94,;-2.46,2.63,;-2.3,1.09,;-.79,.77,;-.17,-.63,;-1.07,-1.88,;-2.6,-1.72,;-.45,-3.29,;-1.35,-4.53,;-.73,-5.94,;.81,-6.1,;1.43,-7.51,;1.71,-4.85,;1.08,-3.45,;1.99,-2.2,;-1.63,-7.18,;-3.16,-7.02,;-4.07,-8.27,;-3.44,-9.68,;-1.91,-9.84,;-1,-8.59,;.53,-8.75,;-.02,2.11,;-1.06,3.25,;1.51,2.27,;2.13,3.68,;3.66,3.84,;4.57,2.59,;3.94,1.18,;2.41,1.02,)| Show InChI InChI=1S/C26H20Cl2FN5O3/c27-19-12-20(28)18(11-17(19)24-21(29)7-4-8-30-24)25(36)32-23-13-22(26(37)31-14-9-16(35)10-14)33-34(23)15-5-2-1-3-6-15/h1-8,11-14,16,35H,9-10H2,(H,31,37)(H,32,36)/t14-,16-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.69	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226465 (US9328096, 158) Show SMILES Cc1ncc(CNC(=O)c2cc(NC(=O)c3cc(c(Cl)cc3Cl)-c3ncccc3F)n(n2)-c2ccccc2)[nH]1 Show InChI InChI=1S/C27H20Cl2FN7O2/c1-15-32-13-16(34-15)14-33-27(39)23-12-24(37(36-23)17-6-3-2-4-7-17)35-26(38)19-10-18(20(28)11-21(19)29)25-22(30)8-5-9-31-25/h2-13H,14H2,1H3,(H,32,34)(H,33,39)(H,35,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.71	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226460 (US9328096, 153) Show SMILES O[C@@H]1COC[C@H]1NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C26H20Cl2FN5O4/c27-17-10-18(28)16(9-15(17)24-19(29)7-4-8-30-24)25(36)32-23-11-20(26(37)31-21-12-38-13-22(21)35)33-34(23)14-5-2-1-3-6-14/h1-11,21-22,35H,12-13H2,(H,31,37)(H,32,36)/t21-,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.72	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor [441-796] (Homo sapiens (Human))	BDBM226877 (US9328096, 570) Show SMILES C[C@@H](CO)NC(=O)c1cc(NC(=O)c2cc(c(Cl)cc2Cl)-c2ncccc2F)n(n1)-c1ccccc1 Show InChI InChI=1S/C25H20Cl2FN5O3/c1-14(13-34)30-25(36)21-12-22(33(32-21)15-6-3-2-4-7-15)31-24(35)17-10-16(18(26)11-19(17)27)23-20(28)8-5-9-29-23/h2-12,14,34H,13H2,1H3,(H,30,36)(H,31,35)/t14-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.73	n/a	n/a	n/a	n/a	n/a	37
Pfizer Inc. US Patent					Assay Description TRKA co-expressed with p75: The assays are based upon DiscoveRx's proprietary Enzyme Fragment Complementation (EFC) technology. In the case of the TR...				US Patent US9328096 (2016) BindingDB Entry DOI: 10.7270/Q2FN152J
					More data for this Ligand-Target Pair

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