BindingDB PrimarySearch

Found 56 hits Enz. Inhib. hit(s) with all data for entry = 2565
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22097 (6-{[(3,4-dichlorophenyl)methyl]amino}-9-(3-hydroxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22087 (6-{[(4-chlorophenyl)methyl]amino}-9-(3-hydroxyprop...) Show SMILES OCCCn1cnc2c(NCc3ccc(Cl)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22100 (6-{[(3,4-dichlorophenyl)methyl]amino}-9-[3-(methox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22099 (6-{[(3,4-dichlorophenyl)methyl]amino}-9-(5-hydroxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22098 (6-{[(3,4-dichlorophenyl)methyl]amino}-9-(2,3-dihyd...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22094 (6-{[(3,4-dichlorophenyl)methyl]amino}-9-(2-hydroxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22051 (9-benzyl-6-(cyclohexylamino)-9H-purine-2-carbonitr...) Show SMILES N#Cc1nc(NC2CCCCC2)c2ncn(Cc3ccccc3)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22101 (6-{[(3,4-dichlorophenyl)methyl]amino}-9-(3-methoxy...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22082 (6-(benzylamino)-9-{[3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22063 (9-benzyl-6-{[(3-methylphenyl)methyl]amino}-9H-puri...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22085 (9-benzyl-6-{[(4-fluorophenyl)methyl]amino}-9H-puri...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22102 (6-{[(3,4-dichlorophenyl)methyl]amino}-9-(3,3-dimet...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22095 (9-butyl-6-{[(3,4-dichlorophenyl)methyl]amino}-9H-p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22076 (9-(3-hydroxypropyl)-6-{[(4-methylphenyl)methyl]ami...) Show SMILES Cc1ccc(CNc2nc(nc3n(CCCO)cnc23)C#N)cc1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22075 (9-benzyl-6-{[(4-methoxyphenyl)methyl]amino}-9H-pur...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22088 (6-{[(4-chlorophenyl)methyl]amino}-9-(4-hydroxybuty...) Show SMILES OCCCCn1cnc2c(NCc3ccc(Cl)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22048 (9-benzyl-6-{[(2S)-2-methylbutyl]amino}-9H-purine-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22074 (9-butyl-6-{[(4-methoxyphenyl)methyl]amino}-9H-puri...) Show SMILES CCCCn1cnc2c(NCc3ccc(OC)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22066 (9-benzyl-6-(benzylamino)-9H-purine-2-carbonitrile ...) Show SMILES N#Cc1nc(NCc2ccccc2)c2ncn(Cc3ccccc3)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22059 (9-cyclopentyl-6-{[(4-methoxyphenyl)methyl]amino}-9...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22084 (9-butyl-6-{[(4-fluorophenyl)methyl]amino}-9H-purin...) Show SMILES CCCCn1cnc2c(NCc3ccc(F)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22050 (9-cyclohexyl-6-(cyclohexylamino)-9H-purine-2-carbo...) Show SMILES N#Cc1nc(NC2CCCCC2)c2ncn(C3CCCCC3)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22049 (6-(cyclohexylamino)-9-propyl-9H-purine-2-carbonitr...) Show SMILES CCCn1cnc2c(NC3CCCCC3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22091 (6-{[(4-bromophenyl)methyl]amino}-9-butyl-9H-purine...) Show SMILES CCCCn1cnc2c(NCc3ccc(Br)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22067 (9-butyl-6-{[(4-chlorophenyl)methyl]amino}-9H-purin...) Show SMILES CCCCn1cnc2c(NCc3ccc(Cl)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22071 (6-[(2-phenylethyl)amino]-9-(pyridin-3-ylmethyl)-9H...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22060 (9-butyl-6-{[(3-methylphenyl)methyl]amino}-9H-purin...) Show SMILES CCCCn1cnc2c(NCc3cccc(C)c3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22080 (6-(benzylamino)-9-(oxan-2-ylmethyl)-9H-purine-2-ca...) Show SMILES N#Cc1nc(NCc2ccccc2)c2ncn(CC3CCCCO3)c2n1 Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22081 (6-(benzylamino)-9-[(4-methoxyphenyl)methyl]-9H-pur...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22079 (6-(benzylamino)-9-(3-hydroxypropyl)-9H-purine-2-ca...) Show SMILES OCCCn1cnc2c(NCc3ccccc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22064 (6-(benzylamino)-9-butyl-9H-purine-2-carbonitrile \|...) Show SMILES CCCCn1cnc2c(NCc3ccccc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22046 (9-cyclopentyl-6-{[(2S)-2-methylbutyl]amino}-9H-pur...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22096 (9-benzyl-6-{[(3,4-dichlorophenyl)methyl]amino}-9H-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22072 (9-butyl-6-[(2-phenylethyl)amino]-9H-purine-2-carbo...) Show SMILES CCCCn1cnc2c(NCCc3ccccc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22083 (6-{[(4-fluorophenyl)methyl]amino}-9-(4-hydroxybuty...) Show SMILES OCCCCn1cnc2c(NCc3ccc(F)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22068 (6-{[(4-chlorophenyl)methyl]amino}-9-cyclopentyl-9H...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22089 (6-{[(4-chlorophenyl)methyl]amino}-9-[(4-methoxyphe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22092 (9-benzyl-6-{[(4-bromophenyl)methyl]amino}-9H-purin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22090 (6-{[(4-chlorophenyl)methyl]amino}-9-{[3-(trifluoro...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22086 (6-{[(4-chlorophenyl)methyl]amino}-9-(pyridin-3-ylm...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22078 (9-benzyl-6-{[(4-methylphenyl)methyl]amino}-9H-puri...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22077 (9-butyl-6-{[(4-methylphenyl)methyl]amino}-9H-purin...) Show SMILES CCCCn1cnc2c(NCc3ccc(C)cc3)nc(nc12)C#N Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22073 (9-benzyl-6-[(2-phenylethyl)amino]-9H-purine-2-carb...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22070 (9-benzyl-6-{[(4-chlorophenyl)methyl]amino}-9H-puri...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22069 (6-{[(4-chlorophenyl)methyl]amino}-9-(cyclohexylmet...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22093 (6-{[(4-bromophenyl)methyl]amino}-9-(3-phenylpropyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	25
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22062 (9-(cyclohexylmethyl)-6-{[(3-methylphenyl)methyl]am...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22061 (9-cyclopentyl-6-{[(3-methylphenyl)methyl]amino}-9H...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22058 (9-benzyl-6-{[(1R)-1-phenylethyl]amino}-9H-purine-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair
Cathepsin B-like cysteine protease (Trypanosoma brucei)	BDBM22057 (9-cyclopentyl-6-{[(1R)-1-phenylethyl]amino}-9H-pur...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	5.5	22
University of California at San Francisco					Assay Description Enzyme activity was assayed in a 96-well plate format. TbcatB was incubated with inhibitor compound at room temperature for 20 min before the additio...				J Med Chem 51: 545-52 (2008) Article DOI: 10.1021/jm070760l BindingDB Entry DOI: 10.7270/Q2V40SH0
University of California at San Francisco					More data for this Ligand-Target Pair

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