Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 7 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 7 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 7 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 7 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 13 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 13 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 13 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 163 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 13 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 164 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 13 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 174 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 13 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 179 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 3 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 240 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 3 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 254 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 260 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 3 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 437 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 3 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | 510 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 3 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 534 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 3 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 537 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 1 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 1 + BH (Homo sapiens (Human)) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 1.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
University of Tampere and Tampere University Hospital | Assay Description Reactions were measured using 0.2 mM phenol red (Absmax at 557 nm) as the indicator, in 10 mM HEPES, 0.1 M Na2SO4, pH 7.5, for a period of 10-100 s. ... | J Enzyme Inhib Med Chem 26: 862-70 (2011) Article DOI: 10.3109/14756366.2011.588227 BindingDB Entry DOI: 10.7270/Q2S181DX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |