Compile Data Set for Download or QSAR

Found 56 hits Enz. Inhib. hit(s) with all data for entry = 8250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor XI (Homo sapiens (Human))	BDBM238267 (US9394250, 99) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)C1CCC(CC1)C(N)=N)N1CCN(CC1)S(C)(=O)=O |r,wU:19.36,17.18,(10.48,2.25,;9.14,3.02,;7.81,2.25,;7.81,.71,;6.48,3.02,;5.14,2.25,;5.14,.71,;3.81,-.06,;2.47,.71,;2.47,2.25,;3.81,3.02,;1.14,-.06,;-.32,.41,;-1.23,-.83,;-.32,-2.08,;1.14,-1.6,;2.47,-2.37,;-2.56,-.53,;-3.04,.93,;-4.58,.93,;-5.05,-.53,;-3.81,-1.44,;-3.81,-2.98,;-2.47,-3.75,;-5.14,-3.75,;-6.48,-2.98,;-7.81,-3.75,;-7.81,-5.29,;-6.48,-6.06,;-5.14,-5.29,;-9.14,-6.06,;-9.14,-7.6,;-10.48,-5.29,;-5.35,2.26,;-4.58,3.6,;-5.35,4.93,;-6.89,4.93,;-7.66,3.6,;-6.89,2.26,;-7.66,6.27,;-8.43,7.6,;-6.32,7.04,;-8.99,5.5,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238259 (US10336741, Example 71 | US10882855, Example 71 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238268 (US10336741, Example 98 | US10882855, Example 98 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)N1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238252 (US10336741, Example 20 | US10882855, Example 20 | ...) Show SMILES CS(=O)(=O)N1CCN(CC1)[C@H]1C[C@H](N(C1)C(=O)c1ccc(cc1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H30N6O6S/c1-38(36,37)30-12-10-29(11-13-30)20-14-21(23(32)28-19-8-6-18(7-9-19)25(34)35)31(15-20)24(33)17-4-2-16(3-5-17)22(26)27/h2-9,20-21H,10-15H2,1H3,(H3,26,27)(H,28,32)(H,34,35)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238266 (US10882855, Example 96 | US9394250, 96 | US9585881...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)[C@H]1CC[C@H](CN)CC1)C1CCN(CC1)S(C)(=O)=O |r,wU:19.35,17.18,27.30,wD:24.26,(10.54,.13,;9.2,.9,;7.87,.13,;7.87,-1.41,;6.54,.9,;5.2,.13,;5.2,-1.41,;3.87,-2.18,;2.54,-1.41,;2.54,.13,;3.87,.9,;1.2,-2.18,;-.04,-1.27,;-1.29,-2.18,;-.81,-3.64,;.73,-3.64,;1.5,-4.98,;-2.62,-1.41,;-3.1,.06,;-4.64,.06,;-5.12,-1.41,;-3.87,-2.31,;-3.87,-3.85,;-2.54,-4.62,;-5.2,-4.62,;-6.54,-3.85,;-7.87,-4.62,;-7.87,-6.16,;-9.2,-6.93,;-10.54,-6.16,;-6.54,-6.93,;-5.2,-6.16,;-5.41,1.39,;-4.64,2.72,;-5.41,4.06,;-6.95,4.06,;-7.72,2.72,;-6.95,1.39,;-7.72,5.39,;-9.26,5.39,;-7.72,6.93,;-6.39,6.16,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238260 (US10336741, Example 73 | US10882855, Example 73 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)c1ccc(cc1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238263 (US10336741, Example 88 | US10882855, Example 88 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)N1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238265 (US10336741, Example 94 | US10882855, Example 94 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238261 (US10336741, Example 79 | US10882855, Example 79 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)c1ccc(NC(N)=N)cc1)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238258 (US10882855, Example 69 | US9394250, 69 | US9585881...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238269 (US10336741, Example 111 | US10882855, Example 111 ...) Show SMILES CS(=O)(=O)N1CCC(CC1)[C@H]1C[C@H](N(C1)C(=O)c1ccc(cc1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H31N5O6S/c1-38(36,37)30-12-10-16(11-13-30)20-14-22(24(32)29-21-8-6-19(7-9-21)26(34)35)31(15-20)25(33)18-4-2-17(3-5-18)23(27)28/h2-9,16,20,22H,10-15H2,1H3,(H3,27,28)(H,29,32)(H,34,35)/t20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238262 (US9394250, 86) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)[C@H]1CCC(CC1)[C@H](C)N)C1CCN(CC1)S(C)(=O)=O |r,wU:19.36,17.18,wD:24.26,30.35,30.34,(10.68,-1.49,;9.59,-.4,;8.1,-.8,;7.7,-2.29,;7.01,.29,;5.52,-.11,;5.13,-1.6,;3.64,-1.99,;2.55,-.91,;2.95,.58,;4.44,.98,;1.06,-1.3,;-.18,-.4,;-1.43,-1.3,;-.95,-2.77,;.59,-2.77,;1.36,-4.1,;-2.76,-.53,;-3.24,.93,;-4.78,.93,;-5.26,-.53,;-4.01,-1.44,;-4.01,-2.98,;-2.68,-3.75,;-5.34,-3.75,;-6.68,-2.98,;-8.01,-3.75,;-8.01,-5.29,;-6.68,-6.06,;-5.34,-5.29,;-9.34,-6.06,;-9.34,-7.6,;-10.68,-5.29,;-5.55,2.26,;-4.78,3.6,;-5.55,4.93,;-7.09,4.93,;-7.86,3.6,;-7.09,2.26,;-7.86,6.27,;-8.63,7.6,;-6.53,7.04,;-9.19,5.5,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238255 (US10336741, Example 43 | US10882855, Example 43 | ...) Show SMILES Clc1ccc(c(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)Nc2ccc3nn[nH]c3c2)N2CCOCC2)c1)-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238253 (US10336741, Example 37 | US10882855, Example 37 | ...) Show SMILES OC(=O)c1ccc(NC(=O)[C@@H]2C[C@@H](CN2C(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)N2CCOCC2)cc1 |r| Show InChI InChI=1S/C26H26ClN7O5/c27-19-4-7-22(34-16-28-30-31-34)18(13-19)3-8-24(35)33-15-21(32-9-11-39-12-10-32)14-23(33)25(36)29-20-5-1-17(2-6-20)26(37)38/h1-8,13,16,21,23H,9-12,14-15H2,(H,29,36)(H,37,38)/b8-3+/t21-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238256 (US10336741, Example 55 | US10882855, Example 55 | ...) Show SMILES NC[C@H]1CC[C@@H](CC1)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)N1CCN(CC1)S(=O)(=O)C1CC1 |r,wU:2.1,12.29,14.16,wD:5.8,(-7.93,-8.37,;-7.93,-6.83,;-6.6,-6.06,;-6.6,-4.52,;-5.26,-3.75,;-3.93,-4.52,;-3.93,-6.06,;-5.26,-6.83,;-2.6,-3.75,;-1.26,-4.52,;-2.6,-2.21,;-3.84,-1.3,;-3.37,.16,;-1.83,.16,;-1.35,-1.3,;-.02,-2.07,;-.02,-3.61,;1.32,-1.3,;2.65,-2.07,;3.98,-1.3,;5.32,-2.07,;5.37,-3.64,;3.98,-4.38,;2.65,-3.61,;6.7,-4.41,;6.7,-5.95,;8.03,-3.64,;-4.14,1.49,;-3.37,2.83,;-4.14,4.16,;-5.68,4.16,;-6.45,2.83,;-5.68,1.49,;-6.45,5.5,;-7.99,5.5,;-4.91,5.5,;-5.68,6.83,;-4.34,7.6,;-5.68,8.37,)| Show InChI InChI=1S/C27H39N5O6S/c28-16-18-1-3-19(4-2-18)26(34)32-17-22(30-11-13-31(14-12-30)39(37,38)23-9-10-23)15-24(32)25(33)29-21-7-5-20(6-8-21)27(35)36/h5-8,18-19,22-24H,1-4,9-17,28H2,(H,29,33)(H,35,36)/t18-,19-,22-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238251 (US10336741, Example 9 | US10882855, Example 9 | US...) Show SMILES CS(=O)(=O)N1CCN(CC1)[C@H]1C[C@H](N(C1)C(=O)C1CCN(CC1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H35N7O6S/c1-38(36,37)30-12-10-28(11-13-30)19-14-20(21(32)27-18-4-2-17(3-5-18)23(34)35)31(15-19)22(33)16-6-8-29(9-7-16)24(25)26/h2-5,16,19-20H,6-15H2,1H3,(H3,25,26)(H,27,32)(H,34,35)/t19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238264 (US10336741, Example 93 | US10882855, Example 93 | ...) Show SMILES Cn1cc(Cl)c2c(F)c(ccc12)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)C1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C28H30ClFN4O6S/c1-32-15-21(29)24-22(32)8-7-20(25(24)30)27(36)34-14-18(16-9-11-33(12-10-16)41(2,39)40)13-23(34)26(35)31-19-5-3-17(4-6-19)28(37)38/h3-8,15-16,18,23H,9-14H2,1-2H3,(H,31,35)(H,37,38)/t18-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238257 (US10336741, Example 57 | US10882855, Example 57 | ...) Show SMILES C[C@H]1CN(CCN1S(N)(=O)=O)[C@H]1C[C@H](N(C1)C(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C26H30ClN9O4S/c1-18-15-33(11-12-36(18)41(28,39)40)22-14-24(26(38)30-21-5-3-2-4-6-21)34(16-22)25(37)10-7-19-13-20(27)8-9-23(19)35-17-29-31-32-35/h2-10,13,17-18,22,24H,11-12,14-16H2,1H3,(H,30,38)(H2,28,39,40)/b10-7+/t18-,22-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor XI (Homo sapiens (Human))	BDBM238254 (US10882855, Example 39 | US9394250, 39 | US9585881...) Show SMILES Clc1ccc(c(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)Nc2ccccc2)N2CCN(CC2)S(=O)(=O)c2ccccc2)c1)-n1cnnn1 |r| Show InChI InChI=1S/C31H31ClN8O4S/c32-24-12-13-28(40-22-33-35-36-40)23(19-24)11-14-30(41)39-21-26(20-29(39)31(42)34-25-7-3-1-4-8-25)37-15-17-38(18-16-37)45(43,44)27-9-5-2-6-10-27/h1-14,19,22,26,29H,15-18,20-21H2,(H,34,42)/b14-11+/t26-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor XIa (Haematologic Technologies Inc.) activity was measured at an enzyme concentration of 0.1 U/mL in 150 mM NaCl, 5 mM KCl, 1 mg/mL PEG6...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238265 (US10336741, Example 94 | US10882855, Example 94 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238265 (US10336741, Example 94 | US10882855, Example 94 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238260 (US10336741, Example 73 | US10882855, Example 73 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)c1ccc(cc1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238261 (US10336741, Example 79 | US10882855, Example 79 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)c1ccc(NC(N)=N)cc1)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238263 (US10336741, Example 88 | US10882855, Example 88 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)N1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238267 (US9394250, 99) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)C1CCC(CC1)C(N)=N)N1CCN(CC1)S(C)(=O)=O |r,wU:19.36,17.18,(10.48,2.25,;9.14,3.02,;7.81,2.25,;7.81,.71,;6.48,3.02,;5.14,2.25,;5.14,.71,;3.81,-.06,;2.47,.71,;2.47,2.25,;3.81,3.02,;1.14,-.06,;-.32,.41,;-1.23,-.83,;-.32,-2.08,;1.14,-1.6,;2.47,-2.37,;-2.56,-.53,;-3.04,.93,;-4.58,.93,;-5.05,-.53,;-3.81,-1.44,;-3.81,-2.98,;-2.47,-3.75,;-5.14,-3.75,;-6.48,-2.98,;-7.81,-3.75,;-7.81,-5.29,;-6.48,-6.06,;-5.14,-5.29,;-9.14,-6.06,;-9.14,-7.6,;-10.48,-5.29,;-5.35,2.26,;-4.58,3.6,;-5.35,4.93,;-6.89,4.93,;-7.66,3.6,;-6.89,2.26,;-7.66,6.27,;-8.43,7.6,;-6.32,7.04,;-8.99,5.5,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238259 (US10336741, Example 71 | US10882855, Example 71 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238258 (US10882855, Example 69 | US9394250, 69 | US9585881...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238267 (US9394250, 99) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)C1CCC(CC1)C(N)=N)N1CCN(CC1)S(C)(=O)=O |r,wU:19.36,17.18,(10.48,2.25,;9.14,3.02,;7.81,2.25,;7.81,.71,;6.48,3.02,;5.14,2.25,;5.14,.71,;3.81,-.06,;2.47,.71,;2.47,2.25,;3.81,3.02,;1.14,-.06,;-.32,.41,;-1.23,-.83,;-.32,-2.08,;1.14,-1.6,;2.47,-2.37,;-2.56,-.53,;-3.04,.93,;-4.58,.93,;-5.05,-.53,;-3.81,-1.44,;-3.81,-2.98,;-2.47,-3.75,;-5.14,-3.75,;-6.48,-2.98,;-7.81,-3.75,;-7.81,-5.29,;-6.48,-6.06,;-5.14,-5.29,;-9.14,-6.06,;-9.14,-7.6,;-10.48,-5.29,;-5.35,2.26,;-4.58,3.6,;-5.35,4.93,;-6.89,4.93,;-7.66,3.6,;-6.89,2.26,;-7.66,6.27,;-8.43,7.6,;-6.32,7.04,;-8.99,5.5,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238262 (US9394250, 86) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)[C@H]1CCC(CC1)[C@H](C)N)C1CCN(CC1)S(C)(=O)=O |r,wU:19.36,17.18,wD:24.26,30.35,30.34,(10.68,-1.49,;9.59,-.4,;8.1,-.8,;7.7,-2.29,;7.01,.29,;5.52,-.11,;5.13,-1.6,;3.64,-1.99,;2.55,-.91,;2.95,.58,;4.44,.98,;1.06,-1.3,;-.18,-.4,;-1.43,-1.3,;-.95,-2.77,;.59,-2.77,;1.36,-4.1,;-2.76,-.53,;-3.24,.93,;-4.78,.93,;-5.26,-.53,;-4.01,-1.44,;-4.01,-2.98,;-2.68,-3.75,;-5.34,-3.75,;-6.68,-2.98,;-8.01,-3.75,;-8.01,-5.29,;-6.68,-6.06,;-5.34,-5.29,;-9.34,-6.06,;-9.34,-7.6,;-10.68,-5.29,;-5.55,2.26,;-4.78,3.6,;-5.55,4.93,;-7.09,4.93,;-7.86,3.6,;-7.09,2.26,;-7.86,6.27,;-8.63,7.6,;-6.53,7.04,;-9.19,5.5,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238264 (US10336741, Example 93 | US10882855, Example 93 | ...) Show SMILES Cn1cc(Cl)c2c(F)c(ccc12)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)C1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C28H30ClFN4O6S/c1-32-15-21(29)24-22(32)8-7-20(25(24)30)27(36)34-14-18(16-9-11-33(12-10-16)41(2,39)40)13-23(34)26(35)31-19-5-3-17(4-6-19)28(37)38/h3-8,15-16,18,23H,9-14H2,1-2H3,(H,31,35)(H,37,38)/t18-,23-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238252 (US10336741, Example 20 | US10882855, Example 20 | ...) Show SMILES CS(=O)(=O)N1CCN(CC1)[C@H]1C[C@H](N(C1)C(=O)c1ccc(cc1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H30N6O6S/c1-38(36,37)30-12-10-29(11-13-30)20-14-21(23(32)28-19-8-6-18(7-9-19)25(34)35)31(15-20)24(33)17-4-2-16(3-5-17)22(26)27/h2-9,20-21H,10-15H2,1H3,(H3,26,27)(H,28,32)(H,34,35)/t20-,21-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238266 (US10882855, Example 96 | US9394250, 96 | US9585881...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)[C@H]1CC[C@H](CN)CC1)C1CCN(CC1)S(C)(=O)=O |r,wU:19.35,17.18,27.30,wD:24.26,(10.54,.13,;9.2,.9,;7.87,.13,;7.87,-1.41,;6.54,.9,;5.2,.13,;5.2,-1.41,;3.87,-2.18,;2.54,-1.41,;2.54,.13,;3.87,.9,;1.2,-2.18,;-.04,-1.27,;-1.29,-2.18,;-.81,-3.64,;.73,-3.64,;1.5,-4.98,;-2.62,-1.41,;-3.1,.06,;-4.64,.06,;-5.12,-1.41,;-3.87,-2.31,;-3.87,-3.85,;-2.54,-4.62,;-5.2,-4.62,;-6.54,-3.85,;-7.87,-4.62,;-7.87,-6.16,;-9.2,-6.93,;-10.54,-6.16,;-6.54,-6.93,;-5.2,-6.16,;-5.41,1.39,;-4.64,2.72,;-5.41,4.06,;-6.95,4.06,;-7.72,2.72,;-6.95,1.39,;-7.72,5.39,;-9.26,5.39,;-7.72,6.93,;-6.39,6.16,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238268 (US10336741, Example 98 | US10882855, Example 98 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)N1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238269 (US10336741, Example 111 | US10882855, Example 111 ...) Show SMILES CS(=O)(=O)N1CCC(CC1)[C@H]1C[C@H](N(C1)C(=O)c1ccc(cc1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H31N5O6S/c1-38(36,37)30-12-10-16(11-13-30)20-14-22(24(32)29-21-8-6-19(7-9-21)26(34)35)31(15-20)25(33)18-4-2-17(3-5-18)23(27)28/h2-9,16,20,22H,10-15H2,1H3,(H3,27,28)(H,29,32)(H,34,35)/t20-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238251 (US10336741, Example 9 | US10882855, Example 9 | US...) Show SMILES CS(=O)(=O)N1CCN(CC1)[C@H]1C[C@H](N(C1)C(=O)C1CCN(CC1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H35N7O6S/c1-38(36,37)30-12-10-28(11-13-30)19-14-20(21(32)27-18-4-2-17(3-5-18)23(34)35)31(15-19)22(33)16-6-8-29(9-7-16)24(25)26/h2-5,16,19-20H,6-15H2,1H3,(H3,25,26)(H,27,32)(H,34,35)/t19-,20-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238252 (US10336741, Example 20 | US10882855, Example 20 | ...) Show SMILES CS(=O)(=O)N1CCN(CC1)[C@H]1C[C@H](N(C1)C(=O)c1ccc(cc1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C25H30N6O6S/c1-38(36,37)30-12-10-29(11-13-30)20-14-21(23(32)28-19-8-6-18(7-9-19)25(34)35)31(15-20)24(33)17-4-2-16(3-5-17)22(26)27/h2-9,20-21H,10-15H2,1H3,(H3,26,27)(H,28,32)(H,34,35)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238253 (US10336741, Example 37 | US10882855, Example 37 | ...) Show SMILES OC(=O)c1ccc(NC(=O)[C@@H]2C[C@@H](CN2C(=O)\C=C\c2cc(Cl)ccc2-n2cnnn2)N2CCOCC2)cc1 |r| Show InChI InChI=1S/C26H26ClN7O5/c27-19-4-7-22(34-16-28-30-31-34)18(13-19)3-8-24(35)33-15-21(32-9-11-39-12-10-32)14-23(33)25(36)29-20-5-1-17(2-6-20)26(37)38/h1-8,13,16,21,23H,9-12,14-15H2,(H,29,36)(H,37,38)/b8-3+/t21-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238254 (US10882855, Example 39 | US9394250, 39 | US9585881...) Show SMILES Clc1ccc(c(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)Nc2ccccc2)N2CCN(CC2)S(=O)(=O)c2ccccc2)c1)-n1cnnn1 |r| Show InChI InChI=1S/C31H31ClN8O4S/c32-24-12-13-28(40-22-33-35-36-40)23(19-24)11-14-30(41)39-21-26(20-29(39)31(42)34-25-7-3-1-4-8-25)37-15-17-38(18-16-37)45(43,44)27-9-5-2-6-10-27/h1-14,19,22,26,29H,15-18,20-21H2,(H,34,42)/b14-11+/t26-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238255 (US10336741, Example 43 | US10882855, Example 43 | ...) Show SMILES Clc1ccc(c(\C=C\C(=O)N2C[C@H](C[C@H]2C(=O)Nc2ccc3nn[nH]c3c2)N2CCOCC2)c1)-n1cnnn1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238256 (US10336741, Example 55 | US10882855, Example 55 | ...) Show SMILES NC[C@H]1CC[C@@H](CC1)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)N1CCN(CC1)S(=O)(=O)C1CC1 |r,wU:2.1,12.29,14.16,wD:5.8,(-7.93,-8.37,;-7.93,-6.83,;-6.6,-6.06,;-6.6,-4.52,;-5.26,-3.75,;-3.93,-4.52,;-3.93,-6.06,;-5.26,-6.83,;-2.6,-3.75,;-1.26,-4.52,;-2.6,-2.21,;-3.84,-1.3,;-3.37,.16,;-1.83,.16,;-1.35,-1.3,;-.02,-2.07,;-.02,-3.61,;1.32,-1.3,;2.65,-2.07,;3.98,-1.3,;5.32,-2.07,;5.37,-3.64,;3.98,-4.38,;2.65,-3.61,;6.7,-4.41,;6.7,-5.95,;8.03,-3.64,;-4.14,1.49,;-3.37,2.83,;-4.14,4.16,;-5.68,4.16,;-6.45,2.83,;-5.68,1.49,;-6.45,5.5,;-7.99,5.5,;-4.91,5.5,;-5.68,6.83,;-4.34,7.6,;-5.68,8.37,)| Show InChI InChI=1S/C27H39N5O6S/c28-16-18-1-3-19(4-2-18)26(34)32-17-22(30-11-13-31(14-12-30)39(37,38)23-9-10-23)15-24(32)25(33)29-21-7-5-20(6-8-21)27(35)36/h5-8,18-19,22-24H,1-4,9-17,28H2,(H,29,33)(H,35,36)/t18-,19-,22-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238257 (US10336741, Example 57 | US10882855, Example 57 | ...) Show SMILES C[C@H]1CN(CCN1S(N)(=O)=O)[C@H]1C[C@H](N(C1)C(=O)\C=C\c1cc(Cl)ccc1-n1cnnn1)C(=O)Nc1ccccc1 |r| Show InChI InChI=1S/C26H30ClN9O4S/c1-18-15-33(11-12-36(18)41(28,39)40)22-14-24(26(38)30-21-5-3-2-4-6-21)34(16-22)25(37)10-7-19-13-20(27)8-9-23(19)35-17-29-31-32-35/h2-10,13,17-18,22,24H,11-12,14-16H2,1H3,(H,30,38)(H2,28,39,40)/b10-7+/t18-,22-,24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238258 (US10882855, Example 69 | US9394250, 69 | US9585881...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238260 (US10336741, Example 73 | US10882855, Example 73 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)c1ccc(cc1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238261 (US10336741, Example 79 | US10882855, Example 79 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)c1ccc(NC(N)=N)cc1)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238262 (US9394250, 86) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)[C@H]1CCC(CC1)[C@H](C)N)C1CCN(CC1)S(C)(=O)=O |r,wU:19.36,17.18,wD:24.26,30.35,30.34,(10.68,-1.49,;9.59,-.4,;8.1,-.8,;7.7,-2.29,;7.01,.29,;5.52,-.11,;5.13,-1.6,;3.64,-1.99,;2.55,-.91,;2.95,.58,;4.44,.98,;1.06,-1.3,;-.18,-.4,;-1.43,-1.3,;-.95,-2.77,;.59,-2.77,;1.36,-4.1,;-2.76,-.53,;-3.24,.93,;-4.78,.93,;-5.26,-.53,;-4.01,-1.44,;-4.01,-2.98,;-2.68,-3.75,;-5.34,-3.75,;-6.68,-2.98,;-8.01,-3.75,;-8.01,-5.29,;-6.68,-6.06,;-5.34,-5.29,;-9.34,-6.06,;-9.34,-7.6,;-10.68,-5.29,;-5.55,2.26,;-4.78,3.6,;-5.55,4.93,;-7.09,4.93,;-7.86,3.6,;-7.09,2.26,;-7.86,6.27,;-8.63,7.6,;-6.53,7.04,;-9.19,5.5,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238263 (US10336741, Example 88 | US10882855, Example 88 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)N1CCN(CC1)C(N)=N)C1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238264 (US10336741, Example 93 | US10882855, Example 93 | ...) Show SMILES Cn1cc(Cl)c2c(F)c(ccc12)C(=O)N1C[C@H](C[C@H]1C(=O)Nc1ccc(cc1)C(O)=O)C1CCN(CC1)S(C)(=O)=O |r| Show InChI InChI=1S/C28H30ClFN4O6S/c1-32-15-21(29)24-22(32)8-7-20(25(24)30)27(36)34-14-18(16-9-11-33(12-10-16)41(2,39)40)13-23(34)26(35)31-19-5-3-17(4-6-19)28(37)38/h3-8,15-16,18,23H,9-14H2,1-2H3,(H,31,35)(H,37,38)/t18-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM238251 (US10336741, Example 9 | US10882855, Example 9 | US...) Show SMILES CS(=O)(=O)N1CCN(CC1)[C@H]1C[C@H](N(C1)C(=O)C1CCN(CC1)C(N)=N)C(=O)Nc1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C24H35N7O6S/c1-38(36,37)30-12-10-28(11-13-30)19-14-20(21(32)27-18-4-2-17(3-5-18)23(34)35)31(15-19)22(33)16-6-8-29(9-7-16)24(25)26/h2-5,16,19-20H,6-15H2,1H3,(H3,25,26)(H,27,32)(H,34,35)/t19-,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238266 (US10882855, Example 96 | US9394250, 96 | US9585881...) Show SMILES COC(=O)Nc1ccc(cc1)-c1[nH]c(nc1Cl)[C@@H]1C[C@@H](CN1C(=O)[C@H]1CC[C@H](CN)CC1)C1CCN(CC1)S(C)(=O)=O |r,wU:19.35,17.18,27.30,wD:24.26,(10.54,.13,;9.2,.9,;7.87,.13,;7.87,-1.41,;6.54,.9,;5.2,.13,;5.2,-1.41,;3.87,-2.18,;2.54,-1.41,;2.54,.13,;3.87,.9,;1.2,-2.18,;-.04,-1.27,;-1.29,-2.18,;-.81,-3.64,;.73,-3.64,;1.5,-4.98,;-2.62,-1.41,;-3.1,.06,;-4.64,.06,;-5.12,-1.41,;-3.87,-2.31,;-3.87,-3.85,;-2.54,-4.62,;-5.2,-4.62,;-6.54,-3.85,;-7.87,-4.62,;-7.87,-6.16,;-9.2,-6.93,;-10.54,-6.16,;-6.54,-6.93,;-5.2,-6.16,;-5.41,1.39,;-4.64,2.72,;-5.41,4.06,;-6.95,4.06,;-7.72,2.72,;-6.95,1.39,;-7.72,5.39,;-9.26,5.39,;-7.72,6.93,;-6.39,6.16,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM238268 (US10336741, Example 98 | US10882855, Example 98 | ...) Show SMILES COC(=O)Nc1ccc(cc1)-c1cnc([nH]1)[C@@H]1C[C@@H](CN1C(=O)C1CCN(CC1)C(N)=N)N1CCN(CC1)S(C)(=O)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
ONO PHARMACEUTICAL CO., LTD. US Patent					Assay Description Human Factor Xa (American Diagnostica Inc.) and human thrombin (Sigma) activities were measured at the enzyme concentrations of 0.18 U/mL and 0.12 U/...				US Patent US9394250 (2016) BindingDB Entry DOI: 10.7270/Q2222SP5
					More data for this Ligand-Target Pair

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