Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 5B, mitochondrial (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 21 | -43.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 13 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 23 | -43.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 7 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | DrugBank Article PubMed | 26 | -43.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | DrugBank MMDB PDB Article PubMed | 38 | -42.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 50 | -41.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 50 | -41.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 6 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 79 | -40.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 340 | -36.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 4 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 510 | -35.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 630 | -35.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 13 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 690 | -35.2 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 5B, mitochondrial (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 740 | -35.0 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 3 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 760 | -34.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 6 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 860 | -34.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 980 | -34.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.14E+3 | -33.9 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | DrugBank Article PubMed | 1.20E+3 | -33.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 7 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.26E+3 | -33.7 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 14 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.47E+3 | -33.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.15E+3 | -32.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.13E+3 | -29.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM248142 (Grayanotoxin III (GTX3)) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.01E+3 | -29.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 4 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | DrugBank Article PubMed | 1.50E+4 | -27.5 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 3 (Homo sapiens (Human)) | BDBM10883 (4,5-dichlorobenzene-1,3-disulfonamide | CHEMBL17 |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents | Article PubMed | 6.80E+5 | -18.1 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Calgary | Assay Description An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of... | J Enzyme Inhib Med Chem 29: 469-75 (2014) Article DOI: 10.3109/14756366.2013.804072 BindingDB Entry DOI: 10.7270/Q24X56QZ | |||||||||||
More data for this Ligand-Target Pair |