Compile Data Set for Download or QSAR

Found 60 hits Enz. Inhib. hit(s) with all data for entry = 8532   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256293 (US9487488, 17) Show SMILES Cc1cc(ccc1-c1nnn[nH]1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H23F3N6O3S/c1-17-14-22(12-13-23(17)26-33-35-36-34-26)41(38,39)37(16-18-6-10-21(11-7-18)40-28(29,30)31)27-25(19-8-9-19)24-5-3-2-4-20(24)15-32-27/h2-7,10-15,19H,8-9,16H2,1H3,(H,33,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256277 (US9487488, 1) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C27H21F3N6O3S/c28-27(29,30)39-21-11-5-17(6-12-21)16-36(26-24(18-7-8-18)23-4-2-1-3-20(23)15-31-26)40(37,38)22-13-9-19(10-14-22)25-32-34-35-33-25/h1-6,9-15,18H,7-8,16H2,(H,32,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256299 (US9487488, 23) Show SMILES Cc1cc(ccc1-c1ncn[nH]1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H24F3N5O3S/c1-18-14-23(12-13-24(18)27-34-17-35-36-27)41(38,39)37(16-19-6-10-22(11-7-19)40-29(30,31)32)28-26(20-8-9-20)25-5-3-2-4-21(25)15-33-28/h2-7,10-15,17,20H,8-9,16H2,1H3,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256310 (US9487488, 34) Show SMILES Cc1cc(ccc1-c1noc(=O)[nH]1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H23F3N4O5S/c1-17-14-22(12-13-23(17)26-34-28(37)41-35-26)42(38,39)36(16-18-6-10-21(11-7-18)40-29(30,31)32)27-25(19-8-9-19)24-5-3-2-4-20(24)15-33-27/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256298 (US9487488, 22) Show SMILES Cc1n[nH]c(n1)-c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H24F3N5O3S/c1-18-34-27(36-35-18)21-10-14-24(15-11-21)41(38,39)37(17-19-6-12-23(13-7-19)40-29(30,31)32)28-26(20-8-9-20)25-5-3-2-4-22(25)16-33-28/h2-7,10-16,20H,8-9,17H2,1H3,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256314 (US9487488, 38) Show SMILES Cc1cc(ccc1S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1)C(O)=O Show InChI InChI=1S/C28H23F3N2O5S/c1-17-14-20(27(34)35)10-13-24(17)39(36,37)33(16-18-6-11-22(12-7-18)38-28(29,30)31)26-25(19-8-9-19)23-5-3-2-4-21(23)15-32-26/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256301 (US9487488, 25) Show SMILES Cc1n[nH]c(n1)-c1ccc(cc1)S(=O)(=O)N(Cc1ccc(cn1)C(F)(F)F)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H23F3N6O2S/c1-17-34-26(36-35-17)19-8-12-23(13-9-19)40(38,39)37(16-22-11-10-21(15-32-22)28(29,30)31)27-25(18-6-7-18)24-5-3-2-4-20(24)14-33-27/h2-5,8-15,18H,6-7,16H2,1H3,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256290 (US9487488, 14) Show SMILES Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C28H23F3N6O3S/c1-17-23-4-2-3-5-24(23)25(19-8-9-19)32-27(17)37(16-18-6-12-21(13-7-18)40-28(29,30)31)41(38,39)22-14-10-20(11-15-22)26-33-35-36-34-26/h2-7,10-15,19H,8-9,16H2,1H3,(H,33,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256278 (US9487488, 2) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(nc2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C26H20F3N7O3S/c27-26(28,29)39-19-9-5-16(6-10-19)15-36(25-23(17-7-8-17)21-4-2-1-3-18(21)13-31-25)40(37,38)20-11-12-22(30-14-20)24-32-34-35-33-24/h1-6,9-14,17H,7-8,15H2,(H,32,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256303 (US9487488, 27) Show SMILES Cc1n[nH]c(n1)-c1ccc(cc1C)S(=O)(=O)N(Cc1ccc(cn1)C(F)(F)F)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H25F3N6O2S/c1-17-13-23(11-12-24(17)27-35-18(2)36-37-27)41(39,40)38(16-22-10-9-21(15-33-22)29(30,31)32)28-26(19-7-8-19)25-6-4-3-5-20(25)14-34-28/h3-6,9-15,19H,7-8,16H2,1-2H3,(H,35,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256294 (US9487488, 18) Show SMILES FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)nc1 Show InChI InChI=1S/C26H20F3N7O2S/c27-26(28,29)19-9-10-20(30-14-19)15-36(25-23(16-5-6-16)22-4-2-1-3-18(22)13-31-25)39(37,38)21-11-7-17(8-12-21)24-32-34-35-33-24/h1-4,7-14,16H,5-6,15H2,(H,32,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256302 (US9487488, 26) Show SMILES Cc1cc(ccc1-c1ncn[nH]1)S(=O)(=O)N(Cc1ccc(cn1)C(F)(F)F)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H23F3N6O2S/c1-17-12-22(10-11-23(17)26-34-16-35-36-26)40(38,39)37(15-21-9-8-20(14-32-21)28(29,30)31)27-25(18-6-7-18)24-5-3-2-4-19(24)13-33-27/h2-5,8-14,16,18H,6-7,15H2,1H3,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256328 (US9487488, 52) Show SMILES OC(=O)c1ccc(cc1F)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C27H20F4N2O5S/c28-23-13-20(11-12-22(23)26(34)35)39(36,37)33(15-16-5-9-19(10-6-16)38-27(29,30)31)25-24(17-7-8-17)21-4-2-1-3-18(21)14-32-25/h1-6,9-14,17H,7-8,15H2,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256283 (US9487488, 7) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2noc(=O)[nH]2)cc1 Show InChI InChI=1S/C28H21F3N4O5S/c29-28(30,31)39-21-11-5-17(6-12-21)16-35(26-24(18-7-8-18)23-4-2-1-3-20(23)15-32-26)41(37,38)22-13-9-19(10-14-22)25-33-27(36)40-34-25/h1-6,9-15,18H,7-8,16H2,(H,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256285 (US9487488, 9) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(nc2)-c2noc(=O)[nH]2)cc1 Show InChI InChI=1S/C27H20F3N5O5S/c28-27(29,30)39-19-9-5-16(6-10-19)15-35(25-23(17-7-8-17)21-4-2-1-3-18(21)13-32-25)41(37,38)20-11-12-22(31-14-20)24-33-26(36)40-34-24/h1-6,9-14,17H,7-8,15H2,(H,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256280 (US9487488, 4) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cn2)-n2nn[nH]c2=O)cc1 Show InChI InChI=1S/C26H20F3N7O4S/c27-26(28,29)40-20-10-5-16(6-11-20)15-35(24-23(17-7-8-17)21-4-2-1-3-18(21)13-31-24)41(38,39)22-12-9-19(14-30-22)36-25(37)32-33-34-36/h1-6,9-14,17H,7-8,15H2,(H,32,34,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256306 (US9487488, 30) Show SMILES Cc1n[nH]c(n1)-c1ccc(cn1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H23F3N6O3S/c1-17-34-26(36-35-17)24-13-12-22(15-32-24)41(38,39)37(16-18-6-10-21(11-7-18)40-28(29,30)31)27-25(19-8-9-19)23-5-3-2-4-20(23)14-33-27/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256317 (US9487488, 41) Show SMILES CNc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H24F3N3O5S/c1-32-24-14-21(12-13-23(24)27(35)36)40(37,38)34(16-17-6-10-20(11-7-17)39-28(29,30)31)26-25(18-8-9-18)22-5-3-2-4-19(22)15-33-26/h2-7,10-15,18,32H,8-9,16H2,1H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256307 (US9487488, 31) Show SMILES FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2noc(=O)[nH]2)nc1 Show InChI InChI=1S/C27H20F3N5O4S/c28-27(29,30)19-9-10-20(31-14-19)15-35(25-23(16-5-6-16)22-4-2-1-3-18(22)13-32-25)40(37,38)21-11-7-17(8-12-21)24-33-26(36)39-34-24/h1-4,7-14,16H,5-6,15H2,(H,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256297 (US9487488, 21) Show SMILES Cc1n[nH]c(n1)-c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F Show InChI InChI=1S/C27H19F6N5O3S/c1-16-35-24(37-36-16)18-8-12-21(13-9-18)42(39,40)38(15-17-6-10-20(11-7-17)41-27(31,32)33)25-23(26(28,29)30)22-5-3-2-4-19(22)14-34-25/h2-14H,15H2,1H3,(H,35,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256300 (US9487488, 24) Show SMILES FC(F)(F)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2ncn[nH]2)nc1 Show InChI InChI=1S/C27H21F3N6O2S/c28-27(29,30)20-9-10-21(31-14-20)15-36(26-24(17-5-6-17)23-4-2-1-3-19(23)13-32-26)39(37,38)22-11-7-18(8-12-22)25-33-16-34-35-25/h1-4,7-14,16-17H,5-6,15H2,(H,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256315 (US9487488, 39) Show SMILES COCc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H25F3N2O6S/c1-39-17-21-14-23(12-13-25(21)28(35)36)41(37,38)34(16-18-6-10-22(11-7-18)40-29(30,31)32)27-26(19-8-9-19)24-5-3-2-4-20(24)15-33-27/h2-7,10-15,19H,8-9,16-17H2,1H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256312 (US9487488, 36) Show SMILES Cc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H23F3N2O5S/c1-17-14-22(12-13-23(17)27(34)35)39(36,37)33(16-18-6-10-21(11-7-18)38-28(29,30)31)26-25(19-8-9-19)24-5-3-2-4-20(24)15-32-26/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256318 (US9487488, 42) Show SMILES Cc1cc(cc(F)c1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H22F4N2O5S/c1-16-12-21(13-23(29)24(16)27(35)36)40(37,38)34(15-17-6-10-20(11-7-17)39-28(30,31)32)26-25(18-8-9-18)22-5-3-2-4-19(22)14-33-26/h2-7,10-14,18H,8-9,15H2,1H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256292 (US9487488, 16) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(nc2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C24H15F6N7O3S/c25-23(26,27)20-18-4-2-1-3-15(18)11-32-22(20)37(13-14-5-7-16(8-6-14)40-24(28,29)30)41(38,39)17-9-10-19(31-12-17)21-33-35-36-34-21/h1-12H,13H2,(H,33,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256282 (US9487488, 6) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(nc2)-c2ncn[nH]2)cc1 Show InChI InChI=1S/C27H21F3N6O3S/c28-27(29,30)39-20-9-5-17(6-10-20)15-36(26-24(18-7-8-18)22-4-2-1-3-19(22)13-32-26)40(37,38)21-11-12-23(31-14-21)25-33-16-34-35-25/h1-6,9-14,16,18H,7-8,15H2,(H,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256291 (US9487488, 15) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(cc2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C25H16F6N6O3S/c26-24(27,28)21-20-4-2-1-3-17(20)13-32-23(21)37(14-15-5-9-18(10-6-15)40-25(29,30)31)41(38,39)19-11-7-16(8-12-19)22-33-35-36-34-22/h1-13H,14H2,(H,33,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256330 (US9487488, 54) Show SMILES CCc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H25F3N2O5S/c1-2-19-15-23(13-14-25(19)28(35)36)40(37,38)34(17-18-7-11-22(12-8-18)39-29(30,31)32)27-26(20-9-10-20)24-6-4-3-5-21(24)16-33-27/h3-8,11-16,20H,2,9-10,17H2,1H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256305 (US9487488, 29) Show SMILES Cc1n[nH]c(n1)-c1ccc(cn1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F Show InChI InChI=1S/C26H18F6N6O3S/c1-15-35-23(37-36-15)21-11-10-19(13-33-21)42(39,40)38(14-16-6-8-18(9-7-16)41-26(30,31)32)24-22(25(27,28)29)20-5-3-2-4-17(20)12-34-24/h2-13H,14H2,1H3,(H,35,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256284 (US9487488, 8) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(cc2)-c2noc(=O)[nH]2)cc1 Show InChI InChI=1S/C26H16F6N4O5S/c27-25(28,29)21-20-4-2-1-3-17(20)13-33-23(21)36(14-15-5-9-18(10-6-15)40-26(30,31)32)42(38,39)19-11-7-16(8-12-19)22-34-24(37)41-35-22/h1-13H,14H2,(H,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256333 (US9487488, 57) Show SMILES CCCc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C30H27F3N2O5S/c1-2-5-21-16-24(14-15-26(21)29(36)37)41(38,39)35(18-19-8-12-23(13-9-19)40-30(31,32)33)28-27(20-10-11-20)25-7-4-3-6-22(25)17-34-28/h3-4,6-9,12-17,20H,2,5,10-11,18H2,1H3,(H,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256308 (US9487488, 32) Show SMILES Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)-c1noc(=O)[nH]1 Show InChI InChI=1S/C29H23F3N4O5S/c1-17-23-4-2-3-5-24(23)25(19-8-9-19)33-27(17)36(16-18-6-12-21(13-7-18)40-29(30,31)32)42(38,39)22-14-10-20(11-15-22)26-34-28(37)41-35-26/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256321 (US9487488, 45) Show SMILES CN(C)c1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H26F3N3O5S/c1-34(2)25-15-22(13-14-24(25)28(36)37)41(38,39)35(17-18-7-11-21(12-8-18)40-29(30,31)32)27-26(19-9-10-19)23-6-4-3-5-20(23)16-33-27/h3-8,11-16,19H,9-10,17H2,1-2H3,(H,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256329 (US9487488, 53) Show SMILES CCc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F Show InChI InChI=1S/C27H20F6N2O5S/c1-2-17-13-20(11-12-22(17)25(36)37)41(38,39)35(15-16-7-9-19(10-8-16)40-27(31,32)33)24-23(26(28,29)30)21-6-4-3-5-18(21)14-34-24/h3-14H,2,15H2,1H3,(H,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256296 (US9487488, 20) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(cc2)-c2ncn[nH]2)cc1 Show InChI InChI=1S/C26H17F6N5O3S/c27-25(28,29)22-21-4-2-1-3-18(21)13-33-24(22)37(14-16-5-9-19(10-6-16)40-26(30,31)32)41(38,39)20-11-7-17(8-12-20)23-34-15-35-36-23/h1-13,15H,14H2,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256322 (US9487488, 46) Show SMILES Cc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F Show InChI InChI=1S/C26H18F6N2O5S/c1-15-12-19(10-11-20(15)24(35)36)40(37,38)34(14-16-6-8-18(9-7-16)39-26(30,31)32)23-22(25(27,28)29)21-5-3-2-4-17(21)13-33-23/h2-13H,14H2,1H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256281 (US9487488, 5) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)-c2ncn[nH]2)cc1 Show InChI InChI=1S/C28H22F3N5O3S/c29-28(30,31)39-22-11-5-18(6-12-22)16-36(27-25(19-7-8-19)24-4-2-1-3-21(24)15-32-27)40(37,38)23-13-9-20(10-14-23)26-33-17-34-35-26/h1-6,9-15,17,19H,7-8,16H2,(H,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256304 (US9487488, 28) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(nc2)-c2ncn[nH]2)cc1 Show InChI InChI=1S/C25H16F6N6O3S/c26-24(27,28)21-19-4-2-1-3-16(19)11-33-23(21)37(13-15-5-7-17(8-6-15)40-25(29,30)31)41(38,39)18-9-10-20(32-12-18)22-34-14-35-36-22/h1-12,14H,13H2,(H,34,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256295 (US9487488, 19) Show SMILES Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)-c1ncn[nH]1 Show InChI InChI=1S/C29H24F3N5O3S/c1-18-24-4-2-3-5-25(24)26(20-8-9-20)35-28(18)37(16-19-6-12-22(13-7-19)40-29(30,31)32)41(38,39)23-14-10-21(11-15-23)27-33-17-34-36-27/h2-7,10-15,17,20H,8-9,16H2,1H3,(H,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256309 (US9487488, 33) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(nc2)-c2noc(=O)[nH]2)cc1 Show InChI InChI=1S/C25H15F6N5O5S/c26-24(27,28)20-18-4-2-1-3-15(18)11-33-22(20)36(13-14-5-7-16(8-6-14)40-25(29,30)31)42(38,39)17-9-10-19(32-12-17)21-34-23(37)41-35-21/h1-12H,13H2,(H,34,35,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256323 (US9487488, 47) Show SMILES OC(=O)c1ccc(cc1Cl)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C27H20ClF3N2O5S/c28-23-13-20(11-12-22(23)26(34)35)39(36,37)33(15-16-5-9-19(10-6-16)38-27(29,30)31)25-24(17-7-8-17)21-4-2-1-3-18(21)14-32-25/h1-6,9-14,17H,7-8,15H2,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256289 (US9487488, 13) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc3c(c2)[nH][nH]c3=O)cc1 Show InChI InChI=1S/C27H21F3N4O4S/c28-27(29,30)38-19-9-5-16(6-10-19)15-34(39(36,37)20-11-12-22-23(13-20)32-33-26(22)35)25-24(17-7-8-17)21-4-2-1-3-18(21)14-31-25/h1-6,9-14,17H,7-8,15H2,(H2,32,33,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256334 (US9487488, 58) Show SMILES OC(=O)c1ccc(cc1N1CCCC1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C31H28F3N3O5S/c32-31(33,34)42-23-11-7-20(8-12-23)19-37(29-28(21-9-10-21)25-6-2-1-5-22(25)18-35-29)43(40,41)24-13-14-26(30(38)39)27(17-24)36-15-3-4-16-36/h1-2,5-8,11-14,17-18,21H,3-4,9-10,15-16,19H2,(H,38,39)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256320 (US9487488, 44) Show SMILES CC(C)c1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C30H27F3N2O5S/c1-18(2)26-15-23(13-14-25(26)29(36)37)41(38,39)35(17-19-7-11-22(12-8-19)40-30(31,32)33)28-27(20-9-10-20)24-6-4-3-5-21(24)16-34-28/h3-8,11-16,18,20H,9-10,17H2,1-2H3,(H,36,37)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256324 (US9487488, 48) Show SMILES OC(=O)c1ccc(cc1Br)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C27H20BrF3N2O5S/c28-23-13-20(11-12-22(23)26(34)35)39(36,37)33(15-16-5-9-19(10-6-16)38-27(29,30)31)25-24(17-7-8-17)21-4-2-1-3-18(21)14-32-25/h1-6,9-14,17H,7-8,15H2,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256316 (US9487488, 40) Show SMILES Cc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1nc(C2CC2)c2ccccc2c1C Show InChI InChI=1S/C29H25F3N2O5S/c1-17-15-22(13-14-23(17)28(35)36)40(37,38)34(16-19-7-11-21(12-8-19)39-29(30,31)32)27-18(2)24-5-3-4-6-25(24)26(33-27)20-9-10-20/h3-8,11-15,20H,9-10,16H2,1-2H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256332 (US9487488, 56) Show SMILES CC(C)c1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F Show InChI InChI=1S/C28H22F6N2O5S/c1-16(2)23-13-20(11-12-22(23)26(37)38)42(39,40)36(15-17-7-9-19(10-8-17)41-28(32,33)34)25-24(27(29,30)31)21-6-4-3-5-18(21)14-35-25/h3-14,16H,15H2,1-2H3,(H,37,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256279 (US9487488, 3) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cn2)-c2nnn[nH]2)cc1 Show InChI InChI=1S/C26H20F3N7O3S/c27-26(28,29)39-20-10-5-16(6-11-20)15-36(25-23(17-7-8-17)21-4-2-1-3-18(21)13-31-25)40(37,38)22-12-9-19(14-30-22)24-32-34-35-33-24/h1-6,9-14,17H,7-8,15H2,(H,32,33,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256313 (US9487488, 37) Show SMILES Cc1cc(ccc1C(O)=O)S(=O)(=O)N(Cc1ccc(cn1)C(F)(F)F)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C27H22F3N3O4S/c1-16-12-21(10-11-22(16)26(34)35)38(36,37)33(15-20-9-8-19(14-31-20)27(28,29)30)25-24(17-6-7-17)23-5-3-2-4-18(23)13-32-25/h2-5,8-14,17H,6-7,15H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM256311 (US9487488, 35) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cn2)-c2noc(=O)[nH]2)cc1 Show InChI InChI=1S/C27H20F3N5O5S/c28-27(29,30)39-20-10-5-16(6-11-20)15-35(25-23(17-7-8-17)21-4-2-1-3-18(21)13-32-25)41(37,38)22-12-9-19(14-31-22)24-33-26(36)40-34-24/h1-6,9-14,17H,7-8,15H2,(H,33,34,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	37
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description The functional activity of a test compound was determined by measuring change in intracellular calcium concentration using a calcium sensitive fluore...				US Patent US9487488 (2016) BindingDB Entry DOI: 10.7270/Q2MG7NGT
					More data for this Ligand-Target Pair

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