BindingDB PrimarySearch

Found 20 hits Enz. Inhib. hit(s) with all data for entry = 2892
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25891 ((2S)-2-[(5-formyl-1H-pyrrol-2-yl)formamido]-3-meth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25890 ((2S)-2-[(5-formylthiophen-2-yl)formamido]-3-methyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25892 ((2S)-2-[(4-formyl-1H-pyrrol-2-yl)formamido]-3-meth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25889 ((2S)-2-[(5-formylfuran-2-yl)formamido]-3-methyl-N-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25887 ((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25894 ((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25886 ((2S)-2-(furan-2-ylformamido)-3-methyl-N-[(2S)-4-me...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25895 (N-heterocyclic dipeptide aldehyde, 13 \| methyl 5-{...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25893 ((2S)-2-[(5-formyl-1-methyl-1H-pyrrol-2-yl)formamid...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25893 ((2S)-2-[(5-formyl-1-methyl-1H-pyrrol-2-yl)formamid...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25891 ((2S)-2-[(5-formyl-1H-pyrrol-2-yl)formamido]-3-meth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25895 (N-heterocyclic dipeptide aldehyde, 13 \| methyl 5-{...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-2 catalytic subunit (Ovis aries (sheep))	BDBM25888 ((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	315	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25894 ((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25890 ((2S)-2-[(5-formylthiophen-2-yl)formamido]-3-methyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	440	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25892 ((2S)-2-[(4-formyl-1H-pyrrol-2-yl)formamido]-3-meth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25888 ((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25887 ((2S)-3-methyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25886 ((2S)-2-(furan-2-ylformamido)-3-methyl-N-[(2S)-4-me...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Ovis aries (sheep))	BDBM25889 ((2S)-2-[(5-formylfuran-2-yl)formamido]-3-methyl-N-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	7.5	25
University of Canterbury					Assay Description Calpain inhibition assays were performed in 96-well black plates. The reaction was initiated by the addition of substrate solution. The progress of t...				Bioorg Med Chem 16: 6911-23 (2008) Article DOI: 10.1016/j.bmc.2008.05.048 BindingDB Entry DOI: 10.7270/Q2C53J5R
University of Canterbury					More data for this Ligand-Target Pair