Compile Data Set for Download or QSAR

Found 43 hits Enz. Inhib. hit(s) with all data for entry = 2928   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26166 (2,4-dianilino pyrimidine, 23 | 3-({4-[(5-hydroxy-2...) Show SMILES Cc1ccc(O)cc1Nc1ccnc(Nc2cccc(c2)S(N)(=O)=O)n1 Show InChI InChI=1S/C17H17N5O3S/c1-11-5-6-13(23)10-15(11)21-16-7-8-19-17(22-16)20-12-3-2-4-14(9-12)26(18,24)25/h2-10,23H,1H3,(H2,18,24,25)(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26180 (2,4-dianilino pyrimidine, 37 | 3-({4-[(5-methyl-1H...) Show SMILES Cc1ccc2[nH]ncc2c1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C19H17N7O/c1-11-5-6-15-14(10-22-26-15)17(11)24-16-7-8-21-19(25-16)23-13-4-2-3-12(9-13)18(20)27/h2-10H,1H3,(H2,20,27)(H,22,26)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26145 (2,4-dianilino pyrimidine, 2 | 3-({4-[(5-hydroxy-2-...) Show SMILES Cc1ccc(O)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H17N5O2/c1-11-5-6-14(24)10-15(11)22-16-7-8-20-18(23-16)21-13-4-2-3-12(9-13)17(19)25/h2-10,24H,1H3,(H2,19,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26186 (2,4-dianilino pyrimidine, 43 | 3-({4-[(5-methyl-1H...) Show SMILES Cc1ccc2[nH]ncc2c1Nc1ccnc(Nc2cccc(c2)S(N)(=O)=O)n1 Show InChI InChI=1S/C18H17N7O2S/c1-11-5-6-15-14(10-21-25-15)17(11)23-16-7-8-20-18(24-16)22-12-3-2-4-13(9-12)28(19,26)27/h2-10H,1H3,(H,21,25)(H2,19,26,27)(H2,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26185 (2,4-dianilino pyrimidine, 42 | 3-{[4-(1H-indazol-4...) Show SMILES NS(=O)(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1 Show InChI InChI=1S/C17H15N7O2S/c18-27(25,26)12-4-1-3-11(9-12)21-17-19-8-7-16(23-17)22-14-5-2-6-15-13(14)10-20-24-15/h1-10H,(H,20,24)(H2,18,25,26)(H2,19,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26152 (2,4-dianilino pyrimidine, 9 | 3-({4-[(4-hydroxy-2-...) Show SMILES Cc1cc(O)ccc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H17N5O2/c1-11-9-14(24)5-6-15(11)22-16-7-8-20-18(23-16)21-13-4-2-3-12(10-13)17(19)25/h2-10,24H,1H3,(H2,19,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26149 (2,4-dianilino pyrimidine, 6 | 3-({4-[(2-bromo-5-hy...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3cc(O)ccc3Br)n2)c1 Show InChI InChI=1S/C17H14BrN5O2/c18-13-5-4-12(24)9-14(13)22-15-6-7-20-17(23-15)21-11-3-1-2-10(8-11)16(19)25/h1-9,24H,(H2,19,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26167 (2,4-dianilino pyrimidine, 24 | 3-({4-[(5-methoxy-2...) Show SMILES COc1ccc(C)c(Nc2ccnc(Nc3cccc(c3)S(N)(=O)=O)n2)c1 Show InChI InChI=1S/C18H19N5O3S/c1-12-6-7-14(26-2)11-16(12)22-17-8-9-20-18(23-17)21-13-4-3-5-15(10-13)27(19,24)25/h3-11H,1-2H3,(H2,19,24,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26182 (2,4-dianilino pyrimidine, 39 | 3-({4-[(7-methyl-1H...) Show SMILES Cc1ccc(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c2cn[nH]c12 Show InChI InChI=1S/C19H17N7O/c1-11-5-6-15(14-10-22-26-17(11)14)24-16-7-8-21-19(25-16)23-13-4-2-3-12(9-13)18(20)27/h2-10H,1H3,(H2,20,27)(H,22,26)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM25191 (4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-y...) Show SMILES Cc1ccc(O)cc1Nc1ccnc2cc(ccc12)-c1csc(C=O)n1 Show InChI InChI=1S/C20H15N3O2S/c1-12-2-4-14(25)9-17(12)22-16-6-7-21-18-8-13(3-5-15(16)18)19-11-26-20(10-24)23-19/h2-11,25H,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26147 (2,4-dianilino pyrimidine, 4 | 3-({4-[(3-hydroxy-5-...) Show SMILES Cc1cc(O)cc(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c1 Show InChI InChI=1S/C18H17N5O2/c1-11-7-14(10-15(24)8-11)21-16-5-6-20-18(23-16)22-13-4-2-3-12(9-13)17(19)25/h2-10,24H,1H3,(H2,19,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26156 (2,4-dianilino pyrimidine, 13 | 3-({4-[(5-methoxy-2...) Show SMILES COc1ccc(C)c(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c1 Show InChI InChI=1S/C19H19N5O2/c1-12-6-7-15(26-2)11-16(12)23-17-8-9-21-19(24-17)22-14-5-3-4-13(10-14)18(20)25/h3-11H,1-2H3,(H2,20,25)(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26151 (2,4-dianilino pyrimidine, 8 | 3-({4-[(2-methylphen...) Show SMILES Cc1ccccc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H17N5O/c1-12-5-2-3-8-15(12)22-16-9-10-20-18(23-16)21-14-7-4-6-13(11-14)17(19)24/h2-11H,1H3,(H2,19,24)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26157 (2,4-dianilino pyrimidine, 14 | 3-({4-[(5-amino-2-m...) Show SMILES Cc1ccc(N)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H18N6O/c1-11-5-6-13(19)10-15(11)23-16-7-8-21-18(24-16)22-14-4-2-3-12(9-14)17(20)25/h2-10H,19H2,1H3,(H2,20,25)(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26153 (2,4-dianilino pyrimidine, 10 | 3-({4-[(2-hydroxy-6...) Show SMILES Cc1cccc(O)c1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H17N5O2/c1-11-4-2-7-14(24)16(11)22-15-8-9-20-18(23-15)21-13-6-3-5-12(10-13)17(19)25/h2-10,24H,1H3,(H2,19,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26179 (2,4-dianilino pyrimidine, 36 | 3-{[4-(1H-indazol-4...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3cccc4[nH]ncc34)n2)c1 Show InChI InChI=1S/C18H15N7O/c19-17(26)11-3-1-4-12(9-11)22-18-20-8-7-16(24-18)23-14-5-2-6-15-13(14)10-21-25-15/h1-10H,(H2,19,26)(H,21,25)(H2,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26146 (2,4-dianilino pyrimidine, 3 | 3-({4-[(3-hydroxyphe...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3cccc(O)c3)n2)c1 Show InChI InChI=1S/C17H15N5O2/c18-16(24)11-3-1-4-12(9-11)21-17-19-8-7-15(22-17)20-13-5-2-6-14(23)10-13/h1-10,23H,(H2,18,24)(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26148 (2,4-dianilino pyrimidine, 5 | 3-({4-[(3-hydroxy-4-...) Show SMILES Cc1ccc(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)cc1O Show InChI InChI=1S/C18H17N5O2/c1-11-5-6-14(10-15(11)24)21-16-7-8-20-18(23-16)22-13-4-2-3-12(9-13)17(19)25/h2-10,24H,1H3,(H2,19,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26154 (2,4-dianilino pyrimidine, 11 | 3-({4-[(5-fluoro-2-...) Show SMILES Cc1ccc(F)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H16FN5O/c1-11-5-6-13(19)10-15(11)23-16-7-8-21-18(24-16)22-14-4-2-3-12(9-14)17(20)25/h2-10H,1H3,(H2,20,25)(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26168 (2,4-dianilino pyrimidine, 25 | 3-({4-[(2,4-difluor...) Show SMILES NS(=O)(=O)c1cccc(Nc2nccc(Nc3ccc(F)cc3F)n2)c1 Show InChI InChI=1S/C16H13F2N5O2S/c17-10-4-5-14(13(18)8-10)22-15-6-7-20-16(23-15)21-11-2-1-3-12(9-11)26(19,24)25/h1-9H,(H2,19,24,25)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26155 (2,4-dianilino pyrimidine, 12 | 3-({4-[(5-chloro-2-...) Show SMILES Cc1ccc(Cl)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C18H16ClN5O/c1-11-5-6-13(19)10-15(11)23-16-7-8-21-18(24-16)22-14-4-2-3-12(9-14)17(20)25/h2-10H,1H3,(H2,20,25)(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26176 (2,4-dianilino pyrimidine, 33 | 3-{[4-(1H-1,2,3-ben...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3cccc4nn[nH]c34)n2)c1 Show InChI InChI=1S/C17H14N8O/c18-16(26)10-3-1-4-11(9-10)20-17-19-8-7-14(22-17)21-12-5-2-6-13-15(12)24-25-23-13/h1-9H,(H2,18,26)(H,23,24,25)(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26181 (2,4-dianilino pyrimidine, 38 | 3-({4-[(6-methyl-1H...) Show SMILES Cc1cc(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c2cn[nH]c2c1 Show InChI InChI=1S/C19H17N7O/c1-11-7-15(14-10-22-26-16(14)8-11)24-17-5-6-21-19(25-17)23-13-4-2-3-12(9-13)18(20)27/h2-10H,1H3,(H2,20,27)(H,22,26)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26175 (2,4-dianilino pyrimidine, 32 | 3-{[4-(quinolin-5-y...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3cccc4ncccc34)n2)c1 Show InChI InChI=1S/C20H16N6O/c21-19(27)13-4-1-5-14(12-13)24-20-23-11-9-18(26-20)25-17-8-2-7-16-15(17)6-3-10-22-16/h1-12H,(H2,21,27)(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26150 (2,4-dianilino pyrimidine, 7 | 3-[(4-{[5-hydroxy-2-...) Show SMILES CC(C)c1ccc(O)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C20H21N5O2/c1-12(2)16-7-6-15(26)11-17(16)24-18-8-9-22-20(25-18)23-14-5-3-4-13(10-14)19(21)27/h3-12,26H,1-2H3,(H2,21,27)(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	880	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26165 (2,4-dianilino pyrimidine, 22 | 3-({4-[(2,4-difluor...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3ccc(F)cc3F)n2)c1 Show InChI InChI=1S/C17H13F2N5O/c18-11-4-5-14(13(19)9-11)23-15-6-7-21-17(24-15)22-12-3-1-2-10(8-12)16(20)25/h1-9H,(H2,20,25)(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26158 (2,4-dianilino pyrimidine, 15 | 3-({2-[(3-carbamoyl...) Show SMILES Cc1ccc(cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1)C(N)=O Show InChI InChI=1S/C19H18N6O2/c1-11-5-6-13(18(21)27)10-15(11)24-16-7-8-22-19(25-16)23-14-4-2-3-12(9-14)17(20)26/h2-10H,1H3,(H2,20,26)(H2,21,27)(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26177 (2,4-dianilino pyrimidine, 34 | 3-{[4-(1H-indazol-7...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3cccc4cn[nH]c34)n2)c1 Show InChI InChI=1S/C18H15N7O/c19-17(26)11-3-1-5-13(9-11)22-18-20-8-7-15(24-18)23-14-6-2-4-12-10-21-25-16(12)14/h1-10H,(H2,19,26)(H,21,25)(H2,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26183 (2,4-dianilino pyrimidine, 40 | 3-({4-[(1-methyl-1H...) Show SMILES Cn1ncc2c(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)cccc12 Show InChI InChI=1S/C19H17N7O/c1-26-16-7-3-6-15(14(16)11-22-26)24-17-8-9-21-19(25-17)23-13-5-2-4-12(10-13)18(20)27/h2-11H,1H3,(H2,20,27)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26164 (2,4-dianilino pyrimidine, 21 | 3-[(4-{[3-(N-methyl...) Show SMILES CN(C(C)=O)c1cccc(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c1 Show InChI InChI=1S/C20H20N6O2/c1-13(27)26(2)17-8-4-7-16(12-17)23-18-9-10-22-20(25-18)24-15-6-3-5-14(11-15)19(21)28/h3-12H,1-2H3,(H2,21,28)(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26172 (2,4-dianilino pyrimidine, 29 | 3-({4-[(1-methyl-1H...) Show SMILES Cn1cnc2cc(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)ccc12 Show InChI InChI=1S/C19H17N7O/c1-26-11-22-15-10-14(5-6-16(15)26)23-17-7-8-21-19(25-17)24-13-4-2-3-12(9-13)18(20)27/h2-11H,1H3,(H2,20,27)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26162 (2,4-dianilino pyrimidine, 19 | 3-({4-[(3-methoxyph...) Show SMILES COc1cccc(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c1 Show InChI InChI=1S/C18H17N5O2/c1-25-15-7-3-6-14(11-15)21-16-8-9-20-18(23-16)22-13-5-2-4-12(10-13)17(19)24/h2-11H,1H3,(H2,19,24)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26184 (2,4-dianilino pyrimidine, 41 | 3-({4-[(1,5-dimethy...) Show SMILES Cc1ccc2n(C)ncc2c1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C20H19N7O/c1-12-6-7-16-15(11-23-27(16)2)18(12)25-17-8-9-22-20(26-17)24-14-5-3-4-13(10-14)19(21)28/h3-11H,1-2H3,(H2,21,28)(H2,22,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26171 (2,4-dianilino pyrimidine, 28 | 3-{[4-(1H-indazol-5...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3ccc4[nH]ncc4c3)n2)c1 Show InChI InChI=1S/C18H15N7O/c19-17(26)11-2-1-3-13(8-11)23-18-20-7-6-16(24-18)22-14-4-5-15-12(9-14)10-21-25-15/h1-10H,(H2,19,26)(H,21,25)(H2,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26169 (2,4-dianilino pyrimidine, 26 | 3-{[4-(1,3-benzothi...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3ccc4ncsc4c3)n2)c1 Show InChI InChI=1S/C18H14N6OS/c19-17(25)11-2-1-3-12(8-11)23-18-20-7-6-16(24-18)22-13-4-5-14-15(9-13)26-10-21-14/h1-10H,(H2,19,25)(H2,20,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26163 (2,4-dianilino pyrimidine, 20 | 3-({4-[(3-fluorophe...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3cccc(F)c3)n2)c1 Show InChI InChI=1S/C17H14FN5O/c18-12-4-2-6-14(10-12)21-15-7-8-20-17(23-15)22-13-5-1-3-11(9-13)16(19)24/h1-10H,(H2,19,24)(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26161 (2,4-dianilino pyrimidine, 18 | 3-[(4-{[5-(aminomet...) Show SMILES Cc1ccc(CN)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C19H20N6O/c1-12-5-6-13(11-20)9-16(12)24-17-7-8-22-19(25-17)23-15-4-2-3-14(10-15)18(21)26/h2-10H,11,20H2,1H3,(H2,21,26)(H2,22,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26173 (2,4-dianilino pyrimidine, 30 | 3-{[4-(1H-1,2,3-ben...) Show SMILES NC(=O)c1cccc(Nc2nccc(Nc3ccc4nn[nH]c4c3)n2)c1 Show InChI InChI=1S/C17H14N8O/c18-16(26)10-2-1-3-11(8-10)21-17-19-7-6-15(22-17)20-12-4-5-13-14(9-12)24-25-23-13/h1-9H,(H2,18,26)(H,23,24,25)(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26178 (2,4-dianilino pyrimidine, 35 | 3-({4-[(2-methyl-1H...) Show SMILES Cc1nc2cccc(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)c2[nH]1 Show InChI InChI=1S/C19H17N7O/c1-11-22-14-6-3-7-15(17(14)23-11)25-16-8-9-21-19(26-16)24-13-5-2-4-12(10-13)18(20)27/h2-10H,1H3,(H2,20,27)(H,22,23)(H2,21,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26160 (2,4-dianilino pyrimidine, 17 | 3-({4-[(5-methanesu...) Show SMILES Cc1ccc(NS(C)(=O)=O)cc1Nc1ccnc(Nc2cccc(c2)C(N)=O)n1 Show InChI InChI=1S/C19H20N6O3S/c1-12-6-7-15(25-29(2,27)28)11-16(12)23-17-8-9-21-19(24-17)22-14-5-3-4-13(10-14)18(20)26/h3-11,25H,1-2H3,(H2,20,26)(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26174 (2,4-dianilino pyrimidine, 31 | 3-({4-[(1-methyl-1H...) Show SMILES Cn1ncc2ccc(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)cc12 Show InChI InChI=1S/C19H17N7O/c1-26-16-10-15(6-5-13(16)11-22-26)23-17-7-8-21-19(25-17)24-14-4-2-3-12(9-14)18(20)27/h2-11H,1H3,(H2,20,27)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26159 (2,4-dianilino pyrimidine, 16 | 3-({2-[(3-carbamoyl...) Show SMILES CN(C)C(=O)c1ccc(C)c(Nc2ccnc(Nc3cccc(c3)C(N)=O)n2)c1 Show InChI InChI=1S/C21H22N6O2/c1-13-7-8-15(20(29)27(2)3)12-17(13)25-18-9-10-23-21(26-18)24-16-6-4-5-14(11-16)19(22)28/h4-12H,1-3H3,(H2,22,28)(H2,23,24,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase LCK (Mus musculus)	BDBM26170 (2,4-dianilino pyrimidine, 27 | 3-({4-[(1-methyl-1H...) Show SMILES Cn1cnc2ccc(Nc3ccnc(Nc4cccc(c4)C(N)=O)n3)cc12 Show InChI InChI=1S/C19H17N7O/c1-26-11-22-15-6-5-14(10-16(15)26)23-17-7-8-21-19(25-17)24-13-4-2-3-12(9-13)18(20)27/h2-11H,1H3,(H2,20,27)(H2,21,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description Lck activity was assessed using a TR-FRET assay in a 384-well plate format. The degree of phosphorylation of Biotinylated substrate was measured usin...				Bioorg Med Chem Lett 17: 4363-8 (2007) Article DOI: 10.1016/j.bmcl.2007.04.029 BindingDB Entry DOI: 10.7270/Q21R6NTD
					More data for this Ligand-Target Pair