Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with all data for entry = 170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200905 (US9533999, i-39) Show SMILES Fc1ccc(CN2c3sccc3S(=O)(=O)CC2=O)cc1OC(F)(F)F Show InChI InChI=1S/C14H9F4NO4S2/c15-9-2-1-8(5-10(9)23-14(16,17)18)6-19-12(20)7-25(21,22)11-3-4-24-13(11)19/h1-5H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50019905 (CHEMBL3287210 | US9533999, ii-4) Show SMILES CC(N1C(=O)CSc2cccnc12)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2OS/c1-10(11-4-2-5-12(8-11)16(17,18)19)21-14(22)9-23-13-6-3-7-20-15(13)21/h2-8,10H,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200937 (US9533999, ii-5) Show SMILES FC(F)(F)c1cc(CN2C(=O)CSc3cccnc23)ccc1Cl Show InChI InChI=1S/C15H10ClF3N2OS/c16-11-4-3-9(6-10(11)15(17,18)19)7-21-13(22)8-23-12-2-1-5-20-14(12)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200946 (US9533999, ii-8) Show SMILES FC(F)(F)S(=O)(=O)c1cc(CN2C(=O)CSc3cccnc23)ccc1Cl Show InChI InChI=1S/C15H10ClF3N2O3S2/c16-10-4-3-9(6-12(10)26(23,24)15(17,18)19)7-21-13(22)8-25-11-2-1-5-20-14(11)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50019903 (CHEMBL3287208 | US9533999, i-40) Show SMILES Fc1ccc(CN2c3ccsc3S(=O)(=O)CC2=O)cc1OC(F)(F)F Show InChI InChI=1S/C14H9F4NO4S2/c15-9-2-1-8(5-11(9)23-14(16,17)18)6-19-10-3-4-24-13(10)25(21,22)7-12(19)20/h1-5H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50019900 (CHEMBL3287205 | US9533999, i-5) Show SMILES Fc1ccc(CN2C(=O)CS(=O)(=O)c3cccnc23)cc1OC(F)(F)F Show InChI InChI=1S/C15H10F4N2O4S/c16-10-4-3-9(6-11(10)25-15(17,18)19)7-21-13(22)8-26(23,24)12-2-1-5-20-14(12)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50019904 (CHEMBL3287209 | US9533999, ii-1) Show SMILES FC(F)(F)Oc1cccc(CN2C(=O)CSc3cccnc23)c1 Show InChI InChI=1S/C15H11F3N2O2S/c16-15(17,18)22-11-4-1-3-10(7-11)8-20-13(21)9-23-12-5-2-6-19-14(12)20/h1-7H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200942 (US9533999, ii-7) Show SMILES FC(F)(F)Sc1cc(CN2C(=O)CSc3cccnc23)ccc1Cl Show InChI InChI=1S/C15H10ClF3N2OS2/c16-10-4-3-9(6-12(10)24-15(17,18)19)7-21-13(22)8-23-11-2-1-5-20-14(11)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200966 (US9533999, ii-17) Show SMILES Fc1ccc(CN2c3scnc3SCC2=O)cc1OC(F)(F)F Show InChI InChI=1S/C13H8F4N2O2S2/c14-8-2-1-7(3-9(8)21-13(15,16)17)4-19-10(20)5-22-11-12(19)23-6-18-11/h1-3,6H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50019906 (CHEMBL3287211 | US9533999, ii-11) Show SMILES OCc1ccc2SCC(=O)N(Cc3ccc(Cl)c(c3)C(F)(F)F)c2n1 Show InChI InChI=1S/C16H12ClF3N2O2S/c17-12-3-1-9(5-11(12)16(18,19)20)6-22-14(24)8-25-13-4-2-10(7-23)21-15(13)22/h1-5,23H,6-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200973 (US9533999, ii-23) Show SMILES CC(N1c2nc(C)sc2SCC1=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H13F3N2OS2/c1-8(10-4-3-5-11(6-10)15(16,17)18)20-12(21)7-22-14-13(20)19-9(2)23-14/h3-6,8H,7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200904 (US9533999, i-38) Show SMILES CC(N1c2sccc2S(=O)(=O)CC1=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C15H12F3NO3S2/c1-9(10-3-2-4-11(7-10)15(16,17)18)19-13(20)8-24(21,22)12-5-6-23-14(12)19/h2-7,9H,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	71	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200971 (US9533999, ii-22) Show SMILES Cc1nc2N(Cc3cccc(c3)C(F)(F)F)C(=O)CSc2s1 Show InChI InChI=1S/C14H11F3N2OS2/c1-8-18-12-13(22-8)21-7-11(20)19(12)6-9-3-2-4-10(5-9)14(15,16)17/h2-5H,6-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200855 (US9533999, i-12) Show SMILES FC(F)(F)Oc1cc(CN2C(=O)CS(=O)(=O)c3cccnc23)ccc1Cl Show InChI InChI=1S/C15H10ClF3N2O4S/c16-10-4-3-9(6-11(10)25-15(17,18)19)7-21-13(22)8-26(23,24)12-2-1-5-20-14(12)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200862 (US9533999, i-18) Show SMILES COC(=O)c1ccc2c(n1)N(Cc1ccc(F)c(OC(F)(F)F)c1)C(=O)CS2(=O)=O Show InChI InChI=1S/C17H12F4N2O6S/c1-28-16(25)11-4-5-13-15(22-11)23(14(24)8-30(13,26)27)7-9-2-3-10(18)12(6-9)29-17(19,20)21/h2-6H,7-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200858 (US9533999, i-15) Show SMILES Fc1ccc(CN2C(=O)CS(=O)(=O)c3cc(Cl)cnc23)cc1OC(F)(F)F Show InChI InChI=1S/C15H9ClF4N2O4S/c16-9-4-12-14(21-5-9)22(13(23)7-27(12,24)25)6-8-1-2-10(17)11(3-8)26-15(18,19)20/h1-5H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50019901 (CHEMBL3287206 | US9533999, i-34) Show SMILES CC(C)c1nc2N(Cc3ccc(F)c(OC(F)(F)F)c3)C(=O)CS(=O)(=O)c2s1 Show InChI InChI=1S/C16H14F4N2O4S2/c1-8(2)14-21-13-15(27-14)28(24,25)7-12(23)22(13)6-9-3-4-10(17)11(5-9)26-16(18,19)20/h3-5,8H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200852 (US9533999, i-9) Show SMILES CC(N1C(=O)CS(=O)(=O)c2cc(Cl)cnc12)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H12ClF3N2O3S/c1-9(10-3-2-4-11(5-10)16(18,19)20)22-14(23)8-26(24,25)13-6-12(17)7-21-15(13)22/h2-7,9H,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200894 (US9533999, i-33) Show SMILES Fc1ccc(CN2c3ncsc3S(=O)(=O)CC2=O)cc1OC(F)(F)F Show InChI InChI=1S/C13H8F4N2O4S2/c14-8-2-1-7(3-9(8)23-13(15,16)17)4-19-10(20)5-25(21,22)12-11(19)18-6-24-12/h1-3,6H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200840 (US9533999, i-2) Show SMILES CC(N1C(=O)CS(=O)(=O)c2cccnc12)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H13F3N2O3S/c1-10(11-4-2-5-12(8-11)16(17,18)19)21-14(22)9-25(23,24)13-6-3-7-20-15(13)21/h2-8,10H,9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200930 (US9533999, i-43) Show SMILES COC(=O)c1cc2N(C(C)c3cccc(c3)C(F)(F)F)C(=O)CS(=O)(=O)c2s1 Show InChI InChI=1S/C17H14F3NO5S2/c1-9(10-4-3-5-11(6-10)17(18,19)20)21-12-7-13(15(23)26-2)27-16(12)28(24,25)8-14(21)22/h3-7,9H,8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200947 (US9533999, ii-9) Show SMILES Fc1ccc(CN2C(=O)CSc3cc(Cl)cnc23)cc1OC(F)(F)F Show InChI InChI=1S/C15H9ClF4N2O2S/c16-9-4-12-14(21-5-9)22(13(23)7-25-12)6-8-1-2-10(17)11(3-8)24-15(18,19)20/h1-5H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200842 (US9533999, i-4) Show SMILES CC(N1C(=O)CS(=O)(=O)c2cccnc12)c1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C16H12ClF3N2O3S/c1-9(10-4-5-12(17)11(7-10)16(18,19)20)22-14(23)8-26(24,25)13-3-2-6-21-15(13)22/h2-7,9H,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200929 (US9533999, i-42) Show SMILES COC(=O)c1cc2N(Cc3cccc(OC(F)(F)F)c3)C(=O)CS(=O)(=O)c2s1 Show InChI InChI=1S/C16H12F3NO6S2/c1-25-14(22)12-6-11-15(27-12)28(23,24)8-13(21)20(11)7-9-3-2-4-10(5-9)26-16(17,18)19/h2-6H,7-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200955 (US9533999, ii-13) Show SMILES FC(F)(F)Oc1cccc(CN2c3scnc3SCC2=O)c1 Show InChI InChI=1S/C13H9F3N2O2S2/c14-13(15,16)20-9-3-1-2-8(4-9)5-18-10(19)6-21-11-12(18)22-7-17-11/h1-4,7H,5-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200870 (US9533999, i-23) Show SMILES Fc1ccc(CN2C(=O)CS(=O)(=O)c3nccnc23)cc1OC(F)(F)F Show InChI InChI=1S/C14H9F4N3O4S/c15-9-2-1-8(5-10(9)25-14(16,17)18)6-21-11(22)7-26(23,24)13-12(21)19-3-4-20-13/h1-5H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200965 (US9533999, ii-16) Show SMILES CC(N1c2scnc2SCC1=O)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C14H11F3N2OS2/c1-8(9-3-2-4-10(5-9)14(15,16)17)19-11(20)6-21-12-13(19)22-7-18-12/h2-5,7-8H,6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200841 (US9533999, i-3) Show SMILES FC(F)(F)c1cc(CN2C(=O)CS(=O)(=O)c3cccnc23)ccc1Cl Show InChI InChI=1S/C15H10ClF3N2O3S/c16-11-4-3-9(6-10(11)15(17,18)19)7-21-13(22)8-25(23,24)12-2-1-5-20-14(12)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200853 (US9533999, i-10) Show SMILES FC(F)(F)c1cc(CN2C(=O)CS(=O)(=O)c3cc(Cl)cnc23)ccc1Cl Show InChI InChI=1S/C15H9Cl2F3N2O3S/c16-9-4-12-14(21-5-9)22(13(23)7-26(12,24)25)6-8-1-2-11(17)10(3-8)15(18,19)20/h1-5H,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200935 (US9533999, ii-3) Show SMILES NC(=O)c1ccc2SCC(=O)N(Cc3ccc(Cl)c(c3)C(F)(F)F)c2n1 Show InChI InChI=1S/C16H11ClF3N3O2S/c17-10-2-1-8(5-9(10)16(18,19)20)6-23-13(24)7-26-12-4-3-11(14(21)25)22-15(12)23/h1-5H,6-7H2,(H2,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200923 (US9533999, i-41) Show SMILES COC(=O)c1cc2N(Cc3cccc(c3)C(F)(F)F)C(=O)CS(=O)(=O)c2s1 Show InChI InChI=1S/C16H12F3NO5S2/c1-25-14(22)12-6-11-15(26-12)27(23,24)8-13(21)20(11)7-9-3-2-4-10(5-9)16(17,18)19/h2-6H,7-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200900 (US9533999, i-37) Show SMILES Cc1nc2N(Cc3cccc(c3)C(F)(F)F)C(=O)CS(=O)(=O)c2s1 Show InChI InChI=1S/C14H11F3N2O3S2/c1-8-18-12-13(23-8)24(21,22)7-11(20)19(12)6-9-3-2-4-10(5-9)14(15,16)17/h2-5H,6-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200896 (US9533999, i-35) Show SMILES CC(C)c1nc2N(Cc3cccc(c3)C(F)(F)F)C(=O)CS(=O)(=O)c2s1 Show InChI InChI=1S/C16H15F3N2O3S2/c1-9(2)14-20-13-15(25-14)26(23,24)8-12(22)21(13)7-10-4-3-5-11(6-10)16(17,18)19/h3-6,9H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200865 (US9533999, i-21) Show SMILES CC(N1C(=O)CS(=O)(=O)c2ncc(Br)cc12)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C16H12BrF3N2O3S/c1-9(10-3-2-4-11(5-10)16(18,19)20)22-13-6-12(17)7-21-15(13)26(24,25)8-14(22)23/h2-7,9H,8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200967 (US9533999, ii-18) Show SMILES CC(C)c1nc2N(Cc3ccc(F)c(OC(F)(F)F)c3)C(=O)CSc2s1 Show InChI InChI=1S/C16H14F4N2O2S2/c1-8(2)14-21-13-15(26-14)25-7-12(23)22(13)6-9-3-4-10(17)11(5-9)24-16(18,19)20/h3-5,8H,6-7H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200952 (US9533999, ii-12) Show SMILES Cc1nc2SCC(=O)N(Cc3cccc(OC(F)(F)F)c3)c2s1 Show InChI InChI=1S/C14H11F3N2O2S2/c1-8-18-12-13(23-8)19(11(20)7-22-12)6-9-3-2-4-10(5-9)21-14(15,16)17/h2-5H,6-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200839 (US9533999, i-1) Show SMILES FC(F)(F)c1cccc(CN2C(=O)CS(=O)(=O)c3cccnc23)c1 Show InChI InChI=1S/C15H11F3N2O3S/c16-15(17,18)11-4-1-3-10(7-11)8-20-13(21)9-24(22,23)12-5-2-6-19-14(12)20/h1-7H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200879 (US9533999, i-27) Show SMILES Cc1nc2c(s1)N(Cc1ccc(F)c(OC(F)(F)F)c1)C(=O)CS2(=O)=O Show InChI InChI=1S/C14H10F4N2O4S2/c1-7-19-12-13(25-7)20(11(21)6-26(12,22)23)5-8-2-3-9(15)10(4-8)24-14(16,17)18/h2-4H,5-6H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200948 (US9533999, ii-10) Show SMILES Brc1cccc(CN2C(=O)CSc3cccnc23)c1 Show InChI InChI=1S/C14H11BrN2OS/c15-11-4-1-3-10(7-11)8-17-13(18)9-19-12-5-2-6-16-14(12)17/h1-7H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200933 (US9533999, ii-2) Show SMILES FC(F)(F)c1cccc(CN2c3scnc3SCC2=O)c1 Show InChI InChI=1S/C13H9F3N2OS2/c14-13(15,16)9-3-1-2-8(4-9)5-18-10(19)6-20-11-12(18)21-7-17-11/h1-4,7H,5-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200968 (US9533999, ii-19) Show SMILES CC(C)c1nc2N(Cc3cccc(c3)C(F)(F)F)C(=O)CSc2s1 Show InChI InChI=1S/C16H15F3N2OS2/c1-9(2)14-20-13-15(24-14)23-8-12(22)21(13)7-10-4-3-5-11(6-10)16(17,18)19/h3-6,9H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200846 (US9533999, i-7) Show SMILES FC(F)(F)c1cccc(CCN2C(=O)CS(=O)(=O)c3cccnc23)c1 Show InChI InChI=1S/C16H13F3N2O3S/c17-16(18,19)12-4-1-3-11(9-12)6-8-21-14(22)10-25(23,24)13-5-2-7-20-15(13)21/h1-5,7,9H,6,8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200861 (US9533999, i-17) Show SMILES FC(F)(F)Oc1cccc(CN2C(=O)CS(=O)(=O)c3cccnc23)c1 Show InChI InChI=1S/C15H11F3N2O4S/c16-15(17,18)24-11-4-1-3-10(7-11)8-20-13(21)9-25(22,23)12-5-2-6-19-14(12)20/h1-7H,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200899 (US9533999, i-36) Show SMILES CC(C)c1nc2N(Cc3cccc(OC(F)(F)F)c3)C(=O)CS(=O)(=O)c2s1 Show InChI InChI=1S/C16H15F3N2O4S2/c1-9(2)14-20-13-15(26-14)27(23,24)8-12(22)21(13)7-10-4-3-5-11(6-10)25-16(17,18)19/h3-6,9H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200970 (US9533999, ii-21) Show SMILES CC(C)c1nc2N(C(C)c3cccc(c3)C(F)(F)F)C(=O)CSc2s1 Show InChI InChI=1S/C17H17F3N2OS2/c1-9(2)15-21-14-16(25-15)24-8-13(23)22(14)10(3)11-5-4-6-12(7-11)17(18,19)20/h4-7,9-10H,8H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200864 (US9533999, i-20) Show SMILES NC(=O)c1ccc2c(n1)N(Cc1ccc(Cl)c(c1)C(F)(F)F)C(=O)CS2(=O)=O Show InChI InChI=1S/C16H11ClF3N3O4S/c17-10-2-1-8(5-9(10)16(18,19)20)6-23-13(24)7-28(26,27)12-4-3-11(14(21)25)22-15(12)23/h1-5H,6-7H2,(H2,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200964 (US9533999, ii-15) Show SMILES Cc1nc2SCC(=O)N(Cc3cccc(c3)C(F)(F)F)c2s1 Show InChI InChI=1S/C14H11F3N2OS2/c1-8-18-12-13(22-8)19(11(20)7-21-12)6-9-3-2-4-10(5-9)14(15,16)17/h2-5H,6-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200874 (US9533999, i-26) Show SMILES Fc1ccc(CN2c3scnc3S(=O)(=O)CC2=O)cc1OC(F)(F)F Show InChI InChI=1S/C13H8F4N2O4S2/c14-8-2-1-7(3-9(8)23-13(15,16)17)4-19-10(20)5-25(21,22)11-12(19)24-6-18-11/h1-3,6H,4-5H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200969 (US9533999, ii-20) Show SMILES CC(C)c1nc2N(Cc3cccc(OC(F)(F)F)c3)C(=O)CSc2s1 Show InChI InChI=1S/C16H15F3N2O2S2/c1-9(2)14-20-13-15(25-14)24-8-12(22)21(13)7-10-4-3-5-11(6-10)23-16(17,18)19/h3-6,9H,7-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM200856 (US9533999, i-13) Show SMILES FC(F)(F)S(=O)(=O)c1cc(CN2C(=O)CS(=O)(=O)c3cccnc23)ccc1Cl Show InChI InChI=1S/C15H10ClF3N2O5S2/c16-10-4-3-9(6-12(10)28(25,26)15(17,18)19)7-21-13(22)8-27(23,24)11-2-1-5-20-14(11)21/h1-6H,7-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...				US Patent US9533999 (2017) BindingDB Entry DOI: 10.7270/Q21V5C4S
					More data for this Ligand-Target Pair

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