Compile Data Set for Download or QSAR

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247019 (US9701638, 10) Show SMILES Oc1cc2ccc(cc2[nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H10FNO2/c16-12-5-3-9(4-6-12)10-1-2-11-8-14(18)15(19)17-13(11)7-10/h1-8,18H,(H,17,19)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	US Patent	n/a	n/a	560	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247018 (US9701638, 9) Show SMILES Oc1cc2cc(ccc2[nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H10FNO2/c16-12-4-1-9(2-5-12)10-3-6-13-11(7-10)8-14(18)15(19)17-13/h1-8,18H,(H,17,19)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	560	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247021 (US9701638, 12) Show SMILES Oc1c(Br)c2ccc(cc2[nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H9BrFNO2/c16-13-11-6-3-9(8-1-4-10(17)5-2-8)7-12(11)18-15(20)14(13)19/h1-7,19H,(H,18,20)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247024 (US9701638, 15) Show SMILES Oc1c(-c2ccccc2)c2ccc(cc2[nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C21H14FNO2/c22-16-9-6-13(7-10-16)15-8-11-17-18(12-15)23-21(25)20(24)19(17)14-4-2-1-3-5-14/h1-12,24H,(H,23,25)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247017 (US9701638, 8) Show SMILES CC.Oc1cc2c(cccc2[nH]c1=O)-c1ccc(F)cc1 Show InChI InChI=1S/C15H10FNO2/c16-10-6-4-9(5-7-10)11-2-1-3-13-12(11)8-14(18)15(19)17-13/h1-8,18H,(H,17,19)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247020 (US9701638, 11) Show SMILES Oc1cc2cccc(-c3ccc(F)cc3)c2[nH]c1=O Show InChI InChI=1S/C15H10FNO2/c16-11-6-4-9(5-7-11)12-3-1-2-10-8-13(18)15(19)17-14(10)12/h1-8,18H,(H,17,19)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247013 (US9701638, 4) Show SMILES Oc1cc2cc(Br)ccc2[nH]c1=O Show InChI InChI=1S/C9H6BrNO2/c10-6-1-2-7-5(3-6)4-8(12)9(13)11-7/h1-4,12H,(H,11,13)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247014 (US9701638, 5) Show SMILES Oc1cc2ccc(Br)cc2[nH]c1=O Show InChI InChI=1S/C9H6BrNO2/c10-6-2-1-5-3-8(12)9(13)11-7(5)4-6/h1-4,12H,(H,11,13)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247015 (US9701638, 6) Show SMILES Oc1cc2cccc(Br)c2[nH]c1=O Show InChI InChI=1S/C9H6BrNO2/c10-6-3-1-2-5-4-7(12)9(13)11-8(5)6/h1-4,12H,(H,11,13)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247016 (US9701638, 7) Show SMILES Oc1c(-c2ccc(F)cc2)c2ccccc2[nH]c1=O Show InChI InChI=1S/C15H10FNO2/c16-10-7-5-9(6-8-10)13-11-3-1-2-4-12(11)17-15(19)14(13)18/h1-8,18H,(H,17,19)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247012 (US9701638, 3) Show SMILES Oc1cc2c(Br)cccc2[nH]c1=O Show InChI InChI=1S/C9H6BrNO2/c10-6-2-1-3-7-5(6)4-8(12)9(13)11-7/h1-4,12H,(H,11,13)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247025 (US9701638, 16) Show SMILES Cc1c(O)c(=O)[nH]c2cc(ccc12)-c1ccc(F)cc1 Show InChI InChI=1S/C16H12FNO2/c1-9-13-7-4-11(10-2-5-12(17)6-3-10)8-14(13)18-16(20)15(9)19/h2-8,19H,1H3,(H,18,20)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247022 (US9701638, 13) Show SMILES Oc1c(-c2ccccc2)c2ccccc2[nH]c1=O Show InChI InChI=1S/C15H11NO2/c17-14-13(10-6-2-1-3-7-10)11-8-4-5-9-12(11)16-15(14)18/h1-9,17H,(H,16,18)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM31148 (3-hydroxyquinolin-2(1H)-one, 2 | US9701638, 1) Show SMILES Oc1cc2ccccc2[nH]c1=O Show InChI InChI=1S/C9H7NO2/c11-8-5-6-3-1-2-4-7(6)10-9(8)12/h1-5,11H,(H,10,12)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MMDB PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM247011 (US9701638, 2) Show SMILES Oc1c(Br)c2ccccc2[nH]c1=O Show InChI InChI=1S/C9H6BrNO2/c10-7-5-3-1-2-4-6(5)11-9(13)8(7)12/h1-4,12H,(H,11,13)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair
Hemagglutinin (Influenza A virus (strain swl A/California/04/2009...)	BDBM31169 (3-hydroxyquinolin-2(1H)-one, 23 | US9701638, 14) Show SMILES Cc1c(O)c(=O)[nH]c2ccccc12 Show InChI InChI=1S/C10H9NO2/c1-6-7-4-2-3-5-8(7)11-10(13)9(6)12/h2-5,12H,1H3,(H,11,13)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	n/a
Rutgers, The State University of New Jersey US Patent					Assay Description The PAN domain has been shown to cleave ssRNA as well as ssDNA. To demonstrate the inhibition of endonuclease cleavage by PAN, a high throughput assa...				US Patent US9701638 (2017) BindingDB Entry DOI: 10.7270/Q2XS5XDC
					More data for this Ligand-Target Pair